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1. 发明授权

KR101483647B1 노린재나무 및 황기의 추출물을 포함하는 관절염의 예방 또는 치료용 조성물 및 그 제조방법 有权
标题翻译：用于预防和治疗包含症状提取物的ARTHRITIS的组合物。皮拉索和阿斯卡胶囊及其制备方法
公开(公告)号：KR101483647B1
公开(公告)日：2015-01-16
申请号：KR1020140160920
申请日：2014-11-18
申请人： (주) 와이디생명과학
发明人： 최수임 , 오현욱 , 황승환 , 정경진 , 최승민 , 한지영 , 김재윤 , 최종길
IPC分类号： A61K36/85 , A61K36/481 , A61P19/02 , A61P19/00
CPC分类号： A61K36/481 , A61K36/85
摘要： The present invention relates to a composition containing extracts of Symplocos chinensis and Astragalus membranaceus for preventing or treating arthritis and a method for preparing the same and, more specifically, provides a composition containing, as active ingredients, an extract of Symplocos chinensis and an extract of Astragalus membranaceus for preventing or treating arthritis; and a method for preparing the composition, comprising the steps of: preparing medicinal herbs including Symplocos chinensis and Astragalus membranaceus; and applying water or C_1-4 alcohol to the prepared medicinal herbs, followed by extraction.
摘要翻译：本发明涉及含有中华黄连提取物和黄芪提取物的组合物，其用于预防或治疗关节炎及其制备方法，更具体地说，提供含有作为活性成分的中华西葫芦提取物和用于预防或治疗关节炎的黄芪以及制备所述组合物的方法，包括以下步骤：制备中草药和黄芪的药材; 并向所制备的药用草药中加入水或C_4醇，然后提取。

2. 发明公开

KR1020130089384A 레몬버베나 유래 액티오사이드 함유 추출물 및 이를 포함하는 기능성 화장료 조성물 有权
标题翻译：提取物含有来自LIPPIA CITRIODORA的活性成分和含有它的化妆品组合物
公开(公告)号：KR1020130089384A
公开(公告)日：2013-08-12
申请号：KR1020120010709
申请日：2012-02-02
申请人： (주)모아캠
发明人： 주철규 , 이근하 , 박청 , 조영롱 , 이재성 , 김고운 , 주일우 , 정용철
IPC分类号： A61K36/85 , A61K8/97 , A61P17/00 , A61Q19/00
摘要： PURPOSE: A cosmetic composition is provided to contain a high content of acteoside isolated and purified from Lippia citriodora as an active ingredient, and have effects of antioxidant, whitening, anti-wrinkle, anti-inflammation, antibiotic, improvement of atopy, and UV protection. CONSTITUTION: A manufacturing method of Lippia citiodora extract containing acteoside is comprises: a step of extracting acteoside by adding a solvent to Lippia citriodora, and concentrating; a step of obtaining acteoside fraction by adding more than two kinds of solvents selected from the group comprising of water, ethanol, methanol, butanol, ethyl acetate, ethyl ether, chloroform and hexane to the concentrated extract; a step of removing the organic solvents and manufacturing fraction concentration powder by secondary concentration; a step of removing pigment and chlorophyll using column after dissolving the fraction concentration powder in solvent; a step of recrystalizing the extract, in which the pigment and chlorophyll are removed, by precipitation under the controlled pressure and temperature; and a step of obtaining powder type acteoside by spray drying or freeze drying the precipitated pellet. A functional cosmetic composition comprises Lippia citriodora extract containing the acteoside as an active ingredient. [Reference numerals] (AA) Sample 1 (Sample 5)
摘要翻译：目的：提供一种化妆品组合物，其含有从柠檬提取物中分离和纯化的高含量的肌动蛋白作为活性成分，具有抗氧化，美白，抗皱，抗炎，抗生素，改善特应性和抗紫外线的作用。构成：含有肌动蛋白的Lippia citiodora提取物的制造方法包括：通过向柠檬提取物提取溶剂并浓缩的步骤; 通过向浓缩提取物中加入选自水，乙醇，甲醇，丁醇，乙酸乙酯，乙醚，氯仿和己烷组成的组中的两种以上的溶剂来获得肌苷类成分的步骤; 通过二次浓缩除去有机溶剂并制备级分浓度粉末的步骤; 在将级分浓缩粉末溶解在溶剂中后，使用柱子除去颜料和叶绿素的步骤; 在控制的压力和温度下通过沉淀来除去其中除去颜料和叶绿素的提取物的步骤; 以及通过喷雾干燥或冷冻干燥沉淀的颗粒来获得粉末型acteoside的步骤。功能性化妆品组合物包含含有作为活性成分的所述acteoside的柠檬提取物（Lippia citriodora）提取物。（标号）（AA）样品1（样品5）

3. 发明公开

KR1020120119105A 층꽃풀 추출물 또는 이로부터 분리된 화합물을 함유하는 간독성 질환 예방 및 치료용 조성물 有权
标题翻译：包含来自阴囊炎的提取物的化学保护性药物组合物及其分离的化合物
公开(公告)号：KR1020120119105A
公开(公告)日：2012-10-30
申请号：KR1020110036866
申请日：2011-04-20
申请人： 한국과학기술연구원
发明人： 진창배 , 김형자 , 이용섭 , 정서윤
IPC分类号： A61K36/85 , A61P1/16 , A61P1/00
CPC分类号： A61K36/53
摘要： PURPOSE: A composition for preventing and treating hepatotoxicity diseases containing caryopteris incana extracts or a compound separated from the same is provided to enhance protective effectson hepatic cells. CONSTITUTION: A composition for preventing and treating hepatotoxicity diseases contains caryopteris incana extracts or a compound separated from the same. The caryopteris incana extract is obtained by extracting the caryopteris incana with water, C1-C4 alcohol or a mixed solvent thereof. The alcohol is methanol or ethanol. The caryopteris incana fraction is a fractions obtained by dichloromethane(CH2Cl2), ethyl acetate or butanol. The caryopteris incana extracts are compounds represented by chemical formula 1-10. The hepatotoxicity disease is drug caused liver damage, viral liver damage, hepatitis, liver hardening, liver cancer or hepatic coma. A pharmaceutical composition for preventing and treating the hepatotoxicity diseases includes the compound of the chemical formula 1-10 or salt which is pharmaceutically acceptable.
摘要翻译：目的：提供一种用于预防和治疗含有鳞翅目植物提取物或与其分离的化合物的肝毒性疾病的组合物，以增强对肝细胞的保护作用。构成：用于预防和治疗肝毒性疾病的组合物含有鳞翅目刺槐提取物或从其分离的化合物。通过用水，C 1 -C 4醇或其混合溶剂萃取ary is is，获得ary ana提取物。醇是甲醇或乙醇。鳞翅目分数是通过二氯甲烷（CH 2 Cl 2），乙酸乙酯或丁醇得到的级分。 ary ana提取物是化学式1-10表示的化合物。肝毒性疾病是药物引起肝损害，病毒性肝损伤，肝炎，肝硬化，肝癌或肝昏迷。用于预防和治疗肝毒性疾病的药物组合物包括化学式1-10的化合物或药学上可接受的盐。

4. 发明授权

KR101132040B1 노린재 나무 또는 노린재 나무 잎 추출물을 포함하는 진통제 또는 신경병증성 통증치료제의 조성물 有权
标题翻译：组合物包括提取症状的ALALGESIC或神经痛PAIN。皮拉索或其叶
公开(公告)号：KR101132040B1
公开(公告)日：2012-04-02
申请号：KR1020110035476
申请日：2011-04-18
申请人： (주)프론트바이오
发明人： 서홍원 , 임순성 , 김현정 , 김진규 , 박수현 , 심윤범 , 함연호
IPC分类号： A61K36/85 , A61P25/04 , A61P25/00
摘要： PURPOSE: An analgesic or therapeutic agent containing extract of Symplocos chinensis for. Pilosa (Nakai) Ohwi or leaf thereof is provided to treat neuropathic pain. CONSTITUTION: A composition of an analgesic or therapeutic agent contains Symplocos chinensis for. Pilosa (Nakai) Ohwi and leaf extract thereof as an active ingredient. A food composition for pain mitigation contains the composition. A method for manufacturing the composition comprises: a step of preparing dried Symplocos chinensis for. Pilosa (Nakai) Ohwi and leaves thereof; and a step of adding water and extracting in an aqueous solution at 50-100°C for 1-10 hours.
摘要翻译：目的：一种镇痛剂或治疗剂，含有中华堇菜提取物。 Pilosa（Nakai）提供Ohwi或其叶来治疗神经性疼痛。构成：镇痛剂或治疗剂的组合物含有中华白喉。 Pilosa（Nakai）Ohwi及其叶提取物作为活性成分。用于减轻疼痛的食物组合物包含组合物。一种组合物的制造方法，其特征在于，包括： Pilosa（Nakai）Ohwi和叶子; 和在50-100℃的水溶液中加水并提取1-10小时的步骤。

5. 发明公开

KR1020070068135A 간 질환 예방 및 치료와 간 보호 효과를 갖는 만형자추출물 및 그의 제조 방법 无效
标题翻译：提取物用于预防或治疗肝脏疾病和/或其生产和使用方法的提取物
公开(公告)号：KR1020070068135A
公开(公告)日：2007-06-29
申请号：KR1020050129901
申请日：2005-12-26
申请人： 일동홀딩스(주)
发明人： 유정수 , 이영호 , 노동형 , 홍재선
IPC分类号： A61K36/85 , A61P1/16 , A61P39/06
摘要： An extract of Viticis fructus is provided to have the free radical scavenging capability, be able to lower the AST and ALT values and inhibit the hepatic damage such as infiltration of inflammatory cells and vacuole degeneration of hepatic cells, thereby being used for protecting the liver, and preventing and treating hepatic diseases. The extract of Viticis fructus has prophylactic and therapeutic effect of the hepatic diseases or the hepatic protecting effect and is prepared by extracting Viticis fructus with at least one water-soluble organic solvent selected from the group consisting of methanol, ethanol and acetone to obtain a crude extract, and collecting ingredients, which are soluble in at least one water-insoluble organic solvent selected from the group consisting of chloroform, dichloromethane, ethylacetate, and toluene, from the crude extract.
摘要翻译：提供维生素提取物具有自由基清除能力，能够降低AST和ALT值，抑制炎症细胞浸润和肝细胞液泡变性等肝损伤，从而用于保护肝脏，并预防和治疗肝病。维生素提取物具有肝脏疾病或肝脏保护作用的预防和治疗作用，并且通过用至少一种选自甲醇，乙醇和丙酮的水溶性有机溶剂提取葡萄果实制备，得到粗品从粗提取物中提取和收集可溶于至少一种选自氯仿，二氯甲烷，乙酸乙酯和甲苯的水不溶性有机溶剂的成分。

6. 发明公开

KR1020220029479A 순비기나무 추출물을 포함하는 여성 갱년기 증상 예방 또는 치료용 약학적 조성물 审中-实审
公开(公告)号：KR1020220029479A
公开(公告)日：2022-03-08
申请号：KR1020210114245
申请日：2021-08-27
IPC分类号： A61K36/85 , A61K31/352 , A61P15/12
摘要： 본발명은순비기나무추출물을포함하는여성갱년기증상개선용조성물에관한것이다. 일양상에따른조성물은순비기나무추출물에포함된비텍시카르핀또는비텍신을유효성분으로하며, 상기비텍시카르핀또는비텍신은저농도에서에스트로겐유사활성을나타낼수 있다. 이로인해, 일양상에따른조성물은부작용없이체중증가, 자궁위축등의갱년기증상을효과적으로완화시킬수 있다.

7. 发明公开

KR1020150095001A 호흡기 질환의 예방 또는 치료용 약제학적 조성물 无效
标题翻译：用于预防或治疗呼吸道疾病的药物组合物
公开(公告)号：KR1020150095001A
公开(公告)日：2015-08-20
申请号：KR1020140015999
申请日：2014-02-12
申请人： 씨제이헬스케어 주식회사
发明人： 성하창 , 박숙경 , 김민철 , 이은영 , 성보현 , 주미선
IPC分类号： A61K36/35 , A61K36/85 , A61P11/00
摘要： 본 발명은 COPD, 천식 등의 호흡기 질환의 염증을 억제할 수 있는 조성물에 관한 것으로, 더욱 구체적으로는 만형자의 추출물 및 금은화의 추출물을 유효성분으로 포함하는 호흡기 질환의 예방 또는 치료용 약제학적 조성물 및 호흡기 질환 개선용 기능성 건강식품에 관한 것이다.
摘要翻译：本发明涉及能够抑制呼吸系统疾病如COPD，哮喘等的炎症的组合物，更具体地，涉及含有Vitex rotundifolia提取物和忍冬金属提取物作为预防或治疗呼吸的活性成分的药物组合物疾病和用于减轻呼吸系统疾病的功能性保健食品。

8. 发明公开

KR1020140054277A 건조 추출물들을 생산하는 방법 审中-实审
标题翻译：生产干燥提取物的方法
公开(公告)号：KR1020140054277A
公开(公告)日：2014-05-08
申请号：KR1020147007049
申请日：2012-08-20
申请人： 비오노리카 에스에
发明人： 폽,미햐엘
IPC分类号： A61K36/70 , A61K36/85 , A61K9/20 , A61K9/48 , A61P31/12 , A61P29/00
CPC分类号： A61K36/85 , A23L33/105 , A23V2002/00 , A61K36/185 , A61K36/35 , A61K36/515 , A61K36/70 , A61K2236/33 , A61K2300/00
摘要： 본 발명은 건조 식물 추출물들을 생산하는 방법 및 이를 포함하는 약학적 조제물들에 관한 것이고, 보다 상세하게는 식물(약물)의 에탄올성/수용성 추출물의 적어도 하나를 포함하는 식물성 약제들(phytopharmaceuticals)로서, 식물들은
루멕스 아세토사 L. (
Rumex acetosa L. ),
루멕스 아세토셀라 L. (
Rumex acetosella L. ),
루멕스 오브투시폴리우스 L. (
Rumex obtusifolius L. ),
루멕스 파티엔티아
L. (
Rumex patientia L. ),
및
루멕스 크리스푸스 L. (
Rumex crispus L. )(이하, 본 명세서에서 총체적인 용어 "
루미시스 헤르바 (
Rumicis herba )"라고 언급됨);
베르베나 오피시날리스 (
Verbena officinalis );
삼부쿠스 니그라 (
Sambucus nigra );
프리물라 베리스 (
Primula veris ); 및
젠티아나 루테아 (
Gentiana lutea ) 그리고 그들의 혼합물들로 이루어진 그룹으로부터 선택되는, 식물성 약제들에 관한 것이다. 본 발명은 코와 인후 부위 및/또는 부비강들의 염증성 및/또는 감염성 질환들을 치료하는 약제, 및 식품 보충제에, 또한 그들의 용도에도 관한 것이다.
摘要翻译：本发明涉及一种用于生产植物干性提取物的方法和含有该植物的药物制剂的方法，更具体地说是植物药物，其含有植物（药物）的至少一种乙醇/水提取物，所述植物选自：柳梅属马鞭草黑曲霉报春花和龙胆草及其混合物。本发明还涉及用于治疗鼻部和喉部区域和/或鼻窦炎症和/或感染性疾病的药物及其用途。

9. 发明公开

KR1020080055205A 독활 및 만형자의 혼합 생약 추출물을 유효성분으로함유하는 관절염의 예방 및 치료용 조성물 无效
标题翻译：包含ARALIA CORDATA THUNB和VITEX ROTUNDIFOLIA L.混合提取物的组合物用于预防和治疗ARTHRITIS
公开(公告)号：KR1020080055205A
公开(公告)日：2008-06-19
申请号：KR1020060128211
申请日：2006-12-14
申请人： 경희대학교 산학협력단
发明人： 박동석 , 유명철 , 최도영 , 이재동 , 백용현 , 허정은 , 조용백 , 한창균 , 이해인 , 정기원
IPC分类号： A61K36/25 , A61K36/85 , A61P19/02
摘要： A composition comprising the mixed extracts of Aralia cordata THUNB and Vitex rotundifolia L. fil is provided to suppress edema and pain, inhibit proteoglycan in articular cartilage cell and activity of MMP-1(matrix metalloproteinase-1) and MMP-3, and induce no cytotoxicity and morphological change, so that the composition is useful for preventing and treating arthritis. A pharmaceutical or health food composition for preventing and treating arthritis comprises 0.1-50 wt.% of the mixed extracts of Aralia cordata THUNB and Vitex rotundifolia L. fil which are prepared by extracting them with water, C1-C4 lower alcohol including methanol or ethanol, or a mixed solvent thereof, wherein the arthritis is degenerative arthritis, rheumatoid arthritis or Lupus arthritis; and the daily dosage of the mixed extracts is 0.01mg/kg-10g/kg, preferably 1 mg/kg-1g/kg.
摘要翻译：提供包含Aralia cordata THUNB和Vitex rotundifolia L. fil的混合提取物的组合物，以抑制水肿和疼痛，抑制关节软骨细胞中的蛋白聚糖和MMP-1（基质金属蛋白酶-1）和MMP-3的活性，并诱导无细胞毒性和形态变化，使得该组合物可用于预防和治疗关节炎。用于预防和治疗关节炎的药物或保健食品组合物包括通过用水，C1-C4低级醇（包括甲醇或乙醇）提取它们制备的Aralia cordata THUNB和Vitex rotundifolia L. fil的混合提取物的0.1-50重量％或其混合溶剂，其中所述关节炎是退行性关节炎，类风湿性关节炎或狼疮性关节炎; 混合提取物的日剂量为0.01mg / kg-10g / kg，优选为1mg / kg-1g / kg。

10. 发明公开

KR1020040060323A 유근피 추출물을 포함하는, 갭 결합을 통한 세포간정보전달의 억제 및 항상성의 불균형과 관련된 질환의예방 또는 치료용 조성물 有权
标题翻译：用于预防和治疗与抑制GAP JUNCTIONAL COMMUNICATION和不平衡的家畜疾病相关的疾病的组合物，包含ULMUS MACROCARPA HANCE EXTRACTINTERNAL CELLULAR
公开(公告)号：KR1020040060323A
公开(公告)日：2004-07-06
申请号：KR1020020087093
申请日：2002-12-30
申请人： 재단법인서울대학교산학협력재단
发明人： 이형주 , 이기원 , 김영준 , 이상준 , 강경선
IPC分类号： A61K36/85 , A61K129/00
摘要： PURPOSE: Provided is a composition for preventing and treating disease associated with inhibition of gap junctional internal cellular communication and unbalance of Homeostasis, which composition contains Ulmus macrocarpa HANCE extract and effectively recovers the inhibition of gap junctional internal cellular communication and the unbalance of Homeostasis. It is therefore, used for manufacture of medicaments, processed foods, functional foods, beverages and drinks. CONSTITUTION: A composition for preventing and treating disease associated with inhibition of gap junctional internal cellular communication and unbalance of Homeostasis is characterized by containing, as an active ingredient, an effective amount of Ulmus macrocarpa HANCE extract or its active fraction, and pharmaceutically acceptable carriers. The extract is obtained by extracting Ulmus macrocarpa HANCE with 60% ethanol solution or hot water.
摘要翻译：目的：提供一种预防和治疗与间质连接内部细胞交流抑制和稳态不平衡相关疾病的组合物，该组合物含有榆树枸杞提取物，有效恢复间隙连接内部细胞通讯的抑制和稳态的不平衡。因此，它用于制造药物，加工食品，功能食品，饮料和饮料。构成：用于预防和治疗与间质连接内细胞连通抑制和稳态不平衡有关的疾病的组合物，其特征在于，含有有效量的榆树枸杞提取物或其活性成分和药学上可接受的载体作为活性成分。提取物通过用60％乙醇溶液或热水提取榆树胭脂红获得。

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