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    • 15. 发明公开
    • 허수테논을 포함하는 간암 억제용 조성물
    • 用于抑制含有HIRSUTENON的肝癌组合物
    • KR1020050025761A
    • 2005-03-14
    • KR1020030062592
    • 2003-09-08
    • 이형주서영준이기원이민원
    • 이형주이기원이상준이민원서영준
    • A61K31/12
    • A61K31/122A23L33/10A23V2002/00A23V2200/308
    • A composition for inhibiting liver cancer comprising hirsutenone is provided, which hirsutenone inhibits activity of MMP(matrix metalloproteinase) that is an enzyme relating to movement and metastasis of cancer and dissolves the outercellular matrix without side effects, so that it can inhibit progress and metastasis of liver cancer. The composition for inhibiting liver cancer comprises hirsutenone represented by formula (1) as an effective component and pharmaceutically acceptable carriers, wherein the hirsutenone is prepared by extracting Aluns hirsuta (Spach) Rupr. or its dried product with solvent such as acetone or by chemical synthesis. The health improving food having inhibitory effects on progress and metastasis of liver cancer comprises hirsutenone.
    • 本发明提供一种含有高分子亚麻酸的肝癌抑制组合物,其中多环酮抑制与癌移动和转移有关的酶(MMP)(基质金属蛋白酶)的活性,可溶解外部细胞基质而无副作用,从而抑制肝细胞的进展和转移 肝癌。 用于抑制肝癌的组合物包括作为有效成分的式(1)表示的高新棉素和药学上可接受的载体,其中通过提取Aluns hirsuta(Spach)Rupr制备高分子酮。 或其干燥产物与溶剂如丙酮或通过化学合成。 具有对肝癌进展和转移的抑制作用的健康改善食物包括高新棉素。