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1. 发明授权

US4912034A Immunoassay test device and method 失效
标题翻译：免疫测定装置及方法
公开(公告)号：US4912034A
公开(公告)日：1990-03-27
申请号：US99098
申请日：1987-09-21
申请人： Krishan L. Kalra , Katarzyna Pawlak , Patricia A. Moon , Larry D. French
发明人： Krishan L. Kalra , Katarzyna Pawlak , Patricia A. Moon , Larry D. French
IPC分类号： G01N33/543
CPC分类号： G01N33/54366 , Y10S435/805 , Y10S436/807 , Y10S436/808 , Y10S436/817 , Y10S436/824
摘要： An apparatus is provided for use in an immunoassay for the detection of a target analyte in a liquid sample, comprising a porous reactive filter, having an upper surface and a lower surface, to which is bound an antibody specific for the target antigen; a holder affixed to the porous filter, wherein the upper surface and lower surface of the reactive filter are accessible for passage of liquids through the reactive filter; an absorbent container capable of being detachably attached to the holder; and an absorbent material contained within the container so as to contact the lower surface of the porous filter when the absorbent container is attached to the holder. A prefilter assembly can optionally be attached to the holder so that the prefilter contacts the upper surface of the reactive filter. The prefilter assembly, if present, and the absorbent container can readily be detached from the holder to avoid problems of back flow and to allow ease of storage of the disassembled holder and reactive filter for analysis and comparison with related assays, optionally a series of assays run at different times.
摘要翻译：提供了一种用于免疫测定中用于检测液体样品中的目标分析物的装置，包括具有上表面和下表面的多孔反应性过滤器，结合了靶抗原特异性抗体; 固定在多孔过滤器上的支架，其中反应式过滤器的上表面和下表面可通过液体通过反应式过滤器; 能够可拆卸地附接到保持器的吸收容器; 以及容纳在容器内的吸收材料，以便当吸收容器附接到保持器时与多孔过滤器的下表面接触。预选机组件可以可选地附接到保持器，使得预过滤器接触反应式过滤器的上表面。预过滤器组件（如果存在）和吸收容器可以容易地从保持器分离以避免回流的问题并且允许易于存储拆卸的保持器和反应性过滤器用于分析和与相关测定法进行比较，可选地一系列测定在不同时间运行。

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