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81. 发明公开

KR1020080105730A 바이플라보노이드를 함유하는 피부 주름 개선 화장료 有权
标题翻译：用于外用于含有双歧杆菌衍生物的皮肤的抗皱组合物
公开(公告)号：KR1020080105730A
公开(公告)日：2008-12-04
申请号：KR1020070053700
申请日：2007-06-01
申请人： (주)아모레퍼시픽 , 조선대학교산학협력단
发明人： 이찬우 , 김한성 , 최현정 , 김덕희 , 장이섭 , 우은란
IPC分类号： A61K8/49 , A61K8/97 , A61Q19/08
CPC分类号： A61Q19/08 , A61K8/498 , A61K8/97 , A61Q17/04
摘要： A cosmetic composition is provided to improve the skin winkle without the side effect by producing procollagen and by inhibiting MMP-1. A cosmetic composition contains 0.001-10 wt% of a biflavonoid derivative as an active ingredient. Preferably the biflavonoid derivative is extracted from Selaginella tamariscina, Ginkgo biloba, Cephalotaxus koreana, Nandina domestica, and Lonicera japonica. Preferably the biflavonoid derivative is represented by the formulas 1 to 7.
摘要翻译：提供化妆品组合物以通过产生前胶原和通过抑制MMP-1来改善皮肤眨眼而没有副作用。化妆品组合物含有0.001-10重量％的双黄酮衍生物作为活性成分。优选地，从黄单胞菌（Selaginella tamariscina），银杏（Ginkgo biloba），白芍（Cephalotaxus koreana），南极扁桃（Nandina domestica）和忍冬（Lonicera japonica）中提取双黄酮衍生物。优选地，双黄酮衍生物由式1至7表示。

82. 发明公开

KR1020080098808A 타이로시네이즈 저해 활성 및 갈변화 현상 저해 효과를갖는 레조캄페롤을 포함하는 조성물 无效
标题翻译：包含具有酪氨酸酶抑制活性和抗体活性的抗氧化剂的组合物
公开(公告)号：KR1020080098808A
公开(公告)日：2008-11-12
申请号：KR1020070044138
申请日：2007-05-07
申请人： 건국대학교 산학협력단
发明人： 이충환 , 최정남 , 김지영 , 박지연
IPC分类号： A61K8/49 , A61K8/35 , A61Q19/02
CPC分类号： A61K8/498 , A23L3/34 , A61K31/352 , A61K2800/782 , A61Q19/02
摘要： A composition including a resokaempferol is provided to prevent a melanin from being generated by hindering an activity of a tyrosinase, to inhibit a brown coloring of food by preventing the melanin from being generated largely and to improve or prevent fleck and dark circle. A composition for skin whitening for preventing a melanin from being generated comprises a resokaempferol represented by a chemical formula 1 or pharmaceutically allowable salts as an active ingredient. The resokaempferol is manufactured by being obtained from plant or synthesized chemically. A composition for conserving food comprises the resokaempferol represented by the chemical formula 1 or the pharmaceutically allowable salts as an active ingredient.
摘要翻译：提供了一种组合物，其用于通过阻止酪氨酸酶的活性，通过防止黑色素大量生成来抑制食物的褐色，改善或防止斑点和黑眼圈，从而产生黑色素。用于防止产生黑色素的皮肤美白用组合物包含由化学式1表示的雷莫普罗或作为有效成分的药学上允许的盐。通过从植物获得或化学合成制备resokaemferferol。用于保存食物的组合物包含由化学式1表示的雷莫普乐或其药学上可允许的盐作为活性成分。

83. 发明授权

KR100865421B1 레티노이드 및 레티노이드 부스터 시스템을 포함하는안정한 피부 관리 조성물 失效
标题翻译：稳定的皮肤护理组合物包含一种再生剂和一种再生增效剂体系
公开(公告)号：KR100865421B1
公开(公告)日：2008-10-24
申请号：KR1020037008755
申请日：2001-12-06
申请人： 유니레버 엔.브이.
发明人： 그랭거,스트워트패이톤 , 찬다르,프렘 , 스콧트,이안,리차드
IPC分类号： A61K8/67 , A61K8/72 , A61Q19/00
CPC分类号： A61Q19/08 , A61K8/33 , A61K8/34 , A61K8/342 , A61K8/347 , A61K8/35 , A61K8/361 , A61K8/362 , A61K8/365 , A61K8/416 , A61K8/42 , A61K8/44 , A61K8/49 , A61K8/4926 , A61K8/4946 , A61K8/496 , A61K8/498 , A61K8/553 , A61K8/63 , A61K8/671 , A61K8/68 , A61K8/922 , A61Q19/00
摘要： 약 0.0001% 내지 약 50%의 1종 이상의 레티노이드 부스터(booster);약 0.001% 내지 약 10%의 레티노이드; 및 미용학적으로 허용 가능한 부형제를 포함하며, 여기에서 안정한 피부 관리 조성물은 조성물이 산소와 접촉되지 않도록 하는 포장 내에 포함되는 안정한 피부 관리 조성물.

레티노이드, 레티노이드 부스터

84. 发明授权

KR100862957B1 히페린을 유효성분으로 포함하는 피부주름 개선용 조성물 有权
标题翻译：用于改善包含HYPERIN作为活性成分的皮肤皱纹的组合物
公开(公告)号：KR100862957B1
公开(公告)日：2008-10-13
申请号：KR1020070032676
申请日：2007-04-03
申请人： 바이오스펙트럼 주식회사
发明人： 박덕훈 , 정은선 , 이종성
IPC分类号： A61K8/49 , A61Q19/08
CPC分类号： A61K8/498 , A23L33/10 , A61K31/352 , A61K2800/59 , A61Q19/08
摘要： A composition comprising hyperin and taxifolin is provided to increase collagen synthesis, inhibit collagenase activity efficiently, prevent skin wrinkle from being formed and reduce wrinkles with no skin side effects, thereby being safely applied to a cosmetic, a pharmaceutical or a food composition. A composition for improving skin wrinkles comprises 0.0001-20.0 wt.% of hyperin and taxifolin as effective ingredients, wherein the weight ratio of the hyperin and the taxifolin is 1:1. The composition is a cosmetic composition, a pharmaceutical composition or a food composition. Further, the cosmetic composition is a form selected from solution, paste, gel, cream, lotion, soap, surfactant-comprised cleansing, oil, powder foundation, wax foundation and spray.
摘要翻译：提供了含有羟脯氨酸和紫杉酚的组合物，以增加胶原合成，有效抑制胶原酶活性，防止皮肤皱纹形成，减少皱纹，无皮肤副作用，从而安全地应用于化妆品，药物或食品组合物。用于改善皮肤皱纹的组合物包含0.0001-20.0重量％的hyperin和taxifolin作为有效成分，其中hyperin和taxifolin的重量比为1:1。该组合物是化妆品组合物，药物组合物或食物组合物。此外，化妆品组合物是选自溶液，糊剂，凝胶，乳膏，洗剂，皂，含表面活性剂的清洁剂，油，粉底，蜡基和喷雾剂的形式。

85. 发明授权

KR100855146B1 신규한 인다닐리덴 화합물 失效
标题翻译：新型亚茚基化合物
公开(公告)号：KR100855146B1
公开(公告)日：2008-08-28
申请号：KR1020037006348
申请日：2001-10-30
申请人： 짐리즈 게엠베하 운트 캄파니 카게
发明人： 코흐,오스카 , 딜크,에리히 , 랑그너,롤란드 , 존콕,윌리암
IPC分类号： C07C255/40
CPC分类号： C07D319/14 , A61K8/40 , A61K8/498 , A61K8/585 , A61Q17/04 , C07C255/40 , C07C2601/14 , C07C2602/08 , C07F7/0854
摘要： 2-(1-Indanylidene)-3-oxo-alkanoic acid derivatives (I) (including esters, amides and nitriles) are new. Indanylidene compounds of formula (I) are new. R1 - R4 = H, 1-20C alkyl or 5-10C cycloalkyl; or 2-20C alkyl in which at least one CH2 is replaced by O, 3-20C alkenyl, 3-20C alkynyl or S'; or of R1 - R4 on adjacent C may together form optionally substituted 1-4C alkylene; S' = silane, oligosilane or polysiloxane group; R5 - R8 = H, 1-20C alkyl, 5-10C cycloalkyl, 1-20C alkoxy, 5-10C cycloalkoxy, OH, acetoxy, acetamino, COOH, alkoxycarbonyl or carbamoyl; or 2-20C alkyl in which at least one CH2 is replaced by O, 3-20C alkenyl, 3-20C alkynyl or S'; or two of R5 - R8 on adjacent C may together form a 5-7 membered ring containing up to 3 heteroatoms (specifically O or N) and optionally substituted by exocyclic =O (keto); X = CN, CON(R)2 or COOR; R = H or 1-4C alkyl; n = 0 or 1. If n is1 then R9 - R11 = H, 1-20C alkyl, 5-10C cycloalkyl, aryl or heteroaryl; or two of R9 - R11 together form a 3-7 membered ring optionally containing up to 3 heteroatoms (specifically O or N); if n is 0 then CR9R10 = aryl or heteroaryl.

86. 发明公开

KR1020080067386A 이중 구획 포장 내에 레티노이드, 레티노이드 부스터 및피토에스트로겐을 포함하는 피부 관리 제품 无效
标题翻译：皮肤护理产品在双层包装中含有再生物，除虫剂和生物素
公开(公告)号：KR1020080067386A
公开(公告)日：2008-07-18
申请号：KR1020087015959
申请日：2001-12-06
申请人： 유니레버 엔.브이.
发明人： 필레,스리쿠마 , 그랭거,스트워트패이톤 , 스콧트,이안,리차드 , 포칼리코,데이빗,조세프
IPC分类号： A61K8/67 , A61K8/72 , A61K8/63 , A61Q19/00
CPC分类号： A61Q19/08 , A61K8/02 , A61K8/342 , A61K8/345 , A61K8/35 , A61K8/42 , A61K8/442 , A61K8/4946 , A61K8/498 , A61K8/63 , A61K8/671 , A61K8/922 , A61K8/97 , A61K31/07 , A61K2800/52 , A61K2800/70 , A61K2800/88 , A61Q19/00 , A61Q19/007 , A61Q19/02 , A61K2300/00
摘要： A stable skin care product containing a first composition comprising about 0.001 % to about 10 % of a retinoid; a second composition comprising about 0.0001 % to about 50 % of at least one retinoid booster and about 0.001 % to about 10 % of a phytoestrogen; a first compartment for storing the first composition; and a second compartment for storing the second composition, the first and second compartments being joined together.
摘要翻译：一种稳定的护肤品，其含有包含约0.001％至约10％类视黄醇的第一组合物; 包含约0.0001％至约50％的至少一种类视黄醇助推器和约0.001％至约10％的植物雌激素的第二组合物; 用于存储第一组合物的第一隔室; 以及用于存储第二组合物的第二隔室，第一和第二隔室连接在一起。

87. 发明公开

KR1020080063731A 구강 위생 증진용 조성물 无效
标题翻译：口腔护理组合物
公开(公告)号：KR1020080063731A
公开(公告)日：2008-07-07
申请号：KR1020080049859
申请日：2008-05-28
申请人： 주식회사 엘지생활건강
发明人： 최종헌 , 강택균 , 장은경 , 안재현 , 김영호 , 김문무
IPC分类号： A61K8/34 , A61K8/97 , A61Q11/00
CPC分类号： A61K8/347 , A61K8/19 , A61K8/498 , A61Q11/00 , Y10S514/901
摘要： A composition for enhancing the hygiene of the mouth is provided to maximize delivery and remaining of triclosan by comprising bamboo salt with periodental diseases prophylactic effect and dipotassium glycyrrhizinate, thereby promoting anti-bacterial effect, plague formation inhibitory effect and gingivitis alleviating effect. A composition for enhancing the hygiene of the mouth by improving absorption of triclosan into oral cavity comprises 0.10-30 wt.% of bamboo salt, 0.0001-1.0 wt.% of triclosan and 0.005-1.00 wt.% of dipotassium glycyrrhizinate.
摘要翻译：提供了一种提高口腔卫生的组合物，通过包含竹盐与周期性疾病预防效果和甘草酸二钾的最大化输送和保留三氯生，从而促进抗菌作用，瘟疫形成抑制作用和牙龈炎缓解作用。通过改善三氯生对口腔的吸收来提高口腔卫生的组合物包括0.10-30重量％的竹盐，0.0001-1.0重量％的三氯生和0.005-1.00重量％的甘草酸二钾。

88. 发明公开

KR1020080055984A 인산화당을 함유한 피부외용제 有权
标题翻译：含有磷酸盐的皮肤的外用制剂
公开(公告)号：KR1020080055984A
公开(公告)日：2008-06-19
申请号：KR1020087010744
申请日：2006-09-13
申请人： 에자끼구리고가부시키가이샤
发明人： 다나카도모코 , 가마사카히로시 , 스기모토가즈히사 , 니시무라다카히사 , 구리키다카시
IPC分类号： A61K8/60 , A61Q5/00 , A61Q19/00
CPC分类号： A61K8/73 , A61K8/498 , A61K8/60 , A61Q17/04 , A61Q19/007 , A61Q19/02 , A61Q19/08 , A61Q19/10
摘要： Disclosed is a pharmaceutical preparation for external application to the skin, which comprises a phosphorylated sugar. The phosphorylated sugar may be an inorganic salt of a phosphorylated sugar. The phosphorylated sugar may be in the form of a calcium salt, a magnesium salt, a potassium salt, a zinc salt, an iron salt or a sodium salt. Also disclosed is a pharmaceutical preparation for external application to the skin, which comprises a phosphorylated sugar and a second component. The second component is selected from the group consisting of a moisturizing component, a skin-whitening agent, an UV-absorber, an anti-inflammatory agent, a cell-activating agent and an anti-oxidant. The moisturizing agent may be ascorbic acid or an ascorbic acid derivative.
摘要翻译：公开了一种外用于皮肤的药物制剂，其包含磷酸化糖。磷酸化糖可以是磷酸化糖的无机盐。磷酸化糖可以是钙盐，镁盐，钾盐，锌盐，铁盐或钠盐的形式。还公开了外用于皮肤的药物制剂，其包含磷酸化糖和第二成分。第二组分选自保湿组分，皮肤增白剂，紫外线吸收剂，抗炎剂，细胞活化剂和抗氧化剂。保湿剂可以是抗坏血酸或抗坏血酸衍生物。

89. 发明授权

KR100819173B1 장기간 안정적으로 비타민 씨를 적용할 수 있는 화장품조성물 有权
标题翻译：包含维生素C的化妆品组合物
公开(公告)号：KR100819173B1
公开(公告)日：2008-04-03
申请号：KR1020070089643
申请日：2007-09-04
申请人： 주식회사 콧데 , 이재홍
发明人： 장동일 , 정윤주 , 이재홍
IPC分类号： A61K8/67 , A61Q19/00
CPC分类号： A61K8/365 , A61K8/02 , A61K8/498 , A61K8/671 , A61K8/676 , A61K8/97 , A61K2800/522 , A61K2800/88 , A61K2800/882 , A61Q19/02 , A61Q19/08
摘要： A cosmetic composition comprising vitamin C is provided to preserve the vitamin C for 3 years or more by keeping the vitamin C in a solid form from a liquid if there is no artificial temperature increase, strong transmission of light and supply of oxygen and also maintain the vitamin C stable for at least 6 months when in use by being mixed with the liquid. In a cosmetic composition including a solid containing vitamin C and a liquid phase separately to mix them right before use, the solid further comprises at least one antioxidizing agent selected from the group consisting of kojic acid, alpha-lipoic acid, proanthocyanidin, retinol, a retinol derivative, co-enzyme Q10, a cysteine-based antioxidizing agent, selenium, pycnogenol, enzogenol and fingenol and carbonate is dissolved in demineralized water or de-ionized water to decrease dissolved oxygen in the liquid phase. The composition further comprises at least one selected from the group consisting of a moisturizer, a surfactant, a thickener, a pH adjusting agent and a sequestering agent.
摘要翻译：提供包含维生素C的化妆品组合物，以通过将维生素C从液体中保持固体形式而保持维生素C 3年或更长时间，如果没有人为的温度升高，光的透过和氧气的供应，并且还维持维生素C在与液体混合使用时稳定至少6个月。在包含含有维生素C和液相的固体的化妆品组合物中，分别在使用前将其混合，所述固体还包含至少一种抗氧化剂，其选自曲酸，α-硫辛酸，原花色素，视黄醇，视黄醇衍生物，辅酶Q10，基于半胱氨酸的抗氧化剂，硒，碧萝芷，恩替加酚和指甲酚和碳酸盐溶解在软化水或去离子水中以降低液相中的溶解氧。组合物还包含选自保湿剂，表面活性剂，增稠剂，pH调节剂和螯合剂中的至少一种。

90. 发明公开

KR1020080027281A 아이소플라본의 나노입자를 포함하는 국소용 조성물 失效
标题翻译：包含ISOFLAVONE的纳米颗粒的主题组合物
公开(公告)号：KR1020080027281A
公开(公告)日：2008-03-26
申请号：KR1020077030504
申请日：2006-01-31
申请人： 디에스엠 아이피 어셋츠 비.브이.
发明人： 보이머라파엘 , 첸차이-쳉 , 구츠빌러하인즈 , 메일란필리뻬엠마뉴엘 , 노보트니마르쿠스 , 슐레겔베른트 , 볼하르드트유르겐에이치
IPC分类号： B82B3/00
CPC分类号： A61Q19/00 , A61K8/0241 , A61K8/347 , A61K8/498 , A61K8/732 , A61K9/0014 , A61K9/145 , A61K9/1694 , A61K31/352 , A61K2800/413 , A61Q17/005 , A61Q17/04 , A61Q19/02 , A61Q19/08 , B82Y5/00 , Y10S977/926
摘要： The present invention is directed to topical compositions, comprising isoflavone nanoparticle compositions. The isoflavone nanoparticle compositions contain isoflavone in the form of nanoparticles and preferably a carrier. In the topical compositions recrystallization of the isoflavone to bigger particles is avoided. ® KIPO & WIPO 2008
摘要翻译：本发明涉及包含异黄酮纳米颗粒组合物的局部组合物。异黄酮纳米颗粒组合物含有纳米颗粒和优选载体形式的异黄酮。在局部组合物中，避免了将异黄酮重结晶成更大的颗粒。 ®KIPO＆WIPO 2008

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