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11. 发明公开

KR1020140013161A 유전자 발현 조절 장치 有权
标题翻译：氢磁反应基因调控因子及其应用方法
公开(公告)号：KR1020140013161A
公开(公告)日：2014-02-05
申请号：KR1020120078812
申请日：2012-07-19
申请人： 강릉원주대학교산학협력단 , 김연숙 , 이윤우 , 주식회사 진바이오시스 , 이정근 , 이홍근 , 이대성 , 이대관
发明人： 이석근 , 김연숙 , 이윤우 , 이정근 , 이홍근 , 이대성 , 이대관
IPC分类号： C12Q1/68 , G01N27/72 , G01N27/30
CPC分类号： C12N15/63 , G01N27/30 , G01N27/72
摘要： A hydrogen magnetic reaction gene regulator of the present invention comprises: an even number of electromagnets arranged at equidistant intervals on a virtual circle so as to form magnetic fields capable of simulating a DNA double helix structure; and an electromagnet driving unit for sequentially driving a pair of facing electromagnets among the electromagnets according to a base sequence of a sense strand or anti-sense strand in a base pair of a target DNA double helix, using a polarity of forming polar magnetic fields or semi-polar magnetic fields corresponding to the base pair of the target DNA double helix. Therefore, the hydrogen magnetic reaction gene regulator of the present invention can form polar magnetic fields or semi-polar magnetic fields capable of activating or inactivating genes.
摘要翻译：本发明的氢磁反应基因调节剂包括：在虚拟圆上以等间距排列的偶数个电磁体，以形成能够模拟DNA双螺旋结构的磁场; 以及电磁驱动单元，其使用形成极性磁场的极性，根据目标DNA双螺旋的碱基对中的有义链或反义链的碱基序列依次驱动电磁体中的一对面向电磁体，或对应于目标DNA双螺旋的碱基对的半极性磁场。因此，本发明的氢磁反应基因调节剂可以形成能够激活或失活基因的极性磁场或半极性磁场。

12. 发明公开

KR1020120099553A 생체 적합 온도 내에서 큐리 온도를 가지는 자성 나노입자 및 그 제조 방법 有权
标题翻译：在生物降解温度下具有CURIE温度的纳米颗粒及其制备方法
公开(公告)号：KR1020120099553A
公开(公告)日：2012-09-11
申请号：KR1020110009824
申请日：2011-01-31
申请人： 고려대학교 산학협력단
发明人： 김영근 , 우준화 , 민지현 , 이지성 , 정재호
IPC分类号： A61K9/16 , A61K47/48 , A61K47/02 , A61K49/08
CPC分类号： G01N27/72 , A61K49/1827 , A61K49/1851 , A61K49/1866 , A61K49/1875 , C01G45/12 , C01P2002/72 , C01P2002/85 , C01P2004/04 , C01P2004/62 , C01P2004/64 , C01P2006/42 , G01N33/587 , A61K9/16 , A61K47/02 , A61K47/50 , A61K49/08
摘要： PURPOSE: A magnetic nano-particle and a manufacturing method thereof having curie temperature within biocompatible temperature is provided to minimize side effects due to ferromagnetic characteristics and to be used for effective scanning and separation of biologics. CONSTITUTION: A magnetic nano-particle(10) having curie temperature within a temperature range of -80-41deg. Celsius comprises rare earth metal, divalent metal, and transition metal oxide The rare earth metal is lanthanum series metals. The divalent metal is alkaline earth metal or lead (Pb). The transition metal oxide is manganese oxide. The magnetic nano-particle comprises 0.5-1 molar fraction of the rare earth metal and 0.01-0.5 molar fraction of the divalent metal based on 1 molar fraction of the transition metal. A manufacturing method of the magnetic nano-particle comprises the following steps: forming the magnetic nano-particle by reducing a rare earth metal precursor, transition metal oxide precursor and the divalent metal precursor; and heat-treating the magnetic nano-particle.
摘要翻译：目的：提供一种具有居里温度在生物相容温度内的磁性纳米颗粒及其制造方法，以使由于铁磁特性引起的副作用最小化，并用于生物制剂的有效扫描和分离。构成：具有居里温度在-80-41℃范围内的磁性纳米颗粒（10）。摄氏度包括稀土金属，二价金属和过渡金属氧化物稀土金属是镧系金属。二价金属是碱土金属或铅（Pb）。过渡金属氧化物是氧化锰。基于1摩尔分数的过渡金属，磁性纳米颗粒包含0.5-1摩尔分数的稀土金属和0.01-0.5摩尔分数的二价金属。磁性纳米颗粒的制造方法包括以下步骤：通过还原稀土金属前体，过渡金属氧化物前体和二价金属前体形成磁性纳米颗粒; 并对磁性纳米颗粒进行热处理。

13. 发明公开

KR1020110089643A 나노 자성 입자 및 그를 이용한 급성 심근 경색증을 진단하는 방법 无效
标题翻译：纳米磁性颗粒和使用其的诊断急性心肌梗塞的方法
公开(公告)号：KR1020110089643A
公开(公告)日：2011-08-09
申请号：KR1020100009136
申请日：2010-02-01
申请人： 엘지이노텍 주식회사
发明人： 김영민
IPC分类号： B82B1/00 , A61B5/0205 , G01N27/72 , G01N33/50
CPC分类号： G01N33/54326 , A61B5/0205 , B82Y99/00 , G01N27/72 , G01N33/346 , G01N2800/32
摘要： PURPOSE: Magnetic nanoparticles and a method for diagnosing acute myocardiac infraction using the same are provided to combine antigen in blood with the myocardium indicator of the magnetic nanoparticles and measure the magnetic intensity of the magnetic nanoparticles. CONSTITUTION: Magnetic nanoparticles include superparamagnetic nanoparticle(110), a polymer film(120), and a myocardium indicator(130). The polymer film is coated on the outer circumference of the nanoparticle. The myocardium indicator is conjugated with the polymer film. The myocardium indicator is one of myoglobin, ck-mb, and cardiac troponin complex. The polymer film is formed based on hydrophilic polymeric materials. A method for diagnosing the acute myocardiac infraction includes the following: The magnetic nanoparticles are prepared. Blood is injected into the magnetic nanoparticles. The antigen in the blood is reacted with the myocardium indicator of the magnetic nanoparticles. Reacted magnetic nanoparticles are extracted. Magnetic field is applied to the extracted nanoparticles. The magnetic intensity of the magnetic nanoparticles is detected. Based on the detected magnetic intensity, the acute myocardiac infraction is diagnosed.
摘要翻译：目的：提供磁性纳米粒子和使用该方法诊断急性心肌梗死的方法，将血液中的抗原与磁性纳米颗粒的心肌指示剂结合，并测量磁性纳米粒子的磁强度。构成：磁性纳米颗粒包括超顺磁性纳米颗粒（110），聚合物膜（120）和心肌指示物（130）。聚合物膜涂覆在纳米颗粒的外圆周上。心肌指示剂与聚合物膜共轭。心肌指标是肌红蛋白，ck-mb和心肌肌钙蛋白复合物之一。聚合物膜基于亲水性聚合物材料形成。用于诊断急性心肌梗死的方法包括：制备磁性纳米粒子。将血液注入磁性纳米粒子。血液中的抗原与磁性纳米颗粒的心肌指示剂反应。提取反应的磁性纳米粒子。对提取的纳米粒子施加磁场。检测磁性纳米颗粒的磁强度。根据检测到的磁场强度，诊断急性心肌梗死。

14. 发明公开

KR1020100115497A 미세 금속 검출장치 有权
标题翻译：用于检测精细金属的装置
公开(公告)号：KR1020100115497A
公开(公告)日：2010-10-28
申请号：KR1020090034102
申请日：2009-04-20
申请人： 송규홍 , 박정화
发明人： 송규홍 , 박정화
IPC分类号： G01R33/24 , G01R29/08 , G01R23/02
CPC分类号： G01N23/18 , G01N27/72 , G01N33/20 , G01R33/02
摘要： PURPOSE: A minute metal detection device is provided to accurately detect a metallic nanoparticle included in a target object by detecting a frequency change by comparing a frequency, which is varied by the magnetic field interference of the metallic nanoparticle, with a reference frequency. CONSTITUTION: A conveyor transfers a target object which includes a metal to be detected in a one direction. A detection part(200) is installed to be separated from the conveyor. A controller(300) determines whether the target object includes a metallic nanoparticle in the object based on the change of a resonant frequency. The controller comprises a V-F oscillator(310) forming an oscillation frequency through power supplied from the outside. The controller comprises an amplifier(340), which outputs an electric potential value which is outputted through comparing part(330), and an output part(350).
摘要翻译：目的：提供微小的金属检测装置，通过将由金属纳米颗粒的磁场干涉变化的频率与参考频率进行比较，通过检测频率变化来精确地检测包括在目标对象中的金属纳米颗粒。构成：输送机在一个方向上传送包括要检测的金属的目标物体。检测部（200）安装成与输送机分离。控制器（300）基于谐振频率的变化来确定目标对象是否包括物体中的金属纳米颗粒。控制器包括通过从外部供应的电力形成振荡频率的V-F振荡器（310）。控制器包括输出通过比较部分（330）输出的电位值的放大器（340）和输出部分（350）。

15. 发明公开

KR1020040055383A 자화 페어 감지 센서 및 이를 이용한 센싱 셀 어레이 无效
标题翻译：使用相同的磁化对感测传感器和感应细胞阵列
公开(公告)号：KR1020040055383A
公开(公告)日：2004-06-26
申请号：KR1020020082035
申请日：2002-12-21
申请人： 에스케이하이닉스 주식회사
发明人： 강희복 , 정동윤 , 임재형 , 박영진 , 이계남
IPC分类号： G11C11/15
CPC分类号： G01N27/72 , G01N33/49 , H01L43/08
摘要： PURPOSE: A magnetization pair sensing sensor and a sensing cell array using the same are provided to separate components of a peripheral material into electrical components and thus to analyze a value of a magnetic flux density according to the same quantitatively. CONSTITUTION: A MTJ(Magnetic Tunneling Junction) device(21) is formed with a free magnetic layer(18), a tunnel junction layer(19) and a fixed magnetic layer(20). A switching device is formed on a bottom of the fixed magnetic layer of the MTJ device, and outputs a current sensed in the MTJ cell to a sense bit line. And a sense word line is formed on an upper part of the free magnetic layer, and applies different bias voltages to the MTJ device. When a magnetic flux line of the fixed magnetic layer is transferred to the free magnetic layer, it has different magnetic flux density according to the peripheral material, and thus the current being output through the switching device has different values.
摘要翻译：目的：提供磁化对检测传感器和使用其的感测单元阵列以将外围材料的组件分离成电气部件，并因此根据定量分析磁通密度的值。构成：MTJ（磁隧道结）装置（21）形成有自由磁性层（18），隧道结层（19）和固定磁性层（20）。开关装置形成在MTJ装置的固定磁性层的底部，并将在MTJ单元中感测的电流输出到感测位线。并且在自由磁性层的上部形成感测字线，并向MTJ器件施加不同的偏置电压。当固定磁性层的磁通线被转移到自由磁性层时，根据外围材料具有不同的磁通密度，因此通过开关装置输出的电流具有不同的值。

16. 发明授权

KR100405074B1 중합체조성물또는예비중합체조성물의양을측정하는방법 失效
公开(公告)号：KR100405074B1
公开(公告)日：2004-03-24
申请号：KR1019980707027
申请日：1996-07-24
申请人： 쓰리엠 컴퍼니
发明人： 요크기티스엘라인엠. , 체임버레인크레이그에스.
IPC分类号： G01N27/00 , G01N33/00
CPC分类号： G01N27/72 , G01N33/442 , Y10T436/13
摘要： A method for measuring the quantity of a polymeric or pre-polymeric composition within a given volume that includes combining the polymeric or pre-polymeric composition with a plurality of microparticles having a non-ferromagnetic or non-ferrimagnetic core provided with a coating that is ferromagnetic, ferrimagnetic, or conductive, to form an admixture in which the microparticles are substantially uniformly dispersed throughout the composition. The microparticles have a detectable electromagnetic characteristic which correlates with the amount of the composition within a given volume. The electromagnetic characteristic of the microparticles is then measured to determine the quantity of the composition within a given volume.
摘要翻译：用于测量给定体积内的聚合物或预聚合物组合物的量的方法，包括将聚合物或预聚合物组合物与具有非铁磁性或非亚铁磁性核的多个微粒组合，所述微粒具有铁磁涂层，亚铁磁性或导电性，以形成其中微粒基本均匀分散在整个组合物中的混合物。微粒具有可检测的电磁特性，其与给定体积内的组合物量相关。然后测量微粒的电磁特性以确定给定体积内组合物的量。

17. 发明授权

KR100327075B1 가공에대한공작물의적합성을측정하는방법및장치 失效
标题翻译：用于确定加工工件可靠性的方法和装置
公开(公告)号：KR100327075B1
公开(公告)日：2002-09-27
申请号：KR1019970706026
申请日：1996-02-22
申请人： 더 글리슨 웍스
发明人： 스즈크체판스키토마스엘.
IPC分类号： G01N27/72
CPC分类号： G01N27/72 , Y10T409/100159 , Y10T409/30112
摘要： 내용없음

18. 发明授权

KR1019900002496B1 강자성체의 마모탐지기 및 탐지방법 失效
标题翻译：铁磁体磨损检测器及检测方法
公开(公告)号：KR1019900002496B1
公开(公告)日：1990-04-16
申请号：KR1019860008512
申请日：1986-10-10
申请人： 아토믹에너지오브카나다리밋티드
发明人： 키스더블유.쳄버스
IPC分类号： G01F1/56 , G01N15/06
CPC分类号： G01N27/72 , G01N15/0656 , G01N33/2858
摘要： The detector (14) includes a sensing coil (18) arranged to form the inductance coil of a radio frequency oscillator (20) arranged to produce an electrical signal at a base frequency, a magnetic trap producing a magnetic field, and a support for supporting the sensing coil and the magnetic trap in juxtaposition to another. When the coil is disposed within or in proximity of the fluid stream and electrically connnected to the oscilator, energization of the magnetic trap causes ferromagnetic particulate material proximate the coil to be attracted toward the coil resulting in a deviation of the frequency of the signal from the base frequency proportional to the concentration of ferromagnetic particulate material in the fluid stream.
摘要翻译：检测器（14）包括检测线圈（18），该感测线圈（18）被布置成形成射频振荡器（20）的电感线圈，该射频振荡器被布置成产生基频的电信号，产生磁场的磁捕获器和支撑感测线圈和磁捕获器并置到另一个。当线圈设置在流体流中或与流体流接触并且与电子连接到振荡器之间时，磁捕获器的通电将导致线圈附近的铁磁颗粒材料被吸引到线圈，从而导致信号频率偏离基频与流体流中铁磁颗粒物质的浓度成正比。

19. 发明公开

KR20180054716A 리튬을 함유하는 이온-교환된 화학적으로 강화된 유리의 특성화 방법 审中-公开
公开(公告)号：KR20180054716A
公开(公告)日：2018-05-24
申请号：KR20187010574
申请日：2016-09-16
申请人： CORNING INC
发明人： ROUSSEV ROSTISLAV VATCHEV , SCHNEIDER VITOR MARINO , ANDREWS RYAN CLAUDE
IPC分类号： G01N27/72 , C03C21/00 , G01N27/60 , G01N33/38
CPC分类号： G01N27/60 , C03C21/002 , G01N27/72 , G01N33/386
摘要： 리튬을함유하는이온-교환된화학적으로강화된유리를특성화하는방법이개시된다. 상기방법은칼륨-함유염(salt), 특히칼륨및 나트륨모두를갖는염에서생성된표면응력스파이크를갖는화학적으로강화된 Li-함유유리에서의응력프로파일의품질제어를수행할수 있게한다. 상기방법은, 표면압축및 스파이크깊이의측정, 및스파이크하단에서의압축및 전체중심장력뿐만아니라중심장력에대한기여도의측정, 및응력프로파일의깊은영역과스파이크가교차하는무릎에서의응력의계산을허용한다. 상기측정들은스파이크이외의상기기판내부의대부분에서거의-포물선형상인상업적으로중요한프로파일에대한측정이다.

20. 发明公开

KR1020170076778A 전단 가공 후의 무방향성 전자 강판의 철손 예측 방법 审中-实审
标题翻译：预测剪切后无取向电工钢板铁损的方法
公开(公告)号：KR1020170076778A
公开(公告)日：2017-07-04
申请号：KR1020177014879
申请日：2015-11-02
申请人： 제이에프이 스틸 가부시키가이샤
发明人： 오무라다케시 , 자이젠요시아키 , 센다구니히로
IPC分类号： G01R33/12
CPC分类号： G01N27/72 , G01R33/12 , H01F1/16
摘要： 무방향성전자강판을어느폭으로전단가공한, 전단가공후의무방향성전자강판의철손을예측하는데있어서, 전단가공후의무방향성전자강판의철손 Wt(B) 을, 전단가공에의해가공변형이도입된가공비영향부의철손 Wn(B) 과, 가공변형이도입되어있지않은가공영향부의철손 Wi(B) 를사용하여, 소정의관계식에의해계산한다.
摘要翻译：根据无方向性电磁钢板预测剪切取向占空比电磁钢板，其中所述宽度，所述磁芯损耗重量（B）剪切取向占空比电磁钢板之后，处理应变由剪切引入后的剪切处理时，铁损使用铁损Wn的（B）的处理成本影响区，以及不被引入加工应变效果处理铁损无线（B）部分是通过预定等式进行计算。

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