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    • 9. 发明公开
    • 제대혈로부터 분리 또는 증식된 세포를 포함하는 발달성,만성 폐질환 치료용 조성물
    • 用于治疗包含从脐带血分离或增殖的细胞的发育和/或慢性肺损伤的组合物
    • KR1020070079316A
    • 2007-08-06
    • KR1020070010191
    • 2007-01-31
    • 사회복지법인 삼성생명공익재단메디포스트(주)
    • 장윤실박원순양윤선
    • A61K35/14A61P11/00
    • A61K35/28A61K35/16A61K35/51A61K45/06A61K2300/00
    • A therapeutic composition comprising cells separated or proliferated from umbilical cord blood is provided to be intratracheally administered so as to effectively treat developmental and/or chronic lung diseases. The composition for treating developmental or chronic lung diseases comprises cells separated or proliferated from umbilical cord blood as an effective ingredient, wherein the cells are selected from the group consisting of monocytes separated from the umbilical cord blood, mesenchymal stem cells separated from the umbilical cord blood, mesenchymal stem cells amplified from the mesenchymal stem cell by sub-culture, and a mixture thereof. The composition further comprises an auxiliary component selected from the group consisting of a culture medium, a gene effective in the treatment of lung disease or an expression vector comprising the same, a cytokine providing autocrine or paracrine effect, a growth factor, and a combination thereof.
    • 提供包含从脐带血分离或增殖的细胞的治疗组合物以气管内施用,以有效治疗发育和/或慢性肺部疾病。 用于治疗发育性或慢性肺疾病的组合物包括从脐带血分离或增殖的细胞作为有效成分,其中所述细胞选自从脐带血分离的单核细胞,从脐带血分离的间充质干细胞 ,通过亚培养从间充质干细胞扩增的间充质干细胞及其混合物。 组合物还包含选自培养基,有效治疗肺部疾病的基因或含有该疾病的表达载体,提供自分泌或旁分泌作用的细胞因子,生长因子及其组合的辅助成分 。