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    • 1. 发明授权
    • Systems and methods for designing and ordering polynucleotides
    • 用于设计和排序多核苷酸的系统和方法
    • US07805252B2
    • 2010-09-28
    • US11207151
    • 2005-08-16
    • Claes GustafssonSridhar GovindarajanJon E. NessAlan Marco VillalobosJeremy Minshull
    • Claes GustafssonSridhar GovindarajanJon E. NessAlan Marco VillalobosJeremy Minshull
    • G06F7/00
    • G06F19/26G06F19/18G06F19/20
    • Computer systems, computer program products and methods for designing oligonucleotides are provided. A set of sequence elements is defined. Each sequence element represents an amino acid sequence segment or a nucleic acid sequence segment. The set of sequence elements collectively represent a design nucleic acid sequence. The set of sequence elements are displayed as a plurality icons in a linear or a near linear arrangement such that each respective icon in the plurality of icons uniquely represents a corresponding sequence element in the set of sequence elements. In this representation, neighboring icons in the plurality of icons represent neighboring sequence elements in the set of sequence elements. Each respective icon in the plurality of icons depicts a directional property for the corresponding sequence element in the set of sequence elements. An oligonucleotide selection module is used to identify oligonucleotides in the design nucleic acid sequence.
    • 提供计算机系统,计算机程序产品和设计寡核苷酸的方法。 定义了一组序列元素。 每个序列元件代表氨基酸序列片段或核酸序列片段。 序列元件的集合统称为设计核酸序列。 序列元素的集合被显示为线性或近似线性布置的多个图标,使得多个图标中的每个相应图标唯一地表示序列元素集合中的相应序列元素。 在该表示中,多个图标中的相邻图标表示该组序列元素中的相邻序列元素。 多个图标中的每个相应的图标描绘了序列元素集合中相应的序列元素的方向属性。 寡核苷酸选择模块用于鉴定设计核酸序列中的寡核苷酸。