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    • 3. 发明申请
    • INTEGRATED BIO-REACTOR MONITOR AND CONTROL SYSTEM
    • 集成生物反应器监控和控制系统
    • US20160333303A1
    • 2016-11-17
    • US15222626
    • 2016-07-28
    • Broadley-James Corporation
    • Larry Eugene West
    • C12M1/36G05B19/042G05D21/02C12Q3/00
    • C12M41/48C12Q3/00G05B15/02G05B19/042G05B2219/25425G05D21/02
    • Systems and methods for automatically controlling conditions of a process are disclosed. In one example, a controller is programmed with a sequence of steps and parameters required to carry out a bioreactor process. The controller receives information related to a condition of the process over a first communication network, determines a control signal based on the received information and the programmed process, and sends the control signal over a second communication network to a benchtop utility tower. In one example, the utility tower can include transmitters for temperature, pH, and dissolved oxygen that send information related to a condition of the process to the controller over the first communication network, and an agitation system, a gas control system, a temperature control system and a pump control system that perform a control action based on the control signal affecting the process condition. The utility tower can include a computer with a human-machine interface that communicates with the controller over a third communication network.
    • 公开了用于自动控制过程条件的系统和方法。 在一个示例中,控制器被编程为执行生物反应器过程所需的一系列步骤和参数。 控制器通过第一通信网络接收与过程相关的信息,基于接收的信息和编程的过程来确定控制信号,并通过第二通信网络将控制信号发送到台式公用事业塔。 在一个示例中,公用事业塔可以包括用于温度,pH和溶解氧的发射器,其将与过程相关的信息通过第一通信网络发送到控制器,以及搅拌系统,气体控制系统,温度控制 系统和泵控制系统,其基于影响过程条件的控制信号执行控制动作。 公用事业塔可以包括具有通过第三通信网络与控制器通信的人机接口的计算机。
    • 10. 发明申请
    • MEASUREMENT PROBE WITH HEAT CYCLE EVENT COUNTER
    • 测量探头与热循环事件计数器
    • US20160048752A1
    • 2016-02-18
    • US14801625
    • 2015-07-16
    • BROADLEY-JAMES CORPORATION
    • William E. Reynolds, IVRobert J. GarrahyAndrew W. HaywardRobert FishJared H. NathansonScott T. Broadley
    • G06M1/10
    • A61L2/07A61L2/00A61L9/00G01K13/00G06M1/02G06M1/10G07C3/00
    • A measurement device is disclosed, embodiments of which are adapted to withstand, detect, and record detection of heat cycle events, including autoclave cycles. Embodiments of the measurement device comprise a sensor for measuring a characteristic of a medium and a heat cycle detection unit. Embodiments of the heat cycle detection unit comprise a temperature or atmospheric pressure responsive element, a detection module, data interface, and data memory. In one disclosed embodiment, the temperature or pressure responsive element is configured to respond to a characteristic of a heat cycle event while the heat cycle detection unit is off. In another disclosed embodiment, the detection module is configured to automatically power off the heat cycle detection unit in response to detecting an autoclave cycle. Methods of using the devices are also disclosed.
    • 公开了一种测量装置,其实施例适用于承受,检测和记录包括高压灭菌器循环的热循环事件的检测。 测量装置的实施例包括用于测量介质和热循环检测单元的特性的传感器。 热循环检测单元的实施例包括温度或大气压响应元件,检测模块,数据接口和数据存储器。 在一个所公开的实施例中,温度或压力响应元件被配置为在热循环检测单元关闭时响应热循环事件的特性。 在另一个公开的实施例中,检测模块被配置为响应于检测到高压灭菌器循环来自动关闭热循环检测单元。 还公开了使用该装置的方法。