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111. 发明公开

KR1020090011557A 미세유로형 센서 복합 구조물 有权
标题翻译：微流体传感器复合结构
公开(公告)号：KR1020090011557A
公开(公告)日：2009-02-02
申请号：KR1020070075254
申请日：2007-07-26
申请人： 주식회사 아이센스 , 나노디텍 코포레이션
发明人： 최문희 , 정승현 , 김영훈 , 박주헌 , 남학현 , 차근식
IPC分类号： G01N33/49 , G01N33/48 , G01N35/00 , G01N33/00
CPC分类号： B01L3/502707 , B01L3/5027 , B01L2200/0621 , B01L2200/143 , B01L2300/0645 , B01L2300/0681 , B01L2300/0816 , B01L2300/0867 , B01L2300/0887 , B01L2400/0406
摘要： A micro channel type sensor composite structure is provided to be simply manufactured by using universally used organic polymer, to be mass produced easily and to be used as a sensor for field measurement by using electrochemistry detection method. A micro channel type sensor composite structure contains: a lower plate(100) having a reference electrode, a working electrode and an electrode connecting part(103); two micro channels branched off from a sample introducing part(203) and a sample introducing part, connected to a detection unit exposing a reference electrode(102) and a working electrode(101); a mixing portion including an aeration section and an air outlet n the micro channels in which a substrate store is placed in order to reach so that a substrate solution dissolved by a sample solution temporally later reaches to the detection unit; and an absorbing part(209) absorbing fluid passing through the detection unit; a middle substrate(200) having an aeration section and laminated on a lower plate; and an upper plate(300) laminated in order to induce capillary phenomena in the micro channel formed in the middle substrate.
摘要翻译：提供微通道型传感器复合结构，简单地通过使用普遍使用的有机聚合物制造，可以容易地批量生产并且通过使用电化学检测方法用作用于现场测量的传感器。微通道型传感器复合结构包括：具有参考电极的下板（100），工作电极和电极连接部（103）; 从与样品引入部分（203）分离的两个微通道和与暴露参考电极（102）和工作电极（101）的检测单元连接的样品引入部分; 混合部分，其包括曝气部分和微通道之间的空气出口，其中放置基板存储器，以便使得随后由样品溶液溶解的底物溶液到达检测单元; 以及吸收通过所述检测单元的流体的吸收部（209）具有通气部分并层压在下板上的中间基板（200）; 和上板（300），以便在形成在中间基板中的微通道中引起毛细管现象。

112. 发明公开

KR1020080114110A 유기물질 측정을 위한 산화전극 및 그 제조방법 失效
标题翻译：用于测量有机材料的氧化电极
公开(公告)号：KR1020080114110A
公开(公告)日：2008-12-31
申请号：KR1020070063359
申请日：2007-06-27
申请人： 주식회사 아이센스
发明人： 강태영 , 조주영 , 황지현 , 차근식 , 남학현
IPC分类号： G01N27/30 , G01N27/26
摘要： An oxidizing electrode and a manufacturing method thereof are provided to measure the concentration of organic material reproducibly since the electrode oxidizes various organic materials effectively and induces oxygen transfer reaction stably. An oxidizing electrode for organic material measurement comprises an electrode material(101) in which metal oxide powder and conductive carbon paste are mixed and a base electrode(102) on which the electrode material is coated, an electrode body(103), and a connection wire(104) located inside the electrode body. The base electrode is connected with the connection wire so that the current generated by electrochemical reaction of the electrode material can flow to the connection wire through the base electrode.
摘要翻译：提供了一种氧化电极及其制造方法，可有效地测量有机材料的浓度，因为电极有效地氧化各种有机材料并稳定地诱导氧转移反应。用于有机材料测量的氧化电极包括其中混合有金属氧化物粉末和导电性碳糊料的电极材料（101）和其上涂覆有电极材料的基底电极（102），电极体（103）和连接电线（104）位于电极体内。基极与连接线连接，使得由电极材料的电化学反应产生的电流可通过基极流到连接线。

113. 发明授权

KR100874159B1 전기화학적 바이오센서 및 이의 측정기 有权
标题翻译： 전기화학적바이오센서및이의측정기
公开(公告)号：KR100874159B1
公开(公告)日：2008-12-15
申请号：KR1020070030346
申请日：2007-03-28
申请人： 주식회사 아이센스
发明人： 김근기 , 유재현 , 최강 , 김문환 , 남학현 , 차근식
IPC分类号： G01N33/48 , G01N27/30 , G01N27/00
CPC分类号： B01L3/545 , B01L3/5027 , B01L2300/0645 , B01L2300/0825 , B01L2300/0887 , B01L2400/0406 , G01N27/3272 , G01N35/00732 , G01N2035/00772 , G01N2035/00851
摘要： Disclosed herein are an electrochemical biosensor and a biosensor measuring device. The electrochemical biosensor includes a plurality of electrodes (104,105,107,108), capillary sample cell portions (100), reaction reagent layers, electrode connection portions (106), and a production lot information identification portion (500). The production lot information identification portion (500) is configured such that the production lot information is recorded thereon has one or more infrared absorption/reflection marks, which indicate information about differences between production lots through the printing and/or attachment of colored or colorless materials, having differences in absorbency or reflectivity of infrared rays, in conformity of a predetermined pattern or through the attachment of transparent films. The electrochemical biosensor measuring device includes a plurality of integrated photo-reflector sensing devices (702,703) that emit and receive infrared rays to identify the production lot information recorded on the production lot information identification portion of the biosensor.
摘要翻译：本文公开了电化学生物传感器和生物传感器测量装置。电化学生物传感器包括多个电极（104,105,107,108），毛细管样品池部分（100），反应试剂层，电极连接部分（106）和生产批次信息识别部分（500）。生产批次信息识别部分（500）被配置为使得生产批次信息被记录在其上具有一个或多个红外吸收/反射标记，其通过印刷和/或附着有色或无色材料来指示关于生产批次之间的差异的信息根据预定图案或通过附着透明膜而具有红外线的吸收性或反射率差异。电化学生物传感器测量装置包括发射和接收红外线以识别记录在生物传感器的生产批次信息识别部分上的生产批次信息的多个集成光反射器感测装置（702,703）。

114. 发明授权

KR100873915B1 혈액 분석 장치용 용액 용기 有权
标题翻译：用于血液化学测量的装置的溶液袋
公开(公告)号：KR100873915B1
公开(公告)日：2008-12-12
申请号：KR1020070110991
申请日：2007-11-01
申请人： 주식회사 아이센스
发明人： 하정한 , 이희준 , 강태영 , 신정원 , 남학현 , 차근식
IPC分类号： A61J1/05
CPC分类号： B01L3/505 , B01L3/567 , B01L2200/026 , B01L2200/141 , B01L2200/148 , B01L2400/065 , F16K3/24 , F16K3/246 , G01N35/1002 , Y10T436/2575
摘要： A solution container for a blood analysis equipment is provided to intercept in advance that a solution is contaminated due to external contaminants by opening the solution container when fixing a cartridge in which a solution container is housed onto a body of a blood analyzer. A solution container for a blood analysis equipment comprises a receiving part in which a solution is received, a valve body(307) which is coupled to the receiving part, and in which a penetration hole is formed in the longitudinal direction, a valve spool(309) arranged in the penetration hole of the valve body, and a solution leakage preventing part provided at the valve spool. The valve body is provided with a channel(307b) and a solution discharge pipe spaced apart from each other in a fixed distance. The solution leakage preventing part includes a first cutoff member(311a) for cutting off external leakage of a solution and a second cutoff member(311b) for cutting off or connecting the channel and the solution discharge pipe.
摘要翻译：提供一种用于血液分析设备的溶液容器，用于在将其中容纳溶液容器的药筒固定在血液分析仪的主体上时，通过打开溶液容器来预先拦截由于外部污染物而导致的溶液被污染。用于血液分析设备的溶液容器包括容纳溶液的接收部分，连接到接收部分并且在纵向上形成有穿透孔的阀体（307），阀芯（ 309），设置在阀芯的通孔内的防溶液泄漏部。阀体设置有固定距离彼此间隔开的通道（307b）和排液管。溶液泄漏防止部包括用于切断溶液的外部泄漏的第一切断部件（311a）和用于切断或连接流路的第二切断部件（311b）和排液管。

115. 发明授权

KR100762929B1 다중접속 3분할 혈당측정기 有权
标题翻译：血糖检测仪分为三个，用于多次连接
公开(公告)号：KR100762929B1
公开(公告)日：2007-10-04
申请号：KR1020050041565
申请日：2005-05-18
申请人： 주식회사 아이센스
发明人： 최강 , 김근기 , 이종수 , 남학현 , 차근식
IPC分类号： A61B5/145
摘要： 본 발명은 다중접속 3분할 혈당측정기에 관한 것으로, 혈당측정기에 커넥터가 구비되어 컴퓨터, 이동통신 단말기, PDA 등 다양한 매체에 구비되는 각 연결포트에 적용가능가능하고, 이로 인해 각 매체에 다중접속이 가능할 뿐만 아니라, 분리가능하게 결합되도록 이루어져 사용자의 필요에 따라 분리적용가능하며, 파손 및 훼손 시 특정 부분만을 교체하여 사용할 수 있을 뿐만 아니라, 다양한 목적 및 상황에 맞게 측정스트립의 교체 사용이 가능하여 사용의 편의성을 향상시킬 수 있는 다중접속 3분할 혈당측정기를 제공하기 위한 것으로, 그 기술적 구성은 전면에 측정값이나 다양한 그림정보를 표시하는 액정표시패널이 구비되고, 상기 액정표시패널의 하부 좌, 우측 적소에 전원을 인가받기 위한 전원스위치 및 기기의 조작을 위한 조작스위치가 구비되며, 하부면 중심부에 스트립 삽입구가 형성되어 측정스트립이 삽입되도록 구성되는 혈당측정기에 있어서, 하부면 좌, 우측 단부에 결합편이 각각 돌출형성되고, 하부면 중심측에 제1 연결포트가 구비되는 본체부; 상기 본체부의 하부에 분리가능하게 결합되는 제어부와 상기 제어부에 분리가능하게 결합되며, 하부면에 측정스트립이 삽입되기 위한 스트립 삽입홈이 형성되는 검사부로 구성되는 측정부; 를 포함하는 것을 특징으로 한다.
혈당측정기, 다중접속, 분할, 본체부, 측정부, 제어부, 검사부, 측정스트립

116. 发明公开

KR1020070078424A 당화단백질 검출 시스템에 적합한 시료전처리 분주 기구 有权
标题翻译：适用于糖化蛋白质电化学测定系统的样品预处理分配器
公开(公告)号：KR1020070078424A
公开(公告)日：2007-07-31
申请号：KR1020070071097
申请日：2007-07-16
申请人： 주식회사 아이센스
发明人： 남학현 , 장봉화 , 양순해 , 강보경 , 최강 , 최문희 , 이종수 , 차근식
IPC分类号： G01N33/36 , G01N33/68 , G01N33/50
摘要： A sample dispenser is provided to economically obtain an accurate result by filtering a tracer compound remaining after being bound to a glycosylated protein and then quantifying the glycosylated protein and prepare an analysis equipment without using an immuno-antibody, which is expensive and has a life-time limitation. The sample dispenser(40) comprises a capillary tube(41) for collecting sample, a sample injecting plunger(43) in which a capillary tube insertion hole(44) is formed to inject the collected sample, and a sample pre-treating container in which the sample injection plunger is mounted on one side and a sample dispensing hole(46) to dispense the sample is formed on the other side, wherein the pre-treating container contains a hemolysis preparation and a tracer compound. The dispenser further comprises a protein removing filtration layer in the sample pre-treating container.
摘要翻译：提供样品分配器以经济地获得准确的结果，通过过滤与糖基化蛋白质结合后剩余的示踪剂化合物，然后定量糖基化蛋白质并制备分析设备，而不使用昂贵的且具有寿命的免疫抗体，时间限制样品分配器（40）包括用于收集样品的毛细管（41），其中形成有毛细管插入孔（44）以注入所收集的样品的样品注射柱塞（43）和样品预处理容器在另一侧形成有一次安装样品注射柱塞并且在另一侧形成用于分配样品的样品分配孔（46），其中预处理容器含有溶血制剂和示踪剂化合物。分配器还包括样品预处理容器中的蛋白质去除过滤层。

117. 发明公开

KR1020070014292A 전기화학적 당화단백질 검출 시스템 有权
标题翻译：糖化蛋白质电化学测定系统
公开(公告)号：KR1020070014292A
公开(公告)日：2007-02-01
申请号：KR1020050068793
申请日：2005-07-28
申请人： 주식회사 아이센스
发明人： 남학현 , 장봉화 , 양순해 , 강보경 , 최강 , 최문희 , 이종수 , 차근식
IPC分类号： G01N33/36 , G01N33/68 , G01N33/50
摘要： An electrochemical determination system of glycated proteins is provided to cheaply and precisely detect the glycated proteins by simplifying the constitution and manufacturing method of a sensor, produce a large quantity of sensors without immunoglobulin, and increase storage stability of sensors during circulation. The electrochemical determination system of glycated proteins comprises: a tool for filtering a marker compounds bound to the glycated proteins and unglycated proteins from the solution wherein glycated proteins and unglycated proteins are coexisted and the marker compounds capable of selectively binding to the glycated proteins is added to the solution; and a tool for quantifying the filtered marker compounds which do not bind to the glycated proteins, wherein the amount of filtered marker compounds is determined by measuring absorbance, fluorescence, phosphorescence or chemical luminescence; and the marker compound is ferrocene derivative, anthraquinone, quinone and its derivative or organic conductive salt.
摘要翻译：提供糖化蛋白质的电化学测定系统，通过简化传感器的结构和制造方法，大量精确地检测糖化蛋白质，产生大量无免疫球蛋白的传感器，提高传感器在循环过程中的储存稳定性。糖化蛋白质的电化学测定系统包括：将糖基化蛋白质和未糖基化蛋白质共存的溶液过滤到与糖基化蛋白质结合的标记化合物和未糖基化蛋白质的工具，并且能够选择性地结合糖基化蛋白质的标记化合物被添加到解决方案; 以及用于量化不结合糖化蛋白质的过滤标记化合物的工具，其中通过测量吸光度，荧光，磷光或化学发光来测定过滤的标记化合物的量; 标记化合物是二茂铁衍生物，蒽醌，醌及其衍生物或有机导电盐。

118. 发明公开

KR1020040105429A 전기화학적 바이오센서 有权
标题翻译：电化学生物传感器，显着降低生物传感器条中HEMATOCRIT的检测错误
公开(公告)号：KR1020040105429A
公开(公告)日：2004-12-16
申请号：KR1020030036804
申请日：2003-06-09
申请人： 주식회사 아이센스
发明人： 최강 , 유재현 , 김문환 , 김주용 , 엄정희 , 남학현 , 차근식
IPC分类号： C12Q1/25
CPC分类号： C12Q1/004 , C12Q1/001
摘要： PURPOSE: An electrochemical biosensor is provided, which significantly reduces detection error by the matocrit in a biosensor strip, and rapidly detects a target material with a small amount of the sample. CONSTITUTION: A sensitive film composition comprises an enzyme, an electron transfer medium, a water-soluble polymer, fatty acid and quaternary ammonium salt. The electrochemical biosensor comprises a lower substrate(400) containing an operation electrode(104) and a supplementary electrode(105) which are coated with the sensitive film composition; a middle substrate(200) containing a sample introducing pathway portion(101) and a ventilation portion(102) which are crossed together, and a sample introducing portion(100) having an extra space portion(103) at a position where the sample introducing pathway portion(101) and the ventilation portion(102) are contacted; and an upper substrate(300) for preventing exposure of the sample introducing portion(100).
摘要翻译：目的：提供一种电化学生物传感器，可以显着降低生物传感器条中的细菌的检测误差，并用少量样品快速检测目标物质。构成：敏感膜组合物包含酶，电子转移介质，水溶性聚合物，脂肪酸和季铵盐。所述电化学生物传感器包括含有涂有所述敏感膜组合物的操作电极（104）和辅助电极（105）的下基板（400）包含交叉在一起的样品引入通路部分（101）和通气部分（102）的中间基板（200）和在样品引入位置处具有额外空间部分（103）的样品引入部分（100）通路部分（101）和通风部分（102）接触; 以及用于防止样品引入部分（100）暴露的上基板（300）。

119. 发明公开

KR1020040096039A 양방향 혈당측정기 有权
标题翻译：双向血糖测试仪，具有下部测量条带插入到主体底部的插入口
公开(公告)号：KR1020040096039A
公开(公告)日：2004-11-16
申请号：KR1020030028840
申请日：2003-05-07
申请人： 주식회사 아이센스
发明人： 김문환 , 김근기 , 최강 , 남학현 , 차근식
IPC分类号： A61B5/145
CPC分类号： A61B5/1486 , A61B5/14532 , A61B5/150022 , A61B5/150358 , A61B5/157 , A61B2562/0295 , G01N33/48785 , Y10T436/14 , Y10T436/142222 , Y10T436/143333 , Y10T436/144444
摘要： PURPOSE: A bi-directional blood glucose test meter is provided to achieve improved user convenience by permitting measurement strips to be selectively coupled to both top and bottom of the main body of the test meter. CONSTITUTION: A bi-directional blood glucose test meter(1) comprises a main body(3) having a front surface on which a liquid crystal display panel(7) for displaying a wide variety of numerical or graphical representations is mounted; an upper measurement strip(5a) inserted into the insertion port of the top of the main body in such a manner that the upper measurement strip contacts the blood in a blood collecting portion; and a lower measurement strip(5b) inserted into the insertion port of the bottom of the main body.
摘要翻译：目的：提供双向血糖测试仪，通过允许测量条选择性地耦合到测试仪的主体的顶部和底部来实现改善的用户便利性。构成：双向血糖检测仪（1）包括具有前表面的主体（3），安装有用于显示各种数字或图形表示的液晶显示面板（7）; 上测量条（5a）以上测量条接触血液收集部分中的血液的方式插入到主体的顶部的插入口中; 以及插入主体底部的插入口中的下测量条（5b）。

120. 发明授权

KR100455907B1 대면형 다공성 전극을 이용한 비분리형 효소-면역센서 失效
标题翻译： 대면형다공성전극을이용한비분리형효소 - 면역센서
公开(公告)号：KR100455907B1
公开(公告)日：2004-11-12
申请号：KR1020010045720
申请日：2001-07-28
申请人： 주식회사 아이센스
发明人： 김민선 , 조호철 , 장봉화 , 최문희 , 남학현 , 차근식
IPC分类号： G01N33/53
摘要： PURPOSE: Provided is a non-separation type enzyme-immunsensor using parallel microporous electrodes which has high sensitivity and selectivity and employs no separation process by diffusion-movement through pores of microporous membrane. CONSTITUTION: The non-separation type enzyme-immunsensor comprises the parts of: an electrode connecting part(3), a microporous operating electrode, a first electrode system, a microporous auxiliary/standard electrode(5), a second electrode system, and a multiporous membrane(4), and is characterized by laminating a different pad having a different function according to analysates on the microporous electrode.
摘要翻译：目的：提供一种使用平行微孔电极的非分离型酶免疫传感器，其具有高灵敏度和高选择性，并且不通过在微孔膜的孔中的扩散运动进行分离过程。构成：非分离型酶免疫传感器包括以下部分：电极连接部分（3），微孔工作电极，第一电极系统，微孔辅助/标准电极（5），第二电极系统和多孔膜（4），其特征在于，根据分析物在微孔电极上层叠具有不同功能的不同垫。

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