专利快速检索-快速检索全球专利，免费商用专利数据库-IPRDB

1. 发明专利

JP2004003898A Measuring instrument for ionic activity 审中-公开
标题翻译：测量离子活性仪器
公开(公告)号：JP2004003898A
公开(公告)日：2004-01-08
申请号：JP2002161006
申请日：2002-06-03
申请人： Fuji Photo Film Co Ltd , 富士写真フイルム株式会社
发明人： TERAJIMA MASAAKI , SESHIMOTO OSAMU , ARAI FUMITADA , TAKAHASHI SHUICHI
IPC分类号： G01N33/483 , G01N27/333 , G01N27/416 , G01N33/487
摘要： PROBLEM TO BE SOLVED: To provide a measuring instrument for ionic activity, capable of stably measuring ionic activities. SOLUTION: In the measuring instrument for ionic activity, a top side frame body made of an insulating material is provided with a drip opening for the liquid to be tested; a drip opening for a reference solution; and a bridge for providing electrical continuity, between the liquid to be tested and the reference solution provided for each drip opening. A bottom side frame body, made of an insulating material, is provided with both a passage for the liquid to be tested and a passage for the reference solution for making them flow, while the liquid to be tested and the reference solution provided for each drip opening are separated from each other. At least a pair of ion-selective electrodes are arranged in between the top side frame body and the bottom side frame body, and a conductive member is provided between the top side frame body and the bottom side frame body, with its part exposed to the outside of the measuring instrument. COPYRIGHT: (C)2004,JPO
摘要翻译：要解决的问题：提供能够稳定地测量离子活性的离子活性测量仪器。解决方案：在用于离子活性的测量仪器中，由绝缘材料制成的顶侧框架体设置有待测试液体的滴水口; 用于参考溶液的滴水口; 以及用于在要测试的液体和为每个滴水口提供的参考溶液之间提供电连续性的桥。由绝缘材料制成的底侧框体具有用于待测试液体的通道和用于使其流动的参考溶液的通道，同时为每个滴液提供待测试的液体和参考溶液开口彼此分开。至少一对离子选择电极布置在顶侧框架体和底侧框架体之间，并且导电构件设置在顶侧框架体和底侧框架体之间，其部分暴露于在测量仪器外面。版权所有（C）2004，JPO

2. 发明专利

JP2003014744A Reactive solid-phase carrier and dna fragment detecting tool 有权
标题翻译：反应固相载体和DNA片段检测工具
公开(公告)号：JP2003014744A
公开(公告)日：2003-01-15
申请号：JP2001168982
申请日：2001-06-05
申请人： Fuji Photo Film Co Ltd , 富士写真フイルム株式会社
发明人： SHINOKI HIROSHI , SESHIMOTO OSAMU
IPC分类号： G01N33/53 , C12M1/00 , C12N15/09 , C12Q1/68 , G01N33/547 , G01N33/552 , G01N33/553 , G01N37/00
摘要： PROBLEM TO BE SOLVED: To provide a fixing method by which a pre-prepared DNA fragment, a nucleotide derivative such as the oligonucleotide, etc., or its analogue can be fixed densely and stably to the surface of a solid-state carrier through a quick reaction, a method of manufacturing a carrier for fixing the nucleotide derivative or its analogue utilizing the fixing method, and a detecting tool for detecting nuclei acid fragment samples, etc., represented by a DNA chip. SOLUTION: A reactive solid-phase carrier is constituted by fixing a group of vinylsulfonyl radicals or their reactive precursor radicals to the rugged surface of the solid-phase carrier by using a divinylsulfon compound, etc., by performing covalent coupling through their coupling radicals. The nuclei acid fragment sample detecting and fixing tool is constituted by coupling and fixing the nucleotide derivative, such as the oligonucleotide, polynucleotide, peptide nuclei acid, etc., or its analogue to the reactive solid-phase carrier by performing covalent coupling.
摘要翻译：要解决的问题：提供一种固定方法，其中通过以下步骤可以将预先制备的DNA片段，寡核苷酸等核苷酸衍生物或其类似物密集且稳定地固定在固态载体的表面快速反应，利用定影方法制造用于固定核苷酸衍生物或其类似物的载体的方法，以及用于检测由DNA芯片表示的核酸片段样品等的检测工具。解决方案：通过使用二乙烯基砜化合物等将一组乙烯基磺酰基或其反应性前体基团固定在固相载体的粗糙表面上，通过其偶联基团进行共价偶联来构成反应性固相载体。核酸片段样品检测和固定工具通过共价偶联将核苷酸衍生物如寡核苷酸，多核苷酸，肽核酸等或其类似物与反应性固相载体偶联和固定而构成。

3. 发明专利

JP2002365291A METHOD FOR MANUFACTURING IMPLEMENT FOR DETECTING REACTIVE NUCLEIC ACID FRAGMENT AND COMPLEMENTARY DNA FRAGMENT 失效
公开(公告)号：JP2002365291A
公开(公告)日：2002-12-18
申请号：JP2001173064
申请日：2001-06-07
申请人： FUJI PHOTO FILM CO LTD
发明人： SHINOKI HIROSHI , IWAKI YOSHIHIDE , SESHIMOTO OSAMU
IPC分类号： G01N33/53 , C12M1/00 , C12N15/09 , C12Q1/68 , G01N37/00
摘要： PROBLEM TO BE SOLVED: To provide a detecting implement represented by a DNA chip which improves reactivity between nucleic acid fragments (probe molecules) and a surface of a solid-phase carrier and is highly stable. SOLUTION: By bringing a group of the reactive nucleic acid fragments bonded with vinyl sulfonyl groups by covalent bonding into contact with the solid-phase carrier provided with a group of reactive groups, the solid-phase carrier in which the nucleic acid fragments are bonded and fixed to the surface via connecting groups with sulfonyl groups is manufactured in this method.

4. 发明专利

JP2002360257A METHOD FOR DETECTING GENE IN DNA MICROARRAY 失效
公开(公告)号：JP2002360257A
公开(公告)日：2002-12-17
申请号：JP2001169317
申请日：2001-06-05
申请人： FUJI PHOTO FILM CO LTD
发明人： IWAKI YOSHIHIDE , SHINOKI HIROSHI , SESHIMOTO OSAMU
IPC分类号： C12N15/09 , C12P19/34 , C12Q1/68 , C40B40/06 , C40B60/14
摘要： PROBLEM TO BE SOLVED: To provide a means for readily carrying out a genetic analysis without carrying out complex operation. SOLUTION: This method for detecting the nucleic acid comprises a step for carrying out a PCR reaction or a reverse transcription reaction by adding a template nucleic acid on a solid carrier having an immobilized nucleic acid, and a step for hybridizing the nucleic acid immobilized on the solid carrier with the nucleic acid synthesized by the PCR reaction or the transverse transcription reaction.

5. 发明专利

JP2001128697A DNA FRAGMENT IMMOBILIZED SOLID-PHASE CARRIER, METHOD FOR IMMOBILIZING DNA FRAGMENT AND METHOD FOR DETECTING NUCLEIC ACID FRAGMENT 失效
公开(公告)号：JP2001128697A
公开(公告)日：2001-05-15
申请号：JP31629599
申请日：1999-11-08
申请人： FUJI PHOTO FILM CO LTD
发明人： SHINOKI HIROSHI , SUDO YUKIO , SESHIMOTO OSAMU
IPC分类号： C12N15/09 , C12M1/00 , C12M1/40 , C12Q1/68 , G01N33/53 , G01N37/00
摘要： PROBLEM TO BE SOLVED: To provide an immobilization method capable of bonding a previously prepared DNA fragment to the surface of a solid carrier by a quick reaction and making a reaction product stably maintain a bond, to obtain a DNA fragment immobilized solid-phase carrier and to provide a method for detecting a nucleic acid fragment. SOLUTION: This DNA fragment immobilized solid-phase carrier is characterized in that the DNA fragment is immobilized through a triazine group to the surface of a solid-phase carrier.

6. 发明专利

JP2001108683A DNA FRAGMENT FIXING SOLID-PHASE CARRIER, DNA FRAGMENT FIXING METHOD, AND NUCLEIC-ACID FRAGMENT DETECTING METHOD 失效
公开(公告)号：JP2001108683A
公开(公告)日：2001-04-20
申请号：JP29214199
申请日：1999-10-14
申请人： FUJI PHOTO FILM CO LTD
发明人： SHINOKI HIROSHI , SUDO YUKIO , SESHIMOTO OSAMU
IPC分类号： C12N15/09 , C12Q1/68 , G01N33/53 , G01N33/566 , G01N37/00
摘要： PROBLEM TO BE SOLVED: To provide a fixing method for bringing a previously prepared DNA fragment on the surface of a solid-phase carrier into a covalent bond by a simple and inexpensive method, a DNA chip, and a method for detecting a nucleic acid fragment. SOLUTION: In this DNA fragment fixing solid-phase carrier, a DNA fragment is fixed via an amide bond to chain molecules fixed to the surface of a solid-phase carrier at one terminal. In this method for fixing a DNA fragment to the surface of a solid-phase carrier, a process to form a connecting radical, which is bonded with chain molecules with a carboxylic acid radical at a free terminal at the terminal on the other side, in the surface of a solid-phase carrier and a process to form an amide bond by bringing the carboxylic acid radical of the connecting radical into reaction with the amide radical of the DNA fragment with an amino radical at one terminal are sequentially performed, and chain molecules with a carboxylic acid radical at a free terminal are prepared by bringing an amino radial, which is introduced by bringing a silane coupling agent with an amino radical into contact with the surface of a solid-phase carrier, into reaction with succinic anhydride. A DNA fragment with known base sequence is used. In this method for detecting a nucleic acid fragment with complementarity to a DNA fragment fixed to the DNA-fragment fixing solid- phase carrier, an aqueous solution formed by dissolving or dispersing a nucleic acid fragment sample labeled with a fluorescent substance is dropped to the DNA fragment fixing solid-phase carrier and incubated to detect hybrid DNA formed of the DNA fragment and nucleic acid fragment sample fixed to the DNA fragment fixing solid-phase carrier.

7. 发明专利

JP2000241408A BLOOD FILTER 失效
公开(公告)号：JP2000241408A
公开(公告)日：2000-09-08
申请号：JP4663399
申请日：1999-02-24
申请人： FUJI PHOTO FILM CO LTD
发明人： ARAI TAKAYOSHI , YAZAWA KENICHIRO , SESHIMOTO OSAMU
IPC分类号： G01N33/48
摘要： PROBLEM TO BE SOLVED: To easily filter a total amount of blood after sampling in a simple structure, by partitioning the inside of a cylindrical vessel having a plug capable of insertion of a needle at an opening end into two cylindrical chambers with a blood filtering material. SOLUTION: In this blood filter, a rubber plug 6 is mounted to one opening end of a polystyrene-made cylindrical vessel 5 and a plate-shaped lid 7 is mounted to the other end, and the cylindrical vessel 5 is partitioned by a blood filtering material 2 into a blood chamber 8 and a filtering liquid chamber 9 whose volumes are 3 ml. The blood filtering material 2 is formed by piling six glass fiber filter sheets and piling one polysulfone film on the filtering liquid chamber 9 side, and it is supported by a polystyrene-made frame 1 melted with the inner wall of the cylindrical vessel 5. When blood is directly sampled from a blood vessel into this blood filter and then the blood filter is put down to open the rear end of a needle 10, air flows into the depressed blood chamber 8 to filter the blood. After the blood filtration, the blood filter is put down to be returned to an original position, the plate-shaped lid 7 is removed, and blood plasma obtained by the filtration is sampled to be used for analysis. Thus, a total amount of the sampled blood can be filtered.

8. 发明专利

JP2000221188A BLOOD FILTERING DEVICE 失效
公开(公告)号：JP2000221188A
公开(公告)日：2000-08-11
申请号：JP2456899
申请日：1999-02-02
申请人： FUJI PHOTO FILM CO LTD
发明人： ARAI TAKAYOSHI , YAZAWA KENICHIRO , SESHIMOTO OSAMU
IPC分类号： A61B5/15 , A61M1/02 , A61M1/34 , B01D33/15 , G01N1/10 , G01N33/48
摘要： PROBLEM TO BE SOLVED: To filter blood easily in a simple structure, regardless of the passage of time after blood collection by using a blood container with a tubular part and a blood filtering material which moves forward in the tubular part to filter blood, while preventing the passage of blood corpuscles. SOLUTION: A means to press down a frame body 1 for filtering blood is necessary. A rod or the like to press down the frame body 1 is provided as the means, or the frame body 1 is made of a ferromagnetic material and is moved by a magnetic force from the outside, etc. In a filtering method, by putting blood in a blood container 6 up to its tubular part and then inserting and pressing down a blood filtering material 2 into the container 6, blood plasma or serum is obtained above the filtering material 2 as a filtrate. The filtrate is collected and subjected to analysis, etc. Six pieces of glass fiber filter paper are laminated, and one polysulfone film is laminated on them and is used as the filtering material 2. 3.0 ml of blood is put into the blood collecting tube 6, the filtering material 2 is inserted into the blood collecting tube 6 from its opening and is pressed down by a pressing rod 7. As a result, filtration is performed to separate blood plasma above the filtering material 2 and blood corpuscles are gathered beneath the filtering material 2.

9. 发明专利

JP2000221155A SILVER/SILVER HALIDE REFERENCE ELECTRODE, ITS FORMATION AND ION-SELECTIVE ELECTRODE 失效
公开(公告)号：JP2000221155A
公开(公告)日：2000-08-11
申请号：JP2414399
申请日：1999-02-01
申请人： FUJI PHOTO FILM CO LTD
发明人： TERAJIMA MASAAKI , ITO TOSHIFURU , SESHIMOTO OSAMU
IPC分类号： G01N27/30 , G01N27/403
摘要： PROBLEM TO BE SOLVED: To restrict a mixture of heavy metal elements into a generated silver halide layer and correctly determine a specific ion activity by oxidizing a surface of a silver layer by a chelated iron (III) salt in the presence of a halide. SOLUTION: In order to halogenate a silver layer surface, a nonconductive supporting body coated with silver is dipped in a reaction bath with a chelated iron (III) salt and a halide. A concentration of the iron salt in the reaction bath is preferably in the range of 100-500 mM and more preferably in the range of 150-250 mM. After the dipping, the supporting body is washed with water and dried. A chelating agent used is preferably an amino-carboxylic acid compound such as propanediamine tetraacetic acid(PDTA), ethylenediamine tetraacetic acid(EDTA) or the like. Mixture of heavy metal elements (e.g. iron element) in the silver halide is nearly avoided and effects of interfering ions included in a sample can be eliminated.

10. 发明专利

JP2000180443A RECOVERY METHOD OF HAEMOFILTRATION RESIDUE 失效
公开(公告)号：JP2000180443A
公开(公告)日：2000-06-30
申请号：JP35547598
申请日：1998-12-15
申请人： FUJI PHOTO FILM CO LTD
发明人： SESHIMOTO OSAMU , YAZAWA KENICHIRO , ARAI TAKAYOSHI
IPC分类号： B01D29/01 , B01D29/66 , B01D29/94 , B01D39/20 , B01D61/14 , B01D61/18 , G01N1/28 , G01N33/48 , G01N33/49
摘要： PROBLEM TO BE SOLVED: To provide a method of preparing sample of corpuscles which can be carried out with a simple means and less deformation, and moreover, easy observed. SOLUTION: A hemofilter herein used comprises a haemofiltration material 30 made of a volumetric filtering material and a holder 10 which houses the material and has a blood inlet 14 and a filter liquid outlet 28. After the haemofiltration by using the hemofilter, a filtration residue is recovered as accumulated on the haemofiltration material 30 adapted to let recovery water pass from the side of the filter liquid outlet.

你已经成功收藏专利！

检索式保存成功!

IPRDB

热门服务

关于我们

友情链接

联系方式