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    • 2. 发明专利
    • Hair tonic
    • 头发TONIC
    • JPS6118711A
    • 1986-01-27
    • JP13941484
    • 1984-07-05
    • Pola Chem Ind Inc
    • MOTOYOSHI KATSUHIROKANBE NAOYUKI
    • A61K8/00A61K8/40A61K8/49A61K8/63A61Q5/00A61Q7/00
    • A61Q7/00A61K8/63
    • PURPOSE:To obtain a harmless hair tonic free from side effects, having excellent hair tonic effect and effective to suppress the development of the sebaceous gland and promote the growth of folliculus pili, by compounding one or more cyproterone esters such as cyproterone acetate. CONSTITUTION:The objective hair tonic contains one or more cyporterone esters of formula (R is 2-8C acyl) (e.g. cyproterone isopropionate). The effect of the hair tonic can be further improved by adding a dermatic peripheral vessel dilator such as capuronium chloride, benzyl nicotinate, vitamin E acetate, vitamin E linolate, vitamin E nicotinate, etc. to the cyproterone ester. The hair tonic is effective to most of the patients of male apopecia, and exhibits excellent effect for the prevention of dandrull, falling hair, etc. and the improvement of the luster of the hair, etc.
    • 目的:通过配合一种或多种醋酸环丙孕酮酯,如醋酸环丙孕酮,可以获得无副作用的无害滋润滋润效果,有效抑制皮脂腺发育,促进毛囊生长。 构成:目的头发补品含有一种或多种式(R为2-8C酰基)(例如丙酸环丙孕酮)的顺式酯。 通过向氯化丙酸酯加入诸如氯化铈,外用烟酸苄酯,维生素E乙酸酯,维生素E亚麻酸酯,维生素E烟酸酯等的皮肤外周血管扩张剂,能够进一步提高毛发滋养效果。 头发补品对大多数男性脱落脱落的患者有效,对防止头皮屑,头发脱落等,以及头发光泽的改善等表现出极好的效果。
    • 3. 发明专利
    • Hair tonic
    • 头发TONIC
    • JPS6118710A
    • 1986-01-27
    • JP13941384
    • 1984-07-05
    • Pola Chem Ind Inc
    • MOTOYOSHI KATSUHIROSAITOU EIHACHIKANBE NAOYUKI
    • A61K8/00A61K8/40A61K8/49A61K8/63A61Q5/00A61Q7/00
    • A61K8/63A61Q7/00
    • PURPOSE:To provide a hair tonic containing one or more gestonorone esters such as gestonorone acetate, having high safety and exhibiting excellent hair tonic effect. CONSTITUTION:The objective hair-tonic contains one or more gestonorone esters of formula (R is 2-12C acyl) (e.g. gestonorone isopropionate). Gestonorone is effective to suppress the development of the sebaceous gland, activate the adenyl cyclase existing in the folliculus pili and radix pili, and promote the growth of the folliculus pili. It is harmless to human body and exhibits no side effects. It is preferable to compound the hair tonic with a peripheral dermatic vessel dilator such as capuronium chloride, benzyl nicotinate, vitamin E acetate, vitamin E linolate, vitamin E nicotinate, etc.
    • 目的:提供含有一种或多种孕激素酯如醋酸孕酮的头发补品,具有高安全性和显示出优异的滋养效果。 构成:目的发质含有一种或多种式(R为2-12C酰基)的孕酮酯(例如异丙酸孕酮)。 Gestonorone有效地抑制皮脂腺的发育,激活存在于毛囊和小檗碱中的腺苷酸环化酶,并促进卵泡的生长。 对人体无害,无副作用。 优选将头发补品与周围的皮肤血管扩张器如氯化铈,烟酸苄酯,维生素E乙酸酯,维生素E亚麻酸酯,维生素E烟酸酯等混合。
    • 4. 发明专利
    • SKIN CLASSIFYING METHOD CONSIDERING INFLUENCE OF ULTRAVIOLET RAYS
    • JPH11146866A
    • 1999-06-02
    • JP33352797
    • 1997-11-18
    • POLA CHEM IND INC
    • MOTOYOSHI KATSUHIROOTA YUTAKA
    • A61B5/00A61K8/00A61Q17/04A61K7/42
    • PROBLEM TO BE SOLVED: To realize the classification of a skin adapted to the receiving degree of the influence of ultraviolet rays especially ultraviolet rays A by setting the instant blackening amount of a minimum continuous type of the skin to be an index. SOLUTION: The instant blackening amount of the minimum continuous type of the skin set to be an index can be measured according to reference fixed by Japan cosmetic industry, USA cosmetic industry, etc. For example, through the use of an artificial ultraviolet irradiator, etc., light beams based on long wavelength ultraviolet rays are taken out by a filter for the ultraviolet rays A and this is shaken from a low dose to a high dose to irradiate to judge 2 to four hours after irradiation when blackening appears. As there are cases when the degree of blackening is different depending on a judging time, judging is desirably executed a fixed time after irradiation. From this vie point, reaction is desirably judged at the point of a time when reaction is stabilized three hours after irradiation. As the irradiating place, a part where blackening is not generated by ultraviolet rays such as the inner part of an upper arm, a back part is desirably used.
    • 5. 发明专利
    • JPH05248945A
    • 1993-09-28
    • JP5187692
    • 1992-03-10
    • POLA CHEM IND INC
    • KONDO CHIHOMOTOYOSHI KATSUHIRO
    • A61B10/00G01J1/02G01N21/33
    • PURPOSE:To evaluate ultraviolet ray transmission preventive effect of a specimen such as an anti-suntan cream without use of any vital organism by applying the specimen to the surface of an animal skin exfoliated film having ultraviolet transmissivity, irradiating it with an artificial light beam from one side, and measuring the dosage of ultraviolet rays transmitted. CONSTITUTION:A specimen 2 is applied to the surface of a hairless molmot skin 1, which is adhere4 to a rectangular holder 3 having a square aperture, and the holder 3 is held vertically by a stand. The irradiation part 41 of a solar simulator 40 is attached to the specimen side of the skin 1 while the light-receiving part 51 of an ultraviolet ray intensity meter 50 is attached to the other side, and the intensity E of the ultraviolet ray penetrating the specimen 2 and skin 1 is measured. Alike the intensity E0 of the ultraviolet rays is measured by using the skin 1 which is free from application of specimen 2, and E/E0 is used as the ultraviolet ray transmission prevention value. Accordingly the ultraviolet ray transmission preventive effect can quickly be evaluated without use of any vital organism.
    • 6. 发明专利
    • JPH05248944A
    • 1993-09-28
    • JP5187592
    • 1992-03-10
    • POLA CHEM IND INC
    • KONDO CHIHOMOTOYOSHI KATSUHIRO
    • A61B10/00G01J1/02G01N21/33
    • PURPOSE:To evaluate ultraviolet ray transmission preventive effect of a specimen such as an anti-suntan cream without use of any vital organism by applying the specimen to the surface of an artificial skin film having ultraviolet transmissivity, irradiating it with an artificial light beam from one side, and measuring the dosage of ultraviolet rays transmitted. CONSTITUTION:A specimen 2 is applied to one side of an artificial skin film 1, which is adhered to a rectangular holder 3 having a square aperture, and the holder 3 is held vertically by a stand. The irradiation part 41 of a solar simulator 40 is attached to the specimen side of the film 1 while the light- receiving part 51 of an ultraviolet ray intensity meter 50 is attached to the other side, and the intensity E of the ultraviolet ray penetrating the specimen 2 and film 1 is measured. Alike the intensity E0 of the ultraviolet rays is measured by using the film 1 which is free from application of specimen 2, and E/E0 is used as the ultraviolet ray transmission prevention value. Accordingly the ultraviolet ray transmission preventive effect can quickly be evaluated without use of any vital organism.
    • 10. 发明专利
    • Hair tonic
    • 头发TONIC
    • JPS6168408A
    • 1986-04-08
    • JP19080084
    • 1984-09-12
    • Pola Chem Ind Inc
    • MOTOYOSHI KATSUHIROMAEDA TETSUOISO TOSHIAKIHIROSE TAKUISHIDA TATSUYA
    • A61K8/00A61K8/40A61K8/49A61K8/97A61Q5/00A61Q7/00
    • A61Q5/006A61K8/97A61Q7/00
    • PURPOSE:A hair tonic that contains an extract obtained from Prunus africana barks and, preferably a dermovasodilator such as capronium chloride or benzyl nicotinate, thus having hair tonic effect with high safety. CONSTITUTION:Barks of Prunus africana are dried, extracted with chloroform and the resultant essence is combined with a dermoperipheral vasodilator such as capronium chloride or benzyl nicotinate, vitamin E acetate, vitamin E linolate or vitamin E nicotinate to give the objective hair tonic. This hair tonic has good acceleration effect on hair growth and shows action to inhibit dandruff, hair falling without undesirable side-effect by hormones. The essence of Prunus africana is added by 0.001-5wt% and added as such or in the form of a solution in, e.g., alcohol.
    • 目的:含有从非洲ana属树皮获得的提取物,优选为例如氯化癸酸或烟酸苄酯的皮肤病药,从而具有高安全性的滋养效果的滋补剂。 构成:将黑胡子的树皮干燥,用氯仿萃取,得到的香精与皮肤外周血管扩张剂如氯化癸酸盐,烟酸苄酯,维生素E乙酸盐,维生素E亚麻酸酯或维生素E烟酸酯混合,以提供客观的滋补剂。 这种滋补剂对毛发生长具有良好的加速作用,并且显示出抑制头皮屑的作用,头发下降而没有不希望的激素副作用。 非洲樱桃的精华加入0.001-5重量%,并加入,或以例如酒精的溶液形式加入。