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1. 发明授权

US08469977B2 Endoscopic plication device and method 有权
标题翻译：内镜矫治装置及方法
公开(公告)号：US08469977B2
公开(公告)日：2013-06-25
申请号：US12785268
申请日：2010-05-21
申请人： Daniel J. Balbierz , Dave Cole , Samuel T. Crews , Brett Swope , Andrew Smith , John Lunsford , Fiona Sander
发明人： Daniel J. Balbierz , Dave Cole , Samuel T. Crews , Brett Swope , Andrew Smith , John Lunsford , Fiona Sander
IPC分类号： A61B17/72
CPC分类号： A61B17/1155 , A61B17/0218 , A61B17/068 , A61B17/072 , A61B17/07292 , A61B17/1114 , A61B17/115 , A61B17/1285 , A61B2017/00535 , A61B2017/00827 , A61B2017/07214 , A61B2017/07228 , A61B2017/1139 , A61B2017/1157 , A61B2017/306 , A61F5/0036
摘要： Described herein are endoscopic plicators passed transorally into the stomach and used to plicate stomach tissue by engaging tissue from inside of the stomach and drawing it inwardly. In the disclosed embodiments, the tissue is drawn inwardly into a vacuum chamber, causing sections of serosal tissue on the exterior of the stomach to be positioned facing one another. The disclosed plicators allow the opposed sections of tissue to be moved into contact with one another, and preferably deliver sutures, staples or other means for maintaining contact between the tissue sections at least until serosal bonds form between them. Each of these steps may be performed wholly from the inside of the stomach and thus can eliminate the need for any surgical or laparoscopic intervention. After one or more plications is formed, medical devices may be coupled to the plication(s) for retention within the stomach.
摘要翻译：这里描述的是内窥镜检查器，其通过经腹部通过胃并用于通过从胃内部接合组织并将其向内抽吸来摧毁胃组织。在所公开的实施例中，将组织向内拉入真空室，使得胃外部的浆膜组织的部分彼此相对定位。所公开的调节器允许组织的相对部分彼此移动接触，并且优选地递送缝合线，缝钉或其它装置，用于保持组织切片之间的接触，至少在它们之间形成浆膜粘结。这些步骤中的每一个可以完全从胃内进行，因此可以消除对任何手术或腹腔镜干预的需要。在形成一个或多个脓肿之后，医疗装置可以连接到脓液以保持在胃中。

2. 发明申请

US20130012863A1 RESTRICTIVE AND/OR OBSTRUCTIVE IMPLANT SYSTEM FOR INDUCING WEIGHT LOSS 有权
标题翻译：用于诱导重量损失的限制性和/或阻碍性植入体系
公开(公告)号：US20130012863A1
公开(公告)日：2013-01-10
申请号：US13492732
申请日：2012-06-08
申请人： Richard S. Stack , Daniel J. Balbierz , William L. Athas , John Lunsford , Kevin van Bladel , Ashik Mohan , Samuel T. Crews , Shuji Uemura , Robert H. Hawes
发明人： Richard S. Stack , Daniel J. Balbierz , William L. Athas , John Lunsford , Kevin van Bladel , Ashik Mohan , Samuel T. Crews , Shuji Uemura , Robert H. Hawes
IPC分类号： A61M5/00
CPC分类号： A61F5/0086 , A61B17/00234 , A61B2017/00292 , A61B2017/00827 , A61B2017/00991 , A61F5/0089 , A61M25/0194
摘要： The present application describes an implant system useable for positioning an implant device such as a device useful for restricting passage of ingested food into the stomach. In one embodiment, the disclosed system includes a plurality of anchors that may be coupled to tissue within the stomach, or to a tissue tunnel formed by plicating stomach wall tissue. The anchor includes a loop. During use, the implant device is inserted through the loop and expanded such that it retains its position within the loop until removed. Instruments for implanting and explanting the implant device are also described.
摘要翻译：本申请描述了可用于定位植入装置的植入物系统，例如用于限制摄取的食物进入胃的通道的装置。在一个实施例中，所公开的系统包括可以连接到胃内的组织或通过使胃壁组织变细而形成的组织隧道的多个锚固件。锚包括一个环。在使用期间，植入装置插入通过环并且膨胀使得其保持其在环内的位置，直到移除。还描述了用于植入和外植植入装置的器械。

3. 发明申请

US20120271217A1 SATIATION DEVICES AND METHODS 审中-公开
公开(公告)号：US20120271217A1
公开(公告)日：2012-10-25
申请号：US13535254
申请日：2012-06-27
申请人： Richard S. Stack , Richard A. Glenn , Trevor J. Moody , Fred E. Silverstein , Nathan Every , William S. Eubanks, JR.
发明人： Richard S. Stack , Richard A. Glenn , Trevor J. Moody , Fred E. Silverstein , Nathan Every , William S. Eubanks, JR.
IPC分类号： A61F2/04
CPC分类号： A61F5/0076 , A61F2/04 , A61F2/07 , A61F2/24 , A61F5/0069 , A61F5/0079 , A61F2002/044 , A61F2002/045 , A61F2002/067 , A61F2002/072 , A61F2002/8483 , A61F2250/0039 , A61F2250/0067
摘要： A device for inducing weight loss in a patient includes a tubular prosthesis self-expandable from a collapsed position in which the prosthesis has a first diameter to an expanded position in which the prosthesis has a second, larger, diameter. In a method for inducing weight loss, the prosthesis is placed in the collapsed position and inserted into a stomach of a patient. The prosthesis is allowed to self-expand from the collapsed position to the expanded position and into contact with the walls of the stomach, where it induces feelings of satiety and/or inhibits modulation of satiety-controlling factors such as Ghrelin.

4. 发明申请

US20120116286A1 INTESTINAL SLEEVES AND ASSOCIATED DEPLOYMENT SYSTEMS AND METHODS 有权
标题翻译： INTESTINAL SLEEVES和相关的部署系统和方法
公开(公告)号：US20120116286A1
公开(公告)日：2012-05-10
申请号：US13353258
申请日：2012-01-18
申请人： Michael S. Williams , Daniel W. Fifer , Geoffrey A. Orth , Jeffrey A. Smith , Richard A. Glenn , William L. Athas , Richard S. Stack
发明人： Michael S. Williams , Daniel W. Fifer , Geoffrey A. Orth , Jeffrey A. Smith , Richard A. Glenn , William L. Athas , Richard S. Stack
IPC分类号： A61F2/04
CPC分类号： A61F5/0036 , A61F2/04 , A61F2/07 , A61F2/95 , A61F5/0076 , A61F5/0089 , A61F2002/044 , A61F2002/045
摘要： An intestinal implant includes a proximal anchor self-expandable from a radially compressed position to a radially expandable position for engagement with a wall of the intestinal lumen and a flexible sleeve coupled to the anchor. The sleeve is implanted with the anchor downstream from the pylorus and the sleeve extending further downstream through the intestinal lumen.
摘要翻译：肠植入物包括从径向压缩位置到径向可扩张位置的可自膨胀的近端锚固件，用于与肠腔的壁接合，以及联接到锚的柔性套管。套管被植入幽门下游的锚固件，并且套筒在下游延伸穿过肠腔。

5. 发明申请

US20110192881A1 MULTI-FIRE STAPLING SYSTEMS AND METHODS FOR DELIVERING ARRAYS OF STAPLES 有权
标题翻译：多层消防系统和传送堆叠阵列的方法
公开(公告)号：US20110192881A1
公开(公告)日：2011-08-11
申请号：US13089216
申请日：2011-04-18
申请人： Daniel J. Balbierz , Pablo R. Hambly , Jason S. Stewart , David Cole
发明人： Daniel J. Balbierz , Pablo R. Hambly , Jason S. Stewart , David Cole
IPC分类号： A61B17/068 , A61B17/072
CPC分类号： A61B17/068 , A61B17/072 , A61B17/07207 , A61B17/115 , A61B2017/07214 , A61B2017/07228 , A61B2017/07271 , A61F5/0086
摘要： A staple housing includes an array of staples each in a staple delivery position or “ready position” ready to be fired into target tissue. A staple driver is advanceable to drive the ready-position staples from the staple head into the tissue using staple pushers. During use, the staples in the ready positions are simultaneously fired into the target tissue using the staple pushers, forming an array of staples in the target tissue. After the array has been fired, one or more feed mechanisms within the staple housing advance a second group of staples from one or more staple storage locations into the ready positions in preparation for firing of the second group of staples.
摘要翻译：订书钉壳体包括各自位于钉送出位置的订书钉阵列或准备好被烧制到目标组织中的“就绪位置”。订书钉驱动器可前进，以使用订书钉推动器将订书钉从订书钉驱动到组织中。在使用期间，准备位置中的订书钉使用订书钉推动器同时被烧制到目标组织中，从而在目标组织中形成一排钉。在阵列被点火之后，钉仓壳体内的一个或多个进给机构将第二组订书钉从一个或多个订书钉存储位置推进到就绪位置，以准备第二组钉的点火。

6. 发明授权

US07721932B2 Endoscopic stapling devices and methods 有权
标题翻译：内镜吻合装置及方法
公开(公告)号：US07721932B2
公开(公告)日：2010-05-25
申请号：US12052874
申请日：2008-03-21
申请人： David Cole , Andrew Smith
发明人： David Cole , Andrew Smith
IPC分类号： A61B17/068
CPC分类号： A61B17/072 , A61B17/064 , A61B17/115 , A61B17/32053 , A61B2017/00539 , A61B2017/00818 , A61B2017/07271 , A61B2017/306 , A61F5/0013 , A61F5/0083
摘要： Described herein are endoscopic staplers used to apply one or more fasteners to body tissue. In one embodiment, a fastener-applying device, which is preferably a stapler, is passed transorally into the stomach and used to plicate stomach tissue by engaging tissue from inside of the stomach and drawing it inwardly. In the disclosed embodiments, the tissue is drawn inwardly into a vacuum chamber, causing sections of serosal tissue on the exterior of the stomach to be positioned facing one another. The disclosed staplers allow the opposed sections of tissue to be moved into contact with one another, and preferably deliver staples for maintaining contact between the tissue sections at least until serosal bonds form between them. Each of these steps may be performed wholly from the inside of the stomach and thus can eliminate the need for any surgical or laparoscopic intervention. After one or more plications are formed, medical devices may optionally be coupled to the plication(s) for retention within the stomach.
摘要翻译：这里描述的是用于将一个或多个紧固件应用于身体组织的内窥镜吻合器。在一个实施例中，优选为吻合器的紧固件施加装置通过经腹部通入胃中，并用于通过从胃内部接合组织并将其向内抽吸来摧毁胃组织。在所公开的实施例中，将组织向内拉入真空室，使得胃外部的浆膜组织的部分彼此相对定位。所公开的订书机允许组织的相对部分彼此接触，并且优选地递送用于维持组织部分之间的接触的钉，至少在它们之间形成浆膜粘结。这些步骤中的每一个可以完全从胃内进行，因此可以消除对任何手术或腹腔镜干预的需要。在形成一个或多个脓肿之后，医疗装置可以可选地耦合到脓肿以保持在胃内。

7. 发明授权

US08337567B2 Satiation devices and methods 有权
标题翻译：饱和装置和方法
公开(公告)号：US08337567B2
公开(公告)日：2012-12-25
申请号：US13247377
申请日：2011-09-28
申请人： Richard S. Stack , Richard A. Glenn , Trevor J. Moody , Fred E. Silverstein , Nathan Every , William S. Eubanks, Jr.
发明人： Richard S. Stack , Richard A. Glenn , Trevor J. Moody , Fred E. Silverstein , Nathan Every , William S. Eubanks, Jr.
IPC分类号： A61F2/04 , A61M5/00
CPC分类号： A61F5/0076 , A61F2/04 , A61F2/07 , A61F2/24 , A61F5/0069 , A61F5/0079 , A61F2002/044 , A61F2002/045 , A61F2002/067 , A61F2002/072 , A61F2002/8483 , A61F2250/0039 , A61F2250/0067
摘要： A device for inducing weight loss in a patient includes a tubular prosthesis self-expandable from a collapsed position in which the prosthesis has a first diameter to an expanded position in which the prosthesis has a second, larger, diameter. In a method for inducing weight loss, the prosthesis is placed in the collapsed position and inserted into a stomach of a patient. The prosthesis is allowed to self-expand from the collapsed position to the expanded position and into contact with the walls of the stomach, where it induces feelings of satiety and/or inhibits modulation of satiety-controlling factors such as Ghrelin.
摘要翻译：用于在患者中引起体重减轻的装置包括管状假体，该管状假体可从其中假体具有第一直径到扩张位置的可膨胀位置自动扩张，在该位置假体具有第二较大的直径。在用于引起体重减轻的方法中，假体被置于折叠位置并插入患者的胃中。允许假体从折叠位置自身膨胀到扩张位置并与胃的壁接触，其中它引起饱腹感和/或抑制饱腹感调节因子如Ghrelin的调节。

8. 发明授权

US08206456B2 Restrictive and/or obstructive implant system for inducing weight loss 有权
标题翻译：用于诱导体重减轻的限制性和/或阻塞性植入物系统
公开(公告)号：US08206456B2
公开(公告)日：2012-06-26
申请号：US11439461
申请日：2006-05-23
申请人： Richard S. Stack , Daniel J. Balbierz , William L. Athas , John Lunsford , Kevin van Bladel , Ashik Mohan , Samuel T. Crews , Shuji Uemura , Robert H. Hawes
发明人： Richard S. Stack , Daniel J. Balbierz , William L. Athas , John Lunsford , Kevin van Bladel , Ashik Mohan , Samuel T. Crews , Shuji Uemura , Robert H. Hawes
IPC分类号： A61F2/02
CPC分类号： A61F5/0086 , A61B17/00234 , A61B2017/00292 , A61B2017/00827 , A61B2017/00991 , A61F5/0089 , A61M25/0194
摘要： The present application describes an implant system useable for positioning an implant device such as a device useful for restricting passage of ingested food into the stomach. In one embodiment, the disclosed system includes a plurality of anchors that may be coupled to tissue within the stomach, or to a tissue tunnel formed by plicating stomach wall tissue. The anchor includes a loop. During use, the implant device is inserted through the loop and expanded such that it retains its position within the loop until removed. Instruments for implanting and explanting the implant device are also described.
摘要翻译：本申请描述了可用于定位植入装置的植入物系统，例如用于限制摄取的食物进入胃的通道的装置。在一个实施例中，所公开的系统包括可以连接到胃内的组织或通过使胃壁组织变细而形成的组织隧道的多个锚固件。锚包括一个环。在使用期间，植入装置插入通过环并且膨胀使得其保持其在环内的位置，直到移除。还描述了用于植入和外植植入装置的器械。

9. 发明申请

US20120016287A1 SATIATION DEVICES AND METHODS 有权
标题翻译：舒适装置及方法
公开(公告)号：US20120016287A1
公开(公告)日：2012-01-19
申请号：US13247400
申请日：2011-09-28
申请人： Richard S. Stack , Richard A. Glenn , Trevor J. Moody , Fred E. Silverstein , Nathan Every , William S. Eubanks, JR.
发明人： Richard S. Stack , Richard A. Glenn , Trevor J. Moody , Fred E. Silverstein , Nathan Every , William S. Eubanks, JR.
IPC分类号： A61F2/04
CPC分类号： A61F5/0076 , A61F2/04 , A61F2/07 , A61F2/24 , A61F5/0069 , A61F5/0079 , A61F2002/044 , A61F2002/045 , A61F2002/067 , A61F2002/072 , A61F2002/8483 , A61F2250/0039 , A61F2250/0067
摘要： A device for inducing weight loss in a patient includes a tubular prosthesis self-expandable from a collapsed position in which the prosthesis has a first diameter to an expanded position in which the prosthesis has a second, larger, diameter. In a method for inducing weight loss, the prosthesis is placed in the collapsed position and inserted into a stomach of a patient. The prosthesis is allowed to self-expand from the collapsed position to the expanded position and into contact with the walls of the stomach, where it induces feelings of satiety and/or inhibits modulation of satiety-controlling factors such as Ghrelin.
摘要翻译：用于在患者中引起体重减轻的装置包括管状假体，该管状假体可从其中假体具有第一直径到扩张位置的可膨胀位置自动扩张，在该位置假体具有第二较大的直径。在用于引起体重减轻的方法中，假体被置于折叠位置并插入患者的胃中。允许假体从折叠位置自身膨胀到扩张位置并与胃的壁接触，其中它引起饱腹感和/或抑制饱腹感调节因子如Ghrelin的调节。

10. 发明授权

US08020741B2 Endoscopic stapling devices and methods 有权
标题翻译：内镜吻合装置及方法
公开(公告)号：US08020741B2
公开(公告)日：2011-09-20
申请号：US12050169
申请日：2008-03-18
申请人： David Cole , Andrew Smith
发明人： David Cole , Andrew Smith
IPC分类号： A61B17/068
CPC分类号： A61B17/072 , A61B17/064 , A61B17/115 , A61B17/32053 , A61B2017/00539 , A61B2017/00818 , A61B2017/07271 , A61B2017/306 , A61F5/0013 , A61F5/0083
摘要： Described herein are endoscopic staplers used to apply one or more fasteners to body tissue. In one embodiment, a fastener-applying device, which is preferably a stapler, is passed transorally into the stomach and used to plicate stomach tissue by engaging tissue from inside of the stomach and drawing it inwardly. In the disclosed embodiments, the tissue is drawn inwardly into a vacuum chamber, causing sections of serosal tissue on the exterior of the stomach to be positioned facing one another. The disclosed staplers allow the opposed sections of tissue to be moved into contact with one another, and preferably deliver staples for maintaining contact between the tissue sections at least until serosal bonds form between them. Each of these steps may be performed wholly from the inside of the stomach and thus can eliminate the need for any surgical or laparoscopic intervention. After one or more plications are formed, medical devices may optionally be coupled to the plication(s) for retention within the stomach.
摘要翻译：这里描述的是用于将一个或多个紧固件应用于身体组织的内窥镜吻合器。在一个实施例中，优选为吻合器的紧固件施加装置通过经腹部通入胃中，并用于通过从胃内部接合组织并将其向内抽吸来摧毁胃组织。在所公开的实施例中，将组织向内拉入真空室，使得胃外部的浆膜组织的部分彼此相对定位。所公开的订书机允许组织的相对部分彼此接触，并且优选地递送用于维持组织部分之间的接触的钉，至少在它们之间形成浆膜粘结。这些步骤中的每一个可以完全从胃内进行，因此可以消除对任何手术或腹腔镜干预的需要。在形成一个或多个脓肿之后，医疗装置可以可选地耦合到脓肿以保持在胃内。

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