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1. 发明公开

KR1020180031438A 생물전환기술을 활용한 천연 아질산염 및 이를 포함한 염지육제품을 발색시키는 방법 有权
标题翻译：一种含菠菜提取物的天然亚硝酸盐和具有相同作用的肉的显色方法
公开(公告)号：KR1020180031438A
公开(公告)日：2018-03-28
申请号：KR1020160120064
申请日：2016-09-20
申请人： 한국식품연구원
发明人： 최윤상 , 전기홍
IPC分类号： A23L13/40 , A23L29/00 , C01B21/50
CPC分类号： A23L13/42 , A23L29/045 , A23V2002/00 , A23V2200/04 , A23V2200/12 , A23V2250/21 , A23Y2220/33 , C01B21/50
摘要： 본발명은시금치추출물을이용한쳔연아질산염및 이를포함하여원료육을발색시키는방법에관한것으로금치를동결건조하여분쇄시킨분말을이용하여시금치추출물을제조하는단계; 및상기시금치추출물에당 및락토바실러스파르시미니스(KCTC 3618)를첨가하여 15 내지 95시간동안 20 내지 35 ℃에서발효시키는단계를포함함으로써, 합성아질산염을대체할수 있는물질로이용되어합성아질산염대신육제품의제조에이용될수 있다.
摘要翻译：本发明包括通过使用该粉末进行粉碎，冷冻干燥，禁闭涉及显色的方法，包括wonryoyuk chyeonyeon亚硝酸盐制备菠菜提取物的步骤和此，使用菠菜提取物; 并且被用作能够在材料，由包括通过加入（KCTC 3618）与菠菜萃取物15至95小时，在20的发酵至35℃的糖和乳杆菌帕尔西米清漆的步骤，替换合成的亚硝酸盐合成亚硝酸盐而不是6 并可用于制造产品。

2. 发明公开

KR1020160055743A 메주를 만드는 방법 无效
标题翻译： MAEJOO的制造方法
公开(公告)号：KR1020160055743A
公开(公告)日：2016-05-18
申请号：KR1020160052905
申请日：2016-04-29
申请人： 서희동
发明人： 서희동
IPC分类号： A23L11/00 , A23L11/20 , A23L29/00
CPC分类号： Y02A40/948 , A23L11/09 , A23L11/20 , A23L29/045 , A23L29/065 , A23V2002/00 , A23V2250/0618 , A23V2250/70
摘要： 본발명은메주를만드는방법에관한것으로, 더욱상세하게는삶은콩에폴리감마글루탐산(Poly-γ-glutamic acid)을생성하는미생물과젖산균류, 곰팡이류또는효모류의발효미생물에의해서순차적으로발효한다음숙성하여메주를만드는방법에관한것이다. 이를위하여본 발명은콩으로부터메주를만드는데있어서, 상기콩의표면에부착된먼지, 흙등의이물질을잘 세척한콩을물과함께솥에넣고삶아서삶은콩을만드는단계와, 상기삶은콩에폴리감마글루탐산(Poly-γ-glutamic acid)을생성하는미생물균주를첨가하고, 온도는 35∼45℃, 습도는 80∼90%에서 16∼60시간동안 1차발효하여 1차발효된콩에젖산균류, 곰팡이류또는효모류중에서한 종류이상의발효미생물을첨가하고마쇄기(磨碎機)에서알갱이상태의콩을마쇄(磨碎)한것을메주고리와같은형틀에서목침이나납작한벽돌처럼덩어리로뭉친것을온도는 25∼35℃, 습도는 75∼85%에서 4∼5일동안 2차발효를하여발효된메주를만드는단계와, 상기 2차발효된메주를 3일간말린메줏덩어리를실내의실온에서 30∼60일간숙성한다음, 햇볕에쬐어바싹말려서완성된메주를만드는단계로이루어진것에특징이있다.
摘要翻译：本发明涉及一种制备Maejoo（发酵大豆块）的方法，更具体地说，涉及通过使用产生聚-γ-谷氨酸的微生物依次发酵煮沸的大豆并发酵乳酸菌，真菌的微生物来制备Maejoo的方法，或酵母，然后熟化发酵的大豆。根据本发明的从大豆制备Maejoo的方法包括：清洁附着在大豆表面的很好的异物如灰尘，土壤等的步骤，将清洁的大豆与水一起放入釜中，并煮沸大豆准备煮大豆; 向煮沸的大豆中加入生产聚-γ-谷氨酸的微生物菌株的步骤，主要在35至45℃的温度和80至90％的湿度下将微生物菌株加入的大豆发酵16至60小时，制备主要发酵的大豆，向主要发酵的大豆中加入一种或多种选自乳酸菌，真菌或酵母的发酵微生物，将发酵微生物和主要发酵大豆的混合物研磨成粒状大豆，使大豆颗粒状状像木枕或平头砖一样在诸如Maejoo环的模具中，其次在25至35℃的温度和75至85％的湿度下将附聚的块发酵4至5个几天准备发酵的Maejoo; 将第二次发酵的Maejoo干燥3天的步骤，室温室内将干燥的Maejoo块块熟化30至60天，并用阳光干燥成熟的Maejoo块，从而制备完成的Maejoo。

3. 发明公开

KR1020150049404A 이소코리놀린을 포함하는 피부 재생, 주름 개선, 항산화 및 피부 미백용 조성물 审中-实审
标题翻译：用于皮肤细胞再生的组合物，抗皱，抗氧化剂和含白蛋白的皮肤白蛋白
公开(公告)号：KR1020150049404A
公开(公告)日：2015-05-08
申请号：KR1020130129938
申请日：2013-10-30
申请人： 주식회사 엘지생활건강
发明人： 김지원 , 진무현 , 박선규
IPC分类号： A61K31/4375 , A61K8/49 , A61P17/00 , A61Q19/02 , A61Q19/08
CPC分类号： A61K31/4355 , A23L29/035 , A23L29/045 , A23V2200/318 , A61K8/4973 , A61Q19/02 , A61Q19/08
摘要： 본발명은하기화학식 1로표현되는화합물또는이의약학적으로허용가능한염을포함하는피부재생, 주름개선, 항산화및 미백용조성물, 특히화장료, 약학또는건강식품용조성물을제공한다. 본발명의화장료, 약학또는건강식품용조성물은부작용이적어인체에안전하면서도우수한피부재생, 주름개선, 항산화및 미백효과를가진다. [화학식 1]
摘要翻译：本发明涉及用于皮肤细胞再生，抗皱，抗氧化和皮肤美白的化妆品，药物或保健食品组合物，包括由化学式1表示的化合物或其药学上可允许的盐。本发明的化妆品，药物或保健食品组合物具有较少的副作用，因此对人体而言是安全的，并且具有优异的皮肤细胞再生，抗皱纹，抗氧化和皮肤美白效果。

4. 发明公开

KR1020150019632A 피부 재생, 주름개선, 항산화, 항염증 및 피부 미백용 조성물 审中-实审
标题翻译：用于皮肤细胞再生，抗皱，抗氧化，抗发炎和皮肤美白的组合物
公开(公告)号：KR1020150019632A
公开(公告)日：2015-02-25
申请号：KR1020130096712
申请日：2013-08-14
申请人： 주식회사 엘지생활건강
发明人： 진무현 , 황승진 , 박선규 , 이상화
IPC分类号： A61K31/4375 , A61K31/435 , A61P17/00
CPC分类号： A61K31/4375 , A23L29/035 , A23L29/045 , A61K8/022 , A61K8/04 , A61K8/4926 , A61K9/06 , A61K9/7023 , A61Q19/02 , A61Q19/08
摘要： 본 발명은 피부 재생, 주름개선, 항산화, 항염증 및 피부 미백용 조성물에 관한 것이다. 본 발명에 따른 임페리얼린은 피부의 섬유아세포의 콜라겐 합성을 촉진하여 피부 재생효과, 주름 개선 효과, 자유 라디칼 생성을 억제하여 항산화 효과, NO 생성을 억제하여 항염증 효과 및 멜라닌 합성을 억제하여 미백 효과를 나타냄으로써 약학적 조성물, 피부외용제, 화장료 조성물 또는 건강식품으로 사용 가능하다.
摘要翻译：本发明涉及一种用于皮肤再生，除皱，抗氧化，抗炎和皮肤美白的组合物。根据本发明的帝王碱通过促进皮肤成纤维细胞的胶原合成，通过控制自由基的产生，抗氧化作用，通过控制NO的产生来发挥抗炎作用，显示出皮肤再生效果和皱纹去除效果，以及通过控制黑色素的合成而产生的皮肤美白效果，因此可用作药物组合物，外用皮肤，化妆品组合物或健康食品。

5. 发明公开

KR1020140102887A 베툴린산을 포함하는 체력 증진용 조성물 无效
标题翻译：补充组合物，包括β-氨基酸
公开(公告)号：KR1020140102887A
公开(公告)日：2014-08-25
申请号：KR1020130016340
申请日：2013-02-15
申请人： 한동대학교 산학협력단 , 우진 비앤지 주식회사
发明人： 김종배 , 김인보 , 정주성 , 정승필
IPC分类号： A61K31/56 , A61K31/58 , A61P43/00
CPC分类号： A61K31/58 , A23L2/52 , A23L29/035 , A23L29/045
摘要： The present invention relates to a composition comprising a betulinic acid or a derivative of the same for enhancing physical strength. The composition of the present invention has an excise performance enhancing ability, an endurance enhancing ability, and stress controlling ability. The betulinic acid of the present invention is a compound having a structure of the following chemical formula 1. The betulinic acid of the present invention is derived from nature or is chemically synthesized for usage. In addition, the betulinic acid derivative of the present invention has a hydroxyl group or a carboxyl group of a betulinic acid substituted. The betulinic acid derivative of the present invention is nature-derived or chemically synthesized to be applied.
摘要翻译：本发明涉及包含桦木酸或其衍生物以增强体力的组合物。本发明的组合物具有消耗性能提高能力，耐久性提高能力和应力控制能力。本发明的桦木酸是具有以下化学式1的结构的化合物。本发明的桦木酸来源于天然或化学合成用于使用。此外，本发明的桦木酸衍生物具有取代的桦木酸的羟基或羧基。本发明的桦木酸衍生物是自然衍生的或化学合成的以施用。

6. 发明公开

KR1020140050939A 티에노피리돈 유도체를 유효성분으로 포함하는 혈소판 응집 억제용 조성물 无效
标题翻译：包含三烯吡啶衍生物的组合物用于抑制片剂聚集
公开(公告)号：KR1020140050939A
公开(公告)日：2014-04-30
申请号：KR1020120117370
申请日：2012-10-22
申请人： 동국대학교 산학협력단
发明人： 이무열 , 류영추 , 장경화
IPC分类号： A61K31/4743 , A61P7/02 , A61P7/00
CPC分类号： A61K31/4365 , A23L29/035 , A23L29/045 , A23L29/055 , Y10S514/824
摘要： The present invention relates to a composition comprising a thienopyridone derivative as an active ingredient for inhibiting platelet aggregation. The thienopyridone derivative according to the present invention can be used as a composition for inhibiting platelet aggregation and as a composition for preventing or treating thrombotic diseases since the thienopyridone derivative has an excellent effect for inhibiting platelet aggregation induced by thrombin.
摘要翻译：本发明涉及包含噻吩并吡啶酮衍生物作为抑制血小板聚集的活性成分的组合物。根据本发明的噻吩并吡酮衍生物可用作抑制血小板聚集的组合物和用作预防或治疗血栓形成疾病的组合物，因为噻吩并吡啶酮衍生物对于抑制凝血酶诱导的血小板聚集具有极好的效果。

7. 发明公开

KR1020130131797A 당세라마이드 유도체를 포함하는 기억력 개선, 인지능력 개선, 치매 예방 또는 치료 효과를 나타내는 약학적 조성물 有权
标题翻译：用于改善记忆和认知能力的药物组合物，以及预防或治疗包含葡萄糖胺衍生物的阿尔茨海默病
公开(公告)号：KR1020130131797A
公开(公告)日：2013-12-04
申请号：KR1020120055639
申请日：2012-05-24
申请人： (주) 노바렉스 , 이화여자대학교 산학협력단
发明人： 오세관 , 정재철
IPC分类号： A61K31/70 , A61K31/202 , A61K31/20 , A61P25/28
CPC分类号： A61K31/7028 , A23L29/035 , A23L29/045 , A23V2200/322
摘要： Glucoceramide of the present invention has the effect of treating dementia by improving memory and the effect of degrading the generation of inflammation enzymes in the hippocampus region. Accordingly, the glucoceramide and glucoceramide derivatives of the present invention can be used in pharmaceutical compositions for improving memory, preventing and treating dementia and functional health supplements for improving memory and cognitive functions, and preventing and treating dementia.
摘要翻译：本发明的甘露可酰胺具有通过改善记忆和降低海马区炎症酶的产生的作用来治疗痴呆的作用。因此，本发明的糖皮质激素和糖皮质激素衍生物可用于改善记忆，预防和治疗痴呆症和功能性健康补充剂用于改善记忆和认知功能以及预防和治疗痴呆的药物组合物中。

8. 发明公开

KR1020130083797A 피부 주름 개선 및 탄력 증진용 조성물 审中-实审
标题翻译：用于改善皮肤皱纹和增强弹性的组合物
公开(公告)号：KR1020130083797A
公开(公告)日：2013-07-23
申请号：KR1020120047639
申请日：2012-05-04
申请人： 주식회사 엘지생활건강
发明人： 진무현 , 박선규 , 황승진
IPC分类号： A61K31/437 , A61K31/403 , A61K31/19 , A61P17/00
CPC分类号： A61K31/437 , A23L29/035 , A23L29/045 , A23V2200/318 , A61K8/022 , A61K8/04 , A61K8/4926 , A61K9/06 , A61K9/7023 , A61Q19/08
摘要： PURPOSE: A composition for reducing skin wrinkles and enhancing elasticity is provided to be used as a pharmaceutical composition, a skin external application, a cosmetic composition, or a health food as tabersonine HCl promotes collagen synthesis of fibroblast of skin, suppresses activity of collagenase to improve elasticity of skin, removes wrinkles, and suppresses melanin production to have a whitening effect. CONSTITUTION: A pharmaceutical composition for reducing skin wrinkles and enhancing elasticity includes a compound represented by Formula 1 as an active ingredient. The active ingredient is included at a content of 0.0001wt% to 10wt% based on the total wt% of the composition. A skin external application for reducing skin wrinkles and enhancing elasticity includes a compound represented by Formula 1 as an active ingredient. A cosmetic compound for reducing skin wrinkles and enhancing elasticity includes a compound represented by Formula 1 as an active ingredient. A health food for reducing skin wrinkles and enhancing elasticity includes a compound represented by Formula 1 as an active ingredient.
摘要翻译：目的：提供一种用于减少皮肤皱纹和增强弹性的组合物，用作药物组合物，皮肤外用剂，化妆品组合物或保健食品，作为帕金森氏HCl，促进皮肤成纤维细胞的胶原合成，抑制胶原酶的活性改善皮肤弹性，消除皱纹，抑制黑色素生成，使其发白。构成：用于减少皮肤皱纹和增强弹性的药物组合物包括由式1表示的化合物作为活性成分。基于组合物的总重量％，活性成分的含量为0.0001重量％至10重量％。用于减少皮肤皱纹和增强弹性的皮肤外用剂包括由式1表示的化合物作为活性成分。用于减少皮肤皱纹和增强弹性的化妆品化合物包括由式1表示的化合物作为活性成分。用于减少皮肤皱纹和增强弹性的保健食品包括由式1表示的化合物作为活性成分。

9. 发明公开

KR1020130083773A 피부 주름 개선 및 탄력 증진용 조성물 有权
标题翻译：用于改善皮肤皱纹和增强弹性的组合物
公开(公告)号：KR1020130083773A
公开(公告)日：2013-07-23
申请号：KR1020120039945
申请日：2012-04-17
申请人： 주식회사 엘지생활건강
发明人： 진무현 , 박선규 , 황승진
IPC分类号： A61K31/407 , A61K8/49 , A61P17/00 , A61Q19/08
CPC分类号： A61K31/407 , A23L29/035 , A23L29/045 , A23V2200/318 , A61K8/022 , A61K8/04 , A61K8/4973 , A61K9/06 , A61K9/7023 , A61Q19/08
摘要： PURPOSE: A composition for improving an anti-wrinkling property and skin elasticity is provided to promote collagen synthesis of fibroblasts using crotaline and to improve the anti-wrinkling property and skin elasticity, thereby being used as a pharmaceutical product, a cosmetic material, or a food composition. CONSTITUTION: A pharmaceutical composition for improving an anti-wrinkling property and skin elasticity contains 0.0001-10 wt% of a compound of chemical formula 1. The pharmaceutical composition improves the anti-wrinkling benefit and skin elasticity by promoting the synthesis of collagen. An external usage for skin formulation to improve the anti-wrinkling property and skin elasticity contains within the compound. A cosmetic composition for improving the anti-wrinkling property and skin elasticity contains within the compound. A health food for improving the anti-wrinkling property and skin elasticity contains within the compound.
摘要翻译：目的：提供一种用于改善抗皱性和皮肤弹性的组合物，以促进使用溴巴胺的成纤维细胞的胶原合成，并提高抗起皱性和皮肤弹性，从而用作药物产品，化妆品材料或食物成分。构成：用于提高抗皱性和皮肤弹性的药物组合物含有化学式1化合物的0.0001-10重量％。药物组合物通过促进胶原的合成来提高抗皱效果和皮肤弹性。化妆品中含有皮肤配方以提高抗皱性和皮肤弹性的外用用途。用于提高抗皱性和皮肤弹性的化妆品组合物含有化合物。用于改善抗皱性和皮肤弹性的保健食品包含在化合物内。

10. 发明公开

KR1020130048355A 2,4,6,8-테트라키스-(2-메톡시페닐)-3,7-디아자바이시클로(3.3.1)노난-9-원을 유효성분으로 함유하는 암 질환의 예방 및 치료용 조성물 有权
标题翻译：包含2,4,6,8-四氮杂（2-甲氧基苯基）-3,7-二氮杂双环[3.3.1] NONAN-9-ONE的组合物作为用于治疗和预防癌症疾病的活性成分
公开(公告)号：KR1020130048355A
公开(公告)日：2013-05-10
申请号：KR1020110113167
申请日：2011-11-02
申请人： 인제대학교 산학협력단
发明人： 김동규 , 정지형 , 박동호 , 파라마시밤파르티반 , 장신 , 황지영 , 이명진
IPC分类号： A61K31/437 , C07D487/04 , C07D471/04 , A61P35/00
CPC分类号： A61K31/4375 , A23L29/035 , A23L29/045 , A23V2200/308 , A61K9/0095 , A61K9/08 , A61K9/10 , A61K9/14 , A61K9/20 , A61K9/48
摘要： PURPOSE: A composition containing 2,4,6,8-tetrakis (2-methoxyphenyl)-3,7-diazabicyclo[3.3.1] nonan-9-one for preventing and treating cancer is provided to induce cancer cell apoptosis. CONSTITUTION: A composition for preventing and treating cancer contains 2,4,6,8-tetrakis (2-methoxyphenyl)-3,7-diazabicyclo[3.3.1] nonan-9-one of chemical formula 1, or a pharmaceutically acceptable salt, an optical isomer, a stereomer, and a polymorph thereof as an active ingredient. The cancer includes uterine cervix cancer, colon cancer, anal cancer, esophageal cancer, pancreatic cancer, stomach cancer, kidney cancer, tongue cancer, oral cancer, skin cancer, uterine cancer, breast cancer, lymph gland cancer, thyroid cancer, prostate cancer, liver cancer, leukemia, skin cancer, colon carcinoma, brain tumor, bladder cancer, ovarian cancer, or gallbladder cancer. The composition induces cancer cell apoptosis. The composition suppresses DNA synthesis and causes oxidative stress. The composition includes apoptosis through mitochondrial membrane depolarization.
摘要翻译：目的：提供含有用于预防和治疗癌症的2,4,6,8-四（2-甲氧基苯基）-3,7-二氮杂双环[3.3.1]壬烷-9-酮的组合物以诱导癌细胞凋亡。构成：用于预防和治疗癌症的组合物含有化学式1的2,4,6,8-四（2-甲氧基苯基）-3,7-二氮杂双环[3.3.1]壬烷-9-酮或其药学上可接受的盐，光学异构体，立体异构体和其多晶型物作为活性成分。癌症包括子宫颈癌，结肠癌，肛门癌，食管癌，胰腺癌，胃癌，肾癌，舌癌，口腔癌，皮肤癌，子宫癌，乳腺癌，淋巴腺癌，甲状腺癌，前列腺癌，肝癌，白血病，皮肤癌，结肠癌，脑肿瘤，膀胱癌，卵巢癌或胆囊癌。该组合物诱导癌细胞凋亡。该组合物抑制DNA合成并引起氧化应激。该组合物包括通过线粒体膜去极化的凋亡。

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