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3. 发明专利

JP4406966B2 The fluorine-containing polyfunctional (meth) acrylic acid ester and a low refractive material 有权
$The fluorine-containing polyfunctional (meth) acrylic acid ester and a low refractive material$
公开(公告)号：JP4406966B2
公开(公告)日：2010-02-03
申请号：JP24867699
申请日：1999-09-02
申请人：凸版印刷株式会社
发明人：俊昭吉原 , 透大久保
IPC分类号： C07C69/653 , C07C271/64 , C07C269/02 , C08F20/26 , G02B1/11 , G02B1/111 , G02B6/44

5. 发明专利

JP2008266333A Benzamidine derivative having ltb4-antagonist activity, and medicinal use thereof 有权
标题翻译：具有LTB4-拮抗剂活性的苯扎明衍生物及其药物用途
公开(公告)号：JP2008266333A
公开(公告)日：2008-11-06
申请号：JP2008107036
申请日：2008-04-16
申请人： Boehringer Ingelheim Pharma Gmbh & Co Kg , ベーリンガーインゲルハイムファルマゲゼルシャフトミットベシュレンクテルハフツングウントコンパニーコマンディトゲゼルシャフト
发明人： SCHROMM KURT , ANDERSKEWITZ RALF , RENTH ERNST-OTTO , BIRKE FRANZ , JENNEWEIN HANS MICHAEL , MEADE CHRISTOPHER JOHN MONTAGU
IPC分类号： B01J25/02 , C07C257/18 , A61K31/00 , A61K31/155 , A61K31/166 , A61K31/27 , A61K31/35 , A61K31/353 , A61K31/36 , A61K31/495 , A61K31/5375 , A61P1/00 , A61P1/04 , A61P9/10 , A61P11/00 , A61P11/06 , A61P17/06 , A61P19/02 , A61P25/00 , A61P25/28 , A61P37/08 , A61P43/00 , C07B61/00 , C07C257/20 , C07C271/64 , C07D295/08 , C07D295/092 , C07D295/10 , C07D311/78 , C07D311/82 , C07D317/64
CPC分类号： C07D295/088 , C07C257/18 , C07C271/64
摘要： PROBLEM TO BE SOLVED: To provide a new benzamidine derivative, its synthetic process and the use of the derivative in a medicinal composition.
SOLUTION: The derivative is expressed by formula (1). The production method and medicinal use thereof are also provided.
COPYRIGHT: (C)2009,JPO&INPIT
摘要翻译：待解决的问题：提供新的苯甲脒衍生物，其合成方法和衍生物在药用组合物中的用途。解决方案：衍生物由式（1）表示。还提供了其制备方法和药物用途。版权所有（C）2009，JPO＆INPIT

6. 发明专利

JP2006056827A Manufacturing method of carbonyl compound 有权
标题翻译：碳化合物的制造方法
公开(公告)号：JP2006056827A
公开(公告)日：2006-03-02
申请号：JP2004240287
申请日：2004-08-20
申请人： Gifu Univ , 国立大学法人岐阜大学
发明人： SHIBAHARA FUMITOSHI , MURAI TOSHIAKI , SUETSUGU AIKO
IPC分类号： C07C231/10 , C07B61/00 , C07C233/05 , C07C233/65 , C07C235/46 , C07C269/00 , C07C271/64 , C07C273/18 , C07C275/06 , C07C333/10 , C07D239/10 , C07D295/10
摘要： PROBLEM TO BE SOLVED: To provide a manufacturing method of a carbonyl compound which permits easy manufacture of the carbonyl compound.
SOLUTION: The carbonyl compound is manufactured by reacting a thiocarbonyl compound with a molecular oxygen in a polar solvent in the presence of a catalyst comprising at least one selected from the group consisting of group 8 metals, group 9 metals, group 10 metals and group 11 metals in the periodic table. The carbonyl compound is also manufactured by reacting a selenocarbonyl compound with molecular oxygen in the presence of the above-mentioned catalyst in the polar solvent. The molecular oxygen acts as an oxidizing agent of the thiocarbonyl compound or the selenocarbonyl compound to effect the desulfurizing oxidation reaction or the deselenizing oxidation reaction.
COPYRIGHT: (C)2006,JPO&NCIPI
摘要翻译：待解决的问题：提供能够容易地制造羰基化合物的羰基化合物的制造方法。解决方案：羰基化合物通过硫代羰基化合物与分子氧在极性溶剂中在催化剂存在下反应制备，所述催化剂包含选自第8族金属，第9族金属，第10族金属中的至少一种和周期表中的第11族金属。羰基化合物也可以通过在极性溶剂中在上述催化剂存在下使硒羰基化合物与分子氧反应来制备。分子氧作为硫代羰基化合物或硒羰基化合物的氧化剂，用于脱硫氧化反应或脱硒氧化反应。版权所有（C）2006，JPO＆NCIPI

7. 发明专利

JP2005060340A Method for production of optically active beta-amino acid derivative 有权
标题翻译：光活性β-氨基酸衍生物的制备方法
公开(公告)号：JP2005060340A
公开(公告)日：2005-03-10
申请号：JP2003295599
申请日：2003-08-19
申请人： Takasago Internatl Corp , 高砂香料工業株式会社
发明人： SODEOKA MIKIKO , HAMASHIMA YOSHITAKA
IPC分类号： C07D263/22 , C07B53/00 , C07B61/00 , C07C227/32 , C07C269/06 , C07C271/20 , C07C271/64 , C07D263/26
CPC分类号： C07C269/06 , C07C227/32 , C07C271/20 , C07C271/64
摘要： PROBLEM TO BE SOLVED: To provide a method for producing a desired optically active β-amino acid derivative in high optical purity and high yield without needing a deprotection process. SOLUTION: This production method for an optically active β-amino acid derivative or its salt represented by general formula (2) comprises reacting an amine or its acid salt with an α,β-unsaturated carboxylic acid derivative or its salt represented by general formula (1) in the presence of a chiral catalyst and also in the presence or absence of an acid. COPYRIGHT: (C)2005,JPO&NCIPI
摘要翻译：要解决的问题：提供一种以高光学纯度和高产率制备所需光学活性β-氨基酸衍生物的方法，而不需要脱保护方法。解决方案：由通式（2）表示的光学活性β-氨基酸衍生物或其盐的制备方法包括使胺或其酸式盐与α，β-不饱和羧酸衍生物或其盐在通式（1）的存在下，在手性催化剂的存在下，也存在或不存在酸。版权所有（C）2005，JPO＆NCIPI

8. 发明专利

JP2001322974A 4-AMINOMETHYL-1-AMIDINOBENZENE COMPOUND 失效
公开(公告)号：JP2001322974A
公开(公告)日：2001-11-20
申请号：JP2001091958
申请日：2001-03-28
申请人： ASTRAZENECA AB
发明人： ANTONSSON KARL THOMAS , BYLUND RUTH ELVY , GUSTAFSSON NILS DAVID , NILSSON NILS OLOV INGEMAR
IPC分类号： C07D239/12 , A61K31/397 , A61K31/445 , A61K38/00 , A61K38/04 , A61K38/05 , A61K38/06 , A61K38/55 , A61P1/00 , A61P7/02 , A61P11/02 , A61P11/06 , A61P17/00 , A61P19/02 , A61P25/28 , A61P29/00 , A61P43/00 , C07C237/12 , C07C257/00 , C07C257/16 , C07C257/18 , C07C271/64 , C07D205/00 , C07D205/04 , C07D207/00 , C07D207/09 , C07D211/00 , C07D211/16 , C07D211/26 , C07D211/60 , C07D239/00 , C07D239/14 , C07K1/10 , C07K2/00 , C07K5/00 , C07K5/02 , C07K5/04 , C07K5/06 , C07K5/062 , C07K5/065 , C07K5/078 , C07K5/08 , C12N9/99
摘要： PROBLEM TO BE SOLVED: To provide the subject compound as starting material in synthesizing a serine protease inhibitor, and to provide the corresponding new structural fragment in the above inhibitor. SOLUTION: This compound itself shown by the formula or the corresponding compound having an amidino group with the nitrogen atom(s) therein mono- or diprotected or a salt thereof is to be used as starting material in synthesizing a serine protease inhibitor as a peptide, in particular a thrombin inhibitor or kininogenase inhibitor as a peptide. The other objective corresponding structural fragment of the other formula as the structural element of a pharmaceutically active compound, in particular a peptide compound as one of the above- mentioned inhibitors is provided.

9. 发明专利

JP3222846B2 失效
公开(公告)号：JP3222846B2
公开(公告)日：2001-10-29
申请号：JP31236698
申请日：1998-11-02
IPC分类号： C07D295/18 , A61K8/00 , A61K8/40 , A61K8/46 , A61K31/00 , A61K31/17 , A61K31/27 , A61K31/275 , A61K31/445 , A61K31/4453 , A61K31/4465 , A61P17/00 , A61P17/14 , A61Q5/00 , A61Q7/00 , C07C269/04 , C07C271/64 , C07C273/18 , C07C275/50 , C07D295/215 , A61K7/06

10. 发明专利

JP2001514634A 失效
公开(公告)号：JP2001514634A
公开(公告)日：2001-09-11
申请号：JP53912398
申请日：1998-02-16
IPC分类号： C07D263/42 , A61K31/165 , A61K31/192 , A61K31/216 , A61P9/10 , A61P25/08 , A61P25/14 , A61P25/16 , A61P25/28 , A61P43/00 , C07C51/09 , C07C62/28 , C07C62/38 , C07C67/14 , C07C69/743 , C07C69/757 , C07C227/18 , C07C229/48 , C07C233/60 , C07C233/81 , C07C235/82 , C07C237/24 , C07C259/08 , C07C271/24 , C07C271/64 , C07C311/51 , C07D263/52

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