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    • 4. 发明授权
    • 생강에서 분리된 쇼가올을 포함하는 비만의 예방 및 치료용조성물
    • 생강에서분리된가가올을포함하는비만의예방및치료용조성물
    • KR100588469B1
    • 2006-11-23
    • KR1020050014031
    • 2005-02-21
    • 한국생명공학연구원
    • 전효곤이호재고영희강수경장규태양재영
    • A61K31/12A61K36/9068A61P3/04A61K31/085
    • A composition for prevention and treatment of obesity comprising shogaol isolated from Zingiber officinale is provided to inhibit formation of adipocytes by inhibiting adipogenesis through which pre-adipocytes are differentiated into adipocytes, and promote release of neutral fats in adipocytes by decomposing triglyceride into free fatty acids and glycerol without side effects. The composition for prevention and treatment of obesity comprises shogaol represented by the formula(1) as an effective ingredient, wherein the shogaol is isolated from Zingiber officinale; the amount of shogaol is 0.01-100 wt.% based on the total weight of the composition; the dosage of shogaol is 0.1-100 mg/kg; and the composition is formulated as food.
    • 本发明提供了一种包含姜生姜醇分离物的肥胖症预防和治疗用组合物,其通过抑制脂肪细胞分化成脂肪细胞的脂肪形成而抑制脂肪细胞的形成,并通过将甘油三酯分解成游离脂肪酸而促进脂肪细胞中的中性脂肪的释放, 甘油无副作用。 所述肥胖症的预防和治疗用组合物包含式(1)所示的姜烯醇作为有效成分,其中姜醇是从姜生姜中分离的; 基于组合物的总重量,姜烯酚的量为0.01-100重量%; 姜烯醇的用量为0.1-100mg / kg; 并且该组合物被配制为食物。