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1. 发明专利

JP2010150256A Cosmetic and/or dermatological composition based on n,n'-diarylmethylene ethylenediamine diacetic ester 审中-公开
标题翻译：基于N，N'-二甲基乙烯乙酰胺二胺的化妆和/或皮肤组成
公开(公告)号：JP2010150256A
公开(公告)日：2010-07-08
申请号：JP2009283254
申请日：2009-12-14
申请人： L'oreal Sa , ロレアルL′Oreal
发明人： KERMORVAN CECILE , CHEVALIER VERONIQUE
IPC分类号： A61K8/44 , A61K8/06 , A61Q1/00 , A61Q19/00 , A61Q19/08 , C07C229/04
CPC分类号： A61K8/44 , A61K8/37 , A61K8/4973 , A61Q19/08
摘要： PROBLEM TO BE SOLVED: To provide a composition in which an N,N'-diarylmethylene ethylenediamine diacetic ester useful for preventing aging of skin with ultraviolet light is dissolved in a specific solvent, and the dissolution thereof is maintained over a long period of time. SOLUTION: The cosmetic and/or dermatological composition includes (a) at least one compound based on the N,N'-diarylmethylene ethylenediamine diacetic ester; and (b) an effective amount of at least one solvent which is a solvent selected from among (i) isononyl isononanoate; (ii) dimethyl isosorbide; (iii) an amino acid ester represented by formula (II); and (iv) a mixture thereof in a physiologically acceptable medium containing at least one oil. COPYRIGHT: (C)2010,JPO&INPIT
摘要翻译：待解决的问题：提供一种组合物，其中可用于防止紫外线老化的N，N'-二芳基亚甲基乙二胺二乙酸酯溶于特定溶剂中，并且其溶解长时间保持的时间。化妆品和/或皮肤病学组合物包括（a）至少一种基于N，N'-二芳基亚甲基乙二胺二乙酸酯的化合物; 和（b）有效量的至少一种溶剂，其是选自（i）异壬酸异壬酯的溶剂; （ii）二甲基异山梨醇酯; （iii）由式（II）表示的氨基酸酯; 和（iv）其在含有至少一种油的生理学可接受的介质中的混合物。版权所有（C）2010，JPO＆INPIT

3. 发明专利

JPH10259175A N-ACYL-HYDROXYAMINO ACID ESTER AND ITS USE 失效
公开(公告)号：JPH10259175A
公开(公告)日：1998-09-29
申请号：JP7309198
申请日：1998-03-09
申请人： HAARMANN & REIMER GMBH
发明人： LEY JAKOB , LANGNER ROLAND
IPC分类号： A61K8/00 , A61K8/44 , A61K8/49 , A61K8/68 , A61K31/195 , A61Q5/00 , A61Q5/02 , A61Q17/00 , A61Q19/00 , C07C229/04 , C07C229/22 , C07C231/02 , C07C233/47 , C07D207/16 , C07D211/60 , C07D223/06 , A61K7/06 , A61K7/40 , A61K7/48
摘要： PROBLEM TO BE SOLVED: To easily obtain the subject new compound as a new pseudobiocompound having ceramide-like action from a natural stock. SOLUTION: This new compound is expressed by formula I [R is a 5-50C (hydroxyl-substituted) alkyl or alkenyl; R is a 1-49C (hydroxyl-substituted) alkyl or alkenyl; Y and Y are each H or OH; R and R are each H, a 1-10C alkyl or alkenyl, or joined together into a 1-3C (substituted) alkylene, forming a heterocycle together with a chain lying therebetween], e.g. trans-4-hydroxy-l- proline 1-dodecyl ester. The compound of formula I is obtained by esterifying a hydroxyamino acid (salt) of formula II by the aid of an alcohol of the formula R -OH to form an intermediate of formula III or formula IV (A is an inorganic or organic anion) which in turn is condensed with a compound of the formula R -COX (X is hydroxy, a halogen, etc.).

4. 发明专利

JPH07330737A BACTERICIDAL OPTICALLY ACTIVE 2-IMIDAZOLIN-5-ONE AND 2-IMIDAZOLINE-5-THION DERIVATIVES 失效
公开(公告)号：JPH07330737A
公开(公告)日：1995-12-19
申请号：JP13561294
申请日：1994-06-17
申请人： RHONE POULENC AGROCHIMIE
发明人： JIYANNFUIRITSUPU BASUKU , ARAN GADOURA , GI RAKUROA , JIYOZEFU PERE
IPC分类号： A01N43/50 , A01P3/00 , C07C229/04 , C07C229/36 , C07C243/32 , C07C243/34 , C07C291/00 , C07C331/18 , C07C331/24 , C07D20060101 , C07D233/70 , C07D233/72 , C07D233/74 , C07D233/76 , C07D233/78 , C07D233/80 , C07D233/84 , C07D233/86 , C07D235/02 , C07D263/42 , C07D401/04 , C07D401/12 , C07D401/14 , C07D403/04 , C07D403/12 , C07D403/14 , C07D405/04 , C07D405/12 , C07D405/14 , C07D409/04 , C07D409/12 , C07D409/14 , C07D413/12 , C07D413/14 , C07D417/12
摘要： 1. Optically active derivatives of 2-imidazolin-5-ones and 2-imidazoline-5-thiones. 2. They are of general formula I: with M = O, S or optionally halogenated CH2 W = O, S or S=O p = 0 or 1 R , R and R are a hydrocarbon radical, especially an aryl radical, which is optionally substituted, especially by halogen atoms R is H or optionally halogenated C1-C2 alkyl R is a hydrocarbon radical. 3. Use as agricultural fungicides.

5. 发明专利

JPS61189267A SEPARATION OF TRYPTOPHAN 失效
公开(公告)号：JPS61189267A
公开(公告)日：1986-08-22
申请号：JP2996285
申请日：1985-02-18
申请人： LIGHT OIL UTILIZATION RES ASS
发明人： HOYA TAKAO , MOGI HIDENOBU , HAYAYAMA HIROSHI
IPC分类号： C07D209/20 , C07C67/00 , C07C227/00 , C07C227/40 , C07C229/04
摘要： PURPOSE:To obtain tryptophan from an aqueous solution containing tryptophan together with other amino acids, by contacting the solution with a strongly acidic cation exchange resin beads, desorbing the other amino acids from the resin with an aqueous solution of an acid, etc., and then separating tryptophan with an alkaline aqueous solution. CONSTITUTION:An aqueous solution containing tryptophan together with other amino acids is made to contact with strongly acidic cation exchange resin beads filled in a column to effect the adsorption of tryptophan and a part of the coexisting amino acids, and the resin is made to contact with an aqueous solution of an acid or an inorganic salt to effect the desorption of the adsorbed coexisting amino acids. Thereafter, the adsorbed tryptophan is desorbed with an alkaline aqueous solution, and the desorbed solution is made to contact again with the resin. The adsorption and desorption are repeated to separate the tryptophan in the form of highly concentrated solution. EFFECT:An alkaline aqueous solution having a tryptophan concentration of 3-15wt% and free from impurity amino acid can be produced.

6. 发明专利

JPS61183253A NOVEL PEPTIDASE INHIBITOR 失效
公开(公告)号：JPS61183253A
公开(公告)日：1986-08-15
申请号：JP2137186
申请日：1986-02-04
申请人： MERRELL DOW PHARMA
发明人： MAIKERU KORUBU , MAIKERU JIEI JIYANGU , JIYOSEFU PII BURUKAATO , FURITSUTSU II GEEHAATO , YUUJIN ERU GIROTSUKUSU , DANIERU JII SUCHIRURIN , BAANAADO NEISESU
IPC分类号： C07K5/00 , A61K31/13 , A61K31/16 , A61K31/165 , A61K31/195 , A61K31/215 , A61K31/22 , A61K38/00 , A61K38/55 , A61P7/02 , A61P7/06 , A61P9/12 , A61P13/02 , A61P15/00 , A61P17/00 , A61P29/00 , A61P31/04 , A61P35/00 , A61P43/00 , C07C67/00 , C07C213/00 , C07C221/00 , C07C225/02 , C07C225/16 , C07C227/00 , C07C227/16 , C07C227/18 , C07C229/02 , C07C229/04 , C07C229/22 , C07C229/24 , C07C229/26 , C07C233/01 , C07C233/31 , C07C237/02 , C07C237/06 , C07C237/12 , C07C237/20 , C07C237/22 , C07C239/00 , C07C271/06 , C07C271/22 , C07C273/04 , C07C279/18 , C07D207/16 , C07D209/42 , C07D498/10 , C07K1/113 , C07K5/02 , C07K5/04 , C07K5/06 , C07K5/062 , C07K5/08 , C07K5/083 , C07K5/097 , C07K7/06 , C07K14/81 , C12N9/99
摘要： This invention relates to analogs of peptidase substrates in which the amide group containing the scissile amide bond of the substrate peptide has been replaced by an activated electrophilic ketone moiety. These analogs of the peptidase substrates provide specific enzyme inhibitors for a variety of proteases, the inhibition of which will have useful physiological consequences in a variety of disease states.

7. 发明专利

JPS56122386A NOVEL PYRIDOXAMINE COMPOUND AND ITS PREPARATION 失效
公开(公告)号：JPS56122386A
公开(公告)日：1981-09-25
申请号：JP2638280
申请日：1980-03-03
申请人： RIKAGAKU KENKYUSHO
发明人： KUZUHARA HIROMI , ANDOU MAKOTO
IPC分类号： C07D513/08 , C07C227/04 , C07C229/04
摘要： NEW MATERIAL:A pyridoxamine compound shown by the formula I. EXAMPLE:( + or - )-15-Aminomethyl-14-hydroxy-5,5-dimethyl-2,8-dithia[9]( 2,5 )pyridinophane. USE:A reagent for synthesizing an optical active amino acid. Having high stereoselectivity. The possibility to prepare by products is lost, purification by distillation is possible, purification operation is easy, and a large amount of handling can be carried out. PROCESS:A pyridinophane shown by the formula II is treated with a hydroxylamine hydrochloride in the presence of a base, to give an oxime compound shown by the formula III. The oxime compound shown by the formula III is reduced with NaBH4, etc., to give a pyridoxamine compound shown by the formula I.

8. 发明专利

JP2014139150A Method for producing n-acylamino acid or n-acylpeptide by using amino acid ionic liquid 有权
标题翻译：通过使用氨基酸离子液体生产N-亚氨基酸或N-乙酰胆碱的方法
公开(公告)号：JP2014139150A
公开(公告)日：2014-07-31
申请号：JP2013008763
申请日：2013-01-21
申请人： Ajinomoto Co Inc , 味の素株式会社
发明人： FURUKAWA SHINYA , HATTORI TATSUYA , NAKATANI RYOTARO , HATTORI TAKESHI
IPC分类号： C07C227/18 , A61K8/44 , A61K8/64 , A61Q11/00 , A61Q19/02 , A61Q19/08 , A61Q19/10 , C07B61/00 , C07C229/04
摘要： PROBLEM TO BE SOLVED: To provide a method for synthesizing N-acylamino acid or N-acylpeptide without using fatty acid chloride.SOLUTION: The method for producing N-acylamino acid or N-acylpeptide comprises a step of reacting ionic liquefied amino acid or peptide (A) with a fatty acid or ester thereof (B) under such a condition that a molar ratio of (A):(B) is 1:10 to 10:1.
摘要翻译：要解决的问题：提供不使用脂肪酰氯合成N-酰基氨基酸或N-酰基肽的方法。解决方案：N-酰基氨基酸或N-酰基肽的制备方法包括使离子液化氨基酸或肽（A）与脂肪酸或其酯（B）的摩尔比为1:10〜10:1的条件下进行。

9. 发明专利

JP2013199462A Method for synthesizing novel ferromagnetic organic magnetic fluid and method for using the same 有权
标题翻译：合成新型有机磁性液体的方法及其使用方法
公开(公告)号：JP2013199462A
公开(公告)日：2013-10-03
申请号：JP2012098182
申请日：2012-03-26
申请人： Hiroshi Kashihara , 宏樫原
发明人： KASHIHARA HIROSHI
IPC分类号： C07C229/08 , C07C211/03 , C07C211/11 , C07C211/14 , C07C211/65 , C07C215/12 , C07C223/02 , C07C229/04 , C07C229/22 , C07C229/24 , C07C233/05 , C07C323/60 , C07D207/10 , C07D213/55 , H01F1/00
摘要： PROBLEM TO BE SOLVED: To provide a method for synthesizing a novel ferromagnetic organic magnetic fluid and a method for using the same.SOLUTION: A ferromagnetic organic magnetic fluid has a remarkably stronger magnetism than metal salts having an original magnetism by binding various kinds of diamagnetic organic compounds to the metal salts MXn having a magnetism by a coordination bonding and an ion bonding and is shown by a formula [I] or in particular shown by a formula (A) for example. Here, M is trivalent Fe, divalent Fe, divalent Co, divalent Mn, trivalent Dy, trivalent Nd, and trivalent Sm; X is halogen atoms such as fluorine atom, chlorine atom, bromine atom, and iodine atom; and n is an integer of 2 or 3.
摘要翻译：要解决的问题：提供一种合成新型铁磁性有机磁性流体的方法及其使用方法。解决方案：铁磁性有机磁性流体与具有原始磁性的金属盐具有非常强的磁性，通过结合各种抗磁性通过配位键和离子键合具有磁性的金属盐MXn的有机化合物由式[I]表示或具体由式（A）示出。这里，M是三价Fe，二价Fe，二价Co，二价Mn，三价Dy，三价Nd和三价Sm; X是卤素原子如氟原子，氯原子，溴原子和碘原子; n为2或3的整数。

10. 发明专利

JP2013523935A Separation method 有权
公开(公告)号：JP2013523935A
公开(公告)日：2013-06-17
申请号：JP2013501881
申请日：2011-03-29
申请人：デュポンニュートリションバイオサイエンシーズエーピーエス
发明人：ユルキ・アイラクシネン , ハンヌ・パーナネン , ヤリ・レワンドウスキ , カリ・ライホ
IPC分类号： C08B37/00 , B01D15/08 , C07C227/40 , C07C229/04 , C07H3/02 , C07H3/04 , C08B30/04 , C08B37/14 , C13K13/00
CPC分类号： C13B20/148 , B01D15/185 , C07C227/40 , C13K13/00 , C07C229/12
摘要：本発明は、多成分供給液から糖類およびベタインなどの生成物を分離して回収する、３プロフィールクロマトグラフィー逐次ＳＭＢ法に関する。本発明の方法では、クロマトグラフ分離システムのいくつかの位置から、生成物画分および任意選択により再循環画分が収集される。本発明の方法は、甜菜ベース溶液からのスクロースおよびベタインの分離に、そして例えば植物ベースの加水分解物からの例えばキシロースなどの糖類の分離に応用することもできる。

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