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1. 发明授权

KR100395338B1 크리신 유도체 및 이들을 포함한 혈당강하제용 조성물 失效
标题翻译：圣诞节前夕
公开(公告)号：KR100395338B1
公开(公告)日：2003-08-19
申请号：KR1019990027846
申请日：1999-07-09
申请人： 김박광
发明人： 이상현 , 양성심 , 장지면 , 정춘식 , 신준수 , 최원규 , 김박광
IPC分类号： C07D311/02
摘要： PURPOSE: The chrysin derivatives and a hypoglycemic composition containing the compounds are provided, thereby the novel medicines containing the chrysin composition can be developed for falling blood sugar without side effects. CONSTITUTION: The chrysin is a flavonoid plant having hydroxyl group at C5 and C7 sites and has anti-oxidant, anti-inflammatory, anti-cancer and anti-allergic properties. The chrysin derivatives are represented by formula (1), in which R1 is hydrogen or propyl, R2 is propyl, butyl, octyl or toluic. The hypoglycemic composition contains the chrysin derivatives in an amount of 100 to 1000 mg/day, preferably 200 to 400 mg/day or in an amount of 1/2, 1/3, 1/4, 1/5 or 1/6 of the above amount and may be administrated to a patient suffering from diabetes 1 to six times a day.
摘要翻译：目的：提供白屈菜衍生物和含有这些化合物的降血糖组合物，由此可以开发出含有白杨组合物的新药，用于降血糖而没有副作用。组成：白杨素是在C5和C7位点具有羟基的类黄酮植物，具有抗氧化，抗炎，抗癌和抗过敏性质。白杨素衍生物由式（1）表示，其中R 1是氢或丙基，R 2是丙基，丁基，辛基或甲苯基。所述降血糖组合物含有100至1000mg /天，优选200至400mg /天或量的1 / 2,1 / 3,1 / 4,1 / 5或1/6的量的白杨素衍生物上述量并且可以一天给予患有糖尿病的患者1至6次。

2. 发明公开

KR1020010009475A 크리신 유도체 및 이들을 포함한 혈당강하제용 조성물 失效
标题翻译： CHRYSIN衍生物和含有它的高分子化合物
公开(公告)号：KR1020010009475A
公开(公告)日：2001-02-05
申请号：KR1019990027846
申请日：1999-07-09
申请人： 김박광
发明人： 이상현 , 양성심 , 장지면 , 정춘식 , 신준수 , 최원규 , 김박광
IPC分类号： C07D311/02
摘要： PURPOSE: The chrysin derivatives and a hypoglycemic composition containing the compounds are provided, thereby the novel medicines containing the chrysin composition can be developed for falling blood sugar without side effects. CONSTITUTION: The chrysin is a flavonoid plant having hydroxyl group at C5 and C7 sites and has anti-oxidant, anti-inflammatory, anti-cancer and anti-allergic properties. The chrysin derivatives are represented by formula (1), in which R1 is hydrogen or propyl, R2 is propyl, butyl, octyl or toluic. The hypoglycemic composition contains the chrysin derivatives in an amount of 100 to 1000 mg/day, preferably 200 to 400 mg/day or in an amount of 1/2, 1/3, 1/4, 1/5 or 1/6 of the above amount and may be administrated to a patient suffering from diabetes 1 to six times a day.
摘要翻译：目的：提供含有这些化合物的chrysin衍生物和降血糖组合物，从而可以开发含有chrysin组合物的新型药物用于降血糖而没有副作用。构成：辣椒素是在C5和C7位置具有羟基的类黄酮植物，具有抗氧化，抗炎，抗癌和抗过敏等特性。氯仿衍生物由式（1）表示，其中R 1是氢或丙基，R 2是丙基，丁基，辛基或甲苯基。降血糖组合物含有100至1000mg /天，优选200至400mg /天或以1/2，1 / 3,1 / 4,1 / 5或1/6的量存在的chrysin衍生物以上数量，并且可以每天服用于患有糖尿病的患者1至6次。

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