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    • 9. 发明专利
    • Method for producing and refining cordycepin
    • 生产和精制CORDYCEPIN的方法
    • JP2013111060A
    • 2013-06-10
    • JP2011262995
    • 2011-11-30
    • Univ Of Fukui国立大学法人福井大学
    • SAKURAI AKIHIKOMASUDA MINA
    • C12P19/32
    • PROBLEM TO BE SOLVED: To provide a method for easily and efficiently producing cordycepin of high purity, and a method for easily separating and refining cordycepin at a high recovery rate.SOLUTION: Cordycepin is produced at a high concentration in a culture solution by culturing cordyceps using a filtrated and sterilized culture solution. The cordycepin is separated and refined at a high purity and at the high recovery rate by crystallization based on a temperature change and a pH change from a culture supernatant fluid separated from the obtained culture solution.
    • 要解决的问题:提供一种容易高效地生产高纯度虫草素的方法,以及以高回收率容易地分离和精制虫草素的方法。 解决方案:使用过滤和灭菌的培养溶液培养冬虫夏草,在培养溶液中以高浓度产生虫草素。 通过基于从获得的培养液中分离的培养上清液的温度变化和pH变化而结晶,以高纯度和高回收率分离和精制虫草素。 版权所有(C)2013,JPO&INPIT