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1. 发明授权

US10226264B2 Apparatus and method for destruction of vascular thrombus 有权
公开(公告)号：US10226264B2
公开(公告)日：2019-03-12
申请号：US13555685
申请日：2012-07-23
申请人： Charles L. McIntosh , Ram H. Paul, Jr. , Darin G. Schaeffer , M. Kem Hawkins , Frank J. Fischer, Jr. , Grant T. Hoffman
发明人： Charles L. McIntosh , Ram H. Paul, Jr. , Darin G. Schaeffer , M. Kem Hawkins , Frank J. Fischer, Jr. , Grant T. Hoffman
IPC分类号： A61H1/00 , A61B17/22 , A61M25/10 , A61M37/00
摘要： A device for thrombolytic therapy is provided. The device includes an elongate catheter with a distal end portion and a proximal end portion and a first lumen extending through both distal and proximal end portions. The distal end portion of the catheter includes an echogenic tubular potion that defines or surrounds a portion of the first lumen. An expandable balloon coaxially surrounds the tubular portion. The tubular portion additionally includes a plurality of indentations defined upon an outer surface thereof.

2. 发明授权

US09833305B2 Vena cava filter with dual retrieval 有权
公开(公告)号：US09833305B2
公开(公告)日：2017-12-05
申请号：US13611821
申请日：2012-09-12
申请人： Frank J. Fischer, Jr.
发明人： Frank J. Fischer, Jr.
IPC分类号： A61F2/00 , A61F2/01
CPC分类号： A61F2/01 , A61F2002/011 , A61F2002/016 , A61F2230/005 , A61F2230/0078
摘要： An intravascular filter assembly has an expanded state for capturing thrombi in a patient's blood vessel, a first a collapsed state for removal from the patient's blood vessel in a first direction and a second collapsed state for removal from the patient's blood vessel in a second direction. A plurality of first struts extends from a first axial side of a fixed hub, and a plurality of second struts extends from the opposite axial side of the fixed hub. An axially movable hub has a first position radially surrounding the tubular body, a second position axially spaced apart from the fixed hub along the first struts, and a third position axially spaced apart from the fixed hub along the second struts. The first struts are collapsed when the movable hub is in the second position, and the second struts are collapsed when the movable hub is in the third position.

3. 发明授权

US09078979B2 Corkscrew injection needle 有权
标题翻译：开瓶器注射针
公开(公告)号：US09078979B2
公开(公告)日：2015-07-14
申请号：US13142496
申请日：2009-12-30
申请人： Frank J. Fischer, Jr.
发明人： Frank J. Fischer, Jr.
IPC分类号： A61M5/32 , A61M39/10 , A61B17/06 , A61M1/00 , A61M5/34
CPC分类号： A61M5/329 , A61B2017/06076 , A61M1/0064 , A61M39/1055 , A61M2005/341 , A61M2039/1027 , A61M2039/1033 , A61M2039/1077
摘要： An injection device including a syringe connectable to a corkscrew injection needle via an adapter is disclosed. The corkscrew needle includes a proximal end and a distal end and a bore formed through the proximal and distal ends, the corkscrew needle terminating with a sharpened tip at the distal end. The syringe includes a barrel and a chamber formed therein for containing an injectable substance. The barrel includes a proximal end, a distal end, and an outlet at the distal end in fluid communication with the chamber. The distal end of the syringe connects to the proximal end of the adapter. The adapter bore provides fluid communication between the syringe and the corkscrew needle. The proximal end of the corkscrew needle is rotatably coupled to distal end of the adapter which allows rotation of the corkscrew needle without rotating the syringe.
摘要翻译：公开了一种注射装置，其包括经由适配器连接到开塞注射针的注射器。开塞针包括近端和远端以及通过近端和远端形成的孔，螺旋针终止于远端处的尖锐尖端。注射器包括在其中形成的用于容纳可注射物质的镜筒和腔室。枪管包括近端，远端和在远端处与腔室流体连通的出口。注射器的远端连接到适配器的近端。适配器孔提供注射器和开塞针之间的流体连通。开塞针的近端可旋转地联接到适配器的远端，允许旋转螺丝针而不旋转注射器。

4. 发明授权

US08882751B2 Wire guided thrombectomy device 有权
标题翻译：导丝血栓切除装置
公开(公告)号：US08882751B2
公开(公告)日：2014-11-11
申请号：US12206931
申请日：2008-09-09
申请人： Frank J. Fischer, Jr.
发明人： Frank J. Fischer, Jr.
IPC分类号： A61B18/18 , A61B18/24
CPC分类号： A61B18/245
摘要： A medical device for removing a thrombus from a blood vessel and a process thereof is presented. The device includes an outer sheath with a plurality of lumens. A wire guide inserted through one of the lumens is used to place the device proximate to a thrombus. An optical fiber placed through a second lumen uses laser input to ablate the thrombus in the distal portion of the second lumen near its distal end. A vacuum coupled to the proximal end of the second lumen is used to remove any ablated residual material. The second lumen may be pivoted around the first lumen to reposition the second lumen proximate to an area of the thrombus that has not yet been ablated.
摘要翻译：提出了用于从血管中除去血栓的医疗装置及其过程。该装置包括具有多个管腔的外护套。插入穿过其中一个管腔的线导向器用于将该装置放置在靠近血栓的位置。通过第二腔放置的光纤使用激光输入来消除靠近其远端的第二腔的远侧部分中的血栓。联接到第二腔的近端的真空用于去除任何烧蚀的残留材料。第二管腔可围绕第一内腔枢转，以使第二内腔重新定位于血栓未被烧蚀的区域附近。

5. 发明授权

US08043282B2 Drainage catheter with extended inflation lumen 有权
标题翻译：排水导管具有延长的充气腔
公开(公告)号：US08043282B2
公开(公告)日：2011-10-25
申请号：US11502779
申请日：2006-08-11
申请人： Frank J. Fischer, Jr. , Tracy E. Willis , Marvin O. Andrews
发明人： Frank J. Fischer, Jr. , Tracy E. Willis , Marvin O. Andrews
IPC分类号： A61M27/00
CPC分类号： A61M25/0017 , A61M25/007 , A61M25/0662 , A61M25/10 , A61M27/00 , A61M2025/0681
摘要： A Foley catheter with a retention balloon includes an elongated inflation tube so that the inflation port used to inflate and deflate the balloon may be maneuvered away from the drainage port of the Foley catheter. If the Foley catheter was placed using a urethral access sheath, the elongated inflation tube allows the surgeon to easily remove the access sheath from the patient.
摘要翻译：具有保持气囊的福利导管包括细长的充气管，使得用于使气囊膨胀和放气的充气端口可以被操纵离开Foley导管的排出口。如果使用尿道通道护套放置Foley导管，则细长的充气管允许外科医生容易地从病人身上移除通路护套。

6. 发明授权

US07766926B2 Sling for supporting tissue 有权
标题翻译：吊for支撑组织
公开(公告)号：US07766926B2
公开(公告)日：2010-08-03
申请号：US10427394
申请日：2003-04-30
申请人： Rodney W. Bosley, Jr. , Umesh H. Patel , Marvin O. Andrews , LiKang Chin , Frank J. Fischer, Jr. , Walter N. Ryan , Peter L. Rosenblatt , J. Stephen Jones
发明人： Rodney W. Bosley, Jr. , Umesh H. Patel , Marvin O. Andrews , LiKang Chin , Frank J. Fischer, Jr. , Walter N. Ryan , Peter L. Rosenblatt , J. Stephen Jones
IPC分类号： A61B17/08 , A61F2/02 , A61F2/00
CPC分类号： A61F2/0045 , A61B17/06109 , A61B2017/0046
摘要： A sling for supporting a urethra in a patient has characteristics for resisting pull-out, roll-over and a combination of both pull-out and roll-over. To facilitate resistance to pull-out, sling material has protuberances or serrations to resist movement once placed in the patient by the surgeon. Improved resistance to roll-over or roll-up is achieved by providing relief on the sling in areas potentially subjected to roll-over forces by endopelvic fascia. The sling may be used on female or male patients, and may be used in conjunction with a wider support portion to support a bladder and a urethra, rather than a urethra alone. The sling may also be used to support other tissues within a patient.
摘要翻译：用于在患者中支撑尿道的吊带具有抵抗拉出，翻转以及拉出和翻转的组合的特征。为了促进拉拔的抗拉力，吊索材料具有突起或锯齿，以便一旦被外科医生放置在病人身上就能抵抗运动。通过在潜在地受到内耳筋膜的翻滚力的区域中的吊带上提供缓解，可以提高对翻滚或卷起的抵抗力。吊索可用于女性或男性患者，并且可以与更宽的支撑部分结合使用以支撑膀胱和尿道，而不是单独使用尿道。吊带也可用于支撑患者体内的其他组织。

7. 发明授权

US07731722B2 Ureteral backstop filter and retrieval device 有权
标题翻译：输尿管支架过滤器和检索装置
公开(公告)号：US07731722B2
公开(公告)日：2010-06-08
申请号：US10902754
申请日：2004-07-28
申请人： Shay Lavelle , Marvin O. Andrews , Frank J. Fischer, Jr. , Walter N. Ryan , Valery Diamant , Stepan Khachin , Nadezda Yasko , Vladimir Khachin
发明人： Shay Lavelle , Marvin O. Andrews , Frank J. Fischer, Jr. , Walter N. Ryan , Valery Diamant , Stepan Khachin , Nadezda Yasko , Vladimir Khachin
IPC分类号： A61B17/22 , A61M29/00
CPC分类号： A61B17/221 , A61B17/32056 , A61B90/39 , A61B2017/2212
摘要： A retrieval device for use in renal, biliary, vascular or other systems of a body includes a collapsible basket in a narrow sheath. A surgeon advances the device beyond an object to be removed from a body, such as a kidneystone, a gallstone, or a thrombus. The surgeon then retracts the sheath or advances the basket from the sheath. The basket deploys only to one side of the sheath. In some embodiments, the periphery of the basket has a flex point to enable the basket to easily collapse into the sheath. If the sheath is adjacent a body vessel, such as a blood vessel or a ureter, the sheath remains adjacent the wall, while the device deploys in such a manner as to seal against the walls of the vessel and block the flow of fragments, emboli, thrombi, or other undesirable objects.
摘要翻译：用于身体的肾，胆管，血管或其他系统的检索装置包括狭窄鞘中的可折叠篮。外科医生将装置推进超过物体以从身体移除，例如儿童骨髓，胆结石或血栓。外科医生然后使护套缩回或者将筐从护套推进。篮子仅部署到护套的一侧。在一些实施例中，篮的周边具有弯曲点，以使篮能够容易地折入鞘中。如果护套与身体容器（例如血管或输尿管）相邻，则护套保持邻近壁，同时该装置以这样的方式展开，以密封血管的壁并阻塞碎片的流动，栓塞，血栓或其他不期望的物体。

8. 发明申请

US20100063488A1 WIRE GUIDED THROMBECTOMY DEVICE 有权
标题翻译：线引导的血栓形成装置
公开(公告)号：US20100063488A1
公开(公告)日：2010-03-11
申请号：US12206931
申请日：2008-09-09
申请人： Frank J. Fischer, JR.
发明人： Frank J. Fischer, JR.
IPC分类号： A61B18/24
CPC分类号： A61B18/245
摘要： A medical device for removing a thrombus from a blood vessel and a process thereof is presented. The device comprises an outer sheath with a plurality of lumens. A wire guide inserted through one of the lumens is used to place the device proximate to a thrombus. An optical fiber placed through a second lumen uses laser input to ablate the thrombus in the proximal portion of the second lumen near its proximal end. A vacuum coupled to the distal end of the second lumen is used to remove any ablated residual material. The second lumen may be pivoted around the first lumen to reposition the second lumen proximate to an area of the thrombus that has not yet been ablated.
摘要翻译：提出了用于从血管中除去血栓的医疗装置及其过程。该装置包括具有多个管腔的外护套。插入穿过其中一个管腔的线导向器用于将该装置放置在靠近血栓的位置。通过第二腔放置的光纤使用激光输入来消除靠近其近端的第二腔的近端部分中的血栓。使用耦合到第二腔的远端的真空来去除任何烧蚀的残留材料。第二管腔可围绕第一内腔枢转，以使第二内腔重新定位于血栓未被烧蚀的区域附近。

9. 发明申请

US20100010499A1 HYDRAULIC GUIDEWIRE ADVANCEMENT SYSTEM 有权
标题翻译：液压指南推进系统
公开(公告)号：US20100010499A1
公开(公告)日：2010-01-14
申请号：US12170923
申请日：2008-07-10
申请人： Frank J. Fischer, JR.
发明人： Frank J. Fischer, JR.
IPC分类号： A61M29/02 , A61M25/08 , A61M25/10 , A61M25/09
CPC分类号： A61M25/09 , A61M2025/09116
摘要： A hydraulic guidewire advancement system for enhancing access through lesions or occlusions in distal regions of a patient's vasculature includes a catheter comprising a sheath, a guidewire lumen, and a proximal catheter port connected to a hydraulic driver. A hydraulic guidewire is coaxially disposed through the guidewire lumen, the hydraulic guidewire comprising a piston movably disposed in the guidewire lumen, the piston forming a seal with an interior surface of the sheath. The hydraulic driver is configured to generate hydraulic pressure against the piston sufficient to advance or retract the hydraulic guidewire relative to the catheter. The hydraulic driver can apply positive or negative pressure to the piston, so as to repeatedly contact and break through the lesion with the distal end of the hydraulic guidewire.
摘要翻译：一种用于增强患者脉管系统的远端区域中的损伤或闭塞的通路的液压导丝进线系统包括导管，其包括护套，导丝管腔和连接到液压驱动器的近端导管端口。液压导丝线同轴地设置穿过导丝管腔，液压导丝线包括可移动地设置在导丝管腔中的活塞，活塞与护套的内表面形成密封。液压驱动器构造成产生足以使液压导丝相对于导管推进或缩回的足够的液压。液压驱动器可以对活塞施加正压或负压，以便与液压导丝的远端反复接触并穿过病变。

10. 发明授权

US06599275B1 Implantable medical device 失效
标题翻译：植入式医疗器械
公开(公告)号：US06599275B1
公开(公告)日：2003-07-29
申请号：US08868518
申请日：1997-06-04
申请人： Frank J. Fischer, Jr.
发明人： Frank J. Fischer, Jr.
IPC分类号： A61M532
CPC分类号： A61M25/0045 , A61F2250/0035 , A61F2250/0067 , A61K51/1282 , A61L29/085 , A61L29/16 , A61L31/16 , A61L2300/406 , A61L2300/42 , A61L2300/45 , A61M31/002 , C08L83/04
摘要： An implantable medical device 10 such as a catheter with a pharmacologically active ingredient layered between outer and inner elongated member tubes 11 and 13 for minimizing the risk of infection or other physiological afflictions associated with the implantation thereof. The outer and inner elongated member tubes include a base material mixed with a bioactive material including, for example, one and/or the other of rifampin and minocycline. An intermediate tube or layer 18 is positioned between and in communication with the outer and inner elongated member tubes 11 and 13. The intermediate tube or layer may also include a base material of, for example, silicone with a pharmacologically active ingredient mixed therein. The slower diffusion rate minocycline is included as or part of the bioactive material in the base material of the outer and inner elongated member tubes. The pharmacologically active ingredient or bioactive material such as a mixture of rifampin and minocycline is included in the base material of the intermediate tube or layer, which permeates through the inner and outer member tubes and diffuses therefrom or therethrough for treating tissues surrounding the catheter concomitantly.
摘要翻译：一种可植入医疗装置10，例如具有药物活性成分的导管，其在细长构件管11和内部细管13之间分层，以最小化与植入相关联的感染风险或其他生理困难。外部和内部细长构件管包括与包括例如利福平和米诺环素中的一种和/或另一种的生物活性材料混合的基础材料。中间管或层18定位在外部和内部细长构件管11和13之间并与之连通。中间管或层还可以包括例如硅氧烷的基础材料，其中混合有药理活性成分。较慢的扩散速率米诺环素作为生物活性物质的一部分包括在外部和内部细长构件管的基材中。药物活性成分或生物活性物质如利福平和米诺环素的混合物被包括在中间管或基层的基材中，该中间管或层的渗透物通过内部和外部构件管并从其中扩散或穿过其中，用于同时治疗导管周围的组织。

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