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    • 55. 发明公开
    • 태반 추출물을 유효성분으로 함유하는 빈혈질환 치료 또는 예방용 조성물
    • 用于治疗或预防麻醉的组合物
    • KR1020120074650A
    • 2012-07-06
    • KR1020100136551
    • 2010-12-28
    • 영남대학교 산학협력단
    • 최인호이동목이은주이기호전용필전태훈
    • A61K35/50A61K31/56A61K31/568A61K31/565A61K31/566A23L1/30
    • A61K35/50A23L33/10A61K31/56A61K31/565A61K31/566A61K31/568
    • PURPOSE: A composition containing placental extracts is provided to increase the proliferation of hematopoietic stem cells, to enhance hemoglobin amount, and to treat anemia. CONSTITUTION: A method for preparing placental extract comprises: a step of homogenizing placenta with an extraction solvent; a step of filtering the homogenized materials to remove residue; a step of adding water to the filtrate and separating the mixture into a lower layer and supernatant; a step of volatilizing organic solvent from the lower layer; a step of adding an alcohol solution to the remaining solution; a step of adding an alkali solution and then heating in a water bath; a step of adjusting pH with an acid solution; a step of adding ether, mixing, and separating the mixture into layers; and a step of collecting and purifying an ether layer. The placental extract contains nandrolone, testosterone, estradiol, and estrone. A pharmaceutical composition for preventing or treating anemia contains the placental extract as an active ingredient.
    • 目的:提供含有胎盘提取物的组合物,以增加造血干细胞的增殖,提高血红蛋白量,并治疗贫血。 构成:胎盘提取物的制备方法,包括:用提取溶剂匀浆胎盘的步骤; 过滤均质材料以除去残留物的步骤; 向滤液中加水并将混合物分离成下层和上清液的步骤; 从下层挥发有机溶剂的步骤; 向剩余溶液中加入醇溶液的步骤; 加入碱溶液,然后在水浴中加热的步骤; 用酸溶液调节pH的步骤; 加入乙醚,混合和分离混合物层的步骤; 以及收集和纯化醚层的步骤。 胎盘提取物含有nandrolone,睾酮,雌二醇和雌酮。 用于预防或治疗贫血的药物组合物含有胎盘提取物作为活性成分。