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1. 发明公开

KR1020120131511A 디플로르에토하이드록시카르마롤 화합물을 유효성분으로 함유하는 간 손상 예방 또는 치료용 조성물 无效
标题翻译：组合物，其包含用于预防或治疗肝损伤的双油酰羟基马来醇
公开(公告)号：KR1020120131511A
公开(公告)日：2012-12-05
申请号：KR1020110049717
申请日：2011-05-25
申请人： 제주대학교 산학협력단 , 재단법인 제주테크노파크
发明人： 신태균 , 현진원 , 안미정 , 양원준 , 강소희 , 고려경 , 김기옥
IPC分类号： A61K31/357 , A61P1/16
摘要： PURPOSE: A composition containing diphlorethohydroxycarmalol extracted from Ishige okamurae is provided to prevent and treat liver injury caused by carbon tetrachloride. CONSTITUTION: A composition for preventing or treating liver injury contains DPHC(diphlorethohydroxycarmalol) of chemical formula 1 or pharmaceutical acceptable salts thereof as an active ingredient. The compound is derived from Ishige okamurae plants. The composition for preventing or treating liver injury contains Ishige okamurae plant extract as an active ingredient. The extract is prepared using water, methanol, ethanol, propanol, isopropanol, butanol, acetone, ether, benzene, chloroform, ethyl acetate, methylene chloride, n-hexane, hydrochloric acid, acetic acid, formic acid, citric acid, diethyl ether, or cyclohexane. A functional food for preventing or treating liver injury contains DPHC or the extract containing the same as an active ingredient.
摘要翻译：目的：提供一种含有从山茱萸提取的双色羟基卡马洛的组合物，用于预防和治疗四氯化碳引起的肝损伤。构成：用于预防或治疗肝损伤的组合物含有化学式1的DPHC（二舒昔洛夫羟基卡马拉）或其药学上可接受的盐作为活性成分。该化合物衍生自Ishige okamurae植物。用于预防或治疗肝损伤的组合物含有植物提取物作为活性成分。提取物用水，甲醇，乙醇，丙醇，异丙醇，丁醇，丙酮，乙醚，苯，氯仿，乙酸乙酯，二氯甲烷，正己烷，盐酸，乙酸，甲酸，柠檬酸，乙醚，或环己烷。用于预防或治疗肝损伤的功能性食品含有DPHC或含有与活性成分相同的提取物。

2. 发明公开

KR1020120015158A 디플로르에토하이드록시카르마롤 화합물을 유효성분으로 함유하는 방사선 방호용 조성물 无效
标题翻译：包含DIPHLORETHOHYDROXYCARMALOL用于辐射防护的组合物
公开(公告)号：KR1020120015158A
公开(公告)日：2012-02-21
申请号：KR1020100077439
申请日：2010-08-11
申请人： 제주대학교 산학협력단 , 재단법인 제주테크노파크
发明人： 신태균 , 현진원 , 주홍구 , 지영흔 , 박재우 , 이남호 , 양원준 , 안미정 , 고려경 , 김기옥
IPC分类号： C07D319/24 , A61K36/03 , A61K31/357 , A61P35/00
摘要： PURPOSE: A radiation protective composition containing diphlorethohydroxycarmalol is provided to suppress cell apoptosis and to enhance hematogenesis and immunity. CONSTITUTION: A radiation protective composition contains DHPC(diphlorethohydroxycarmalol) of chemical formula 1 or pharmaceutically acceptable salt thereof as an active ingredient. The compound is derived from Ishigeaceae plants. The composition also contains Ishigeaceae plant extract as an active ingredient. The Ishigeaceae plant is Ishige okamurae. The extract is prepared using water, methanol, ethanol, propanol, isopropanol, butanol, acetone, ether, benzene, chloroform, ethyl acetate, methylana chloride, n-hexane, acetic acid, formic acid, citric acid, or cyclo hexane.
摘要翻译：目的：提供一种含有双轴羟基卡马洛的辐射防护组合物，以抑制细胞凋亡，增强血液发生和免疫。构成：辐射防护组合物含有化学式1的DHPC（二
色柔和羟基卡马拉）或其药学上可接受的盐作为活性成分。该化合物衍生自石ae科植物。该组合物还含有菊科植物提取物作为活性成分。石斛科植物是Ishige okamurae。萃取液用水，甲醇，乙醇，丙醇，异丙醇，丁醇，丙酮，乙醚，苯，氯仿，乙酸乙酯，甲基丙烯酰氯，正己烷，乙酸，甲酸，柠檬酸或环己烷制备。

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