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    • 44. 发明公开
    • 베타-아밀로이드에 의한 신경독성 경감용 조성물
    • 用于抑制由β-淀粉样蛋白诱导的神经毒性的组合物,以及使用其抑制神经毒性的方法
    • KR1020040099601A
    • 2004-12-02
    • KR1020030031633
    • 2003-05-19
    • 주식회사 보타메디
    • 신현철황혜정이봉호최병욱이상한김환묵김형진
    • A61K36/03A61P25/28A61P3/10
    • A61K36/03A61K38/168A61K2236/33A61K2236/51Y10S514/886
    • PURPOSE: Provided are a composition for inhibiting neurotoxicity induced by beta-amyloid peptide, and a method for inhibiting neurotoxicity by using the same. The composition contains the extract of seaweeds as an active ingredient and thus is used for the treatment of amyloid diseases, such as alzheimer's disease, chronic inflammation, multiple myeloma, type ii diabetes, Creutzfeldt-jakob. CONSTITUTION: The composition for inhibiting neurotoxicity induced by beta-amyloid peptide is characterized by containing, as an active ingredient, the extract of seaweeds selected from the group consisting of Ecklonia cava, Ishige sinicola, Hizikia fusiformis, and Sargassum fulvellum, in the amount of 3-25μg/ml. The extract is obtained by extracting seaweed in the solvent selected from the group consisting of methanol, ethanol, ethylacetate, acetonitrile, acetone, water and their mixture at 5-120 deg.C for 0.5 to 24 hours, ad distilling the extract under reduced pressure.
    • 目的:提供一种用于抑制由β-淀粉样蛋白肽诱导的神经毒性的组合物,以及通过使用该组合物来抑制神经毒性的方法。 该组合物含有海藻提取物作为活性成分,因此用于治疗淀粉样疾病,例如阿尔茨海默氏病,慢性炎症,多发性骨髓瘤,II型糖尿病,Creutzfeldt-jakob。 构成:用于抑制由β-淀粉样蛋白肽诱导的神经毒性的组合物的特征在于,含有选自Ecklonia cava,Ishige sinicola,Hizikia fusiformis和Sargassum fulvellum的海藻提取物作为活性成分,其量为 3-25μg/ ml的。 通过在5-120℃下从选自甲醇,乙醇,乙酸乙酯,乙腈,丙酮,水及其混合物的溶剂中提取海藻0.5至24小时,提取海藻提取物,在减压下蒸馏提取物 。
    • 45. 发明公开
    • 성기능 개선 조성물
    • 组合物改善性功能障碍
    • KR1020040048166A
    • 2004-06-07
    • KR1020020075948
    • 2002-12-02
    • 주식회사 에스비엠주식회사 보타메디
    • 이행우신현철윤희성배종현이창환
    • A61K36/02A61P15/00
    • PURPOSE: A composition to improve sexual dysfunction containing a seaweed extract of Ecklonia cava, Hizikia fusiforme, Sargassum fulvellum and Sargassum fulvellum as a main component, together with an extract of red ginseng, grapes and Zizyphi Fructus is provided. It causes firmer longer lasting erections with increased sensation and more powerful ejaculations when taken to a patient having erectile dysfunction. CONSTITUTION: The composition to improve sexual dysfunction contains 0.1 to 50% by weight of a seaweed extract, 1 to 50% by weight of grape juice, 1 to 50% by weight of a red ginseng extract and 1 to 50% by weight of a Zizyphi Fructus extract on the basis of solids. The seaweed extract contains more than 0.05% by weight of fucosterol and more than 10% by weight of a phloroglucinol-based compound. The seaweed is selected from brown algae, Sargassum fulvellum, green laver, Ecklonia cava, Hizikia fusiforme, kelp, Rhei Rhizoma, laver, Gracilaria verrucosa or the like.
    • 目的:提供含有Ecklonia cava海草提取物,Hizikia fusiforme,Sargassum fulvellum和Sargassum fulvellum作为主要成分的性功能障碍的组合物,以及红参,葡萄和Zizyphi Fructus的提取物。 当引起勃起功能障碍的患者时,它会引起更强烈的持续勃起,增加感觉和更强大的射精。 构成:改善性功能障碍的组合物含有0.1〜50重量%的海藻提取物,1〜50重量%的葡萄汁,1〜50重量%的红参提取物和1〜50重量%的 Zizyphi Fructus提取物在固体的基础上。 海藻提取物含有超过0.05重量%的岩藻甾醇和超过10重量%的间苯三酚类化合物。 海草选自棕藻,马鞭草,绿紫菜,Ecklonia cava,Hizikia fusiforme,海带,Rhei Rhizoma,紫菜,Gracilaria verrucosa等。