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    • 31. 发明公开
    • 암 진단용 바이오마커 및 이를 이용한 암세포 분리 방법
    • 用于诊断癌症的生物标记物和使用其分离癌细胞的方法
    • KR1020130081952A
    • 2013-07-18
    • KR1020120003081
    • 2012-01-10
    • 삼성전자주식회사아주대학교산학협력단
    • 김연정김유선이정건백상현오진미정효영
    • G01N33/574C12N5/095
    • C07K14/705C12Q1/6881C12Q1/6886C12Q2600/158G01N33/57484
    • PURPOSE: A biomarker for diagnosis of cancer is provided to be able to efficiently detect and isolate the cancer stem cell or the epithelial-mesenchymal transited circulating tumor cell. CONSTITUTION: A biomarker for detecting the cancer stem cell or the epithelial-mesenchymal transited circulating tumor cell includes Caveolin-1 of which the expression relatively increases in the cancer cell compared to the normal cell. A kit for detecting the cancer stem cell or the epithelium-mesenchymal transited circulating tumor cell includes Caveolin-1 or an antibody specifically binding to its fragment, or its antigen binding fragment. A method of isolating the cancer stem cell or the epithelium-mesenchymal transited circulating tumor cell comprises a step of detecting the cancer stem cell or the epithelium-mesenchymal transited circulating tumor cell in which Caveolin-1 is expressed on the cell surface from a biological sample; and a step of isolating the detected cancer stem cell or epithelium-mesnchymal transited circulating tumor cell from the biological sample. [Reference numerals] (AA) EMT derived cancer cell; (BB) Cancer cell
    • 目的:提供诊断癌症的生物标志物,以便能够有效地检测和分离癌症干细胞或上皮 - 间质转运的循环肿瘤细胞。 构成:用于检测癌症干细胞或上皮 - 间质转运循环肿瘤细胞的生物标志物包括与正常细胞相比,癌细胞中表达相对增加的窖蛋白-1。 用于检测癌症干细胞或上皮 - 间质转运循环肿瘤细胞的试剂盒包括窖蛋白-1或与其片段特异性结合的抗体或其抗原结合片段。 分离癌症干细胞或上皮 - 间质转运循环肿瘤细胞的方法包括检测癌细胞或上皮 - 间质转运循环肿瘤细胞的步骤,其中窖蛋白-1在细胞表面上从生物样品中表达 ; 以及从生物样品中分离检测到的癌干细胞或上皮 - 细胞间充质循环肿瘤细胞的步骤。 (AA)EMT衍生的癌细胞; (BB)癌细胞
    • 37. 发明公开
    • 표적 물질 검출 및 분리 장치, 및 이를 이용한 표적 물질 검출 및 분리 방법
    • 用于检测和分离目标生物分子的装置和使用该目标的生物分子检测和分离目标生物分子的方法
    • KR1020130060009A
    • 2013-06-07
    • KR1020110126281
    • 2011-11-29
    • 삼성전자주식회사서강대학교산학협력단
    • 이헌주이정건최정우김연정박종면송미정오진미
    • G01N33/53G01N33/68G01N33/52C12Q1/68
    • G01N33/54306G01N33/54366G01N33/5302
    • PURPOSE: An apparatus for detecting and isolating a target material, and a method for detecting and isolating the target material using the same are provided to efficiently detect and isolate a small amount of the target material in a sample. CONSTITUTION: An apparatus for detecting and isolating a target material comprises a target material binding part(100), a signal generation part(200), a first separation part(300), and a second separation part(400). The target material binding part specifically binds with a target material. The signal generator is connected to the target material binding part and generates a detectable signal. The first separation part is connected to the signal generation part. The second separation part is fixed at a solid support(500) and specifically binds to the first separation part. The first and second separation parts have a cleavage site when binding each other.
    • 目的:提供一种用于检测和分离目标材料的装置,以及用于检测和分离目标材料的方法,以有效地检测和分离样品中少量的目标材料。 构成:用于检测和分离目标材料的装置包括目标材料结合部分(100),信号产生部分(200),第一分离部分(300)和第二分离部分(400)。 目标材料结合部分与目标材料特异性结合。 信号发生器连接到目标材料结合部分并产生可检测的信号。 第一分离部分连接到信号产生部分。 第二分离部分固定在固体支持物(500)上并且特异性地结合到第一分离部分。 当彼此结合时,第一和第二分离部分具有切割位点。
    • 38. 发明公开
    • 키패드 어셈블리
    • 键盘装配
    • KR1020080023871A
    • 2008-03-17
    • KR1020060087972
    • 2006-09-12
    • 삼성전자주식회사
    • 조영완김영석김연정
    • H01H13/715H01H13/70H01H13/704
    • A keypad assembly is provided to prevent deterioration of data input sensitivity by forming a mechanical metal dome and a touch pad on a single substrate, thereby realizing a high quality terminal. A keypad assembly(10) includes a top film(12), a bottom film(14), a touch pad input circuit, a top dome electrode(122), a metal dome(15), a bottom dome electrode(142), a metal dome key input circuit, at least one switching device, and a control unit. The top film has a plurality of top electrodes(121) at regular intervals. The bottom film is stacked at a predetermined interval with the top film and has bottom electrodes(141) corresponding to the top electrodes. The touch pad input circuit is electrically connected to the top and bottom electrodes. The top dome electrode is formed inside the top film. The metal dome is electrically connected to the top dome electrode. The bottom dome electrode is formed inside the bottom film to be in contact with the metal dome by pressing the metal dome. The metal dome key input circuit is electrically connected to the top and bottom electrodes. The one switching device is installed inside the top or bottom electrode to switch to the touch pad input circuit or the metal dome key input circuit. The control unit controls the switching device according to user's mode conversion input.
    • 通过在单个基板上形成机械金属圆顶和触摸板来提供键盘组件以防止数据输入灵敏度的恶化,从而实现高质量的端子。 键盘组件(10)包括顶部薄膜(12),底部薄膜(14),触摸板输入电路,顶部圆顶电极(122),金属圆顶(15),底部圆顶电极(142) 金属圆顶键输入电路,至少一个开关装置和控制单元。 顶部膜以规则的间隔具有多个顶部电极(121)。 底部膜与顶部膜以预定的间隔堆叠,并且具有对应于顶部电极的底部电极(141)。 触摸板输入电路电连接到顶部和底部电极。 顶顶电极形成在顶膜内。 金属圆顶电连接到顶部圆顶电极。 底部圆顶电极形成在底部薄膜的内部,以通过按压金属圆顶与金属圆顶接触。 金属圆顶键输入电路电连接到顶电极和底电极。 一个开关装置安装在顶部或底部电极内部,以切换到触摸板输入电路或金属圆顶键输入电路。 控制单元根据用户的模式转换输入控制切换装置。