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1. 发明申请

US20110112864A1 AUTOMATED SYSTEM FOR THE COMPARISON OF INDIVIDUAL GENOME, TRANSCRIPTOME, PROTEOME, EPIGENOME, AND METABOLOME DATA WITH DATA FROM BONEMARROW DONOR REGISTERS AND BLOOD BANKS, UMBILICAL CORD BLOOD BANKS AND TISSUE BANKS 有权
标题翻译：自动化系统用于比较单个基因组，转录物，保护因子，重组体和代谢物数据与来自骨髓注射器和血液银行，脐带血液银行和组织银行的数据
公开(公告)号：US20110112864A1
公开(公告)日：2011-05-12
申请号：US12934578
申请日：2010-02-08
申请人： Thomas Klein
发明人： Thomas Klein
IPC分类号： G06Q50/00 , G06Q10/00
CPC分类号： G06F19/322 , G06F19/00 , G06Q50/22 , G06Q50/24 , G16H10/60 , G16H50/70 , Y02A90/22 , Y02A90/26
摘要： The invention relates to a system for the automatic, rapid and dynamic allocation of biological cells for transplantation, therapy, or research purposes between collection centers or banks (storage sites) and hospitals, transplant centers or research facilities, and for monitoring and supporting the processes from request transmission up to delivery of a cell preparation suitable for allogeneic transplantation, via the use of allocated preparations up to tracking the results in the patient and providing these data for statistical and other purposes, as well as assigning molecular-diagnostic results of individuals with the aim of verifying options—even in advance—of transplantations among the inventory of registers or banks. Using said system, it is possible for the first time—even in advance and online and with automatic retries—to propose complete solutions in the form of transplantations in specific and individual cases.
摘要翻译：本发明涉及一种用于在收集中心或银行（存储场所）和医院，移植中心或研究设施之间自动，快速和动态地分配用于移植，治疗或研究目的的生物细胞的系统，以及用于监测和支持过程从请求传输到适用于同种异体移植的细胞制剂的传递，通过使用分配的准备物质来跟踪患者的结果并提供这些数据用于统计学和其他目的，以及将个体的分子诊断结果即使在提前登记册或银行清单中的移植过程中验证选项的目的也是如此。使用所述系统，可以在第一次甚至提前和在线并且自动重试 - 以特定和个别情况下以移植的形式提出完整的解决方案。

2. 发明授权

US08762071B2 Automated system for the selection and conveyance of stored allogeneic biological cells for transplantation, therapy and research 有权
标题翻译：用于选择和输送存储的同种异体生物细胞用于移植，治疗和研究的自动系统
公开(公告)号：US08762071B2
公开(公告)日：2014-06-24
申请号：US13058759
申请日：2009-08-14
申请人： Thomas Klein , Frank Keller
发明人： Thomas Klein , Frank Keller
IPC分类号： G01N33/48 , G06F19/00 , G06Q50/22
CPC分类号： G06F19/322 , G06F19/00 , G06Q50/22 , G06Q50/24 , G16H10/40 , G16H10/60 , G16H50/70
摘要： The invention relates to a system for the automatic, rapid and dynamic conveyance of biological cells for transplant, therapy or research purposes between withdrawalcentres or banks (storage facilities) and clinics, transplant centres or research facilities and also for the monitaring and backing of the processes from request transmission, for supply of a cell specimen which is suitable for the allogeneic transplant, through application of the conveyed specimens to tracking of the results in a patient and the provision of these data for statistical and other purposes. For the first time, the system is able to put forward complete solution proposals for specifically stored transplants online and automatically.
摘要翻译：本发明涉及一种用于在撤离中心或银行（储存设施）和诊所，移植中心或研究设施之间进行移植，治疗或研究目的的生物细胞的自动，快速和动态输送的系统，以及用于监测和支持用于供应适用于同种异体移植的细胞样本的过程，通过将所传送的标本应用于患者的结果的跟踪以及用于统计学和其它目的的这些数据的提供。系统首次能够在线和自动地为特定存储的移植提出完整的解决方案。

3. 发明申请

US20140032123A1 SYSTEM FOR MAKING AVAILABLE INDIVIDUAL OR POOLED, ALSO ANONYMOUS PATIENT DATA ON THE BASIS OF MOLECULAR GENOME, TRANSCRIPTOME, PROTEOME, EPIGENOME, OR METABOLOME DATA 审中-公开
标题翻译：用于制备可供选择的个体或阴道的系统，还有基于分子基因组，转录物，保护物，重组体或代谢物数据的无症状患者数据
公开(公告)号：US20140032123A1
公开(公告)日：2014-01-30
申请号：US13953555
申请日：2013-07-29
申请人： Thomas KLEIN
发明人： Thomas KLEIN
IPC分类号： G06F19/00
CPC分类号： G06F19/3418 , G06Q50/22 , G16H10/60 , G16H50/70
摘要： The invention relates to a system for automatically, rapidly, and dynamically funding biological cells for transplantion, treatment, or research purposes between collection centers or banks (storage places) and hospitals, transplant centers, or research facilities, monitoring and assisting with processes from the transmission of requests, the delivery of cell preparation suitable for allogeneic transplantation, and the use of the found preparations to the monitoring of the result in the patient, and making said data available for statistical and other purposes, wherein samples are taken before and after the transplantation to analyze genomes, proteomes, transcriptomes, epigenomes, and/or metbolomes.
摘要翻译：本发明涉及一种用于在收集中心或银行（储存场所）和医院，移植中心或研究设施之间自动，快速和动态地为生物细胞提供移植，治疗或研究目的的系统，监测和协助来自请求的传送，适用于同种异体移植的细胞制备的递送，以及使用所发现的制剂来监测患者的结果，并使所述数据可用于统计学和其他目的，其中样品在前后移植来分析基因组，蛋白质组，转录组，表观基因组和/或metbolomes。

4. 外观设计

USD694259S1 Display panel of a programmed computer system with graphical user interface 有权
标题翻译：具有图形用户界面的编程计算机系统的显示面板
公开(公告)号：USD694259S1
公开(公告)日：2013-11-26
申请号：US29427267
申请日：2012-07-16
申请人： Thomas Klein
设计人： Thomas Klein

5. 发明授权

US08498882B2 System for making available individual or pooled, also anonymous patient data on the basis of molecular genome, transcriptome, proteome, epigenome, or metabolome data 有权
标题翻译：基于分子基因组，转录组，蛋白质组学，表观基因组或代谢组学数据，提供个体或汇集的匿名患者数据的系统
公开(公告)号：US08498882B2
公开(公告)日：2013-07-30
申请号：US13147835
申请日：2010-02-08
申请人： Thomas Klein
发明人： Thomas Klein
IPC分类号： G06Q10/00 , G06Q50/00 , C12N5/00 , C12N5/071
CPC分类号： G06F19/3418 , G06F19/00 , G06Q50/22 , G16H10/60 , G16H50/70
摘要： The invention relates to a system for automatically, rapidly, and dynamically funding biological cells for transplantion, treatment, or research purposes between collection centers or banks (storage places) and hospitals, transplant centers, or research facilities, monitoring and assisting with processes from the transmission of requests, the delivery of cell preparation suitable for allogeneic transplantation, and the use of the found preparations to the monitoring of the result in the patient, and making said data available for statistical and other purposes, wherein samples are taken before and after the transplantation to analyze genomes, proteomes, transcriptomes, epigenomes, and/or metbolomes.
摘要翻译：本发明涉及一种用于在收集中心或银行（储存场所）和医院，移植中心或研究设施之间自动，快速和动态地为生物细胞提供移植，治疗或研究目的的系统，监测和协助来自请求的传送，适用于同种异体移植的细胞制备的递送，以及使用所发现的制剂来监测患者的结果，并使所述数据可用于统计学和其他目的，其中样品在前后移植来分析基因组，蛋白质组，转录组，表观基因组和/或metbolomes。

6. 发明申请

US20110257999A1 AUTOMATED SYSTEM FOR THE SELECTION AND CONVEYANCE OF STORED ALLOGENEIC BIOLOGICAL CELLS FOR TRANSPLANTATION, THERAPY AND RESEARCH 有权
标题翻译：用于移植，治疗和研究的储存的生物生物细胞的选择和输送的自动化系统
公开(公告)号：US20110257999A1
公开(公告)日：2011-10-20
申请号：US13058759
申请日：2009-08-14
申请人： Thomas Klein , Frank Keller
发明人： Thomas Klein , Frank Keller
IPC分类号： G06Q50/00
CPC分类号： G06F19/322 , G06F19/00 , G06Q50/22 , G06Q50/24 , G16H10/40 , G16H10/60 , G16H50/70
摘要： The invention relates to a system for the automatic, rapid and dynamic conveyance of biological cells for transplant, therapy or research purposes between withdrawalcentres or banks (storage facilities) and clinics, transplant centres or research facilities and also for the monitaring and backing of the processes from request transmission, for supply of a cell specimen which is suitable for the allogeneic transplant, through application of the conveyed specimens to tracking of the results in a patient and the provision of these data for statistical and other purposes. For the first time, the system is able to put forward complete solution proposals for specifically stored transplants online and automatically.
摘要翻译：本发明涉及一种用于在撤离中心或银行（储存设施）和诊所，移植中心或研究设施之间进行移植，治疗或研究目的的生物细胞的自动，快速和动态输送的系统，以及用于监测和支持用于供应适用于同种异体移植的细胞样本的过程，通过将所传送的标本应用于患者的结果的跟踪以及用于统计学和其它目的的这些数据的提供。系统首次能够在线和自动地为特定存储的移植提出完整的解决方案。

7. 发明授权

US08788214B2 Automated system for the comparison of individual genome, transcriptome, proteome, epigenome, and metabolome data with data from bonemarrow donor registers and blood banks, umbilical cord blood banks and tissue banks 有权
标题翻译：用于比较单个基因组，转录组，蛋白质组，表观基因组和代谢组学数据的自动系统与来自bonemarrow供体登记册和血库，脐带血库和组织库的数据
公开(公告)号：US08788214B2
公开(公告)日：2014-07-22
申请号：US12934578
申请日：2010-02-08
申请人： Thomas Klein , Joachim Dudenhausen
发明人： Thomas Klein , Joachim Dudenhausen
IPC分类号： G01N33/48 , G06F19/00 , G06Q50/22
CPC分类号： G06F19/322 , G06F19/00 , G06Q50/22 , G06Q50/24 , G16H10/60 , G16H50/70 , Y02A90/22 , Y02A90/26
摘要： The invention relates to a system for the automatic, rapid and dynamic allocation of biological cells for transplantation, therapy, or research purposes between collection centers or banks (storage sites) and hospitals, transplant centers or research facilities, and for monitoring and supporting the processes from request transmission up to delivery of a cell preparation suitable for allogeneic transplantation, via the use of allocated preparations up to tracking the results in the patient and providing these data for statistical and other purposes, as well as assigning molecular-diagnostic results of individuals with the aim of verifying options—even in advance—of transplantations among the inventory of registers or banks. Using said system, it is possible for the first time—even in advance and online and with automatic retries—to propose complete solutions in the form of transplantations in specific and individual cases.
摘要翻译：本发明涉及一种用于在收集中心或银行（存储场所）和医院，移植中心或研究设施之间自动，快速和动态地分配用于移植，治疗或研究目的的生物细胞的系统，以及用于监测和支持过程从请求传输到适用于同种异体移植的细胞制剂的传递，通过使用分配的准备物质来跟踪患者的结果并提供这些数据用于统计学和其他目的，以及将个体的分子诊断结果即使在提前登记册或银行清单中的移植过程中验证选项的目的也是如此。使用所述系统，可以在第一次甚至提前和在线并且自动重试 - 以特定和个别情况下以移植的形式提出完整的解决方案。

8. 发明申请

US20130132379A1 IDENTIFICATION AND SELECTION OF AT LEAST ONE CORD BLOOD UNIT FOR TRANSPLANTATION 审中-公开
标题翻译：识别和选择最少一个用于移植的牙髓单位
公开(公告)号：US20130132379A1
公开(公告)日：2013-05-23
申请号：US13699147
申请日：2011-05-20
申请人： Thomas Klein
发明人： Thomas Klein
IPC分类号： G06F19/00
CPC分类号： G06F19/32 , G16B20/00 , G16B40/00 , G16B50/00 , G16H10/60
摘要： The invention describes a method for the identification and selection for at least one cord blood unit for a transplantation.
摘要翻译：本发明描述了用于识别和选择用于移植的至少一个脐带血单元的方法。

9. 发明申请

US20130041680A1 AUTOMATED SYSTEM FOR SELECTING AND ALLOCATING STORED ALLOGENEIC BIOLOGICAL CELLS FOR TRANSPLANTATION, THERAPY AND RESEARCH 审中-公开
标题翻译：用于选择和分配存储的同源生物细胞用于移植，治疗和研究的自动化系统
公开(公告)号：US20130041680A1
公开(公告)日：2013-02-14
申请号：US13576886
申请日：2011-02-07
申请人： Thomas Klein
发明人： Thomas Klein
IPC分类号： G06Q50/22
CPC分类号： G06Q10/00 , G06Q50/22
摘要： The invention relates to a system for the automatic, fast and dynamic mediation of biological cells for transplantation, therapy or research purposes for registers of patients having differing indications between extraction centers or banks (deposits) and clinics, transplantation centers or research institutions, service providers (diagnosis, further processing of the preparations and logistics) and the monitoring and support of the processes of requirements transmission, integration from diagnostics technologies and techniques, to further processing, to delivery and payment of a cell preparation suited for allogeneic transplantation or other biological preparation, to the use of the mediated preparation to tracking of the results in patients and to the provision of said data for statistical and other purposes. The system according to the invention is for the first time able to suggest, online and automatically, complete solution proposals for specific stored transplantations for individual patients in extensive registers of patients and to consider prioritized deposits and to create medicinally and logistically advantageous solution proposals when ordering a plurality of preparations. The system is furthermore for the first time able to automatically integrate and coordinate service providers incorporated in the process, such as logistics companies and further processors of the required preparations, into to the process and can conduct all processes and financial transactions as a central tool (platform).
摘要翻译：本发明涉及一种用于移植，治疗或研究目的的生物细胞的自动，快速和动态调停的系统，用于在提取中心或银行（存款）和诊所，移植中心或研究机构，服务提供者之间具有不同适应症的患者的登记（诊断，进一步处理准备和物流）以及监测和支持要求传输过程，诊断技术和技术的整合，进一步处理，交付和支付适合同种异体移植或其他生物制剂的细胞制剂使用介导的准备来跟踪患者的结果，以及为统计学和其他目的提供所述数据。根据本发明的系统首次能够在广泛的患者登记册中针对特定存储的移植的建议，在线和自动地提出完整的解决方案提案，并考虑优先存款，并在订购时创建医学上和后勤性的解决方案提案多种制剂。此外，该系统首次能够自动整合和协调过程中纳入的服务提供商（如物流公司和进一步处理所需准备工作），并将其作为中心工具进行所有流程和金融交易（平台）。

10. 发明申请

US20120123792A1 SYSTEM FOR MAKING AVAILABLE INDIVIDUAL OR POOLED, ALSO ANONYMOUS PATIENT DATA ON THE BASIS OF MOLECULAR GENOME, TRANSCRIPTOME, PROTEOME, EPIGENOME, OR METABOLOME DATA 有权
标题翻译：用于制备可供选择的个体或阴道的系统，还有基于分子基因组，转录物，保护物，重组体或代谢物数据的无症状患者数据
公开(公告)号：US20120123792A1
公开(公告)日：2012-05-17
申请号：US13147835
申请日：2010-02-08
申请人： Thomas Klein
发明人： Thomas Klein
IPC分类号： G06Q50/22
CPC分类号： G06F19/3418 , G06F19/00 , G06Q50/22 , G16H10/60 , G16H50/70
摘要： The invention relates to a system for automatically, rapidly, and dynamically funding biological cells for transplantion, treatment, or research purposes between collection centers or banks (storage places) and hospitals, transplant centers, or research facilities, monitoring and assisting with processes from the transmission of requests, the delivery of cell preparation suitable for allogeneic transplantation, and the use of the found preparations to the monitoring of the result in the patient, and making said data available for statistical and other purposes, wherein samples are taken before and after the transplantation to analyze genomes, proteomes, transcriptomes, epigenomes, and/or metbolomes.
摘要翻译：本发明涉及一种用于在收集中心或银行（储存场所）和医院，移植中心或研究设施之间自动，快速和动态地为生物细胞提供移植，治疗或研究目的的系统，监测和协助来自请求的传送，适用于同种异体移植的细胞制备的递送，以及使用所发现的制剂来监测患者的结果，并使所述数据可用于统计学和其他目的，其中样品在前后移植来分析基因组，蛋白质组，转录组，表观基因组和/或metbolomes。

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