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    • 44. 发明公开
    • Aqueous nanoemulsion composition containing mastic gum
    • 含有主胶的水性纳米组合物
    • KR20120018609A
    • 2012-03-05
    • KR20100081556
    • 2010-08-23
    • MNC WATERYU HYO GYOUNG
    • JI HONG GEUNYU HYO GYOUNGHYUN IN SUK
    • A61K47/30A61K9/10A61K47/36A61K47/44
    • A61K8/97A61K8/345A61K8/8152A61K8/922A61K2800/40A61Q19/00B82Y5/00
    • PURPOSE: An aqueous nanoemulsion composition containing mastic gum is provided to ensure bioavailability and for excellent storage and pH stability. CONSTITUTION: An aqueous nanoemulsion composition containing mastic gum contains 5-60 wt% of mastic gum, 5-50 wt% of oil, 3-30 wt% of polyglycerin fatty acid ester as an emulsifier, 0.1-15 wt% of sugar fatty acid ester, 1-40 wt% of propylene glycol, and water for the remaining amount. The mastic gum is obtained from Pistacia lentiscus. The viscosity of the composition is 1-100 Cp. The oil includes olive oil, sunflower seed oil, MCT(medium chain triglyceride), jojoba oil, or macadamia oil. The polyglycerin fatty acid ester includes polyglycerin stearic acid, polyglycerin myristic acid, polyglycerin oleic acid, or polyglycerin lauric acid.
    • 目的:提供含有乳香胶的含水纳米乳液组合物,以确保生物利用度和优异的储存和pH稳定性。 构成:含有乳香胶的含水纳米乳液组合物含有5-60重量%的乳香胶,5-50重量%的油,3-30重量%的作为乳化剂的聚甘油脂肪酸酯,0.1-15重量%的糖脂肪酸 酯,1-40重量%的丙二醇和剩余量的水。 乳香胶是从小松子获得的。 组合物的粘度为1-100cp。 油包括橄榄油,向日葵籽油,MCT(中链甘油三酯),霍霍巴油或澳洲坚果油。 聚甘油脂肪酸酯包括聚甘油硬脂酸,聚甘油肉豆蔻酸,聚甘油油酸或聚甘油月桂酸。
    • 47. 发明公开
    • 어류 정액 또는 알로부터 분리된 DNA 중합체 단편복합체 및 그의 제조방법
    • 从鱼类分离的多核苷酸片段复合物及其分离方法
    • KR1020090079413A
    • 2009-07-22
    • KR1020080005352
    • 2008-01-17
    • 정래준
    • 정래준
    • C12N15/12C12N15/10
    • C07K14/461A61K2800/40C12N15/10
    • A method for manufacturing DNA polynucleotide which is isolated from semen or egg of fishes is provided to have DNA polynucleotide fragment with high yield by performing enzyme lysis process. A method for manufacturing a DNA polynucleotide fragment which is isolated from semen or egg of fishes comprises thawing process of the semen or egg, enzyme lysis process, sterilization process, molecular weight reduction process, precipitation process and dry-granulation process. The enzyme lysis process is performed at pH 7.0-7.4 and 43-47°C. The sterilization process is performed at 100-109°C for 10 to 30 minutes using weak acid. The molecular weight reduction process is performed at pH 4.0-4.4 and 68-72°C. The DNA polynucleotide fragment has molecular formula, C9.83H12.33N3.72O6.01PNa and 50-1500 kDa of molecular weight. The DNA fragment is hardly soluble in water and alkali, soluble in alcohol in alcohol and is insoluble in ether and acetone.
    • 通过进行酶裂解处理,提供从鱼类的精液或卵分离的DNA多核苷酸的制造方法,以具有高产率的DNA多核苷酸片段。 从鱼类精液或卵中分离出的DNA多核苷酸片段的制造方法,包括精液或卵的解冻过程,酶裂解过程,杀菌工艺,分子量降低过程,沉淀法和干法造粒法。 酶裂解过程在pH 7.0-7.4和43-47℃下进行。 使用弱酸在100-109℃进行灭菌10〜30分钟。 分子量降低过程在pH 4.0-4.4和68-72℃下进行。 DNA多核苷酸片段具有分子式C9.83H12.33N3.72O6.01PNa和50-1500kDa的分子量。 DNA片段几乎不溶于水和碱,溶于乙醇中,不溶于乙醚和丙酮。