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91. 发明公开

KR1020080020643A 아이소플라본 나노입자 및 그의 용도 有权
标题翻译： ISOFLAVONE NANOPARTICLES及其应用
公开(公告)号：KR1020080020643A
公开(公告)日：2008-03-05
申请号：KR1020077030532
申请日：2006-01-31
申请人： 디에스엠 아이피 어셋츠 비.브이.
发明人： 볼하르드트유르겐에이치 , 메일란필리뻬엠마뉴엘 , 보이머라파엘 , 첸차이-쳉 , 구츠빌러하인즈 , 제디에른스트
IPC分类号： A61K8/64 , A61K8/14
CPC分类号： A61K31/352 , A23K20/121 , A23L33/105 , A23V2002/00 , A23V2200/25 , A61K8/498 , A61K8/732 , A61K9/10 , A61K9/107 , A61K9/146 , A61K9/5161 , A61K2800/413 , A61Q19/00 , B82Y5/00 , Y10S977/773 , A23V2200/254 , A23V2250/21172 , A23V2250/2116
摘要： The present invention is directed to isoflavone nanoparticle compositions comprising isoflavone in the form of nanoparticles and preferably a carrier. The isoflavone nanoparticle compositions are particularly useful for preparing cosmetic compositions, pharmaceutical compositions, foodstuff, food and feed additives. In the compositions comprising the isoflavone nanoparticle compositions recrystallization of the isoflavone to bigger particles is retarded. ® KIPO & WIPO 2008
摘要翻译：本发明涉及包含纳米颗粒形式的异黄酮和优选载体的异黄酮纳米颗粒组合物。异黄酮纳米颗粒组合物特别可用于制备化妆品组合物，药物组合物，食品，食品和饲料添加剂。在包含异黄酮纳米颗粒组合物的组合物中，异黄酮对较大颗粒的重结晶被延迟。 ®KIPO＆WIPO 2008

92. 发明授权

KR100807142B1 엘라그산의 수분산액 및 그의 화장 용도 有权
标题翻译：乙酸的水分散度及其化妆品的使用
公开(公告)号：KR100807142B1
公开(公告)日：2008-02-27
申请号：KR1020060115882
申请日：2006-11-22
申请人： 로레알
发明人： 슈발리에베로니끄 , 케르모르방세실
IPC分类号： A61K8/04 , A61K8/90
CPC分类号： A61K8/498 , A61K8/90 , A61Q19/00 , A61Q19/02
摘要： 본 발명은, 폴리에틸렌 글리콜 블록과 폴리프로필렌 글리콜 블록으로 이루어진 공중합체에서 선택되는 비이온성 계면활성제를 포함하는, 엘라그산 또는 그의 염 또는 그의 에스테르의 수분산액에 관한 것이다.
본 발명은 또한 상기 수분산액을 포함하는 화장 또는 피부과용 조성물, 및 피부 처리를 위한, 특히 피부 탈색소화을 위한 화장 방법에 관한 것이다.

93. 发明公开

KR1020080014145A 기능성 음료 및 조성물 失效
标题翻译：生理功能饮料和组合物
公开(公告)号：KR1020080014145A
公开(公告)日：2008-02-13
申请号：KR1020087000171
申请日：2005-02-04
申请人： 아사히인료 가부시키가이샤 , 아사히 그룹 홀딩스 가부시키가이샤 , 고쿠리츠겐큐가이하츠호징 노우교 · 쇼쿠힝 산교기쥬츠 소고겐큐기코
发明人： 나가이히로시 , 야스에마사아키 , 야마모토마리
IPC分类号： A23L2/38
CPC分类号： A23F3/163 , A23F3/16 , A23L2/52 , A23L33/11 , A23L33/30 , A61K8/498 , A61K9/0095 , A61K31/353 , A61Q1/02 , A61Q19/00 , A61Q19/06 , A61Q19/10 , C07D311/62
摘要： The invention provides physiologically functional drinks and compositions which can prevent allergic rhinitis and are useful in the prevention and treatment of hyperlipemia and diseases derived therefrom such as arteriosclerosis, obesity, and liver diseases. The drinks and compositions contain as the preventive for allergic rhinitis or the antihyperlipemic agent methylated catechins represented by the general formula (1) in effective doses: wherein R1, R2, R3 and R4 are each independently hydrogen or methyl; and X1 and X2 are each independently hydrogen or hydroxy.
摘要翻译：本发明提供能够预防过敏性鼻炎的生理功能饮料和组合物，并且可用于预防和治疗高脂血症及其衍生的疾病，例如动脉硬化，肥胖症和肝脏疾病。饮料和组合物以有效剂量包含作为过敏性鼻炎的预防剂或由通式（1）表示的抗高血脂剂甲基化儿茶素类：其中R1，R2，R3和R4各自独立地为氢或甲基; 且X 1和X 2各自独立地为氢或羟基。

94. 发明公开

KR1020070120906A 백모증 처리를 위한 엘라그산의 용도 有权
标题翻译：用途用于治疗慢性乙型肝炎
公开(公告)号：KR1020070120906A
公开(公告)日：2007-12-26
申请号：KR1020070060436
申请日：2007-06-20
申请人： 로레알
发明人： 꼬모스테판
IPC分类号： A61K31/366 , A61K8/36
CPC分类号： A61K8/498 , A61Q5/065
摘要： An ellagic acid, a salt thereof, a metallic complex thereof, a mono- or poly-ether derivative thereof, a mono- or poly-acyl derivative thereof and a carbonate derivative or carbamate thereof derived from hydroxyl are provided to prevent, limit or stop the progress of canities, and maintain or promote natural re-pigmentation of hair. A cosmetic composition comprises at least one selected from the group consisting of ellagic acid, a salt thereof, a metallic complex thereof, a mono- or poly-ether derivative thereof, a mono- or poly-acyl derivative thereof and a carbonate derivative or carbamate thereof derived from hydroxyl, an agent for controlling desquamating scalp such as selenium disulfide, climbazole, undecylenic acid, ketoconazole, piroctone olamine, and cyclo piroctone, and/or a plant extract having propigmenting activity in a cosmetically acceptable medium. A method for cosmetically treating canities comprises a step of orally administering at least one compound selected from the group consisting of ellagic acid, a salt thereof, a metallic complex thereof, a mono- or poly-ether derivative thereof, a mono- or poly-acyl derivative thereof and a carbonate derivative or carbamate thereof derived from hydroxyl or topically applying the compound to a portion in need thereof.
摘要翻译：提供鞣花酸，其盐，其金属络合物，其单醚或多醚衍生物，其衍生自羟基的单酰基或多酰基衍生物和碳酸酯衍生物或氨基甲酸酯，以防止，限制或停止保护或促进头发的自然再色素沉淀。化妆品组合物包含选自鞣花酸，其盐，其金属络合物，其单醚或聚醚衍生物，其单 - 或多酰基衍生物和碳酸酯衍生物或氨基甲酸酯中的至少一种衍生自羟基的化合物，用于控制脱屑性头皮的药剂如二硫化硒，攀摩唑，十一碳烯酸，酮康唑，吡罗酮醇和环焦糖，和/或在化妆品可接受的培养基中具有辅助活性的植物提取物。美容治疗方法的方法包括口服给予选自鞣花酸，其盐，其金属络合物，其一元或多醚衍生物，单 - 或多 - 酰基衍生物和衍生自羟基的碳酸酯衍生物或氨基甲酸酯，或将化合物局部施用于有需要的部分。

95. 发明公开

KR1020070116026A 피부 미백 방법, 조성물 및 제품 无效
标题翻译：皮肤照射方法，组合物和产品
公开(公告)号：KR1020070116026A
公开(公告)日：2007-12-06
申请号：KR1020077022106
申请日：2006-03-17
申请人： 지보당 에스아
发明人： 나츠쉬안드레아스 , 와세샤미카엘
IPC分类号： A61K8/35 , A61K8/33 , A61K8/34 , A61Q19/02
CPC分类号： A61K8/34 , A61K8/33 , A61K8/347 , A61K8/35 , A61K8/40 , A61K8/411 , A61K8/4973 , A61K8/498 , A61Q13/00 , A61Q19/02
摘要： The invention relates to methods of cosmetic lightening the human skin, compounds and perfume compositions that have a skin lightening effect and personal care products for application to the human skin comprising such skin lightening compounds and perfume compositions. A number of compounds not known before to have a skin lightening effect were identified. These skin lightening compounds provide the perfumer with a larger palette of fragrance notes and provide more possibilities to create desired fragrance accords in skin lightening perfume compositions and skin lightening personal care products. Skin lightening perfume compositions and skin lightening personal care products according to the invention comprise at least one of the identified fragrant skin lightening compounds.
摘要翻译：本发明涉及化妆品化妆品的化妆品，其具有皮肤增亮效果的化妆品，化妆品和香料组合物以及用于人皮肤的个人护理产品，其包含这些皮肤增亮化合物和香料组合物。鉴定了许多以前不知道具有皮肤增亮作用的化合物。这些皮肤增亮化合物为香料师提供了更大的香味调色剂，并提供更多的可能性，以在皮肤增亮香水组合物和皮肤增亮个人护理产品中产生所需的香料。根据本发明的皮肤增亮香水组合物和皮肤增亮个人护理产品包含至少一种所鉴定的香味皮肤发亮化合物。

96. 发明公开

KR1020070112383A 테르페노이드 화합물을 포함하는 모발 및/또는 두피 관리조성물 无效
标题翻译：包含化合物的头发和/或护肤组合物
公开(公告)号：KR1020070112383A
公开(公告)日：2007-11-23
申请号：KR1020077020825
申请日：2006-02-21
申请人： 유니레버 엔.브이.
发明人： 보갈,란지트 , 추,자스빈 , 멜드룸,헬렌
IPC分类号： A61K8/49 , A61Q5/00
CPC分类号： A61Q5/006 , A61K8/498
摘要： The invention provides a hair and/or scalp care composition comprising a terpenoid compound of formula (I), (II) or (III) in which R1 to R11 are each, independently, -H,-F,-Cl,-Br,-I,-OH, lower alkyl (e.g. C1-6 alkyl) or lower alkoxy (e.g. C1-6 alkoxy).
摘要翻译：本发明提供包含式（I），（II）或（III）的萜类化合物的头发和/或头皮护理组合物，其中R 1至R 11各自独立地为-H，-F，-Cl，-Br， -I，-OH，低级烷基（例如C 1-6烷基）或低级烷氧基（例如C 1-6烷氧基）。

97. 发明公开

KR1020070110040A 프로안토시아니딘 올리고머의 제조방법 有权
标题翻译：低聚物中制备蒽醌的方法
公开(公告)号：KR1020070110040A
公开(公告)日：2007-11-15
申请号：KR1020077019349
申请日：2006-02-24
申请人： 고쿠리츠다이가쿠호진 나가사키다이가쿠 , 우사이엔 세이야꾸 가부시키가이샤 , 가부시키가이샤 아미노 압 가가쿠
发明人： 다나카타카시 , 노나카겐이치로 , 코노이사오 , 후지이하지메 , 나카가와타카시 , 니시오카히로시
IPC分类号： A61K31/353 , C07D407/14 , A61P25/00 , A61P39/06
CPC分类号： A61K31/353 , A61K8/498 , A61K36/04 , A61K36/14 , A61K36/15 , A61K36/185 , A61K36/45 , A61K36/485 , A61K36/54 , A61K36/61 , A61K36/73 , A61K36/734 , A61K36/74 , A61K36/77 , A61K36/82 , A61K36/87 , A61K36/88 , A61K36/889 , A61K2800/522 , A61Q19/08 , C07D311/62 , A61K2300/00
摘要： A composition containing, as the main component, a proanthocyanidin oligomer which is obtained by heating a plant material containing a proanthocyanidin polymer or its extract together with a substance having a phloroglucinol ring or resorcinol ring structure in an acidic solution, carries the substance having the fluoro/resorcinol ring structure attached thereto and has been degraded; a method of producing the same; and use of the composition in health foods, drugs and so on. Thus, the proanthocyanidin oligomer having a biological activity, carrying the substance having a phloroglucinol ring or resorcinol ring structure attached to the terminus thereof and having been degraded to a level allowing the absorption in vivo, which can be hardly obtained from a plant material at a high yield, can be efficiently and easily obtained.
摘要翻译：以含有原花色素聚合物或其提取物的植物材料以及含有间苯三酚环或间苯二酚环结构的物质在酸性溶液中加热得到的原花青素低聚物作为主要成分的组合物携带具有氟原子的物质 /间苯二酚环结构，并且已经降解; 其制造方法; 并在保健食品，药物等方面使用组合物。因此，具有生物活性的原花青素低聚物，其携带具有间苯三酚环或间苯二酚环结构的物质，其附着于其末端并已降解至允许体内吸收的水平，这几乎不能从植物材料获得高产率，可以有效且容易地获得。

98. 发明授权

KR100768362B1 치환 아민 유도체를 포함하는 미용 조성물 失效
标题翻译：含有取代胺衍生物的化妆品组合物
公开(公告)号：KR100768362B1
公开(公告)日：2007-10-18
申请号：KR1020027017957
申请日：2001-06-05
申请人： 유니레버 엔.브이.
发明人： 베이저,존,스티븐 , 포칼리코,데이비드,죠세프
IPC分类号： A61K8/41 , A61Q19/00
CPC分类号： A61K8/671 , A61K8/33 , A61K8/35 , A61K8/41 , A61K8/46 , A61K8/4913 , A61K8/4926 , A61K8/498 , A61Q5/00 , A61Q5/008 , A61Q5/02 , A61Q19/00 , A61Q19/008
摘要： Cosmetic methods and compositions containing selected substituted secondary amine aromatic compounds. The inventive compositions provide control of sebum secretion from sebocytes, improved oil control and improved feel, and prevent shine and stickiness.

99. 发明公开

KR1020070056674A 이카린의 가수분해물을 함유하는 화장료용 조성물 有权
标题翻译：含有ICARIIN水解物的化妆品组合物
公开(公告)号：KR1020070056674A
公开(公告)日：2007-06-04
申请号：KR1020050115649
申请日：2005-11-30
申请人： (주)아모레퍼시픽
发明人： 박준성 , 노호식 , 김덕희 , 장이섭
IPC分类号： A61K8/49 , A61Q19/10 , A61Q19/02
CPC分类号： A61K8/498 , A61K8/602 , A61K2800/522 , A61Q19/02 , A61Q19/08
摘要： A cosmetic composition comprising a hydrolysate of icariin is provided to show anti-aging effect and melanogenesis inhibition effect through expression inhibition effect, and whitening effect through improving pigmentation generated by UV, thereby being usefully used as a cosmetic composition or a pharmaceutical composition for anti-aging, whitening and wrinkle improving. The cosmetic composition comprises a hydrolysate of icariin represented by the formula(1), wherein R1 is OH or rhamnopyranose and R2 is OH or glucopyranose, provided that both R1 and R2 are not simultaneously rhamnopyranose and glucopyranose. The hydrolysate of icariin is prepared by extracting a plant using water or an organic solvent to obtain a plant extract and then hydrolyzing the plant extract using an acid, a base, an enzyme or a microorganism producing the enzyme.
摘要翻译：提供含有淫羊藿苷水解产物的化妆品组合物，以通过表达抑制作用显示出抗衰老作用和黑素生成抑制作用，以及通过改善由UV产生的色素沉着的美白效果，从而可有效地用作化妆品组合物或抗癌药物组合物，老化，美白和皱纹改善。化妆品组合物包含由式（1）表示的淫羊a a水解物，其中R1是OH或吡喃糖吡喃糖，R2是OH或吡喃葡萄糖，条件是R1和R2都不是同时具有吡喃葡萄糖和吡喃葡萄糖。通过使用水或有机溶剂提取植物来获得植物提取物，然后使用产生该酶的酸，碱，酶或微生物水解植物提取物来制备淫羊茸的水解产物。

100. 发明公开

KR1020070026590A 메로시아닌 유도체 无效
标题翻译：月桂酰胺衍生物
公开(公告)号：KR1020070026590A
公开(公告)日：2007-03-08
申请号：KR1020067026302
申请日：2005-06-20
申请人： 시바 홀딩 인코포레이티드
发明人： 바그너바르바라 , 비에네발트프랑크 , 볼레프하인츠 , 발퀴스트올로프 , 헤르조크베른트 , 엘리스토마스 , 하제쥐르크
IPC分类号： A61K8/81 , A61Q17/04
CPC分类号： A61K8/498 , A61K8/4913 , A61K8/494 , A61Q17/04
摘要： Disclosed is the use of merocyanine derivatives of formula (I), wherein Q is hydrogen; C1-C22alkyl; -OH; -OR7; -NR7R8; or -N=R9; R1 is hydrogen; C1-C22alkyl; -OR7, -SR7; -NR7R8; C1-C22alkyl; C2-C12alkenyl; C2-C12alkinyl; C3-C12cycloalkyl; C3-C12cycloalkenyl; C7-C12aralkyl; C1-C12heteroalkyl, C2-C11heteroaralkyl; C6-C10aryl; or C1-C9heteroaryl; R4 is cyano; COR7, COOR7; CONR7R8; SO2(C6-C12)aryl; C2-C12alk-1-enyl; C3-C12cycloalk-1-enyl; C2-C12alk-1-inyl; C2-C12heteroalkyl; C3-C5heterocycloalkyl; C6-C10aryl; or C1-C9heteroaryl; R5 is -COR7; -COOR7; -OR7; -SR7, -NHR7, -NR7R8; C1-C22alkyl; C2-C12alkenyl; C2-C12alkinyl; C3-C12cycloalkyl; C3-C12cycloalkenyl; C7-C12aralkyl; C1-C12alkylphenyl; C1-C12alkoxy-C6-C10aryl; C1-C12heteroalkyl; C2-C11heteroaralkyl; C3-C12cycloheteroalkyl; C6-C10aryl; C1- C12alkoxy-C6-C10aryl; or C1-C9heteroaryl; R6 is hydrogen; C1-C22alkyl; C1-C22alkoxy; or COR7; R7 and R8 independently from each other are hydrogen; C1-C22alkyl; C2-C12alkenyl; C2-C12alkinyl; C3-C12cycloalkyl; C3-C12cycloalkenyl; -(CH2)tCOOH; C7-C12aralkyl; C1-C12heteroalkyl; C2-C11heteroaralkyl; C6-C10aryl; C1-C9heteroaryl; Si-R10R11R12; Si(OR10)(OR11)(OR12); SiR10(OR11)(OR12); SiR10R11(OR12); -(CH2)u-O-(CH2)v-SiR10R11R12; or a radical X-Sil; t, u and v, independently from each other are a number from 1 to 5; R9 is a (C1-C6)alkylidene radical; R10, R11, R12 independently form each other are C1-C22alkyl; X is a linker; Sil is a silane-, oligosiloxane- or polysiloxane radical; R1 and R2, R1 and Q, R1 and R6, R1 and T, R2 and R3, R2 and R4, R2 and R6, R2 and Q, R4 and R6, R4 and T, R6 and Q, T and Q, each independently, are linked together, so that 1, 2, 3 or 4 carbocyclic or N, O and/or S-heterocyclic rings are formed, wherein each of them, independently from each other, may be condensed with an aromatic or heteroaromatic ring, and/or more N-, O- and/or S-heterocyclic rings, and each N atom in a N-heterocyclic ring may be substituted by C1-C22alkyl; n is a number from 1 to 4; wherein at least one of the radicals R1, R6 or Q is different from hydrogen; if n = 1 T is -COR5; -CN; C6-C10aryl; -NHR5; or -SO2-(C6-C12)aryl; R2 and R3 independently from each other are C1-C22alkyl; hydroxy-C1-C22alkyl; C2-C12alkenyl; C2-C12alkinyl; C3-C12cycloalkyl, C3-C12cycloalkenyl; C7-C12aralkyl; C1-C12heteroalkyl; C3-C12cycloheteroalkyl; C6-C10aryl; C1-C9heteroaryl; or a radical of formula (II); p is a number from 5 to 100; q is a number from 1 to 5; s is a number from 0 to 4; if n = 2 R2 and R3 are each C1-C5alkylene; and simultaneously T is defined as for n = 1; or T is a bivalent radical of formula -NR7-V-NR7-, wherin V is phenylene; or C1-C5alkylene; R7 is hydrogen; or C1-C5alkyl; and R2 and R3 simultaneously are defined as for n = 1; if n = 3 one of R2, R3 or T is a trivalent radical; if n = 4 one of R2, R3 or T is a tetravalent radical; for protecting of human hair and skin against the damaging effect of UV radiation. ® KIPO & WIPO 2007
摘要翻译：公开了式（I）的部花青衍生物的用途，其中Q是氢; C1-C22烷基; -哦; -OR7; -NR7R8; 或-N = R 9; R1是氢; C1-C22烷基; -OR7，-SR7; -NR7R8; C1-C22烷基; C2--C 12烯; C2-C12alkinyl; C3-C12环烷基; C3-C12cycloalkenyl; C7-C12aralkyl; C 1 -C 12杂烷基，C 2 -C 11杂芳烷基; C6-C10芳基; 或C 1 -C 9杂芳基; R4是氰基; COR7，COOR7; CONR7R8; SO2（C6-C12）芳基; C2-C12alk -1-烯基; C3-C12cycloalk -1-烯基; C2-C12alk -1-炔; C2-C12heteroalkyl; C3-C5heterocycloalkyl; C6-C10芳基; 或C 1 -C 9杂芳基; R5为-COR7; -COOR7; -OR7; -SR 7，-NHR 7，-NR 7 R 8; C1-C22烷基; C2--C 12烯; C2-C12alkinyl; C3-C12环烷基; C3-C12cycloalkenyl; C7-C12aralkyl; C1-C12alkylphenyl; C1-C12烷氧基，C6-C10芳基; C1-C12heteroalkyl; C2-C11heteroaralkyl; C3-C12cycloheteroalkyl; C6-C10芳基; C 1 -C 12烷氧基-C 6 -C 10芳基; 或C 1 -C 9杂芳基; R6是氢; C1-C22烷基; C1-C22alkoxy; 或COR7; R 7和R 8彼此独立地是氢; C1-C22烷基; C2--C 12烯; C2-C12alkinyl; C3-C12环烷基; C3-C12cycloalkenyl; - （CH2）tCOOH; C7-C12aralkyl; C1-C12heteroalkyl; C2-C11heteroaralkyl; C6-C10芳基; C1-C9heteroaryl; 的Si-R10R11R12; 的Si（OR 10）（OR 11）（OR 12）; SiR10（OR11）（OR12）; SiR10R11（OR12）; - （CH 2）u-O-（CH 2）V-SiR10R11R12; 或基团X-Sil; t，u和v彼此独立地为1至5的数; R9是（C1-C6）亚烷基; R 10，R 11，R 12彼此独立地为C 1 -C 22烷基; X是一个连接子; Sil是硅烷，低聚硅氧烷或聚硅氧烷基团; R1和R2，R1和Q，R1和R6，R1和T，R2和R3，R2和R4，R2和R6，R2和Q，R4和R6，R4和T，R6和Q，T和Q各自独立形成1,2或3或4个碳环或N，O和/或S-杂环，其中它们彼此独立地可以与芳族或杂芳族环稠合，并且 /或更多的N，O-和/或S-杂环，并且N-杂环中的每个N原子可以被C 1 -C 22烷基取代; n是从1到4的数字; 其中基团R1，R6或Q中的至少一个不同于氢; 如果n = 1，则T为-COR 5; -CN; C6-C10芳基; -NHR 5; 或-SO 2 - （C 6 -C 12）芳基; R2和R3彼此独立地为C1-C22烷基; 羟基C1-C22烷基; C2--C 12烯; C2-C12alkinyl; C3-C12环烷基，C3-C12环烯基; C7-C12aralkyl; C1-C12heteroalkyl; C3-C12cycloheteroalkyl; C6-C10芳基; C1-C9heteroaryl; 或式（II）的基团; p是从5到100的数字; q是从1到5的数字; s是从0到4的数字; 如果n = 2，R 2和R 3各自为C 1 -C 5亚烷基; 并且同时T定义为n = 1; 或T是式-NR7-V-NR7-的二价基团，V是亚苯基; 或C 1 -C 5亚烷基; R7是氢; 或C 1 -C 5烷基; R2和R3同时定义为n = 1; 如果n = 3，R 2或R 3中的一个为三价基团; 如果n = 4，R2，R3或T是四价基团; 用于保护人的头发和皮肤免受紫外线辐射的破坏作用。 ®KIPO＆WIPO 2007

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