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1. 发明授权

US07117939B1 Percussion hammer bit retainer apparatus 有权
标题翻译：打击乐锤钻头保持架
公开(公告)号：US07117939B1
公开(公告)日：2006-10-10
申请号：US10718167
申请日：2003-11-20
申请人： Gregory Dee Hawley , John Adam Meyers
发明人： Gregory Dee Hawley , John Adam Meyers
IPC分类号： E21B31/18
CPC分类号： E21B10/36 , E21B17/076
摘要： A bit retention apparatus for the use of retrieving the hammer bit in cases of shankage. The apparatus incorporates a dual sleeve design that fits over the chuck and the extended head section of the hammer bit. The first, “inner” sleeve has two or more ring pieces that fit onto the chuck and have the retention ring fitted into the lower section of the sleeve. The second, “outer” sleeve fits onto the chuck over the inner sleeve to provide protect to the inner sleeve while pulling the shanked bit out of the well bore. Attachment to the bit is accomplished by collars, knobs, or threads on the interior of the sleeves that correspond with holding bands, retention rings, or threads on the bit and chuck.
摘要翻译：一种位置保持装置，用于在锤击的情况下检索锤头。该装置包括一个双套筒设计，其配合在卡盘和锤头的扩展头部分之上。第一个“内”套筒具有两个或更多个装在卡盘上的环件，并且保持环安装在套筒的下部。第二个“外部”套管装配在内套筒上的卡盘上，以将柄部钻头从井筒中拉出来，以保护内套筒。与钻头和卡盘上的保持带，固定环或螺纹相对应的套筒内部的套环，旋钮或螺纹可以实现钻头附件。

2. 发明申请

US20050029695A1 Surface-modified plexifilamentary structures, and compositions therefor 审中-公开
标题翻译：表面改性的丛状结构及其组合物
公开(公告)号：US20050029695A1
公开(公告)日：2005-02-10
申请号：US10668491
申请日：2003-09-23
申请人： Mark Weinberg , Gregory Dee , Jose Rodriguez-Parada
发明人： Mark Weinberg , Gregory Dee , Jose Rodriguez-Parada
IPC分类号： D01D5/11 , D01F6/46 , D01F6/92 , D04H3/16 , D01F6/00
CPC分类号： C08L23/0884 , C08L23/0892 , C08L67/02 , D01D5/11 , D01F6/46 , D01F6/92 , D04H1/724 , Y10T428/2913 , Y10T428/2915 , Y10T428/2973 , Y10T428/2978 , C08L2666/18 , C08L2666/06
摘要： The present invention is concerned with flash-spinning a surface-modified structure such as a plexifilimentary yarn or a microcellular foam.
摘要翻译：本发明涉及一种表面改性结构如聚酯纤维纱或微孔泡沫的闪纺。

3. 发明授权

US06303303B1 Method and system for DNA sequence determination and mutation detection 失效
标题翻译：用于DNA序列测定和突变检测的方法和系统
公开(公告)号：US06303303B1
公开(公告)日：2001-10-16
申请号：US09190756
申请日：1998-11-12
申请人： Ronald J. Green , Vrijmoed Chi , Rodney D. Gilchrist , Gregory Dee , John K. Stevens
发明人： Ronald J. Green , Vrijmoed Chi , Rodney D. Gilchrist , Gregory Dee , John K. Stevens
IPC分类号： C12Q168
CPC分类号： G01N27/44721 , G01N27/44717 , G06F19/18 , G06F19/22 , Y10T436/143333
摘要： Normalization of experimental fragment patterns for nucleic acid polymers having putatively known sequences starts with obtaining at least one raw fragment pattern for the experimental sample. The raw fragment pattern represents the positions of a selected nucleic acid base within the polymer as a function of migration time or distance. This raw fragment pattern is conditioned using conventional baseline correction and noise reduction technique to yield a clean fragment pattern. The clean fragment pattern is then evaluated to determine one or more “normalization coefficients.” These normalization coefficients reflect the displacement, stretching or shrinking, and rate of stretching or shrinking of the clean fragment, or segments thereof, which are necessary to obtain a suitably high degree of correlation between the clean fragment pattern and a standard fragment pattern which represents the positions of the selected nucleic acid base within a standard polymer actually having the known sequence as a function of migration time or distance. The normalization coefficients are then applied to the clean fragment pattern to produce a normalized fragment pattern which is used for base-calling in a conventional manner. This method may be implemented in an apparatus comprising a computer processor programmed to determine normalization coefficients for an experimental fragment pattern. This computer may be separate from the electrophoresis apparatus, or part of an integrated unit.
摘要翻译：具有推定已知序列的核酸聚合物的实验片段模式的归一化从获得实验样品的至少一个原始片段图案开始。原始片段图案表示聚合物内所选择的核酸碱基作为迁移时间或距离的函数的位置。使用常规的基线校正和降噪技术调节该原始片段模式以产生干净的片段模式。然后评估干净的片段模式以确定一个或多个“归一化系数”。这些归一化系数反映了清洁片段或其片段的位移，拉伸或缩小以及拉伸或收缩速率，这些片段或片段是清洁片段图案与标示片段图案之间适当高程度的相关性所必需的，实际上具有已知序列的标准聚合物内所选核酸碱基的位置作为迁移时间或距离的函数。然后将归一化系数应用于干净的片段模式以产生用于以常规方式的基本呼叫的归一化的片段模式。该方法可以在包括被编程为确定实验片段模式的归一化系数的计算机处理器的装置中实现。该计算机可以与电泳装置或集成单元的一部分分开。

4. 发明授权

US5853979A Method and system for DNA sequence determination and mutation detection with reference to a standard 失效
标题翻译：参考标准的DNA序列测定和突变检测的方法和系统
公开(公告)号：US5853979A
公开(公告)日：1998-12-29
申请号：US497202
申请日：1995-06-30
申请人： Ronald J. Green , Vrijmoed Chi , Rodney D. Gilchrist , Gregory Dee , John K. Stevens
发明人： Ronald J. Green , Vrijmoed Chi , Rodney D. Gilchrist , Gregory Dee , John K. Stevens
IPC分类号： C12Q1/68 , G01N27/447 , C12Q1/70 , G01N33/48 , G06K9/00
CPC分类号： G01N27/44721 , G01N27/44717 , G06F19/18 , G06F19/22 , Y10T436/143333
摘要： Normalization of experimental fragment patterns for nucleic acid polymers having putatively known sequences starts with obtaining at least one raw fragment pattern for the experimental sample. The raw fragment pattern represents the positions of a selected nucleic acid base within the polymer as a function of migration time or distance. This raw fragment pattern is conditioned using conventional baseline correction and noise reduction technique to yield a clean fragment pattern. The clean fragment pattern is then evaluated to determine one or more "normalization coefficients." These normalization coefficients reflect the displacement, stretching or shrinking, and rate of stretching or shrinking of the clean fragment, or segments thereof, which are necessary to obtain a suitably high degree of correlation between the clean fragment pattern and a standard fragment pattern which represents the positions of the selected nucleic acid base within a standard polymer actually having the known sequence as a function of migration time or distance. The normalization coefficients are then applied to the clean fragment pattern to produce a normalized fragment pattern which is used for base-calling in a conventional manner. This method may be implemented in an apparatus comprising a computer processor programmed to determine normalization coefficients for an experimental fragment pattern. This computer may be separate from the electrophoresis apparatus, or part of an integrated unit.
摘要翻译：具有推定已知序列的核酸聚合物的实验片段模式的归一化从获得实验样品的至少一个原始片段图案开始。原始片段图案表示聚合物内所选择的核酸碱基作为迁移时间或距离的函数的位置。使用常规的基线校正和降噪技术调节该原始片段模式以产生干净的片段模式。然后评估干净的片段模式以确定一个或多个“归一化系数”。这些归一化系数反映了清洁片段或其片段的位移，拉伸或缩小以及拉伸或收缩速率，这些片段或片段是清洁片段图案与标示片段图案之间适当高程度的相关性所必需的，实际上具有已知序列的标准聚合物内所选核酸碱基的位置作为迁移时间或距离的函数。然后将归一化系数应用于干净的片段模式以产生用于以常规方式的基本呼叫的归一化的片段模式。该方法可以在包括被编程为确定实验片段模式的归一化系数的计算机处理器的装置中实现。该计算机可以与电泳装置或集成单元的一部分分开。

5. 发明授权

US5776767A Virtual DNA sequencer 失效
标题翻译：虚拟DNA测序仪
公开(公告)号：US5776767A
公开(公告)日：1998-07-07
申请号：US570994
申请日：1995-12-12
申请人： John K. Stevens , James M. Dunn , Gregory Dee , James W. Cassidy
发明人： John K. Stevens , James M. Dunn , Gregory Dee , James W. Cassidy
IPC分类号： G01N27/447 , G06F19/00 , C12M3/00
CPC分类号： G01N27/44782
摘要： A virtual DNA sequencer combines a plurality of individual DNA sequencers. Samples of DNA or other nucleic acid from subjects are prepared and allocated in real time to particular lanes or sets of lanes in electrophoresis plates of the individual sequencers, with records kept of the allocations. The data resulting from the electrophoresis runs is collected and collated according to the identities of the subjects. The individual sequencers are networked, and each individual sequencer is preferably equipped with a data buffer large enough to accommodate all or substantially all of a data run, thus protecting the virtual sequencer from loss of valuable data in the event that the network is disrupted for some portion of the time of the data run. In this way, a plurality of sequencers is virtually the same as a single sequencer with a very large number of tracks each of which can run for a much longer sequencing run than an individual sequencer.
摘要翻译：虚拟DNA测序仪组合了多个单独的DNA测序仪。来自受试者的DNA或其他核酸的样品被制备并实时分配到各个定序器的电泳板中的特定泳道或泳道组，并保存有分配记录。根据受试者的身份收集和整理电泳运行产生的数据。各个顺控程序被联网，并且每个单独的定序器优选地配备有足够大的数据缓冲器，以容纳所有或基本上所有的数据运行，从而在网络被中断的情况下保护虚拟定序器免于丢失有价值的数据部分时间的数据运行。以这种方式，多个定序器与具有非常大数量的轨道的单个定序器几乎相同，每个轨道可以运行比单个定序器更长的排序运行。

6. 发明申请

US20060135020A1 Flash spun web containing sub-micron filaments and process for forming same 审中-公开
标题翻译：含有亚微米细丝的闪纺纤维网和其形成方法
公开(公告)号：US20060135020A1
公开(公告)日：2006-06-22
申请号：US11015527
申请日：2004-12-17
申请人： Mark Weinberg , Gregory Dee , Thomas Harding
发明人： Mark Weinberg , Gregory Dee , Thomas Harding
IPC分类号： B32B3/00 , B32B3/26
CPC分类号： D01F6/46 , D01D5/0023 , D01D5/0069 , D01D5/0092 , D01D5/11 , D01F6/04 , D01F6/06 , D01F6/30 , D04H1/724 , D04H3/02 , D04H3/16 , Y10T428/249978 , Y10T442/10 , Y10T442/614 , Y10T442/619 , Y10T442/626
摘要： A nonwoven fibrous structure and process for forming it, which is an interconnecting web of polyolefin filaments having filament widths greater than about 1 micrometer which are further interconnected with webs of smaller polyolefin filaments having filament widths less than about 1 micrometer, wherein the smaller polyolefin filaments comprise a majority of all filaments.
摘要翻译：一种非织造纤维结构及其形成方法，其是具有大于约1微米的丝宽度的聚烯烃长丝的互连网，其进一步与长丝宽度小于约1微米的较小聚烯烃长丝的网互连，其中较小的聚烯烃长丝占所有长丝的大部分。

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