专利快速检索-快速检索全球专利，免费商用专利数据库-IPRDB

1. 发明申请

US20140155584A1 CONJUGATED ANTI-CD38 ANTIBODIES 有权
标题翻译：结合抗CD38抗体
公开(公告)号：US20140155584A1
公开(公告)日：2014-06-05
申请号：US13977207
申请日：2011-12-30
申请人： Kathleen Ann Elias , Gregory Landes , Shweta Singh , Wouter Korver , Andrew Walling Drake , Mary Haak-Frendscho , Gyorgy Pal Snell , Vinay Bhaskar
发明人： Kathleen Ann Elias , Gregory Landes , Shweta Singh , Wouter Korver , Andrew Walling Drake , Mary Haak-Frendscho , Gyorgy Pal Snell , Vinay Bhaskar
IPC分类号： C07K16/28
CPC分类号： C07K16/40 , A61K47/6871 , A61K2039/505 , C07K16/2896 , C07K2317/24 , C07K2317/30 , C07K2317/33 , C07K2317/34 , C07K2317/52 , C07K2317/56 , C07K2317/565 , C07K2317/732 , C07K2317/734 , C07K2317/76 , C07K2317/92 , C12N9/99
摘要： Isolated antibodies that bind to human CD38 and cynomolgus CD38 are disclosed. Also disclosed are pharmaceutical compositions comprising the disclosed antibodies, and therapeutic and diagnostic methods for using the disclosed antibodies.
摘要翻译：公开了结合人CD38和食蟹猴CD38的分离的抗体。还公开了包含所公开的抗体的药物组合物，以及使用所公开的抗体的治疗和诊断方法。

2. 发明授权

US08532939B2 System and method for monitoring health of airfoils 有权
标题翻译：用于监测机翼健康的系统和方法
公开(公告)号：US08532939B2
公开(公告)日：2013-09-10
申请号：US12872830
申请日：2010-08-31
申请人： Aninda Bhattacharya , Vinay Bhaskar Jammu , Vivek Venugopal Badami , Venkatesh Rajagopalan , Rahul Srinivas Prabhu , Ajay Kumar Behera , Nidhi Naithani , Mahalakshmi Shunumugam Balasubramaniam
发明人： Aninda Bhattacharya , Vinay Bhaskar Jammu , Vivek Venugopal Badami , Venkatesh Rajagopalan , Rahul Srinivas Prabhu , Ajay Kumar Behera , Nidhi Naithani , Mahalakshmi Shunumugam Balasubramaniam
IPC分类号： G01B3/44 , G01B3/52 , G06F19/00
CPC分类号： F01D21/003 , F05D2260/80 , F05D2270/11
摘要： A system is presented. The system includes a data acquisition system that generates time of arrival (TOA) data corresponding to a plurality of blades in a device, a central processing subsystem that determines features of each of the plurality of blades utilizing the TOA data, and evaluates the health of each of the plurality of blades based upon the determined features.
摘要翻译：提出了一个系统。该系统包括数据采集系统，其生成对应于设备中的多个叶片的到达时间（TOA）数据，中央处理子系统，其使用TOA数据确定多个叶片中的每一个的特征，并评估基于所确定的特征，多个叶片中的每一个。

3. 发明申请

US20110300133A1 CHIMERIC AND HUMANIZED ANTIBODIES TO ALPHA5BETA1 INTEGRIN THAT MODULATE ANGIOGENESIS 有权
标题翻译：对调节血管生成的ALPHA5BETA1整合的重组和人类抗体
公开(公告)号：US20110300133A1
公开(公告)日：2011-12-08
申请号：US13009757
申请日：2011-01-19
申请人： Vanitha RAMAKRISHNAN , David Powers , Dale E. Johnson , Ursula Jeffry , Vinay Bhaskar
发明人： Vanitha RAMAKRISHNAN , David Powers , Dale E. Johnson , Ursula Jeffry , Vinay Bhaskar
IPC分类号： A61K39/395 , A61P27/02 , C07K16/28
CPC分类号： C07K16/2842 , A61K2039/505 , C07K2317/24
摘要： The present invention provides chimeric and humanized antibodies that specifically recognize α5β1 integrin, and methods for using the antibodies for reducing or inhibiting angiogenesis in a tissue. Also provided are methods of determining therapeutically acceptable doses of the antibodies and pharmaceutical compositions including the same.
摘要翻译：本发明提供特异性识别α5和bgr1整联蛋白的嵌合和人源化抗体，以及使用抗体减少或抑制组织中血管发生的方法。还提供了确定抗体的治疗可接受剂量的方法和包括其的药物组合物。

4. 发明申请

US20110211940A1 SYSTEM AND METHOD FOR INSPECTION OF STATOR VANES 有权
标题翻译：用于检查定位器的系统和方法
公开(公告)号：US20110211940A1
公开(公告)日：2011-09-01
申请号：US12714207
申请日：2010-02-26
申请人： Sheri George , Vinay Bhaskar Jammu , Vinod Padmanabhan Kumar , Chayan Mitra , Kunal Ravindra Goray , Achalesh Kumar Pandey , Ravi Yoganatha Babu , Bhasker Rao Keely , Munish Vishwas Inamdar
发明人： Sheri George , Vinay Bhaskar Jammu , Vinod Padmanabhan Kumar , Chayan Mitra , Kunal Ravindra Goray , Achalesh Kumar Pandey , Ravi Yoganatha Babu , Bhasker Rao Keely , Munish Vishwas Inamdar
IPC分类号： F02C7/00 , H04N7/18
CPC分类号： F01D21/003 , F01D25/285 , F05D2260/80 , F05D2270/8041 , G01N21/954 , G01N2021/8887 , Y02T50/671
摘要： Embodiments of the invention include an inspection system to inspect internal components of a compressor of a gas turbine engine. The inspection system includes an image recording assembly having one or more image recording devices, light sources, storage devices, and power supplies. The image recording assembly may be inserted into a compressor without removal of the compressor housing or disassembly of the compressor. The image recording assembly may be removably coupled to a rotary component of the compressor, e.g., a rotor blade, and used to record images of stationary components, e.g., stator vanes, of the compressor. The images may be inspected to identify wear and/or defects in the stationary components, e.g., stator vanes
摘要翻译：本发明的实施例包括检查燃气涡轮发动机的压缩机的内部部件的检查系统。检查系统包括具有一个或多个图像记录装置，光源，存储装置和电源的图像记录组件。图像记录组件可以插入压缩机中，而不需要拆除压缩机壳体或压缩机的拆卸。图像记录组件可以可拆卸地联接到压缩机的旋转部件，例如转子叶片，并用于记录压缩机的静止部件（例如定子叶片）的图像。可以检查图像以识别固定部件（例如定子叶片）中的磨损和/或缺陷

5. 发明申请

US20110054825A1 SYSTEM AND METHOD FOR MANAGING WIND TURBINES 审中-公开
标题翻译：用于管理风力涡轮机的系统和方法
公开(公告)号：US20110054825A1
公开(公告)日：2011-03-03
申请号：US12549447
申请日：2009-08-28
申请人： Ramesh Perla , Vinay Bhaskar Jammu , Nidhi Naithani , Klaus Holtel , Carsten Silcher
发明人： Ramesh Perla , Vinay Bhaskar Jammu , Nidhi Naithani , Klaus Holtel , Carsten Silcher
IPC分类号： G06F19/00 , H02P9/04
CPC分类号： G05B23/0286 , F03D7/042 , F03D17/00 , Y02E10/723
摘要： A method of wind turbine management includes receiving operational information on operational characteristics of a wind turbine. The operational information is analyzed based on a set of rules, and a determination is made as to whether a fault of the wind turbine is resettable. The set of rules may be configured based on operating configuration of the wind turbine.
摘要翻译：风力涡轮机管理的方法包括接收关于风力涡轮机的操作特性的操作信息。基于一组规则分析操作信息，并且确定风力涡轮机的故障是否可重置。该组规则可以基于风力涡轮机的操作配置来配置。

6. 发明授权

US07879987B2 Chimeric and humanized antibodies to α5β1 integrin that modulate angiogenesis 有权
公开(公告)号：US07879987B2
公开(公告)日：2011-02-01
申请号：US11840854
申请日：2007-08-17
申请人： Vanitha Ramakrishnan , David Powers , Dale E. Johnson , Ursula Jeffry , Vinay Bhaskar
发明人： Vanitha Ramakrishnan , David Powers , Dale E. Johnson , Ursula Jeffry , Vinay Bhaskar
IPC分类号： C07H21/00
CPC分类号： C07K16/2842 , A61K2039/505 , C07K2317/24
摘要： The present invention provides chimeric and humanized antibodies that specifically recognize α5β1 integrin, and methods for using the antibodies for reducing or inhibiting angiogenesis in a tissue. Also provided are methods of determining therapeutically acceptable doses of the antibodies and pharmaceutical compositions including the same.

7. 发明授权

US06681215B2 Learning method and apparatus for a causal network 失效
标题翻译：因果网络的学习方法和设备
公开(公告)号：US06681215B2
公开(公告)日：2004-01-20
申请号：US09681336
申请日：2001-03-20
申请人： Vinay Bhaskar Jammu
发明人： Vinay Bhaskar Jammu
IPC分类号： G06F1518
CPC分类号： G06N7/005
摘要： A system and method for improving a causal network is provided. A new apriori probability is determined for a repair or a configuration factor within the causal network and compared to an old apriori probability. If the new apriori probability differs from the old apriori probability by more than a predetermined amount, the causal network is updated. Further, in another aspect, a causal network result is stored for a causal network, wherein the causal network includes a plurality of root causes with a symptom being associated with each of said root causes. An existing link probability is related to the symptom and root cause. An expert result or an actual data result related to each of the symptoms is stored. A new link probability is computed based on the stored causal network result, and expert result or the actual data result.
摘要翻译：提供了一种改善因果网络的系统和方法。对因果网络中的修复或配置因素确定新的先验概率，并与旧的先验概率进行比较。如果新的先验概率与旧的先验概率不同超过预定量，则更新因果网络。此外，在另一方面，为因果网络存储因果网络结果，其中所述因果网络包括具有与每个所述根本原因相关联的症状的多个根本原因。现有的链接概率与症状和根本原因有关。存储与每个症状相关的专家结果或实际数据结果。基于存储的因果网络结果，专家结果或实际数据结果计算新的链路概率。

8. 发明申请

US20140244567A1 SYSTEMS AND METHODS FOR PREDICTION OF TRIPS 有权
标题翻译：用于预测TRIPS的系统和方法
公开(公告)号：US20140244567A1
公开(公告)日：2014-08-28
申请号：US13600387
申请日：2012-08-31
申请人： Ravi Yoganatha Babu , Vinay Bhaskar Jammu , Achalesh Kumar Pandey
发明人： Ravi Yoganatha Babu , Vinay Bhaskar Jammu , Achalesh Kumar Pandey
IPC分类号： G06N5/04
CPC分类号： G06N5/04 , F01D21/00 , F02C9/00 , F05D2260/80 , F05D2270/44 , G05B23/0283
摘要： A system is disclosed. The system includes a processing subsystem that receives component data signals corresponding to a plurality of parameters of a device, wherein the processing subsystem generates one or more sets of state category component data by allocating the component data signals into respective one or more sets of state category component data, determines a plurality of first dynamic thresholds and a plurality of second dynamic thresholds corresponding to at least one of the one or more sets of state category component data based upon a respective set of state category component data in the one or more sets of state category component data and a respective parameter in the plurality of parameters, and determines an impending trip of the device utilizing the plurality of first dynamic thresholds and the plurality of second dynamic thresholds.
摘要翻译：公开了一种系统。该系统包括处理子系统，其接收对应于设备的多个参数的分量数据信号，其中处理子系统通过将分量数据信号分配到相应的一组或多组状态类别中来生成一组或多组状态类别分量数据组件数据，基于一组或多组状态类别组件数据中的相应集合，确定与所述一组或多组状态类别分量数据中的至少一个对应的多个第一动态阈值和多个第二动态阈值状态类别分量数据和多个参数中的相应参数，并且使用多个第一动态阈值和多个第二动态阈值来确定设备的即将跳闸。

9. 发明授权

US08309084B2 Chimeric and humanized antibodies to α5β1 integrin that modulate angiogenesis 有权
标题翻译：对α5和bgr1整联蛋白的嵌合和人源化抗体调节血管发生
公开(公告)号：US08309084B2
公开(公告)日：2012-11-13
申请号：US13009757
申请日：2011-01-19
申请人： Vanitha Ramakrishnan , David Powers , Dale E. Johnson , Ursula Jeffry , Vinay Bhaskar
发明人： Vanitha Ramakrishnan , David Powers , Dale E. Johnson , Ursula Jeffry , Vinay Bhaskar
IPC分类号： A61K39/395 , A61P27/02 , C07K16/28
CPC分类号： C07K16/2842 , A61K2039/505 , C07K2317/24
摘要： The present invention provides chimeric and humanized antibodies that specifically recognize α5β1 integrin, and methods for using the antibodies for reducing or inhibiting angiogenesis in a tissue. Also provided are methods of determining therapeutically acceptable doses of the antibodies and pharmaceutical compositions including the same.
摘要翻译：本发明提供特异性识别α5和bgr1整联蛋白的嵌合和人源化抗体，以及使用抗体减少或抑制组织中血管发生的方法。还提供了确定抗体的治疗可接受剂量的方法和包括其的药物组合物。

10. 发明申请

US20120201827A1 ANTI-CD38 ANTIBODIES 有权
标题翻译：抗CD38抗体
公开(公告)号：US20120201827A1
公开(公告)日：2012-08-09
申请号：US13341860
申请日：2011-12-30
申请人： Kathleen Ann Elias , Gregory Landes , Shweta Singh , Wouter Korver , Andrew Walling Drake , Mary Haak-Frendscho , Gyorgy Pal Snell , Vinay Bhaskar
发明人： Kathleen Ann Elias , Gregory Landes , Shweta Singh , Wouter Korver , Andrew Walling Drake , Mary Haak-Frendscho , Gyorgy Pal Snell , Vinay Bhaskar
IPC分类号： A61K39/395 , A61P29/00 , C07K16/40 , A61P37/06 , C12N5/10 , C12P21/02 , C12N9/99 , A61P1/00 , A61P19/02 , C12N15/13
CPC分类号： C07K16/40 , A61K47/6871 , A61K2039/505 , C07K16/2896 , C07K2317/24 , C07K2317/30 , C07K2317/33 , C07K2317/34 , C07K2317/52 , C07K2317/56 , C07K2317/565 , C07K2317/732 , C07K2317/734 , C07K2317/76 , C07K2317/92 , C12N9/99
摘要： Isolated antibodies that bind to human CD38 and cynomolgus CD38 are disclosed. Also disclosed are pharmaceutical compositions comprising the disclosed antibodies, and therapeutic and diagnostic methods for using the disclosed antibodies.
摘要翻译：公开了结合人CD38和食蟹猴CD38的分离的抗体。还公开了包含所公开的抗体的药物组合物，以及使用所公开的抗体的治疗和诊断方法。

你已经成功收藏专利！

检索式保存成功!

IPRDB

热门服务

关于我们

友情链接

联系方式