专利快速检索-快速检索全球专利，免费商用专利数据库-IPRDB

1. 发明公开

KR1020100000387A 뼈 형성 촉진 기능을 가지는 퍼모파민 유도체를 함유한조성물 有权
标题翻译：复合物用于促进骨形成的嘌呤衍生物
公开(公告)号：KR1020100000387A
公开(公告)日：2010-01-06
申请号：KR1020080059867
申请日：2008-06-24
申请人： 한경대학교 산학협력단
发明人： 최중국 , 이학교
IPC分类号： C07D473/32 , C07D473/00
摘要： PURPOSE: A composition containing purmorphamine derivative for promoting osteogenesis is provided to increase the rate of osteogenesis and use as basic therapeutic agent. CONSTITUTION: A purmorphamine derivative which activates the expression of gene for a protein regulating osteogenesis and has a function of promoting osteogenesis is denoted by chemical formula 1. The protein contains Runx2, DLX3, alkaline phsphatase and Gli3. A composition for promoting osteogenesis contains the purmorphamine derivative of chemical formula 1 or its salt as an active ingredient. A therapeutic agent for osteoporosis contains the purmorphamine derivative of chemical formula 1 or its salt as an active ingredient.
摘要翻译：目的：提供含有用于促进骨形成的衍生物衍生物的组合物，以增加成骨的速率并用作碱性治疗剂。构成：化学式1表示激活蛋白质调节成骨的基因表达并具有促进成骨功能的嘌呤霉素衍生物。蛋白质含有Runx2，DLX3，碱性磷酸酶和Gli3。用于促进成骨的组合物含有化学式1的吡喃葡萄糖衍生物或其盐作为活性成分。用于骨质疏松症的治疗剂包含化学式1或其盐作为活性成分的异恶唑胺衍生物。

2. 发明公开

KR1020130109886A 상산근 발효 추출물을 포함하는 미백 및 보습 기능성 조성물 및 그 제조방법 无效
标题翻译：含有长沙发酵提取物的皮肤刺激和滋润作用的组合物及其制备方法
公开(公告)号：KR1020130109886A
公开(公告)日：2013-10-08
申请号：KR1020120032006
申请日：2012-03-28
申请人： 한경대학교 산학협력단
发明人： 이학교 , 최중국 , 여창열
IPC分类号： A61K8/97 , A61K36/185 , A61Q19/02 , A61P17/00
摘要： PURPOSE: A functional composition containing a fermented Dichroa febrifuga root extract and a method for manufacturing the same are provided to obtain soap with whitening and moisturizing effects using plant-derived natural products. CONSTITUTION: A functional composition for whitening and moisturizing effects contains a fermented Dichroa febrifuga extract. The composition is manufactured in various types of external use formulations such as liquid and solid soap, a cosmetic product, and an ointment. A method for manufacturing the composition comprises the steps of: extracting Dichroa febrifuga roots and preparing a Dichroa febrifuga root extract; fermenting the extract; and mixing the fermented extract and raw materials. [Reference numerals] (AA) Result of sensory evaluation on composition with whitening and moisturizing function (25 dermatology patients were asked); (BB) Unit: %; (CC) Detergency; (DD) Moisturizing degree; (EE) Skin pull; (FF) Foam; (GG) Whitening effect; (HH) Skin trouble improved; (II) Very good; (JJ) Good; (KK) Fair; (LL) Bad; (MM) Very bad; (NN) Have no idea
摘要翻译：目的：提供含有发酵的二氯菊酯根提取物的功能组合物及其制造方法，以使用植物衍生的天然产物获得具有增白和保湿作用的皂。构成：美白和保湿作用的功能组合物含有发酵的二氯菊酯提取物。该组合物以各种类型的外用制剂如液体和固体肥皂，化妆品和软膏制成。一种制备该组合物的方法，包括以下步骤：提取二倍体赤霉根并制备二氯菊酯根提取物; 发酵提取物; 并混合发酵提取物和原料。（附图标记）（AA）具有增白和保湿功能的组合物的感官评价结果（25名皮肤病患者被询问）; （BB）单位：％; （CC）洗涤剂; （DD）保湿度; （EE）皮拉; （FF）泡沫; （GG）美白效果; （HH）皮肤麻烦改善; （二）很好（JJ）好（KK）公平; （LL）坏（MM）很差（NN）不知道

3. 发明公开

KR1020130109882A 상산근 발효 추출물을 포함하는 아토피성 피부염의 예방 및 치료용 조성물 및 그 제조방법 无效
标题翻译：用于预防或治疗含有长沙的发酵提取物的原生质体及其制备方法的组合物
公开(公告)号：KR1020130109882A
公开(公告)日：2013-10-08
申请号：KR1020120032002
申请日：2012-03-28
申请人： 한경대학교 산학협력단
发明人： 이학교 , 최중국 , 여창열
IPC分类号： A61K36/185 , A61P17/00
摘要： PURPOSE: A composition containing a fermented Dichroa febrifuga root extract and a method for manufacturing the same are provided to prevent and treat atopic dermatitis without side effects to endocrine system and immune system. CONSTITUTION: A composition for preventing and treating atopic dermatitis contains a fermented Dichroa febrifuga root extract. The composition is manufactured in various types of external use formulations such as liquid and solid soap, a cosmetic product, and an ointment. A method for manufacturing the composition comprises the steps of: extracting Dichroa febrifuga roots; fermenting the prepared extract; and mixing the fermented extract with raw materials. [Reference numerals] (AA) Result of sensory evaluation on composition for preventing and treating atopic dermatitis (25 dermatology patients were asked); (BB) Unit : %; (CC) Moisturizing degree; (DD) Sin trouble improved; (EE) Atopic trouble improved; (FF) Itching improved; (GG) Infection eased; (HH) Very goof; (II) Goof; (JJ) Fair; (KK) Bad; (LL) Very bad; (MM) Have no idea
摘要翻译：目的：提供含有发酵的二氯菊酯根提取物的组合物及其制造方法，用于预防和治疗特应性皮炎，对内分泌系统和免疫系统无副作用。构成：用于预防和治疗特应性皮炎的组合物含有发酵的Dichroa febrifuga根提取物。该组合物以各种类型的外用制剂如液体和固体肥皂，化妆品和软膏制成。一种制备该组合物的方法，包括以下步骤：提取二氯菊酯根; 发酵制备的提取物; 并将发酵的提取物与原料混合。（附图标记）（AA）特应性皮炎预防和治疗组合物的感官评价结果（25名皮肤科患者被询问）; （BB）单位：％; （CC）保湿度; （DD）罪恶改善; （EE）特应性麻烦改善; （FF）改善瘙痒; （GG）感染缓解; （HH）Very goof; （二）Goof; （JJ）公平; （KK）坏（LL）很差（MM）不知道

4. 发明授权

KR101020005B1 뼈 형성 촉진 기능을 가지는 퍼모파민 유도체를 함유한조성물 有权
标题翻译：含有促甲状腺素衍生物的复合物用于促进骨形成
公开(公告)号：KR101020005B1
公开(公告)日：2011-03-09
申请号：KR1020080059867
申请日：2008-06-24
申请人： 한경대학교 산학협력단
发明人： 최중국 , 이학교
IPC分类号： C07D473/32 , C07D473/00
摘要： 본 발명은 퍼모파민(Purmorphamine) 유도체의 알칼리성 포스파타제( Alkaine Phosphatase), Runx2, DLX3, Gli3 등의 유전자 발현 유도에 대한 우수한 활성을 규명함으로써, 상기 퍼모파민(Purmorphamine) 유도체를 유효성분으로 함유하는 골형성 촉진용 조성물 및 골다공증 치료제에 관한 것이다.
본 발명의 퍼모파민(Purmorphamine) 유도체는 뼈의 생성 자체를 촉진하는 작용이 있으므로 이를 유효성분으로 함유한 조성물은 골다공증과 같은 골 밀도 저하로 인한 뼈 관련 질환에 대한 근본적인 치료제로 사용할 수 있을 것이다.
조골모세포 분화, BMP 싸이토카인, 뼈 형성, 골다공증 치료제, 퍼모파민 유도체, 알칼리성 포스파타제, Runx2, Gli3

5. 发明公开

KR1020120131681A 게르마늄 광천수 천연비누 无效
标题翻译：天然肥皂由锗矿泉水制成
公开(公告)号：KR1020120131681A
公开(公告)日：2012-12-05
申请号：KR1020110050028
申请日：2011-05-26
申请人： 한경대학교 산학협력단
发明人： 이학교 , 정병호 , 최중국 , 김종정
IPC分类号： C11D9/06 , C11D3/48 , C11D13/18 , C11D13/16
CPC分类号： C11D9/06 , C11D3/48 , C11D13/16 , C11D13/18
摘要： PURPOSE: A natural soap made of germanium mineral water is provided to have sterilizing and anti-inflammatory effects by the function of germanium mineral water which is added during the manufacturing process of a soap. CONSTITUTION: A natural soap made of germanium mineral water is manufactured by a step of mixing a soap base, germanium water, olive oil, jojoba oil, brown rice oil, and perfume in a mixture; a step of compressing a soap paste mixed through the first step; a step of extruding a soap raw material compressed in the second step to a cylindrical shape by using a metal tube; a step of molding the cylindrical soap paste in a die; and a step of measuring the molded soap at a room temperature. [Reference numerals] (ST1) Raw material mixing step; (ST2) Compressing step; (ST3) Extruding step; (ST4) Molding step; (ST5) Measuring step
摘要翻译：目的：提供由锗矿泉水制成的天然肥皂，通过在肥皂制造过程中添加的锗矿泉水的功能具有消毒和抗炎作用。构成：由锗矿泉水制成的天然肥皂通过将皂基，锗水，橄榄油，霍霍巴油，糙米油和香料混合在一起的步骤制造; 压缩通过第一步混合的皂浆的步骤; 通过使用金属管将在第二步骤中压缩的肥皂原料挤压成圆柱形的步骤; 将圆筒形肥皂糊模塑在模具中的步骤; 以及在室温下测量成型皂的步骤。（标号）（ST1）原料混合工序; （ST2）压缩步骤; （ST3）挤压步骤; （ST4）成型步骤; （ST5）测量步骤

6. 发明授权

KR101079140B1 나프토퀴논 유도체 및 그 제조방법 失效
标题翻译：萘醌衍生物及其制备方法
公开(公告)号：KR101079140B1
公开(公告)日：2011-11-02
申请号：KR1020090037570
申请日：2009-04-29
申请人： 한경대학교 산학협력단
发明人： 최중국 , 정용석 , 이학교
IPC分类号： C07C225/30 , A61K31/12 , A61P35/00
摘要： 본발명은나프토퀴논(Naphothoquinone) 유도체및 그제조방법에관한것으로, 보다상세하게는토포아이소머라아제 II(Topoisomerase II)의활성을억제하여암세포의 DNA 복제를손상시키며캐스파아제 3(Caspase 3)를활성화시켜암세포의증식을원천적으로억제시킴으로써백혈병세포의사멸유도및 다양한암의증식억제에유용한나프토퀴논유도체및 그제조방법에관한것이다.

7. 发明公开

KR1020100118736A 나프토퀴논 유도체 및 그 제조방법 失效
标题翻译：萘醌衍生物及其制备方法
公开(公告)号：KR1020100118736A
公开(公告)日：2010-11-08
申请号：KR1020090037570
申请日：2009-04-29
申请人： 한경대학교 산학협력단
发明人： 최중국 , 정용석 , 이학교
IPC分类号： C07C225/30 , A61K31/12 , A61P35/00
摘要： PURPOSE: A naphthoquinone derivative, and a manufacturing method thereof are provided to control the activity of DNA topoisomerase II of cancer cells, and to secure the excellent induction effect of the meronecrosis. CONSTITUTION: A manufacturing method of a naphthoquinone derivative comprises the following steps: producing N-substituted iminomethyl-1,4,5,8-tetramethoxy naphthalene compound, by reacting an oxime compound formed by reacting 2-formyl-1,4,5,8-tetramethoxynaphthalene with hydroxylamine, with iodopropane; oxidizing the outcome with CrO3 or cerium ammonium nitrate, to form 6-alkyliminomethyl-5,8-dimethoxy-1,4-naphthalenedione; and reacting the outcome with AlCl3 or dichloromethane, to form 6-propoxyiminomethyl-5,8-dihydroxy-1,4-naphthalenedione.
摘要翻译：目的：提供一种萘醌衍生物及其制备方法，以控制癌细胞DNA拓扑异构酶II的活性，并确保良好的食管坏死的诱导作用。构成：萘醌衍生物的制造方法包括以下步骤：使2-取代的亚氨基甲基-1,4,5,8-四甲氧基萘化合物通过使2-甲酰基-1,4,5， 8-四甲氧基萘与羟胺，与碘丙烷; 用CrO 3或硝酸铈铵氧化结果，形成6-烷基亚氨基甲基-5,8-二甲氧基-1,4-萘二酮; 并将结果与AlCl 3或二氯甲烷反应，形成6-丙氧基亚氨基甲基-5,8-二羟基-1,4-萘二酮。

你已经成功收藏专利！

检索式保存成功!

IPRDB

热门服务

关于我们

友情链接

联系方式