专利快速检索-快速检索全球专利，免费商用专利数据库-IPRDB

1. 发明专利

JP2011179865A Immunoassay method of hepatitis c virus and reagent kit for the same 有权
标题翻译： HEPATITIS C病毒和试剂盒的免疫测定方法
公开(公告)号：JP2011179865A
公开(公告)日：2011-09-15
申请号：JP2010042217
申请日：2010-02-26
申请人： Sysmex Corp , シスメックス株式会社
发明人： TAKAMA TAKUYA , YAMAKAKIUCHI TAKAHIRO , TAKEDA KAZUHIKO
IPC分类号： G01N33/576 , C07K14/18 , G01N33/543 , G01N33/553 , G01N33/577
摘要： PROBLEM TO BE SOLVED: To provide an immune complex transfer enzyme immunoassay method, capable of detecting HCV at a high sensitivity, and to provide a reagent kit employed for the same.
SOLUTION: The immunoassay method for hepatitis C virus (HCV) includes a step of forming a complex body containing a labeled antibody binding to HCV core protein, a primary antibody binding to HCV core protein and HCV core protein on a first solid phase, a step of releasing the complex body formed on the first solid phase and transferring to a second solid phase that is different from the first solid phase, and a step of measuring the label of the complex transferred to the second phase, wherein each of the labeled antibody and the first antibody binds to the different sites of HCV core protein, and the binding sites do not include the 49th amino acid of HCV core protein shown in the sequence No.2.
COPYRIGHT: (C)2011,JPO&INPIT
摘要翻译：要解决的问题：提供能够以高灵敏度检测HCV的免疫复合物转移酶免疫测定法，并提供用于该HCV的试剂盒。解决方案：丙型肝炎病毒（HCV）的免疫测定方法包括形成复合体的步骤，其包含与HCV核心蛋白结合的标记抗体，在第一固相上与HCV核心蛋白和HCV核心蛋白结合的一级抗体释放在第一固相上形成的复合体并转移到与第一固相不同的第二固相的步骤，以及测量转移到第二相的络合物的标记的步骤，其中每个标记抗体，第一抗体结合HCV核心蛋白的不同部位，结合位点不包括序列号2所示的HCV核心蛋白的第49位氨基酸。版权所有（C）2011，JPO＆INPIT

2. 发明专利

JP2011112631A Method for pretreating sample for detection of hepatitis c virus core protein and reagent kit for pretreatment 有权
标题翻译：用于检测乙型肝炎病毒核蛋白和试剂盒预处理样品的方法
公开(公告)号：JP2011112631A
公开(公告)日：2011-06-09
申请号：JP2009272339
申请日：2009-11-30
申请人： Sysmex Corp , シスメックス株式会社
发明人： YAMAKAKIUCHI TAKAHIRO , TAKEDA KAZUHIKO
IPC分类号： G01N33/543 , G01N33/53 , G01N33/576
摘要： PROBLEM TO BE SOLVED: To provide a method for pretreating samples for detection of HCV core protein capable of inhibiting agglutination of particles, and to provide a reagent kit for pretreatment of samples for detecting HCV core protein used for the method. SOLUTION: In HCV core protein detection by an immunoassay using particles, both are provided with a method for pretreating samples for detection of HCV core protein, such that by treating a sample suspected of containing hepatitis C virus with an alkaline material-containing reagent and by one of reagents containing a reducing agent, when being neutralized with an acid-material containing reagent and a reagent kit for pretreatment of samples for detecting HCV core protein used for the method. COPYRIGHT: (C)2011,JPO&INPIT
摘要翻译：待解决的问题：提供一种预处理用于检测能够抑制颗粒凝集的HCV核心蛋白的样品的方法，并提供用于检测用于该方法的HCV核心蛋白的样品的预处理的试剂盒。解决方案：在通过使用颗粒的免疫测定的HCV核心蛋白检测中，两者都具有用于预处理样品以检测HCV核心蛋白的方法，使得通过用含碱性材料处理疑似含有丙型肝炎病毒的样品试剂和含有还原剂的试剂中的一种，用含酸物质试剂中和的试剂和用于检测用于本方法的HCV核心蛋白的样品的预处理试剂盒。版权所有（C）2011，JPO＆INPIT

3. 发明专利

JP2011137747A Method for determining existence of hepatitis c virus in sample, and reagent kit for determining existence of hepatitis c virus 有权
标题翻译：用于确定样品中HEPATITIS C病毒存在的方法和用于确定丙型肝炎病毒存在的试剂盒
公开(公告)号：JP2011137747A
公开(公告)日：2011-07-14
申请号：JP2009298581
申请日：2009-12-28
申请人： Sysmex Corp , シスメックス株式会社
发明人： YAMAKAKIUCHI TAKAHIRO , TAKEDA KAZUHIKO , TAKAMA TAKUYA
IPC分类号： G01N33/576 , G01N33/543
摘要： PROBLEM TO BE SOLVED: To provide a method for determining an existence of a hepatitis C virus in a sample more accurately without causing an agglutination of particles in detecting HCV core protein by an immune complex metastasis measurement method using the particles, and to provide a reagent kit for determining the existence of the hepatitis C virus. SOLUTION: The present invention provides, when the sample suspected of containing the hepatitis C virus is treated with a reagent containing an alkaline substance and neutralized with a reagent containing an acid substance in detecting the HCV core protein by the immune complex metastasis measurement method using the particles, the method for determining the existence of the hepatitis C virus in the sample, wherein either one of the reagents contains a reducing agent; and the reagent kit for determining the existence of the hepatitis C virus. COPYRIGHT: (C)2011,JPO&INPIT
摘要翻译：待解决的问题：提供一种用于通过使用该颗粒的免疫复合物转移测量方法更准确地确定样品中丙型肝炎病毒存在的方法而不引起颗粒凝集检测HCV核心蛋白的方法，提供用于确定丙型肝炎病毒存在的试剂盒。解决方案：本发明提供了当怀疑含有丙型肝炎病毒的样品用含有碱性物质的试剂处理并用含有酸物质的试剂在通过免疫复合物转移测量检测HCV核心蛋白质中中和时使用该颗粒的方法，用于确定样品中丙型肝炎病毒存在的方法，其中任一种试剂含有还原剂; 和用于测定丙型肝炎病毒存在的试剂盒。版权所有（C）2011，JPO＆INPIT

你已经成功收藏专利！

检索式保存成功!

IPRDB

热门服务

关于我们

友情链接

联系方式