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1. 发明申请

US20100104474A1 MICRO FLUIDIC DEVICE 有权
公开(公告)号：US20100104474A1
公开(公告)日：2010-04-29
申请号：US12519373
申请日：2007-12-12
申请人： Chris Van Haag , Ronald Cornelis De Gier , Adrianus Wilhelmus Dionisius Maria Van Den Brijgaart , Gheorghe Sorin Stan
发明人： Chris Van Haag , Ronald Cornelis De Gier , Adrianus Wilhelmus Dionisius Maria Van Den Brijgaart , Gheorghe Sorin Stan
IPC分类号： G01N33/00
CPC分类号： F15C5/00 , Y10T137/0971 , Y10T137/3584 , Y10T137/3631 , Y10T137/6416
摘要： The present invention is directed to a micro fluidic device (1) comprising at least one valve/pump-unit (2) with reduced dead volume, wherein the micro fluid device comprises: —a substrate (3), wherein on the lower surface of said substrate (3) at least two micro channels (4) are arranged to direct a fluid sample (5) flow on the substrate (3), whereby said two micro channels (4) are not end-to-end connected and spaced apart by a valve area (6) of said substrate (3); —at least one flexible membrane (7), wherein the flexible membrane (7) is arranged on the lower surface of said substrate (3); —an actuating element (8) with an upper surface (9) adjacent arranged to the flexible membrane (7); —at least one cover element (10) arranged on the lower surface of the flexible membrane (7), wherein the cover element (10) comprises at least one through going cut-out (11) for receiving an actuating element (8), so that movement of said actuating element (8) causes a pump and/or valve action of the adjacent arranged flexible membrane area to cause or stop a directed fluid flow on said substrate (3); so that a fluid flow between said two not end-to-end connected micro channels is directed among the valve area (6) of the lower surface of the substrate (3) and the upper surface of the flexible membrane (7) through a temporally formable channel (12) formed by the flexible membrane (7) covering the valve area (6), whereby a movement of the actuating element (8) towards to the lower surface of the substrate causes a valve action and a movement opposite to the lower surface of the substrate releases a space in a chamber (13) into which the flexible membrane (7) can engage to form the temporally channel (12) and the upper surface (9) of the actuating element (8) covers at least partly the membrane surface (7) at the valve area (6).

2. 发明授权

US08425863B2 Micro fluidic device 有权
标题翻译：微流体装置
公开(公告)号：US08425863B2
公开(公告)日：2013-04-23
申请号：US12519373
申请日：2007-12-12
申请人： Chris Van Haag , Ronald Cornelis De Gier , Adrianus Wilhelmus Dionisius Maria Van Den Brijgaart , Gheorghe Sorin Stan
发明人： Chris Van Haag , Ronald Cornelis De Gier , Adrianus Wilhelmus Dionisius Maria Van Den Brijgaart , Gheorghe Sorin Stan
IPC分类号： G01N33/00
CPC分类号： F15C5/00 , Y10T137/0971 , Y10T137/3584 , Y10T137/3631 , Y10T137/6416
摘要： A micro fluidic device includes a valve/pump-unit with reduced dead volume having a substrate. The lower surface of the substrate includes two micro channels spaced apart by a valve area of the substrate that separates the two micro channels. A flexible membrane is arranged on the lower surface of the substrate facing an actuating element located in a through going cut-out of a cover element. Movement of the actuating element towards and away from the valve area of the substrate causes a pump and/or valve action of the flexible membrane area, respectively, to cause or stop a directed fluid flow between the two micro channels through a channel formed between the valve area of the substrate and the flexible membrane.
摘要翻译：微流体装置包括具有降低的死体积的阀/泵单元，其具有基底。衬底的下表面包括两个微通道，其通过分离两个微通道的衬底的阀区域间隔开。柔性膜布置在基板的下表面上，面向位于盖元件的通过切口中的致动元件。致动元件朝向和远离基板的阀区域的移动分别导致柔性膜区域的泵和/或阀动作，以通过形成在两个微通道之间的通道来引起或停止在两个微通道之间的定向流体流动基板和柔性膜的阀面积。

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