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1. 发明公开

KR1020070059395A 황정 추출물을 유효성분으로 포함하는 면역증강용약학조성물 有权
标题翻译：包含多糖提取物的药物组合物A.增加免疫效果的灰分
公开(公告)号：KR1020070059395A
公开(公告)日：2007-06-12
申请号：KR1020050118198
申请日：2005-12-06
申请人： 대구한의대학교산학협력단
发明人： 김영호 , 양재하 , 강진희 , 전도연 , 김수정 , 한초롱 , 이지영 , 김준석
IPC分类号： A61K36/8969 , A61P37/02
摘要： A pharmaceutical composition for increasing immune effects comprising the extract of Polygonatum falcatum A. Gray is provided to increase production of antibodies against foreign antigens and improve a humoral immune response by promoting migration efficiency of leucocytes from peripheral blood into second immune organs. The pharmaceutical composition for increasing immune effects comprises the extract or purified fraction of Polygonatum falcatum A. Gray, wherein the extract of Polygonatum falcatum A. Gray is prepared by heating the root of Polygonatum falcatum A. Gray in water, and the purified fraction of Polygonatum falcatum A. Gray is prepared by adding acetone into the water extract of Polygonatum falcatum A. Gray to prepare 50% water and acetone mixed solvent and removing the precipitated matters from the solution so as to prepare the supernatant containing acetone-soluble components; adding acetone into the supernatant to prepare 80% water and acetone mixed solvent and recovering the precipitated matters; and dissolving the precipitated matters in distilled water and re-precipitating the solution with 80% acetone. A health food for increasing immune effects comprises the extract or purified fraction of Polygonatum falcatum A. Gray, wherein the health food is formulated as powder, granule, tablet, capsule or drink.
摘要翻译：提供了一种用于增加免疫效果的药物组合物，其中包括提取物黄um提取物A.用于增加针对外来抗原的抗体的产生，并通过促进白细胞从外周血向第二免疫器官的迁移效率来改善体液免疫应答。用于增加免疫效果的药物组合物包括黄芪提取物或纯化的部分，其中通过加热水中的黄芪根和灰分的纯化部分制备黄芪提取物，通过将丙酮加入到黄芪的水提取物中制备灰分，制备50％的水和丙酮混合溶剂，并从溶液中除去沉淀的物质，以制备含丙酮可溶组分的上清液; 向上清液中加入丙酮以制备80％的水和丙酮混合溶剂并回收沉淀的物质; 并将沉淀物溶解在蒸馏水中并用80％丙酮重新沉淀溶液。用于增加免疫效果的保健食品包括茯苓的提取物或纯化部分，其中保健食品配制成粉末，颗粒，片剂，胶囊或饮料。

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