专利快速检索-快速检索全球专利，免费商用专利数据库-IPRDB

1. 发明专利

JP2000290129A PURIFICATION OF PHYSIOLOGICALLY ACTIVE SUBSTANCE INCLUDED IN SOYBEAN 失效
公开(公告)号：JP2000290129A
公开(公告)日：2000-10-17
申请号：JP9442999
申请日：1999-04-01
申请人： POLA CHEM IND INC , CHANSON KESHOHIN KK
发明人： TANAKA MASATO , TSUNEKI AKIRA , FUKUSHIMA MAKOTO , MITANI MAKOTO
IPC分类号： A23G3/34 , A23G3/00 , A23L1/30 , A61K8/00 , A61K8/49 , A61K8/96 , A61K8/97 , A61K31/00 , A61K36/48 , A61P1/00 , A61P1/10 , A61P7/00 , A61P7/10 , A61Q19/10 , A61K7/00 , A61K7/50 , A61K35/78
摘要： PROBLEM TO BE SOLVED: To obtain a physiologically active substance included in soybean in high yield by solvent/solvent extracting the nonvolatile constituent with water and an organic solvent immiscible with water in arbitrary ratio after extracting soybean or its finished articles with a polar solvent. SOLUTION: The physiologically active substance (e.g.; soybean isoflavone and its glucoside or the like) is obtained by extracting soybean and/or its finished articles [e.g.; soybean itself, julienne of dried soybean and its embryo bud, residue of oil and fat squeeze or solvent extract residue (oil cake of soybean) or husk, embryo bud or the like], using 1-10 times of a polar solvent (e.g.; alcohols or the like), leaving alone a few days at room temperature, or a few hours at the temperature close to boiling point of the solvent, under agitation if necessary, after immersing and extracting the nonvolatile ingredient of the above described extract is solvent/solvent extracted with water and the organic solvent (e.g.; normal butanol or the like) immiscible with water in arbitrary ratio, removing organic solvent by vacuum concentration or the like from the obtained organic solvent layer.

2. 发明专利

JP2010180165A Expression promoter for thermogenetic protein 有权
标题翻译：表达蛋白的表达促进剂
公开(公告)号：JP2010180165A
公开(公告)日：2010-08-19
申请号：JP2009025512
申请日：2009-02-06
申请人： Pola Chem Ind Inc , ポーラ化成工業株式会社
发明人： MITANI MAKOTO , FUKUDA TOSHIYUKI , NAKANISHI RUIKO
IPC分类号： A61K31/164 , A23L1/30 , A61K8/42 , A61K8/97 , A61K36/00 , A61K36/75 , A61P1/16 , A61P3/04 , A61P3/10 , A61P9/10 , A61P9/12 , A61P19/02 , A61P43/00 , A61Q19/00
摘要： PROBLEM TO BE SOLVED: To provide an expression promoter for a thermogenetic protein suitable as a component of a body-slimming composition. SOLUTION: The expression promoter for a thermogenetic protein comprises, as an effective ingredient, a component selected from among a compound represented by general formula (1), particularly hydroxy-sanshools, an isomer thereof and/or a pharmacologically acceptable salt thereof. In the formula, R 1 is a 1-6C alkyl group; R 2 is a hydrogen atom or a 1-6C alkyl group; R 3 and R 4 are each independently a 1-6C alkyl group; R 5 is a hydrogen atom or a 1-6C linear or branched alkyl group; l and m are each an integer of 1-5; and n is an integer of 1-3. COPYRIGHT: (C)2010,JPO&INPIT
摘要翻译：要解决的问题：提供适于作为减肥组合物的组分的热致蛋白的表达启动子。解决方案：热致蛋白的表达启动子作为有效成分包含选自通式（1）表示的化合物，特别是羟基三聚体的组分，其异构体和/或其药理学上可接受的盐。在该式中，R SB 1是1-6C烷基; R SB 2是氢原子或1-6C烷基; R SB 3和R SB 4各自独立地为1-6C烷基; R 5是氢原子或1-6C直链或支链烷基; l和m分别为1-5的整数; n为1-3的整数。版权所有（C）2010，JPO＆INPIT

3. 发明专利

JP2007045771A Composition for oral administration 有权
标题翻译：口服药物组合物
公开(公告)号：JP2007045771A
公开(公告)日：2007-02-22
申请号：JP2005232929
申请日：2005-08-11
申请人： Pola Chem Ind Inc , ポーラ化成工業株式会社
发明人： FUKUDA TOSHIYUKI , MITANI MAKOTO
IPC分类号： C07H15/18 , A23L1/30 , A61K31/7034 , A61K31/7048 , A61K36/73 , A61P7/02
摘要： PROBLEM TO BE SOLVED: To provide a technique for suppressing plasminogen activator inhibitor (PAI) by a specific food component.
SOLUTION: The composition for oral administration for the suppression of plasminogen activator inhibitor contains an extract of the flower and/or flower bud of a plant of the genus Prunus, family Rosaeae, preferably Prunus persica and/or Prunus davidiana, as an active component. The extract is produced preferably by extracting the vegetable with hydrated ethanol, removing the extraction solvent, removing n-hexane-soluble component, ethyl acetate-soluble component and n-butyl alcohol-soluble component in the presence of water phase, and removing water from the remaining water phase. The extract preferably contains one or more substances selected from prunacic acid, neoprunacic acid, multinoside A, multiflorine B and their salts as drug active components.
COPYRIGHT: (C)2007,JPO&INPIT
摘要翻译：待解决的问题：提供通过特定食品成分抑制纤溶酶原激活物抑制剂（PAI）的技术。解决方案：用于抑制纤溶酶原激活物抑制剂的口服给药组合物含有植物的花和/或花蕾的提取物，属于植物，如玫瑰花科，优选山梨属植物和/或山梨属（Prunus davidiana），作为活性组分。提取物优选通过用水合乙醇萃取植物，除去萃取溶剂，在水相存在下除去正己烷可溶成分，乙酸乙酯可溶成分和正丁醇可溶成分，剩余的水相。提取物优选含有一种或多种选自prunacic acid，neoprunacic acid，multinoside A，multiflorine B及其盐作为药物活性成分的物质。版权所有（C）2007，JPO＆INPIT

4. 发明专利

JP2003113106A EXPRESSION PROMOTER OF UNCOUPLING PROTEIN AND COMPOSITION CONTAINING THE SAME 审中-公开
公开(公告)号：JP2003113106A
公开(公告)日：2003-04-18
申请号：JP2001304827
申请日：2001-10-01
申请人： POLA CHEM IND INC
发明人： MITANI MAKOTO , FUKUDA TOSHIYUKI , KAMAKURA MASAKI
IPC分类号： A23L1/30 , A61K8/96 , A61K8/97 , A61K36/25 , A61P3/04 , A61K35/78 , A61K7/00
摘要： PROBLEM TO BE SOLVED: To provide a composition for a medicine, a food and a cosmetic for dieting capable of promoting the expression of an uncoupling protein in a brown adipose cell and promoting the inhibition of excessive fat accumulation. SOLUTION: This composition is obtained by formulating an extracted essence which is separated from an old root or a rootlet of a plant of the genus Aralia of the family Araliaceae with a polar solvent and capable of promoting the expression of the uncoupling protein having 32 kDa molecular weight and present in the mitochondrial inner membrane in the brown adipose cell and resultantly inhibiting the excessive fat accumulation with the medicine, food and cosmetic. The resultant composition has excellent antiobese effects.

5. 发明专利

JP2003113096A ACCELERATING AGENT FOR ALBUMIN SYNTHESIS 审中-公开
公开(公告)号：JP2003113096A
公开(公告)日：2003-04-18
申请号：JP2001308591
申请日：2001-10-04
申请人： POLA CHEM IND INC
发明人： KAMAKURA MASAKI , FUKUDA TOSHIYUKI , MITANI MAKOTO
IPC分类号： A23L1/30 , A23L33/10 , A61K35/64 , A61K35/644 , A61P1/16 , A61P7/00 , A61P11/00 , A61P13/12 , A61P17/02 , C07K14/435
摘要： PROBLEM TO BE SOLVED: To provide a medicine or food suitable for recovery/improvement of fatty liver/hepatic adenoma/liver cirrhosis/hemorrhagic shock/traumatic shock/ thermal injury and adult respiratory distress syndrome (ARDS) accompanying hypoalbuminemia/nephrosis. SOLUTION: The invention provides the excellent medicine or food by formulating a sugar protein which is included in royal jerry, having 57 kDa of molecular weight, has recovery/improving function to fatty liver/hepatic adenoma/liver cirrhosis/hemorrhagic shock/traumatic shock/thermal injury and adult respiratory distress syndrome (ARDS) accompanying hypoalbuminemia/nephrosis by promoting alubumin synthesis like a stimulating factor such as Hepatocyte stimulating factor (HSF) or the like.

6. 发明专利

JP2003000163A Royal jelly composition containing hibiscus extract 审中-公开
标题翻译：含有HIBISCUS萃取物的皇家果胶组合物
公开(公告)号：JP2003000163A
公开(公告)日：2003-01-07
申请号：JP2001187555
申请日：2001-06-21
申请人： Pola Chem Ind Inc , ポーラ化成工業株式会社
发明人： KAMAKURA MASAKI , FUKUDA TOSHIYUKI , MITANI MAKOTO , MIYAZAKI HIROTAKA
IPC分类号： A23L21/20 , A61K8/06 , A61K8/96 , A61K8/97 , A61K8/98 , A61K35/64 , A61K36/00 , A61K36/18 , A61P1/14 , A61P3/02 , A61P43/00 , A23L1/076 , A61K7/00 , A61K35/78
摘要： PROBLEM TO BE SOLVED: To provide a method for maintaining the freshness of royal jelly. SOLUTION: Since originating from natural substances, the royal jelly to be formulated with a health food or the like has problems such as the difference of efficacy for each lot and the deterioration of the royal jelly itself. Thereby, it is desired to supply the royal jelly having a stable quality. The formulation of a royal jelly composition with a Hibiscus extract enables the inhibition of the activity of protease in the royal jelly, the stabilization of a protein having a mol.wt. of 57 kilo Dalton as a physiologically active substance, the maintenance of the freshness of the royal jelly, and the stabilization of the quality.
摘要翻译：要解决的问题：提供一种维持蜂王浆新鲜度的方法。解决方案：由天然物质衍生而来，与健康食品等配制的蜂王浆具有各种功效差异和蜂王浆本身劣化等问题。因此，希望提供具有稳定质量的蜂王浆。具有木槿提取物的蜂王浆组合物的配方能够抑制蜂王浆中蛋白酶的活性，稳定具有mol.wt. 的57千道尔顿作为一种生理活性物质，维持蜂王浆的新鲜度和稳定的质量。

7. 发明专利

JP2002338598A INDICATOR SUBSTANCE FOR FRESHNESS OF ROYAL JELLY 失效
公开(公告)号：JP2002338598A
公开(公告)日：2002-11-27
申请号：JP2001145874
申请日：2001-05-16
申请人： POLA CHEM IND INC
发明人： KAMAKURA MASAKI , FUKUDA TOSHIYUKI , MITANI MAKOTO , MIYAZAKI HIROTAKA
IPC分类号： G01N33/02 , A23L21/20 , C07K1/18 , C07K14/435 , G01N27/447 , G01N30/26 , G01N30/88 , G01N33/15
摘要： PROBLEM TO BE SOLVED: To provide an indicator substance for expressing freshness of royal jelly. SOLUTION: It is important to decide an indicator substance for expressing freshness, that is, a criterion of the degree of efficiency and deterioration of itself for every lot in royal jelly products to be compounded in a health food or the like. A protein having a molecular weight of about 350 kilodaltons in royal jelly is used as an indicator substance for freshness. The ratio of the protein in the whole proteins in royal jelly of >=35 wt.% indicates that the royal jelly is fresh.

8. 发明专利

JP2001316400A INDEX SUBSTANCE FOR FRESHNESS OF ROYAL JELLY 失效
公开(公告)号：JP2001316400A
公开(公告)日：2001-11-13
申请号：JP2000326370
申请日：2000-10-26
申请人： POLA CHEM IND INC
发明人： KAMAKURA MASAKI , FUKUDA TOSHIYUKI , MITANI MAKOTO , MIYAZAKI HIROTAKA
IPC分类号： A23L21/20 , C07K14/435 , A23L1/076
摘要： PROBLEM TO BE SOLVED: To obtain an index substance for freshness of royal jelly being the degree of effectiveness of each lot and a standard of deterioration of royal jelly itself in terms of stability of preparation and qualities, especially royal jelly to be added to a health food. SOLUTION: This index substance for freshness of royal jelly is a protein having 57 kilodalton molecular weight in royal jelly.

9. 发明专利

JP2001213792A ANTISTRESS COMPOSITION 失效
公开(公告)号：JP2001213792A
公开(公告)日：2001-08-07
申请号：JP2000324977
申请日：2000-10-25
申请人： POLA CHEM IND INC
发明人： KAMAKURA MASAKI , FUKUDA TOSHIYUKI , MITANI MAKOTO , MIYAZAKI HIROTAKA
IPC分类号： A23L1/30 , A23L21/20 , A23L33/10 , A61K8/64 , A61K8/96 , A61K8/98 , A61K35/64 , A61K35/644 , A61K38/00 , A61P5/42 , A61P5/46 , A61P25/18 , A61P25/20 , A61P35/00 , A61P43/00 , C07K14/435 , A23L1/076 , A61K7/00
摘要： PROBLEM TO BE SOLVED: To provide a means to reduc the cortisol existing amount in blood and to urge anti-stress action or releaving of stress. SOLUTION: A preparation for suppressing the generation of cortisol in blood which is characterized in that whose royal jelly contains more than 9 wt percent of protein of molecular weight of 57 kilo dalton.

10. 发明专利

JP2001029039A PURIFICATION OF ACTIVE INGREDIENT IN ROYAL JELLY 失效
公开(公告)号：JP2001029039A
公开(公告)日：2001-02-06
申请号：JP20268499
申请日：1999-07-16
申请人： POLA CHEM IND INC
发明人： KAMAKURA MASAKI , FUKUDA TOSHIYUKI , MITANI MAKOTO , MIYAZAKI HIROTAKA , FUKUSHIMA MAKOTO
IPC分类号： A23L1/30 , A61K8/96 , A61K8/98 , A61K7/00
摘要： PROBLEM TO BE SOLVED: To raise the concentration of active ingredients in royal jelly and purify the active ingredients so that a more useful royal jelly is obtained by removing water-insoluble ingredients from the royal jelly and then removing high-molecular weight ingredients which are water-soluble ingredients. SOLUTION: Water-insoluble ingredients are removed from royal jelly and high-molecular weight ingredients which are water-soluble ingredients are then removed to purify active ingredients in he royal jelly. A method for adding water to the royal jelly, centrifuging the resultant royal jelly and then providing the supernatant is preferred as the method for removing the water-insoluble ingredients. A method for filtering an aqueous solution through an ultrafiltration membrane for 70,000-150,000 molecular weight, affording a filtrate, then removing the filtered ingredients with an ultrafiltration membrane for 18,000-22,000 molecular weight and concentrating the residual part without passing through the ultrafiltration membrane is preferred as the method for removing the high- molecular weight water-soluble ingredients. A protein having 20,000-100,000 molecular weight which is one of the active ingredients in the royal jelly has antifatigue effects.

你已经成功收藏专利！

检索式保存成功!

IPRDB

热门服务

关于我们

友情链接

联系方式