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1. 发明专利

JP2003048891A 1-alkyl-3h-pyrrolo[2,3-b]pyridines and method for producing the same 审中-公开
标题翻译： 1-烷基-3H-吡咯并[2,3-B]吡啶及其制备方法
公开(公告)号：JP2003048891A
公开(公告)日：2003-02-21
申请号：JP2001233694
申请日：2001-08-01
申请人： Fuji Photo Film Co Ltd , 富士写真フイルム株式会社
发明人： TAKEUCHI KAZUYA
IPC分类号： C07D471/04 , C07D471/10
摘要： PROBLEM TO BE SOLVED: To provide a compound useful as an intermediate for producing a fluorescent dye, and to provide a method for producing the compound.
SOLUTION: This compound comprises a 3H-pyrrolo[2,3-b]pyridine compound expressed by general formula (I) (V
1 , V
2 , and V
3 are each H or a monovalent substituent; X is a hetero-atom or a carbon atom which may be substituted; Y is H or a monvalent substituent; and A is an alkyl which may be substituted, an aryl which may be substituted or a heterocyclic ring which may be substituted) or its salt.
COPYRIGHT: (C)2003,JPO
摘要翻译：要解决的问题：提供可用作荧光染料的中间体的化合物，并提供该化合物的制备方法。解决方案：该化合物包括由通式（I）表示的3H-吡咯并[2,3-b]吡啶化合物（V 1，V 2和V 3）各自为H或一价取代基; X 是可以被取代的杂原子或碳原子; Y是H或一价取代基; A是可被取代的烷基，可被取代的芳基或可以被取代的杂环）或其盐。

2. 发明专利

JP2006022048A Sterilization composition containing hydrophobic peroxy acid and cationic surfactant 审中-公开
标题翻译：含有疏水性过氧酸和阳离子表面活性剂的灭菌组合物
公开(公告)号：JP2006022048A
公开(公告)日：2006-01-26
申请号：JP2004202280
申请日：2004-07-08
申请人： Fuji Photo Film Co Ltd , 富士写真フイルム株式会社
发明人： KAWAKAMI MASAYUKI , KITAGUCHI HIROSHI , TAKEUCHI KAZUYA
IPC分类号： A01N37/16 , A01N25/02 , A01N25/30 , A01N33/12
摘要： PROBLEM TO BE SOLVED: To provide a composition for sterilizing a medical instrument such as an endoscope, etc., in a short time.
SOLUTION: The aqueous composition comprises a hydrophobic peroxy acid (e.g. m-chloroperbenzoic acid or n-pernonanoic acid) and a cationic surfactant (e.g. octadecyldimethylbenzyl ammonium chloride or benzalkonium chloride) and forms a micelle containing the cationic surfactant. At least a part of the hydrophobic peroxy acid is included in the micelle or at least a part of the cationic surfactant and the hydrophobic peroxy acid forms a complex.
COPYRIGHT: (C)2006,JPO&NCIPI
摘要翻译：要解决的问题：提供在短时间内对医疗器械如内窥镜等进行灭菌的组合物。水溶液组合物包含疏水性过氧酸（例如间氯过苯甲酸或正壬酸）和阳离子表面活性剂（例如十八烷基二甲基苄基氯化铵或苯扎氯铵），并形成含有阳离子表面活性剂的胶束。至少一部分疏水性过氧酸被包含在胶束中或至少一部分阳离子表面活性剂中，疏水性过氧酸形成络合物。版权所有（C）2006，JPO＆NCIPI

3. 发明专利

JP2005112783A Malic acid steroid derivative having iodoaryl group 审中-公开
标题翻译：具有IODOARYL组的MALIC ACID STEROID DERIVATIVE
公开(公告)号：JP2005112783A
公开(公告)日：2005-04-28
申请号：JP2003349154
申请日：2003-10-08
申请人： Fuji Photo Film Co Ltd , 富士写真フイルム株式会社
发明人： TAKEUCHI KAZUYA , NISHIGAKI JUNJI , TAKAHASHI KAZUNOBU , AIKAWA KAZUHIRO
IPC分类号： A61K9/127 , A61K47/24 , A61K47/28 , A61K49/04 , A61K51/00 , C07J9/00
摘要： PROBLEM TO BE SOLVED: To provide iodine compounds suitable for use as liposome-containing iodine contrast media for selective contrast imaging of a focus.
SOLUTION: The iodine compounds are malic acid steroid compounds containing 1 to 4 iodoaryl groups or their salt and, for example, are represented by formulae (I) to (III) (wherein Ar
1 and Ar
2 are each an aryl group having at least one iodine as a substituent; L
S , L
1 , and L
2 are each a single bond or a 1-20C divalent connecting bond; A
S , A
1 , and A
2 are each a hetero atom; and Ste is a steroid residue) or their salts.
COPYRIGHT: (C)2005,JPO&NCIPI
摘要翻译：要解决的问题：提供适合用作含脂质体的碘造影剂的碘化合物用于焦点的选择性对比成像。解决方案：碘化合物是含有1至4个碘芳基或其盐的苹果酸类固醇化合物，例如由式（I）至（III）表示（其中Ar 1 和 Ar 2 分别是具有至少一个碘作为取代基的芳基; L 1 ，L 2 < / SP>分别为单键或1-20C二价连接键; A S ，A 1 和A 2 分别为杂原子;和Ste是类固醇残基）或其盐。版权所有（C）2005，JPO＆NCIPI

4. 发明专利

JP2004113145A Method for optically detecting multiple chain nucleic acid 有权
公开(公告)号：JP2004113145A
公开(公告)日：2004-04-15
申请号：JP2002282150
申请日：2002-09-27
申请人： Fuji Photo Film Co Ltd , 富士写真フイルム株式会社
发明人： TAKEUCHI KAZUYA , NAKAMURA TAKEMARE
IPC分类号： G01N33/53 , C12Q1/68 , G01N33/566 , G01N33/58
摘要： PROBLEM TO BE SOLVED: To simply detect a multiple chain nucleic acid in high sensitivity in a neutral to weakly basic pH area used for biochemical examination. SOLUTION: The detection is carried out by bringing a compound emitting substantial fluorescence by mutual action on the multiple chain nucleic acid into contact with the multiple chain nucleic acid. The compound is represented by any of general formulas (I) to (IV) (wherein R 1 and R 3 are each a hydrogen atom or a substituent group; R 4 is an alkyl group; Q is an oxygen atom or an sulfur atom; n is an integer of 0-3; X is a counter ion; q represents a number required for neutralizing an electric charge of molecule; at least one of R 5 , R 7 , R 10 and R 12 represents an electron-donating substituent group in which σp value of Hammett is ≥-1.5 and 6 , R 8 , R 9 and R 11 represent each a hydrogen atom or a monovalent substituent group) and (a) the compound can be kept in substantially colorless and non-fluorescent state in an aqueous solution under conditions protonated in the absence of the multiple chain nucleic acid and (b) the compound is substantially changed to colored state by mutual action to the multiple chain nucleic acid and substantially develops fluorescence by the mutual action when the multiple chain nucleic acid exists under conditions of (a). COPYRIGHT: (C)2004,JPO

5. 发明专利

JP2003246939A METHOD FOR PRODUCING CYANINE DYE 审中-公开
公开(公告)号：JP2003246939A
公开(公告)日：2003-09-05
申请号：JP2002050741
申请日：2002-02-27
申请人： FUJI PHOTO FILM CO LTD
发明人： NAKAMURA TAKEMARE , TAKEUCHI KAZUYA
IPC分类号： C09B23/00
摘要： PROBLEM TO BE SOLVED: To provide a method for producing a cyanine dye, by which the cyanine dye having a neutral chromophore can simply and easily be synthesized. SOLUTION: This method for producing the cyanine dye having the neutral chromophore comprises a process for removing at least one of substituted alkyl groups of the cyanine dye having a cationic chromophore [at least one of substituents bound to ring-forming nitrogen atoms contained in the chromophore of the dye is a substituted alkyl group represented by general formula (I): Si(R 1 )(R 2 )(R 3 )-C(R 4 )(R 5 )-C(R 6 R 7 )-* (R 1 to R 3 are each an alkyl or aryl; R 4 to R 7 are H or a substituent, where * shows a position bound to the ring-forming nitrogen atom contained in the chromophore)] in the presence of a fluoride ion. COPYRIGHT: (C)2003,JPO

6. 发明专利

JP2003240780A OPTICAL MEASURING METHOD FOR MULTIPLE CHAIN NUCLEIC ACID 审中-公开
公开(公告)号：JP2003240780A
公开(公告)日：2003-08-27
申请号：JP2002036473
申请日：2002-02-14
申请人： FUJI PHOTO FILM CO LTD
发明人： NAKAMURA TAKEMARE , TAKEUCHI KAZUYA
IPC分类号： G01N33/50 , C12N15/09 , C12Q1/68 , G01N21/78
摘要： PROBLEM TO BE SOLVED: To provide a method by which a multiple chain nucleic acid is optically measured. SOLUTION: The method of optically measuring the multiple chain nucleic acid is a method which contains a process of bringing a compound capable of interacting with the multiple chain nucleic acid into contact with the multiple chain nucleic acid, and in which the compound is a compound having the following properties: (a) a property that the compound can exist in a substantially colorless and nonfluorescent state in an aqueous solution under at least one condition when the multiple chain nucleic acid does not exist; and (b) a property that, when the multiple chain nucleic acid exists under a condition of (a), the compound is substantially colored due to its interaction with the multiple chain nucleic acid, and that it substantially reveals fluorescence due to the interaction. COPYRIGHT: (C)2003,JPO

7. 发明专利

JP2003064083A 2,3,3-TRIMETHYL-3H-PYRROLO[2,3-b]PYRIDINE-5-SULFONIC ACID AND DERIVATIVE THEREOF 审中-公开
标题翻译： 2,3,3-三甲基-3H-吡咯并[2,3-b]吡啶-5-磺酸及其衍生物
公开(公告)号：JP2003064083A
公开(公告)日：2003-03-05
申请号：JP2001252788
申请日：2001-08-23
申请人： Fuji Photo Film Co Ltd , 富士写真フイルム株式会社
发明人： NAKAMURA TAKEMARE , TAKEUCHI KAZUYA
IPC分类号： C07D471/04 , C07D519/00 , C09B23/00 , C09K11/06
摘要： PROBLEM TO BE SOLVED: To obtain an azacyanine coloring matter having high fluorescence intensity and high water solubility.
SOLUTION: This compound is represented by general formula (I) or general formula (II) (M is a hydrogen atom or a countercation of sulfonic acid anion in the general formula (I); R is a ≤10C substituted or nonsubstituted alkyl group in the general formula (II)) or its salt.
COPYRIGHT: (C)2003,JPO
摘要翻译：要解决的问题：获得具有高荧光强度和高水溶性的氮杂菁色素。解决方案：该化合物由通式（I）或通式（II）表示（M是通式（I）中的氢原子或磺酸阴离子的反应物; R是<= 10取代或未取代的烷基在通式（II）中）或其盐。

8. 发明专利

JP2003040889A Sulfonated 3h-pyrollo[2,3-b]pyridines and method of producing the same 审中-公开
标题翻译：磺化3H-吡咯并[2,3-B]吡啶及其生产方法
公开(公告)号：JP2003040889A
公开(公告)日：2003-02-13
申请号：JP2001232277
申请日：2001-07-31
申请人： Fuji Photo Film Co Ltd , 富士写真フイルム株式会社
发明人： TAKEUCHI KAZUYA
IPC分类号： C07D471/04
摘要： PROBLEM TO BE SOLVED: To provide a compound that is useful as an intermediate for fluorescent dyes, and a method of producing the same.
SOLUTION: The compound is 3H-pyrollo[2,3-b]pyridine represented by general formula (I) (wherein V
1 , V
2 and V
3 are individually independent and mean H or a monovalent substituent; R
1 and R
2 are each an alkyl which may be substituted or may link to each other to form a ring which may be substituted; M is H or a cation).
COPYRIGHT: (C)2003,JPO
摘要翻译：要解决的问题：提供可用作荧光染料中间体的化合物及其制备方法。溶液：该化合物是由通式（I）表示的3H-吡咯并[2,3-b]吡啶（其中V 1，V 2和V 3各自独立地表示H或一价取代基; R 1和R 2各自是可以被取代或可以彼此连接以形成可以被取代的环的烷基; M是H或阳离子）。

9. 发明专利

JP2006176442A Composition for sterilization containing glycoconjugate having peroxycarboxy group 审中-公开
标题翻译：含有过氧化碳组的甘氨酸钠灭菌组合物
公开(公告)号：JP2006176442A
公开(公告)日：2006-07-06
申请号：JP2004371333
申请日：2004-12-22
申请人： Fuji Photo Film Co Ltd , 富士写真フイルム株式会社
发明人： TAKEUCHI KAZUYA , KAWAKAMI MASAYUKI
IPC分类号： C07H7/033 , A01N25/02 , A01N25/22 , A01N25/30 , A01N43/16
摘要： PROBLEM TO BE SOLVED: To provide a new compound usable as an active ingredient of a composition capable of sterilizing equipment for medical care such as an endoscope, and having low smell; and to provide the composition containing the compound.
SOLUTION: The glycoconjugate (e.g. peroxy D-glucuronic acid) having a peroxycarboxy group, the aqueous composition containing the glycoconjugate, and the method for producing the glycoconjugate having the peroxycarboxy group, comprising a step for mixing the glycoconjugate having a carboxy group with an aqueous solution containing hydrogen peroxide are provided.
COPYRIGHT: (C)2006,JPO&NCIPI

10. 发明专利

JP2006069894A Carboxylic acid ester containing triiodoaryl group 审中-公开
标题翻译：含有TRIIODOARYL集团的羧酸酯
公开(公告)号：JP2006069894A
公开(公告)日：2006-03-16
申请号：JP2004251279
申请日：2004-08-31
申请人： Fuji Photo Film Co Ltd , 富士写真フイルム株式会社
发明人： TAKAHASHI KAZUNOBU , NISHIGAKI JUNJI , AIKAWA KAZUHIRO , TAKEUCHI KAZUYA
IPC分类号： C07C69/736 , A61K9/127 , A61K49/04 , C07C309/12 , C07D295/08
摘要： PROBLEM TO BE SOLVED: To obtain an iodine compound suitable as a liposome-containing iodine contrast medium for lesion-selective contrastradiography. SOLUTION: The liposome comprises a compound represented by general formula (I) (Ar is an aryl group containing at least three iodine atoms; A is O or CH 2 ; n is an integer of 5-15; R 1 is a 1-6C saturated or unsaturated group) or its salt as a film constituent component. The X-ray contrast medium comprises the liposome. COPYRIGHT: (C)2006,JPO&NCIPI

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