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1. 发明专利

JP2020117791A 判定方法及び処理方法审中-公开
公开(公告)号：JP2020117791A
公开(公告)日：2020-08-06
申请号：JP2019011524
申请日：2019-01-25
申请人： TOSHIBA CORP , KIOXIA CORP , UNIV TOHOKU
发明人： UCHIDA KENYA , FUKUI HIROYUKI , UEMATSU IKUO , IWAMOTO TAKEAKI , KWON EUNSANG
IPC分类号： C23C16/44 , H01L21/31
摘要：【課題】副生成物の処理の進行を判定する方法、及び、この判定方法を利用した副生成物の処理方法を提供する。【解決手段】実施形態によると、判定方法が提供される。判定方法は、ケイ素及びハロゲンを含む物質を反応させる、或いは、ケイ素を含む物質とハロゲンを含む物質とを反応させる工程において生じる副生成物の処理の進行を判定する。副生成物の処理は、副生成物に水を含む処理液を接触させて第1固形物を得ることを含む。判定方法は、第1固形物についてのSi−α結合(αはF、Cl、Br、及びIからなる群より選ばれる少なくとも1種である)及びSi−H結合の少なくとも一方の化学分析によるシグナルに基づいて、副生成物の処理の進行を判定することを含む。【選択図】図5

2. 发明专利

JP2009240580A Analytical method and device of biogenic substance, and extraction cartridge 有权
标题翻译：分析方法和生物物质和提取盒的装置
公开(公告)号：JP2009240580A
公开(公告)日：2009-10-22
申请号：JP2008091599
申请日：2008-03-31
申请人： Sysmex Corp , Toshiba Corp , シスメックス株式会社 , 株式会社東芝
发明人： KOJIMA JUNKO , MAEKAWA YASUNORI , TAKASE TOMOHIRO , UEMATSU IKUO , HIRAKAWA MASAAKI , NAWATA ISAO , TONO ICHIRO , KASAI SHINGO
IPC分类号： A61B5/157
CPC分类号： A61B5/14514 , A61B5/14532 , A61B5/1455 , A61B5/150022 , A61B5/150091 , A61B5/150229 , A61B5/150251 , A61B5/150343 , A61B5/150358 , A61B5/150748 , A61B5/150984 , A61B5/15113 , A61B5/15186 , A61B5/1519 , A61B5/157 , A61B5/6824 , A61B5/685 , C12Q1/006
摘要： PROBLEM TO BE SOLVED: To provide analytical method and device of biogenic substance and an extraction cartridge capable of highly precisely analyzing an extract extracted from a subject. SOLUTION: A blood glucose level estimation device (biogenic substance analytical device) 100 includes: an extract medium retention section 53 configured to retain a predetermined amount of extract medium; a reaction section 54 producing a predetermined reaction by glucose; a detection section 40 detecting the glucose from the predetermined reaction generated in the reaction section 54; a liquid storage section 52 storing the glucose by an amount equal to the predetermined amount retained by the extract medium retention section 53; a pump 18 carrying the extract medium stored in the liquid storage section 52 to the extract medium retention section 53 and carrying a part of the extract medium carried to the extract medium retention section 53 and retaining the glucose extracted from the subject, from the extraction medium retention section 53 to the reaction section 54; and a control section 17 analyzing a detection result of the glucose. COPYRIGHT: (C)2010,JPO&INPIT
摘要翻译：要解决的问题：提供能够高精度地分析从受试者提取的提取物的生物源物质和提取盒的分析方法和装置。解决方案：血糖值估计装置（生物来源物质分析装置）100包括：提取介质保持部53，被配置为保持预定量的提取介质; 由葡萄糖产生预定反应的反应部54; 从反应部54中产生的规定的反应检测葡萄糖的检测部40; 储存葡萄糖量等于由提取介质保留部分53保留的预定量的液体存储部分52; 将存储在液体储存部52中的提取介质携带到提取介质保留部53并将被携带的提取介质的一部分携带到提取介质保留部53并保留从被检体提取的葡萄糖从提取介质保持部53到反应部54; 以及分析葡萄糖的检测结果的控制部17。版权所有（C）2010，JPO＆INPIT

3. 发明专利

JP2009150908A Optical waveguide type biochemical sensor chip, its design method, and method of measuring object to be measured 有权
标题翻译：光波导型生物传感器芯片，其设计方法和测量对象的测量方法
公开(公告)号：JP2009150908A
公开(公告)日：2009-07-09
申请号：JP2009087629
申请日：2009-03-31
申请人： Toshiba Corp , 株式会社東芝
发明人： TONO ICHIRO , OMIYA KAYOKO , TAKASE TOMOHIRO , UEMATSU IKUO
IPC分类号： G01N21/27
摘要： PROBLEM TO BE SOLVED: To provide an optical waveguide type biochemical sensor chip capable of widening an allowed incident angle range, while keeping high sensitivity, and inhibiting decay of light intensity in the optical waveguide. SOLUTION: The optical waveguide type biochemical chip includes an optical waveguide layer of polymer resin material, a coupler for making light incident on the optical waveguide layer, a decoupler for making light translated through the optical waveguide layer exit, and a sensing membrane provided on the optical waveguide layer while generating a reaction product which has absorptivity to the light or to the evanescent wave of the light if an analyte is made to interact. The optical waveguide type biochemical sensor chip is characterized by that the decreasing rate R of the output signal after T hours from being interacted with the analyte can be displayed under the specific condition. COPYRIGHT: (C)2009,JPO&INPIT
摘要翻译：要解决的问题：提供一种能够在保持高灵敏度的同时扩大允许的入射角范围并抑制光波导中的光强度的衰减的光波导型生化传感器芯片。解决方案：光波导型生物化学芯片包括聚合物树脂材料的光波导层，用于使入射在光波导层上的光的耦合器，用于使通过光波导层出口折射的光的解耦器，以及感测膜提供在光波导层上，同时产生如果使分析物相互作用，其具有对光或光的ev逝波的吸收性的反应产物。光波导型生化传感器芯片的特征在于，可以在特定条件下显示出与分析物相互作用的T小时后的输出信号的降低率R. 版权所有（C）2009，JPO＆INPIT

4. 发明专利

JP2008122265A Color development reaction detection device and its manufacturing method 审中-公开
标题翻译：颜色发展反应检测装置及其制造方法
公开(公告)号：JP2008122265A
公开(公告)日：2008-05-29
申请号：JP2006307457
申请日：2006-11-14
申请人： Toshiba Corp , 株式会社東芝
发明人： TAKASE TOMOHIRO , NAWATA ISAO , UEMATSU IKUO , HIRAKAWA MASAAKI
IPC分类号： G01N21/78
摘要： PROBLEM TO BE SOLVED: To provide a color development reaction detection device capable of stably measuring the mass of a sensing target even in a case that a temperature change occurs, and to provide its manufacturing method.
SOLUTION: The color development reaction detection device is equipped with a light source 11 coming into contact with a specimen to emit the light guided through the light guide film 14b provided to a biosensor 14 for acquiring the physiological data of the specimen, a first measuring means 11a for measuring the temperature of the light source 11, a second measuring means 15 for detecting the light guided through the light guide film 14b to measure a light detection signal value and a correction means 16b for correcting a reference value when the attenuation of a light detection signal is calculated from the temperature measured by the first measuring means 11a and calculating the attenuation rate of the light detection signal on the basis of the corrected reference value and the light detection signal value measured by the second measuring means 15.
COPYRIGHT: (C)2008,JPO&INPIT
摘要翻译：要解决的问题：提供即使在发生温度变化的情况下也能够稳定地测量感测对象的质量并提供其制造方法的显色反应检测装置。解决方案：显色反应检测装置配备有与试样接触的光源11，以发射通过设置在用于获取试样的生理数据的生物传感器14的导光膜14b所引导的光，用于测量光源11的温度的第一测量装置11a，用于检测通过导光膜14b引导的光以测量光检测信号值的第二测量装置15;以及用于在衰减时校正参考值的校正装置16b 根据由第一测量装置11a测量的温度计算光检测信号，并且基于校正的参考值和由第二测量装置15测量的光检测信号值来计算光检测信号的衰减率。 P>版权所有（C）2008，JPO＆INPIT

5. 发明专利

JP2008022763A Optical glucose sensor chip and method for producing the same 有权
标题翻译：光学葡萄糖传感器芯片及其制造方法
公开(公告)号：JP2008022763A
公开(公告)日：2008-02-07
申请号：JP2006198173
申请日：2006-07-20
申请人： Toshiba Corp , 株式会社東芝
发明人： UEMATSU IKUO , HIRAKAWA MASAAKI , OOMIYA KAYOKO
IPC分类号： C12M1/34 , G01N21/78
CPC分类号： C12Q1/002 , C12Q1/006 , G01N21/552 , G01N21/78
摘要： PROBLEM TO BE SOLVED: To provide an optical glucose sensor chip suppressing or preventing time-lapse deterioration of first and second enzymes in a sensing film.
SOLUTION: The optical glucose sensor chip comprises the following: a base plate; a pair of optical elements formed at the main surface of the base plate, making light incident into the base plate and making the incident light emit out of the base plate; and a glucose sensing film formed at the main surface of the base plate disposed between the optical elements, containing a coloring agent, a first enzyme oxidizing or reducing glucose and a second enzyme generating substance reacting with the generated material of the first enzyme so as to make the coloring agent develop colors, and a nonionic cellulose derivative. The sensing film has a structure that at least one of the first and second enzymes is covered with ionic polymer, where a cushioning agent is taken and the enzymes and the coloring agent are held by the nonionic cellulose derivative.
COPYRIGHT: (C)2008,JPO&INPIT
摘要翻译：要解决的问题：提供抑制或防止感测膜中第一和第二酶的延时劣化的光学葡萄糖传感器芯片。解决方案：光学葡萄糖传感器芯片包括：底板; 形成在所述基板的主表面的一对光学元件，使入射到所述基板中并使所述入射光从所述基板射出的光; 以及葡萄糖感测膜，其形成在设置在所述光学元件之间的所述基板的主表面处，所述葡萄糖感测膜含有着色剂，第一酶氧化还原葡萄糖和与所述第一酶的产生物质反应的第二酶产生物质，以便使着色剂显色，和非离子纤维素衍生物。感测膜具有以下结构：第一和第二酶中的至少一个被离子聚合物覆盖，其中采用缓冲剂，酶和着色剂由非离子纤维素衍生物保持。版权所有（C）2008，JPO＆INPIT

6. 发明专利

JP2006267052A Inspection apparatus for measuring immune reaction 审中-公开
标题翻译：用于测量免疫反应的检查装置
公开(公告)号：JP2006267052A
公开(公告)日：2006-10-05
申请号：JP2005089453
申请日：2005-03-25
申请人： Toshiba Corp , 株式会社東芝
发明人： UCHIYAMA KENICHI , OOMIYA KAYOKO , KASAI SHINGO , UEMATSU IKUO , TAKASE TOMOHIRO , NAWATA ISAO , TONO ICHIRO
IPC分类号： G01N21/64 , G01N21/78
摘要： PROBLEM TO BE SOLVED: To provide an inspection apparatus for measuring an immune reaction that can excite a labeled coloring matter, after an antigen/antibody reaction in solution in the entire cell, propagates fluorescence radiated by excitation onto a transparent plate for radiating to the outside, and can essentially detect the intensity of only the fluorescence by a light-receiving element.
SOLUTION: The inspection apparatus for measuring an immune reaction comprises the transparent plate; a sensor chip, having a cell that is arranged at least at one location on the surface of the transparent plate and stores the solution of reagents and specimens, a grating that is formed on the transparent plate at the bottom of the cell and allows the fluorescence to enter the transparent plate, and an optical element that is formed on the surface of the transparent plate, separated from the cell and radiates fluorescence propagated to the transparent plate by the grating to the outside; an excitation light irradiation means for irradiating the cell of the sensor chip, with the excitation light along the depth direction of the cell; and a light-receiving means for receiving the fluorescence radiated from the optical element of the sensor chip.
COPYRIGHT: (C)2007,JPO&INPIT
摘要翻译：要解决的问题：提供一种用于测量可激发标记色素的免疫反应的检查装置，在整个细胞溶液中的抗原/抗体反应之后，将通过激发辐射的荧光传播到用于辐射的透明板上并且可以基本上通过光接收元件检测仅荧光的强度。解决方案：用于测量免疫反应的检查装置包括透明板; 传感器芯片，具有布置在透明板的表面上的至少一个位置处并存储试剂和试样溶液的电池，形成在电池底部的透明板上的光栅，并允许荧光进入透明板，以及形成在透明板的表面上的与光电元件分离的光学元件，并将通过光栅传播到透明板的荧光发射到外部; 激发光照射装置，用于沿着电池的深度方向照射传感器芯片的电池; 以及用于接收从传感器芯片的光学元件辐射的荧光的光接收装置。版权所有（C）2007，JPO＆INPIT

7. 发明专利

JP2004357721A Optical waveguide type invasion device, invasion induction device and optical waveguide type invasion system 审中-公开
公开(公告)号：JP2004357721A
公开(公告)日：2004-12-24
申请号：JP2003145295
申请日：2003-05-22
申请人： Toshiba Corp , 株式会社東芝
发明人： UCHIYAMA KENICHI , UEMATSU IKUO , OOMIYA KAYOKO , TONO ICHIRO , ETO HIDEO , KISHIMOTO ISAO , OKADA NAOTADA , HIRATA MASAMI , KASHIMA NORIYASU
IPC分类号： G01N21/27 , A61B5/00 , G02B6/122
摘要： PROBLEM TO BE SOLVED: To provide an optical waveguide type invasion device which analyzes a specified substance in body fluid without damaging a living body and without being limited by dissolved oxygen in the body fluid. SOLUTION: The optical waveguide type invasion device comprises: a sensor part 18 provided with a gel layer 12, a negative electrode plate 17 in contact with the gel layer 12 and an optical waveguide plate 15; and a circuit part 20 provided with a light emitting circuit 21 for making light be incident on the optical waveguide plate 15, a light receiving circuit 22 for receiving the light emitted from the optical waveguide plate 15, a control circuit 23 connected to the light emitting circuit 21 and the light receiving circuit 22 for generating measured result data corresponding to the change of the light received in the light receiving circuit 22 and an output circuit 25 for outputting the measured result data. COPYRIGHT: (C)2005,JPO&NCIPI

8. 发明专利

JP2015011775A リチウムイオン二次電池审中-公开
标题翻译：锂离子二次电池
公开(公告)号：JP2015011775A
公开(公告)日：2015-01-19
申请号：JP2013134098
申请日：2013-06-26
申请人：株式会社東芝 , Toshiba Corp
发明人： UEMATSU IKUO , HAYAMIZU NAOYA
IPC分类号： H01M10/052 , H01M2/16 , H01M4/13 , H01M4/70 , H01M10/058
CPC分类号： H01M4/78 , H01M2/1673 , H01M10/0525
摘要：【課題】電極をより効率よく使用できるリチウムイオン二次電池を提供する。【解決手段】実施形態のリチウムイオン二次電池は、複数の凹部を表面に有する第1集電体と、前記第1集電体の上に設けられた第1層であって、第1活物質体と、第1バインダと、第1導電体と、を有する前記第1層と、前記複数の凹部の中に前記第1層を介して設けられ、繊維を含むセパレータと、を備える。【選択図】図1
摘要翻译：要解决的问题：提供能够更有效地使用电极的锂离子二次电池。解决方案：锂离子二次电池包括：表面上具有多个凹部的第一集电体; 第一层，其设置在第一集电体上并具有第一活性物质体，第一粘合剂和第一导体; 以及分隔件，其经由第一层设置在多个凹部中并且包含纤维。

9. 发明专利

JP2013068547A Moisture sensor 审中-公开
标题翻译：水分传感器
公开(公告)号：JP2013068547A
公开(公告)日：2013-04-18
申请号：JP2011207961
申请日：2011-09-22
申请人： Toshiba Corp , 株式会社東芝
发明人： OGURA YO , HAYAMIZU NAOYA , UEMATSU IKUO , SATO KATSUHIRO
IPC分类号： G01N5/02
摘要： PROBLEM TO BE SOLVED: To provide a moisture sensor including a hydrophilic layer having good adhesion to a piezoelectric transducer, and a container including the sensor.SOLUTION: A moisture sensor according to an embodiment has a piezoelectric transducer 1, a pair of electrodes coupled to the piezoelectric transducer 1, a silicon atom bonded to the piezoelectric transducer 1 by covalent bond, and a hydrophilic layer 2 including a hydrophilic part bonded to the silicon atom.

10. 发明专利

JP2011202997A Optical sensor 有权
标题翻译：光传感器
公开(公告)号：JP2011202997A
公开(公告)日：2011-10-13
申请号：JP2010068426
申请日：2010-03-24
申请人： Toshiba Corp , 株式会社東芝
发明人： UEMATSU IKUO , KASAI SHINGO , TONO ICHIRO , NAWATA ISAO
IPC分类号： G01N21/27
CPC分类号： G01N21/7703 , G01N21/78 , G01N2021/7776 , G01N2021/7786
摘要： PROBLEM TO BE SOLVED: To provide an optical sensor capable of avoiding the influence of a precipitate in a specimen.SOLUTION: The optical sensor 1 includes: an optical waveguide part 12; and a specimen area 20 provided adjacent to the optical waveguide part 12 and configured to hold a specimen, wherein a precipitation surface 21 on which a precipitate 27a of the specimen 27 precipitates is disposed at a position different from a position of a sensing surface 23 on the side of the optical waveguide part 12 where an optical change occurs.
摘要翻译：要解决的问题：提供能够避免样品中沉淀物的影响的光学传感器。解决方案：光学传感器1包括：光波导部分12; 以及与光波导部12相邻并配置为保持试样的试样区域20，其中，试样27的析出物27a析出的析出面21配置在与感测面23的位置不同的位置发生光学变化的光波导部分12的一侧。

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