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1. 发明专利

JP2014062793A Device for nucleic acid detection 审中-公开
标题翻译：核酸检测装置
公开(公告)号：JP2014062793A
公开(公告)日：2014-04-10
申请号：JP2012207523
申请日：2012-09-20
申请人： Toshiba Corp , 株式会社東芝
发明人： YAMAMOTO KEIICHI , HIROZAWA DAIJI , KUWABARA TETSUYA , OKADA JUN , YUMOTO MASAYUKI
IPC分类号： G01N35/08 , G01N37/00
摘要： PROBLEM TO BE SOLVED: To provide a device for nucleic acid detection with improved reliability.SOLUTION: A device for nucleic acid detection includes: a substrate; a reagent part for storing a specimen sample and a reagent; a reaction part which is prepared on the substrate and performs amplification detection of nucleic acid on the specimen sample; a discharge part which is provided between the reagent part and the reaction part and by which a used reagent is discharged; a first channel for connecting the reagent part and the reaction part; and a second channel for connecting the reaction part and the discharge part.
摘要翻译：要解决的问题：提供具有提高的可靠性的用于核酸检测的装置。解决方案：用于核酸检测的装置包括：底物; 用于存储样本样品和试剂的试剂部分; 反应部分，其在基板上制备，并对样品上的核酸进行扩增检测; 排出部，其设置在所述试剂部和所述反应部之间，并且使用所述试剂排出; 用于连接试剂部分和反应部分的第一通道; 以及用于连接反应部分和排出部分的第二通道。

2. 发明专利

JP2014060924A Nucleic acid detection device and nucleic acid detection apparatus 有权
标题翻译：核酸检测装置和核酸检测装置
公开(公告)号：JP2014060924A
公开(公告)日：2014-04-10
申请号：JP2012206216
申请日：2012-09-19
申请人： Toshiba Corp , 株式会社東芝
发明人： OKADA JUN , HIROZAWA DAIJI , TAKASE MADOKA , KUWABARA TETSUYA , YAMAMOTO KEIICHI
IPC分类号： C12M1/00
摘要： PROBLEM TO BE SOLVED: To provide a nucleic acid detection device which reduces an in-plane temperature distribution in a DNA chip, and a nucleic acid detection apparatus.SOLUTION: A nucleic acid detection device comprises a first component, and a second component. The first component comprises: a substrate; a plurality of sensors which are disposed on the surface of the substrate to detect a nucleic acid; a first electrode pad which is disposed on the surface of the substrate to take out a detection signal detected by the sensors; and a second electrode pad which is disposed at a different position from the first electrode pad on the surface of the substrate to take out the detection signal detected by the sensor. The second component comprises a groove part which is formed on the surface facing the surface of the substrate to face the sensors and to be a passage for feeding a reagent onto the sensors. The first electrode pad and the second electrode pad are arranged to sandwich a passage region defined by the groove part on the surface of the substrate.
摘要翻译：要解决的问题：提供降低DNA芯片内的面内温度分布的核酸检测装置和核酸检测装置。解决方案：核酸检测装置包括第一成分和第二成分。第一组分包括：基材; 设置在所述基板的表面上以检测核酸的多个传感器; 第一电极焊盘，其设置在所述衬底的表面上，以取出由所述传感器检测到的检测信号; 以及第二电极焊盘，其设置在与所述衬底的表面上的所述第一电极焊盘不同的位置，以取出由所述传感器检测的检测信号。第二部件包括形成在面向基板的表面的表面上以面对传感器的凹槽部分，并且是用于将试剂馈送到传感器上的通道。第一电极焊盘和第二电极焊盘被布置成将由槽部限定的通道区域夹在基板的表面上。

3. 发明专利

JP2013198419A Nucleic acid detection device 有权
标题翻译：核酸检测装置
公开(公告)号：JP2013198419A
公开(公告)日：2013-10-03
申请号：JP2012067946
申请日：2012-03-23
申请人： Toshiba Corp , 株式会社東芝
发明人： OKADA JUN , NIKAIDO MASARU , MOTOMA NOBUHIRO , HIROZAWA DAIJI , YAMAMOTO KEIICHI , KUWABARA TETSUYA , TAKASE MADOKA
IPC分类号： C12M1/34 , C12N15/09 , G01N27/327
摘要： PROBLEM TO BE SOLVED: To provide a nucleic acid detection device for reducing the inhibition of an amplification reaction of a nucleic acid.SOLUTION: This nucleic acid detection device includes a substrate, a sensor part, wiring, and a protection part. The sensor part is for nucleic acid detection, formed on the substrate. The wiring is formed on the substrate and connected with the sensor. The protection membrane is formed on the substrate. The nucleic acid detection device performs detection of a nucleic acid amplification product by the sensor part after a nucleic acid amplification reaction is performed in a chamber for the sensor part and a nucleic acid sample to react. The protection membrane is provided with one or more openings to expose a lower part including a part of the substrate in a liquid contact region of the nucleic acid sample on the substrate.
摘要翻译：要解决的问题：提供一种用于降低核酸扩增反应抑制的核酸检测装置。解决方案：该核酸检测装置包括基板，传感器部件，布线和保护部件。传感器部分用于在基底上形成的核酸检测。布线形成在基板上并与传感器连接。保护膜形成在基板上。核酸检测装置在用于传感器部分的室和核酸样品进行核酸扩增反应之后，通过传感器部分进行核酸扩增产物的检测。保护膜设置有一个或多个开口，以在衬底上的核酸样品的液体接触区域中露出包括衬底的一部分的下部。

4. 发明专利

JP2013192521A Nucleic acid detection cassette and nucleic acid detecting device 有权
标题翻译：核酸检测CASSETTE和核酸检测设备
公开(公告)号：JP2013192521A
公开(公告)日：2013-09-30
申请号：JP2012064457
申请日：2012-03-21
申请人： Toshiba Corp , 株式会社東芝
发明人： HIROZAWA DAIJI , OKADA JUN , KUWABARA TETSUYA , YAMAMOTO KEIICHI , TAKASE MADOKA
IPC分类号： C12M1/00 , G01N37/00
摘要： PROBLEM TO BE SOLVED: To provide a compact sealed type nucleic acid detection cassette and a nucleic acid detecting device, which are suitably used to automatically perform processing from amplification to detection of a target nucleic acid with consistency.SOLUTION: A nucleic acid detection cassette includes: a flow path packing, a first plate, and a second plate. The flow path packing includes a nucleic acid detection channel; a first syringe for storing a nucleic acid sample; a second syringe for storing a medicinal solution used for nucleic acid detection; a third syringe for storing a liquid flowing out of the nucleic acid detection channel; a first flow path connecting the first syringe and second syringe to the nucleic acid detection channel; and a second flow path connecting the nucleic acid detection channel to the third syringe, which are integrally made from a soft material. The first plate and the second plate are made from a hard material, and seal the flow path packing.
摘要翻译：要解决的问题：提供一种适合用于自动执行从扩增到检测具有一致性的靶核酸的处理的紧凑型密封型核酸检测盒和核酸检测装置。解决方案：核酸检测盒包括：流路填料，第一板和第二板。流路包装包括核酸检测通道; 用于储存核酸样品的第一注射器; 用于存储用于核酸检测的药液的第二注射器; 用于储存从核酸检测通道流出的液体的第三注射器; 将第一注射器和第二注射器连接到核酸检测通道的第一流路; 以及将核酸检测通道与第三注射器连接的第二流路，其由软质材料一体制成。第一板和第二板由硬质材料制成，并密封流路填料。

5. 发明专利

JP2006136621A Method for decomposition treatment of organic compound and apparatus thereof 审中-公开
标题翻译：有机化合物的分解处理方法及其装置
公开(公告)号：JP2006136621A
公开(公告)日：2006-06-01
申请号：JP2004330641
申请日：2004-11-15
申请人： Toshiba Corp , Toshiba Plant Systems & Services Corp , 東芝プラントシステム株式会社 , 株式会社東芝
发明人： SATO NOZOMI , SHOJI YUICHI , ISHII SHINICHI , YAMAMOTO KEIICHI , OMORI ICHIRO , HARA HIDEKI
IPC分类号： A62D3/32 , A62D101/22 , A62D101/26 , A62D101/28 , B01J19/24 , C07D319/24
摘要： PROBLEM TO BE SOLVED: To provide a method for decomposition treatment of organic compound and an apparatus thereof, by which a decomposition ratio is improved by decomposing organic compound in a reaction vessel for decomposing the organic compound in molten salt.
SOLUTION: The method for decomposition treatment of the organic compound comprises: a decomposition process for decomposing the organic compound by supplying the organic compound into the molten salt in the reaction vessel 2; a mist generation process for generating the mist of the molten salt by making gas containing undecomposed gas which is not decomposed in the decomposition process blow into the molten salt in the reaction vessel 2; a mist attachment process for suspending the mist of the molten salt in a gas phase part 2a existing in the reaction vessel 2 and applying the mist to a baffle plate 9 provided at the gas phase part 2a; and a decomposition process by the mist for decomposing the organic compound by bringing the organic compound into contact with the mist of the molten salt.
COPYRIGHT: (C)2006,JPO&NCIPI
摘要翻译：待解决的问题：提供一种有机化合物的分解处理方法及其装置，通过在用于分解熔融盐中的有机化合物的反应容器中分解有机化合物来提高分解比。解决方案：有机化合物的分解处理方法包括：通过将有机化合物供应到反应容器2中的熔融盐中来分解有机化合物的分解方法; 通过使在分解工序中不分解的未分解气体的气体在反应容器2内吹入熔盐而产生熔融盐雾的雾产生工序; 用于将熔盐的雾悬浮在存在于反应容器2中的气相部分2a中并将雾施加到设置在气相部分2a的挡板9上的雾附着过程; 以及通过使有机化合物与熔融盐的雾接触而通过雾分解有机化合物的分解过程。版权所有（C）2006，JPO＆NCIPI

6. 发明专利

JP2005198709A Method and apparatus for decomposition processing of organic compound 审中-公开
标题翻译：有机化合物分解处理方法及装置
公开(公告)号：JP2005198709A
公开(公告)日：2005-07-28
申请号：JP2004005755
申请日：2004-01-13
申请人： Toshiba Corp , Toshiba Plant Systems & Services Corp , 東芝プラントシステム株式会社 , 株式会社東芝
发明人： HODOZUKA MASATOSHI , SHOJI YUICHI , SATO NOZOMI , YAMAMOTO KEIICHI , OMORI ICHIRO , HARA HIDEKI
IPC分类号： A62D3/32 , A62D101/22 , A62D101/26 , A62D101/28 , C07B35/06 , C07B37/06 , A62D3/00
摘要： PROBLEM TO BE SOLVED: To provide a technique capable of decomposing organic compounds to harmless compounds without discharging harmful compounds into environment in the process and stably supplying an undecomposed gas in such conditions where a pressure is varied by the generation and bursting of air bubbles generated by the blow-in of a gas to molten salt and the decomposition of organic components. SOLUTION: A method for decomposition processing of the organic compounds includes: a decomposing process of feeding the organic compounds into the molten salt and decomposing the organic compounds; and a feeding process of feeding the gas undecomposed in the decomposing process to the molten salt again. A gas transfer device for transferring the undecomposed gas and/or a decomposed gas to be used in the feeding process is controlled to maintain the pressure of the vapor phase part in a reaction vessel where the molten salt and the organic compounds react or the molar quantity of a processing object gas constant. COPYRIGHT: (C)2005,JPO&NCIPI
摘要翻译：要解决的问题：提供一种能够将有机化合物分解成无害化合物而不在该过程中将有害化合物排放到环境中并在稳定地供应未分解气体的条件下，其中压力由于空气的产生和破裂而变化通过气体熔化成熔融盐而产生的气泡和有机组分的分解。解决方案：有机化合物的分解处理方法包括：将有机化合物进料到熔融盐中并分解有机化合物的分解过程; 以及将在分解过程中未分解的气体再次进料到熔融盐的进料方法。控制用于输送未分解气体和/或用于进料过程中的分解气体的气体转移装置，以保持熔融盐和有机化合物反应的反应容器中气相部分的压力或摩尔量的处理对象气体常数。版权所有（C）2005，JPO＆NCIPI

7. 发明专利

JP2014060925A Nucleic acid detection device and nucleic acid detection apparatus 有权
标题翻译：核酸检测装置和核酸检测装置
公开(公告)号：JP2014060925A
公开(公告)日：2014-04-10
申请号：JP2012206217
申请日：2012-09-19
申请人： Toshiba Corp , 株式会社東芝
发明人： OKADA JUN , HIROZAWA DAIJI , TAKASE MADOKA , KUWABARA TETSUYA , YAMAMOTO KEIICHI
IPC分类号： C12M1/00 , C12N15/09 , G01N33/53
摘要： PROBLEM TO BE SOLVED: To provide a nucleic acid detection device which is highly integrated, and a nucleic acid detection apparatus.SOLUTION: A nucleic acid detection device comprises a first member which includes a substrate and a plurality of sensor parts. The sensor parts are arranged in a plurality of rows along a first direction and in a zigzag pattern on the substrate.
摘要翻译：要解决的问题：提供高度一体化的核酸检测装置和核酸检测装置。解决方案：核酸检测装置包括包括基板和多个传感器部件的第一部件。所述传感器部件沿着所述基板上的第一方向和之字形图案排成多列。

8. 发明专利

JP2006084432A Diagnostic nuclear medicine imaging system and manufacturing control method of radiopharmaceutical used therfor 审中-公开
标题翻译：诊断核医学成像系统及其使用的无线电技术的制造控制方法
公开(公告)号：JP2006084432A
公开(公告)日：2006-03-30
申请号：JP2004272006
申请日：2004-09-17
申请人： Toshiba Corp , 株式会社東芝
发明人： YAMAMOTO KEIICHI , KAWAZU SHIYOUJI , KIMURA HIRONOBU , ABE HIROAKI
IPC分类号： G01T1/161 , G06Q50/22 , G06Q50/24
摘要： PROBLEM TO BE SOLVED: To provide a diagnostic nuclear medicine imaging system and manufacturing control method of radiopharmaceutical used therefor with easy administrative of radiopharmaceutical, prompt and easy confirmation of kinds and amount of nuclides contained in the radiopharmaceutical and enhanced degree of freedom of the system installation. SOLUTION: In the diagnostic nuclear medicine imaging system 10 which is comprised of an accelerator 13 manufacturing radioactive nuclide 12 emitting positron, a medicine synthesizing apparatus 15 manufacturing radiopharmaceutical 14 using this radioactive nuclide 12, and diagnostic test device 16 utilizing positron emission tomography, a recording disclosure means 24 is utilized to record required information, such as kinds and amount of radioactive nuclide contained in the radiopharmaceutical 14 manufactured by the medicine synthesizing apparatus 15, manufacturing date and the like. COPYRIGHT: (C)2006,JPO&NCIPI
摘要翻译：要解决的问题：为了提供用于放射性药物的放射性药物的诊断性核医学成像系统和制造控制方法，容易地管理放射性药物，迅速且容易地确认放射性药物中所含的核素的种类和数量以及增强的自由度系统安装。解决方案：在由制造放射性核素12发射正电子的加速器13构成的诊断性核医学成像系统10中，使用该放射性核素12制造放射性药物14的药物合成装置15以及利用正电子发射断层摄影术的诊断检查装置16 记录公开装置24用于记录由药物合成装置15制造的放射性药剂14中所含的放射性核素的种类和数量等的制造日期等所需的信息。版权所有（C）2006，JPO＆NCIPI

9. 发明专利

JP2005342569A Molten salt tank of waste treatment apparatus 审中-公开
标题翻译：垃圾处理设备的盐罐
公开(公告)号：JP2005342569A
公开(公告)日：2005-12-15
申请号：JP2004162481
申请日：2004-05-31
申请人： Toshiba Corp , 株式会社東芝
发明人： HINO TAKEHISA , KAMEDA TSUNEJI , HODOZUKA MASATOSHI , SHOJI YUICHI , YAMAMOTO KEIICHI
IPC分类号： A62D3/32 , A62D101/22 , A62D101/28 , B01J19/02 , C23C4/08 , A62D3/00
摘要： PROBLEM TO BE SOLVED: To improve the durability of a molten salt tank provided in a waste treatment apparatus and to improve the workability when the inside surface of the molten salt tank is coated.
SOLUTION: This waste treatment apparatus 10 is used for detoxifying CCl
2 F
2 (chlorofluorocarbon 12) by bringing CCl
2 F
2 into contact with a solution A of 100% NaOH in the molten salt tank 12. At least the inside surface of the molten salt tank 12 is covered with a coating film of a thermal-sprayed coating layer 13 to be formed by thermal-spraying corrosion-resistant Ni power. The coating film of the thermal-sprayed coating layer 13 for covering the inside surface of the molten salt tank 12 is formed by thermal-spraying a nickel material.
COPYRIGHT: (C)2006,JPO&NCIPI
摘要翻译：要解决的问题：提高设置在废物处理装置中的熔融盐罐的耐久性，并且当熔融盐罐的内表面被涂覆时，提高加工性。
解决方案：该废物处理装置10用于通过使CCl 2 F 2 （氯氟碳化合物12）对CCl 2 SB > 2 与熔融盐罐12中的100％NaOH溶液A接触。至少熔融盐罐12的内表面被热喷涂层13的涂膜覆盖为通过热喷涂耐蚀Ni电源形成。通过热镀镍材料形成用于覆盖熔融盐槽12的内表面的热喷涂层13的涂膜。版权所有（C）2006，JPO＆NCIPI

10. 发明专利

JP2005334524A System and method for destroying cancer cell 审中-公开
标题翻译：破坏癌细胞的系统和方法
公开(公告)号：JP2005334524A
公开(公告)日：2005-12-08
申请号：JP2004160562
申请日：2004-05-31
申请人： Toshiba Corp , 株式会社東芝
发明人： YAMAMOTO KEIICHI , KAWAZU SHIYOUJI , IGARASHI YASUHARU
IPC分类号： A61N5/10 , B01J35/02
摘要： PROBLEM TO BE SOLVED: To reduce the exposure to radiation by selectively destroying cancer cells in a living body by a cancer cell destroying system without being limited by the kind of cancer or the position of an affected part.
SOLUTION: The cancer cell destroying system for destroying cancer cells in the living body comprises a photocatalyst infusion unit 10 for infusing a photocatalyst into cancer cells, a radioactive formulation infusion unit 20 for infusing a radioactive formulation emitting radiation into the cancer cells. The radioactive formulation is, for example, the one emitting gamma rays, and such a radionuclide is used as is easily taken in cancer cells or in a region where cancer cells are present. The photocatalyst is titanium oxide. The cancer cell destroying system also has a radiation measuring part 9 for confirming the state of attenuation of radiation infused into the living body.
COPYRIGHT: (C)2006,JPO&NCIPI
摘要翻译：要解决的问题：通过选择性地通过癌细胞破坏系统破坏活体中的癌细胞来减少暴露于辐射，而不受癌症的种类或受影响部位的限制。解决方案：用于破坏活体中的癌细胞的癌细胞破坏系统包括用于将光催化剂注入癌细胞的光催化剂输注单元10，用于将放射性制剂放射入癌细胞的放射性制剂输注单元20。放射性制剂是例如发射γ射线，并且使用这样的放射性核素容易摄取在癌细胞中或在存在癌细胞的区域中。光催化剂是氧化钛。癌细胞破坏系统还具有用于确认输入到生物体内的放射线的衰减状态的辐射测定部9。版权所有（C）2006，JPO＆NCIPI

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