专利快速检索-快速检索全球专利，免费商用专利数据库-IPRDB

81. 发明公开

KR1020000053006A 경피 약제 플럭스를 향상시키기 위한 장치 및 방법 失效
标题翻译：用于增强变形剂流体的装置和方法
公开(公告)号：KR1020000053006A
公开(公告)日：2000-08-25
申请号：KR1019997003888
申请日：1997-12-16
申请人： 앨자 코포레이션
发明人： 디유스펠릭스 , 노이커만스아만드피. , 코미어미첼제이.엔.
IPC分类号： A61M37/00
CPC分类号： A61K9/0021 , A61B17/205 , A61B2010/008 , A61M37/00 , A61M2037/0007 , A61N1/306
摘要： PURPOSE: A transdermal delivery of agents, is provided which is such as peptides and proteins, through the skin of an animal, as well as the transdermal sampling of agents, such as glucose, electrolyte and substances of abuse, such as but not limited to alcohol and illicit drugs. CONSTITUTION: A high volume is producable, low-cost device suitable for increasing transdermal flux with skin piercing protrusions and contacting a body surface over a large contact area to reduce skin irritation and enhance agent delivery or sampling. The device of the present invention pierces the stratum corneum of a body surface to form pathways through which a substance can either be introduced (i.e., delivery) or withdrawn (i.e., sampling). In one aspect, the invention comprises a plurality of protrusions for piercing the skin which extend through a connecting medium. The connecting medium assists in making substantial contact with the body surface for either delivering or sampling an agent. For an electrotransport device, the connecting medium spreads out the contact area to all the protrusions to reduce the current density at particular locations to reduce irritation.
摘要翻译：目的：提供试剂的透皮递送，例如肽和蛋白质，通过动物的皮肤，以及试剂（例如葡萄糖，电解质和滥用物质）的透皮取样，例如但不限于酒精和非法药物。构成：大体积是可生产的，低成本的装置，适用于通过皮肤穿刺突起增加透皮通量，并在大的接触区域接触体表，以减少皮肤刺激并增强药剂输送或取样。本发明的装置刺穿身体表面的角质层以形成通过其可以引入（即递送）或撤回（即取样）物质的途径。一方面，本发明包括多个突起，用于刺穿穿过连接介质的皮肤。连接介质有助于与身体表面实质接触，用于递送或取样试剂。对于电输送装置，连接介质将接触区域扩展到所有突起，以减小特定位置处的电流密度，以减少刺激。

82. 发明公开

KR1020000016698A 경피샘플링을향상시키는장치및방법 失效
标题翻译：用于增强超声波采样的装置
公开(公告)号：KR1020000016698A
公开(公告)日：2000-03-25
申请号：KR1019980710301
申请日：1997-06-18
申请人： 알자 코포레이션
发明人： 코미어마이클제이엔 , 디우웨스펠릭스티
IPC分类号： A61N1/30
CPC分类号： A61M37/0015 , A61B5/14514 , A61B5/150022 , A61B5/150099 , A61B5/150282 , A61B5/150427 , A61B5/150969 , A61B5/150984 , A61B5/15105 , A61B5/15113 , A61B5/15142 , A61B10/0045 , A61B17/205 , A61M2037/0007 , A61M2037/0023 , A61M2037/0038 , A61M2037/0046 , A61M2037/0053 , A61N1/30 , A61N1/303
摘要： PURPOSE: Disclosed is a device for piercing the stratum corneum of a body surface to form pathways through which an agent can be withdrawn. CONSTITUTION: The device (10, 88, 98, 104) for piercing the stratum corneum of a body surface to form pathways through which an agent can be withdrawn. The device comprises:a sheet (6) having a plurality of micro blades (4) extending downward therefrom for piercing the stratum corneum, and a collector (26, 90, 106) on the sheet (6) which withdraws the agent through the pathways.
摘要翻译：目的：公开了一种用于刺穿身体表面的角质层以形成可以撤回药剂的途径的装置。构成：用于刺穿身体表面的角质层的装置（10,88,98,104），以形成可以撤回药剂的通路。该装置包括：具有从其向下延伸以刺穿角质层的多个微型叶片（4）的片材（6），以及片材（6）上的收集器（26,90,106），其将药剂通过路径。

83. 发明公开

KR1020000016697A 경피제제의투여또는샘플링을향상시키는장치 失效
标题翻译：用于增强转基因药物递送或采样的装置
公开(公告)号：KR1020000016697A
公开(公告)日：2000-03-25
申请号：KR1019980710300
申请日：1997-06-18
申请人： 알자 코포레이션
发明人： 코미어마이클제이엔 , 누커만스아만드피 , 블럭배리 , 낫에브타에스
IPC分类号： A61N1/30
CPC分类号： A61M37/0015 , A61B5/14514 , A61B5/150022 , A61B5/150099 , A61B5/150282 , A61B5/150427 , A61B5/150969 , A61B5/150984 , A61B5/15105 , A61B5/15113 , A61B5/15142 , A61B10/0045 , A61B17/205 , A61M2037/0007 , A61M2037/0023 , A61M2037/0038 , A61M2037/0046 , A61M2037/0053 , A61N1/30 , A61N1/303
摘要： PURPOSE: A percutaneous agent delivery or sampling device for piercing the skin for increasing transdermal flux of an agent is provided. CONSTITUTION: The percutaneous agent delivery or sampling device (10) comprising a sheet (6) having at least one opening (8) there through and a plurality of micro blades (4) for piercing the skin for increasing transdermal flux of an agent. The micro blades (4) having a relatively sharp angled leading edge (11, 11') which transitions to a relatively gradually angled blade edge (13, 13').
摘要翻译：目的：提供一种用于穿刺皮肤以增加药剂经皮通量的经皮剂递送或取样装置。构成：经皮剂递送或取样装置（10）包括其上具有至少一个开口（8）的片材（6）和用于刺穿皮肤以增加药剂经皮通量的多个微型刀片（4）。微型叶片（4）具有相对尖锐的倾斜的前缘（11,11'），其转变成相对逐渐倾斜的叶片边缘（13,13'）。

你已经成功收藏专利！

检索式保存成功!

IPRDB

热门服务

关于我们

友情链接

联系方式