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    • 51. 发明公开
    • 마스크 기재용 하이드로겔 조성물 및 이를 이용한 하이드로겔의 제조방법
    • 用于保存物体的水凝胶组合物和使用其制备氢化物的方法
    • KR1020130036543A
    • 2013-04-12
    • KR1020110100690
    • 2011-10-04
    • 주식회사 제닉
    • 유현오김종철양진아최은경임재민
    • C08L33/04C08L25/04C08L5/00C08K5/05
    • C08L39/06A61K8/0212A61K8/042A61K8/342A61K8/345A61K8/73A61K8/733A61K8/737A61K8/8117A61K8/8152A61K8/8182A61K2800/244A61Q19/00C08J3/075C08J3/246C08J5/18C08J2305/00C08J2325/08C08J2325/14C08J2333/02C08J2333/08C08J2339/06C08L25/08C08L25/14C08L33/08C08L2201/54C08L2312/00C08L5/00
    • PURPOSE: A hydrogel composition for a holding object is provided to maintain the shape without a support and maintaining stable properties when impregnating the composition into a drug material. CONSTITUTION: A hydrogel composition for holding a mask substrate comprises 0.1-10 weight% of a crosslinking agent, 0.2-6 weight% of a gelated polymer, 0.5-20 weight% of a polyhydric alcohol, and 70-90 weight% of purified water. The crosslinking agent is an acrylic cross-linked polymer or a mixture thereof. The mixture of the cross-linked polymer and the styrene-based copolymer is added with a weight ratio of 2:8-8:2. The gelated polymer is one or more selected from galactomannan, glucomannan, guar gum, Locust bean gum, pluronic, agar, algin, carrageenan, xanthan gum, and gellan. [Reference numerals] (S110) Step of manufacturing an aqueous solution by adding a crosslinking agent in refined water at room temperature and stirring at high temperatures; (S120) Step of manufacturing a hydrogel composition by adding gelated polymer in polyhydric alcohol at room temperature to be dissolved and introducing into the aqueous solution; (S130) Step of compressively coating the hydrogel composition; (S140) Step of manufacturing hydrogel by cooling the compressively coated hydrogel composition at room temperature; (S150) Step of thermally treating the cooled hydrogel;
    • 目的:提供用于保持物体的水凝胶组合物以在不含支持物的情况下保持形状,并且当将组合物浸渍到药物材料中时保持稳定的性质。 构成:用于保持掩模底物的水凝胶组合物包含0.1-10重量%的交联剂,0.2-6重量%的凝胶化聚合物,0.5-20重量%的多元醇和70-90重量%的净化水 。 交联剂是丙烯酸交联聚合物或其混合物。 加入交联聚合物和苯乙烯基共聚物的混合物,重量比为2:8-8:2。 凝胶化聚合物是选自半乳甘露聚糖,葡甘露聚糖,瓜尔胶,刺槐豆胶,普鲁尼酮,琼脂,藻酸,角叉菜胶,黄原胶和结冷胶中的一种或多种。 (S110)在室温下在精制水中加入交联剂并在高温搅拌下制造水溶液的步骤; (S120)通过在室温下将凝胶化聚合物加入到多元醇中来制造水凝胶组合物的步骤,以溶解并引入到水溶液中; (S130)水凝胶组合物的压缩性涂布工序; (S140)通过在室温下冷却压缩涂布的水凝胶组合物来制造水凝胶的步骤; (S150)冷却水凝胶的热处理工序;