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    • 1. 发明公开
    • 폴리페놀계 화합물을 함유하는 퇴행성 뇌질환의 예방 또는치료용 조성물
    • 包含用于预防或治疗神经变性疾病的聚苯醚化合物的组合物
    • KR1020090078939A
    • 2009-07-21
    • KR1020080004805
    • 2008-01-16
    • 한국화학연구원한국식품연구원
    • 김영섭유시용연규환홍경식이병회유미영최연희김현기박우규고우석권대영하태열
    • A61K31/192A61K31/045A61K31/343A61P25/28
    • A composition for preventing and treating neutodegenerative disease, which contains a polyphenol compound as an active ingredient is provided to have the effects of beta-amyloid coagulation inhibition, caspase-3 activity suppression and acetylcholinesterase activation suppression. A composition for preventing and treating neurodegenerative diseases comprises salvianolic acid, bakuchiol, epsilon-viniferin, rhapontigenin, piceatannol, luteolin, myricetin, or their mixture as an active ingredient. The neurodegenerative diseases are Alzheimer's disease, Pick's disease, Creutzfeldt-jakob, Parkinson's disease, Lou Gehrig's Disease, or Huntington's disease. The composition suppresses BACE-1[beta-site APP(amyloid precursor protein)-cleaving enzyme 1], caspase or acetylcholine esterase. The composition further comprises medicinal herb. The medicinal herb is Salviae Miltiorrhizae Radix, Psoraleae Semen, Vitidis Fructus, Rhei Rhizoma, Digitalis Folium, Schizonepeta Herba, Taraxaci Herba, Humuli Herba, Lonicerae Folium or their mixture.
    • 提供含有多酚化合物作为活性成分的用于预防和治疗神经变性疾病的组合物,以具有β-淀粉样蛋白凝结抑制,半胱天冬酶-3活性抑制和乙酰胆碱酯酶活化抑制的作用。 用于预防和治疗神经变性疾病的组合物包括salvianolic acid,bakuchiol,ε-viniferin,rhapontigenin,piceatannol,木犀草素,杨梅宁或其混合物作为活性成分。 神经变性疾病是阿尔茨海默氏病,皮克病,克雅氏综合征,帕金森氏病,卢格里希氏病或亨廷顿舞蹈病。 该组合物抑制BACE-1β-位点APP(淀粉样蛋白前体蛋白)切割酶1],半胱天冬酶或乙酰胆碱酯酶。 该组合物还包含药草。 药用草药是丹参,枸杞子,枸杞子,枸杞子,洋地黄属,荆芥草,竹aci草,虎嘴草,金银花或其混合物。
    • 9. 发明公开
    • 건강기능식품 개발 지원을 위한 플랫폼 시스템
    • 支持卫生功能食品开发的平台系统
    • KR1020130089969A
    • 2013-08-13
    • KR1020120006006
    • 2012-01-19
    • 한국식품연구원
    • 하태열안지윤정창화전태일엄민영권오란김우경정세영이기원김지연김선아
    • G06Q50/04G06Q50/22H04B5/02
    • Y02P90/30G06Q50/04G06Q50/22H04B5/02
    • PURPOSE: A one stop platform system establishes libraries required to develop a functional food by unit technology and provides those having a development demand for functional foods with relevant information in a comprehensive manner. CONSTITUTION: A database (140) contains a first library (210) having information about the functionality of several ingredients of a functional food and a second library (230) having information about the raw materials and manufacturing processes corresponding to each ingredient of the first library. An input/output module communicates with a user device. By using the information of the first library and the second library as well as the relations between the two libraries, a management module selectively provides the user device with the functionality information or the raw material/manufacturing process information of a certain functional food via the input/output module. [Reference numerals] (210) Functional material library; (230) Raw material normalization and manufacturing process library; (250) Functionality evaluation library; (AA) Raw material information; (B1) Function/reference component analysis method (1); (B2) Function/reference component analysis method (2); (B3) Function/reference component analysis method (3); (CC) Processing information; (D1) Extracting process (1); (D2) Extracting process (2); (D3) Powdering process (1); (D4) Powdering process (2); (EE) Material-specific functionality information; (F1) Raw material A; (F10,F15,J2,L5) Functionality B; (F11,F16,J3) Functionality C; (F12,F17) Functionality D; (F13,F18) Functionality E; (F19) Human body applying test document; (F2) Material A1; (F20) Animal test document; (F21) In vitro test document; (F3) Material A2; (F4) Material A3; (F5) Raw material B; (F6) Material B1; (F7) Material B2; (F8) Material B3; (F9,F14,J1,L1) Functionality A; (GG) Material-specific traditional purpose; (H1) Material A; (H2) Material B; (H3) Material C; (H4,H5,H6) Traditional purpose; (II) Functionality screening; (J4,J5,J6,L2,L6) In vitro test; (KK) Functionality evaluation; (L3,L7) In vivo test; (L4,L8) Human body test
    • 目的:一站式平台系统建立了以单位技术开发功能性食品所需的图书馆,并为具有综合性的相关信息功能食品开发需求提供了依据。 构成:数据库(140)包含第一库(210),其具有关于功能食品的若干成分的功能的信息,以及第二库(230),其具有关于与第一库的每个成分对应的原材料和制造过程的信息 。 输入/输出模块与用户设备进行通信。 通过使用第一库和第二库的信息以及两个库之间的关系,管理模块通过输入有选择地向用户设备提供功能信息或特定功能食品的原材料/制造过程信息 /输出模块。 (附图标记)(210)功能材料库; (230)原料标准化与制造过程库; (250)功能评估库; (AA)原材料信息; (B1)功能/参考成分分析方法(1); (B2)功能/参考分量分析方法(2); (B3)功能/参考分量分析方法(3); (CC)处理信息; (D1)提取工序(1); (D2)提取过程(2); (D3)粉化工序(1); (D4)粉化工序(2); (EE)材料特定功能信息; (F1)原料A; (F10,F15,J2,L5)功能B; (F11,F16,J3)功能C; (F12,F17)功能D; (F13,F18)功能E; (F19)人体应用测试文件; (F2)材料A1; (F20)动物试验文件; (F21)体外试验文件; (F3)材料A2; (F4)材料A3; (F5)原料B; (F6)材料B1; (F7)材料B2; (F8)材料B3; (F9,F14,J1,L1)功能A; (GG)物质专用传统用途; (H1)材料A; (H2)材料B; (H3)材料C; (H4,H5,H6)传统用途; (二)功能筛选; (J4,J5,J6,L2,L6)体外试验; (KK)功能评估; (L3,L7)体内试验; (L4,L8)人体试验