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    • 10. 发明公开
    • 줄기세포 효능 증진제로서의 아그마틴
    • AGMATINE作为干细胞的有效增强剂
    • KR1020110017770A
    • 2011-02-22
    • KR1020090075409
    • 2009-08-14
    • 연세대학교 산학협력단
    • 이종은박경아이원택김재영김재환
    • A61K31/335C12P13/00C12N5/00A61P25/28
    • A61K31/335A61K35/30A61K2300/00
    • PURPOSE: A composition for inducing the differentiation of stem cells containing agmatin or for enhancing stem cell efficiency is provided to promote stem cell differentiation and to protect stem cells. CONSTITUTION: A composition for inducing stem cells contains agmatine as an active ingredient. A composition for enhancing stem cell efficiency contains agmatine as an active ingredient. The stem cells are adult stem cell, such as nerve stem cells, mesenchymal stem cells, skin stem cells, adipose stem cells, olfactory adult stem cells, or dental pulp derived stem cells. A composition for treating central nerve system diseases contains pharmaceutically effective amount of agmatine and nerve stem cells and pharmaceutically acceptable carrier.
    • 目的:提供一种用于诱导含有神经氨酸蛋白的干细胞分化或增强干细胞效率的组合物,以促进干细胞分化并保护干细胞。 构成:用于诱导干细胞的组合物含有丁胺作为活性成分。 用于提高干细胞效率的组合物含有丁胺作为活性成分。 干细胞是成体干细胞,如神经干细胞,间充质干细胞,皮肤干细胞,脂肪干细胞,嗅觉成体干细胞或牙髓干细胞。 用于治疗中枢神经系统疾病的组合物含有药学有效量的胍丁胺和神经干细胞和药学上可接受的载体。