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    • 2. 发明公开
    • 인삼의 잎과 줄기로부터 생리활성물질을 분획정제하는 방법
    • 金山叶片生理生化活性成分的分离纯化方法
    • KR1020130113717A
    • 2013-10-16
    • KR1020120036127
    • 2012-04-06
    • 재단법인 금산국제인삼약초연구소
    • 표미경유남희김종민유지현김보람이승제박영순홍세철성낙술
    • C07H15/24C07J3/00C07J17/00C08B1/08
    • C07J17/005
    • PURPOSE: A method for fractioning and purifying a physiologically active substance from ginseng leaves and stems is provided to stably obtain expensive ginseng extracts and to show competitive pricing of an ingredient. CONSTITUTION: A method for fractioning and purifying a physiologically active substance from ginseng leaves and stems comprises the steps of: collecting ginseng leaves or stems and naturally drying or freeze-drying the ginseng leaves or stems; pulverizing the dried ginseng leaves and stems to prepare an ingredient; putting the ingredient into an extraction container and adding a solvent in a weight ratio of 1:1.5-3.0; repetitively extracting the ingredient in a water bath with a temperature of 40-60°C using a reflux condenser for 8 hours three times and defatting; collecting the solvent; adding 50-90% ethanol to the ingredient in a ratio of 1:1.5-3.0; extracting the ingredient in a water bath with a temperature of 60-80°C using the reflux condenser for 6-8 hours three times; concentrating the extract; dissolving the extract with 90 % or less methanol (MeOH) in a weight ratio of 1:5-10; injecting the dissolved solution to a separatory funnel and adding n-hexane in a weight ratio of 1:5-10; colleting a methanol layer and concentrating the extract; adding water and water-saturated n-butanol to the concentrate in a weight ratio of 1:5-10; and collecting and concentrating the water-saturated n-butanol.
    • 目的:提取人参叶和茎分泌和纯化生理活性物质的方法,以稳定获得昂贵的人参提取物,并显示成分的有竞争力的价格。 构成:从人参叶和茎分离和纯化生理活性物质的方法包括以下步骤:收集人参叶或茎,并自然干燥或冷冻干燥人参叶或茎; 粉碎干燥的人参叶和茎以制备成分; 将成分加入萃取容器中,加入重量比为1:1.5-3.0的溶剂; 使用回流冷凝器在40-60℃的水浴中重复提取成分8小时三次并脱脂; 收集溶剂; 以1:1.5-3.0的比例向成分中加入50-90%的乙醇; 使用回流冷凝器在60-80℃的水浴中萃取成分6-8小时三次; 浓缩提取物; 用90%或更少的甲醇(MeOH)以1: 5-10的重量比溶解提取物; 将溶解的溶液注入分液漏斗并加入重量比为1: 5-10的正己烷; 收集甲醇层并浓缩提取物; 向浓缩物中加入水和水饱和的正丁醇,重量比为1: 5-10; 并收集并浓缩饱和的正丁醇。
    • 5. 发明公开
    • 인삼 및 뽕나무 추출물을 유효성분으로 함유하는 항당뇨 조성물
    • 含有金山镭和多林提取物作为有效成分的抗糖尿病组合物
    • KR1020140026748A
    • 2014-03-06
    • KR1020120092257
    • 2012-08-23
    • 재단법인 금산국제인삼약초연구소성신비에스티(주)
    • 유지현김상훈이건희표미경성낙술홍세철김보람
    • A61K36/258A61K36/60A61P3/10A61P3/00
    • The present invention relates to an anti-diabetes composition, containing the extracts of ginseng and mulberry tree as active constituents and, more specifically, to an anti-diabetes composition which contains a compound including ginseng, mulberry leaf, mulberry bark, and mulberry syncarp as active constituents. The complex extract includes a mixture of ginseng with mulberry leaf, mulberry bark, and mulberry syncarp in the ratio of 1 : 1 to 30 by weight, or 1 : 2 to 15 by weight, and has a hyperglycemic effect. [Reference numerals] (AA) Composition 1; (BB) Composition 2; (CC) Composition 3; (DD) Composition 4; (EE) Composition 5; (FF) Composition 6; (GG) Composition 7; (HH) Composition 8; (II) Composition 9; (JJ) Composition 10; (KK) Composition 11; (LL) Composition 12; (MM) Composition 13; (NN) Composition 14; (OO) Composition 15; (PP) Composition 16; (QQ) Composition 17; (RR) Composition 18
    • 本发明涉及含有人参和桑树作为活性成分的提取物的抗糖尿病组合物,更具体地,涉及包含人参,桑叶,桑树皮和桑树同化物的化合物的抗糖尿病组合物, 活跃成分。 复合提取物包括以1:1-30重量比或1:2至15重量比的桑参,桑树皮和桑树同系物的混合物,具有高血糖作用。 (附图标记)(AA)组合物1; (BB)组合物2; (CC)组合物3; (DD)组合物4; (EE)组合物5; (FF)组合物6; (GG)组合物7; (HH)组合物8; (二)组合物9; (JJ)组合物10; (KK)组合物11; (LL)组合物12; (MM)组合物13; (NN)组合物14; (OO)组合物15; (PP)组合物16; (QQ)组成17; (RR)组成18