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1. 发明专利

JP2009143874A Oral care product 审中-公开
标题翻译：口腔护理产品
公开(公告)号：JP2009143874A
公开(公告)日：2009-07-02
申请号：JP2007324573
申请日：2007-12-17
申请人： Chisso Corp , チッソ株式会社
发明人： ONCHI YUICHI , YOSHIDA NAOYUKI
IPC分类号： A61K8/64 , A23L1/30 , A61K8/19 , A61K8/24 , A61K8/34 , A61K8/365 , A61K8/60 , A61K8/89 , A61Q11/00
摘要： PROBLEM TO BE SOLVED: To provide an oral care product having excellent prophylactic effects on dental caries without containing a fluoride. SOLUTION: The oral care product comprises bisphosphonylated-ε-polylysine. The oral care product is prepared by using the bisphosphonylated-ε-polylysine, hydroxyapatite, and xylitol in combination. The oral care product is prepared by using the bisphosphonylated-ε-polylysine, trehalose and a sugar alcohol in combination. The oral care product is prepared by using the bisphosphonylated-ε-polylysine, and a nonreactive silicone compound in combination. The oral care product is prepared by using the bisphosphonylated-ε-polylysine, and a potassium ion or a strontium ion, or a mixture thereof in combination. The oral care product is prepared by using the bisphosphonylated-ε-polylysine, and a soluble calcium metal ion sequestering agent not being an oxidizing agent in combination. COPYRIGHT: (C)2009,JPO&INPIT
摘要翻译：待解决的问题：提供对不含氟化物的龋齿具有优异预防效果的口腔护理产品。口服护理产品包含双膦酰化ε-聚赖氨酸。通过组合使用双膦酰化ε-聚赖氨酸，羟基磷灰石和木糖醇制备口腔护理产品。通过组合使用双膦酰化ε-聚赖氨酸，海藻糖和糖醇制备口腔护理产品。通过使用双膦酰化ε-聚赖氨酸和非反应性硅氧烷化合物组合来制备口腔护理产品。通过组合使用双膦酰化ε-聚赖氨酸，钾离子或锶离子或其混合物来制备口腔护理产品。通过使用双膦酰化ε-聚赖氨酸和不是氧化剂的可溶性钙金属离子螯合剂组合来制备口腔护理产品。版权所有（C）2009，JPO＆INPIT

2. 发明专利

JP2009114261A Uremia therapeutic drug and uremia therapeutic food 审中-公开
标题翻译： UREMIA治疗药物和UREMIA治疗食品
公开(公告)号：JP2009114261A
公开(公告)日：2009-05-28
申请号：JP2007286318
申请日：2007-11-02
申请人： Chisso Corp , Otsuka Pharmaceut Factory Inc , チッソ株式会社 , 株式会社大塚製薬工場
发明人： YAMAOKA IPPEI , YOSHIDA NAOYUKI , ISHIDA KAZUFUMI , SASAKI SHUJI , YAMAMOTO YUICHI
IPC分类号： C08B15/10 , A23L1/30 , A61K31/737 , A61P13/12
摘要： PROBLEM TO BE SOLVED: To provide a uremia therapeutic drug and uremia therapeutic food. SOLUTION: In the uremia therapeutic drug, a metal salt of a crosslinked cellulose derivative represented by the following general formula (I) is an active ingredient. In the formula R-O-A (I), R represents a crosslinked cellulose residue, A represents a functional group (a) having cation exchangeability. The functional group having cation exchangeability is a sulfonic acid group, a carboxyl group, a phosphoric acid group, and the like. A concrete compound for the crosslinked cellulose derivative includes a sulfated cellulose calcium salt and the like. COPYRIGHT: (C)2009,JPO&INPIT
摘要翻译：要解决的问题：提供尿毒症治疗药物和尿毒症治疗食品。解决方案：在尿毒症治疗药物中，由以下通式（I）表示的交联纤维素衍生物的金属盐是活性成分。在式R-O-A（I）中，R表示交联的纤维素残基，A表示具有阳离子交换性的官能团（a）。具有阳离子交换性的官能团是磺酸基，羧基，磷酸基等。交联纤维素衍生物的具体化合物包括硫酸化纤维素钙盐等。版权所有（C）2009，JPO＆INPIT

3. 发明专利

JP2008266334A New process for producing neplanocin a and intermediate 有权
标题翻译：生产NEPLANOCIN A和中间体的新工艺
公开(公告)号：JP2008266334A
公开(公告)日：2008-11-06
申请号：JP2008107462
申请日：2008-04-17
申请人： Chisso Corp , チッソ株式会社
发明人： YOSHIDA NAOYUKI , OGASAWARA KUNIRO
IPC分类号： C07D473/34 , C07C35/37 , C07C49/643 , C07C69/00 , C07D303/32 , C07D307/77 , C07D317/70 , C07D473/00 , C07D493/08 , C07F7/08 , C07F7/10 , C07F7/18
CPC分类号： C07D307/77 , C07B2200/07 , C07C29/147 , C07C35/37 , C07C49/643 , C07C69/013 , C07C69/16 , C07C2603/68 , C07D303/32 , C07D317/70 , C07D473/00 , C07D493/08 , C07F7/1856 , C12P7/62 , C12P15/00 , C12P41/004 , C07C35/26
摘要： PROBLEM TO BE SOLVED: To provide a new process for producing neplanocin A and a new compound group useful as intermediates thereof.
SOLUTION: Neplanocin A is obtained by starting from optically active 2-hydroxymethyl-5-hydroxy-tricyclo [5.2.1.0
2,6 ] deca-3,8-diene and via a key reaction comprising a retro-Diels-Alder reaction of 2-(t-butyldimethylsilyloxymethyl)-3,4-[(dimethylmethylene)dioxy]-5-hydroxy-tricyclo [5.2.1.0
2,6 ] deca-8-ene. Neplanocin A can be manufactured much more efficiently than conventional cases by this process.
COPYRIGHT: (C)2009,JPO&INPIT
摘要翻译：要解决的问题：提供一种新的制备尼泊洛环素A和用作其中间体的新化合物的方法。解决方案：通过从光学活性的2-羟甲基-5-羟基 - 三环[5.2.1.0＆lt; SP＆gt;]癸烷-3,8-二烯开始并通过关键反应获得Neplanocin A 包括2-（叔丁基二甲基甲硅烷氧基甲基）-3,4 - [（二甲基亚甲基）二氧基] -5-羟基 - 三环[5.2.1.0 SP2 2,6]癸烷的逆Diels-Alder反应， 8烯。通过该方法可以比常规病例更有效地制造Neplanocin A。版权所有（C）2009，JPO＆INPIT

4. 发明专利

JP2005112762A Skin care preparation for external use 有权
标题翻译：皮肤护理准备外用
公开(公告)号：JP2005112762A
公开(公告)日：2005-04-28
申请号：JP2003347814
申请日：2003-10-07
申请人： Chisso Corp , チッソ株式会社
发明人： TAKIGAMI SHOJI , YOSHIDA NAOYUKI , IKEDA TAKUO , ISHIDA KAZUFUMI , SAWAI TOSHIYA
IPC分类号： A61K31/736 , A61P17/00 , C08B37/00
摘要： PROBLEM TO BE SOLVED: To provide a skin care preparation for external use which is inexpensive, is readily produced, has low irritation to the skin and exhibits excellent antiinflammation action and in which a raw material is readily obtained and a mammal-derived component is not used as a raw material.
SOLUTION: This preparation contains sulfated glucomannan and/or its salt. The preparation contains 0.001-5 wt.% of the sulfated glucomannan and/or its salt.
COPYRIGHT: (C)2005,JPO&NCIPI
摘要翻译：待解决的问题：为了提供廉价的，易于生产的外用皮肤护理制剂，对皮肤的刺激性低并且表现出优异的抗炎作用，并且其中易于获得原料和哺乳动物来源的组分不用作原料。
解决方案：该制剂含有硫酸化葡甘露聚糖和/或其盐。该制剂含有0.001-5重量％的硫酸化葡甘露聚糖和/或其盐。版权所有（C）2005，JPO＆NCIPI

5. 发明专利

JP2008266265A Antiviral agent 审中-公开
标题翻译：抗病毒剂
公开(公告)号：JP2008266265A
公开(公告)日：2008-11-06
申请号：JP2007114807
申请日：2007-04-24
申请人： Chisso Corp , Kokuritsu Iyakuhin Shokuhin Eisei Kenkyusho , チッソ株式会社 , 国立医薬品食品衛生研究所長
发明人： TANAMOTO KENICHI , USHIJIMA KOJI , YOSHIDA NAOYUKI , ISHIDA KAZUFUMI
IPC分类号： A61K31/737 , A61P31/12 , A61P31/18 , C08B5/14 , C08B37/00
摘要： PROBLEM TO BE SOLVED: To provide an antiviral agent which has reduced cytotoxicity, is available at a low cost and thus is different from conventional ones, though many antiviral actions by sulfated polysaccharides such as heparin have been investigated.
SOLUTION: The antiviral agent contains a sulfated polysaccharide prepared by using a plant-originated polysaccharide such as cellulose or glucomannan, and sulfating 6-100% of the hydroxy groups of the raw material polysaccharide or a compound having the sulfated polysaccharide as a partial structure, especially cellulose sulfate or glucomannan sulfate.
COPYRIGHT: (C)2009,JPO&INPIT
摘要翻译：要解决的问题：为了提供具有降低的细胞毒性的抗病毒剂，可以低成本获得，因此与常规的不同，尽管已经研究了硫酸多糖如肝素的许多抗病毒作用。解决方案：抗病毒剂含有通过使用植物来源的多糖如纤维素或葡甘露聚糖制备的硫酸化多糖，并且将原料多糖的6-100％的羟基硫酸化或具有硫酸化多糖的化合物作为部分结构，特别是硫酸纤维素或硫酸葡甘露聚糖。版权所有（C）2009，JPO＆INPIT

6. 发明专利

JP2007182431A Antifouling agent 有权
标题翻译：防伪代理
公开(公告)号：JP2007182431A
公开(公告)日：2007-07-19
申请号：JP2006323653
申请日：2006-11-30
申请人： Chisso Corp , チッソ株式会社
发明人： YAMAMOTO YUICHI , HIRAKI JUN , YOSHIDA NAOYUKI
IPC分类号： A01N55/00 , A01N61/00 , A01P3/00 , C09D5/16 , C09D183/08 , C09D189/00
摘要： PROBLEM TO BE SOLVED: To provide an antifouling agent having an antibacterial activity against a wide variety of bacteria, also having an attachment-repelling activity against algae and aquatic organisms, having high solubility to organic solvents, thereby excellent in compatibility to resins and having high safety.
SOLUTION: This antifouling composition is constituted by using a silicone-modified antibacterial polymer consisting of an amino group-containing antibacterial polymer introduced with a polyorganosiloxane group, as an active ingredient.
COPYRIGHT: (C)2007,JPO&INPIT
摘要翻译：要解决的问题：提供对各种细菌具有抗菌活性的防污剂，其还具有对藻类和水生生物的附着排斥活性，对有机溶剂的溶解度高，因此与树脂的相容性优异安全性高。解决方案：该防污组合物由使用由聚有机硅氧烷基引入的含氨基的抗菌聚合物组成的硅氧烷改性的抗菌聚合物作为活性成分构成。版权所有（C）2007，JPO＆INPIT

7. 发明专利

JP2007039428A Body weight gain inhibitor 审中-公开
标题翻译：身体重量增加抑制剂
公开(公告)号：JP2007039428A
公开(公告)日：2007-02-15
申请号：JP2006037775
申请日：2006-02-15
申请人： Chisso Corp , Ehime Univ , チッソ株式会社 , 国立大学法人愛媛大学
发明人： TSUJITA TAKAHIRO , TAKAKU TAKESHI , YOSHIDA NAOYUKI
IPC分类号： A61K31/785 , A21D13/08 , A23D7/00 , A23G1/00 , A23G1/30 , A23G3/34 , A23G4/00 , A23L1/05 , A23L1/305 , A23L2/52 , A61K9/08 , A61K9/14 , A61K9/20 , A61K9/48 , A61P3/04 , A61P3/06 , A61P3/10 , A61P9/12
CPC分类号： A61K38/10 , A23G1/44 , A23G3/44 , A23G4/14 , A23L2/52 , A23L33/18 , A23P10/28 , A23P10/30 , A23V2002/00 , A61K38/16 , A23V2200/332 , A23V2250/063 , A23V2250/156 , A23V2250/70 , A23V2250/5118 , A23V2250/5108 , A23V2250/54246 , A23V2250/628
摘要： PROBLEM TO BE SOLVED: To provide a body weight gain inhibitor that can be safely given for a long period of time and a food composition having body weight gain inhibitory action or the like. SOLUTION: The body weight gain inhibitor includes ε-polylysine or a salt thereof and a food composition having the body weight gain action or the like are used therefor. COPYRIGHT: (C)2007,JPO&INPIT
摘要翻译：待解决的问题：提供长时间安全地给予的体重增加抑制剂和具有体重增加抑制作用的食物组合物等。解决方案：使用体重增加抑制剂包括ε-聚赖氨酸或其盐，并且使用具有体重增加作用的食物组合物等。版权所有（C）2007，JPO＆INPIT

8. 发明专利

JP2006307004A Hydrogel comprising polyamino acid as constituent component 审中-公开
标题翻译：包含聚氨酯酸的水合物作为组分成分
公开(公告)号：JP2006307004A
公开(公告)日：2006-11-09
申请号：JP2005131336
申请日：2005-04-28
申请人： Chisso Corp , Osaka Univ , チッソ株式会社 , 国立大学法人大阪大学
发明人： UYAMA HIROSHI , YOSHIDA NAOYUKI
IPC分类号： C08G69/48 , A61K8/02 , A61K8/72 , A61K8/96 , A61K9/06 , A61K47/42 , A61L15/16
摘要： PROBLEM TO BE SOLVED: To provide a cross-linked hydrogel produced from two or more kinds of polyamino acid materials having different charges, producible under mild conditions and having excellent biocompatibility and biodegradability.
SOLUTION: The cross-linked hydrogel is obtained by condensing a cationic polyamino acid having ≥5 degree of polymerization or its salt with an anionic polyamino acid or its salt. Furthermore, a method for producing the cross-linked hydrogel is provided.
COPYRIGHT: (C)2007,JPO&INPIT
摘要翻译：要解决的问题：提供由两种或更多种具有不同电荷的聚氨基酸材料制备的交联水凝胶，其可在温和条件下生产并且具有优异的生物相容性和生物降解性。解决方案：交联水凝胶通过将具有≥5聚合度的阳离子聚氨基酸或其盐与阴离子聚氨基酸或其盐缩合而获得。另外，提供了交联水凝胶的制造方法。版权所有（C）2007，JPO＆INPIT

9. 发明专利

JP2006274245A Compound selected from sulfated cellulose and its salt and dermatitis therapeutic agent 有权
标题翻译：从硫酸纤维素及其盐和药物治疗剂中选择的化合物
公开(公告)号：JP2006274245A
公开(公告)日：2006-10-12
申请号：JP2006049780
申请日：2006-02-27
申请人： Chisso Corp , Chisso Sekiyu Kagaku Kk , チッソ株式会社 , チッソ石油化学株式会社
发明人： YOSHIDA NAOYUKI , ISHIDA KAZUFUMI , SASAKI SHUJI , IKEDA TAKUO , HIRAKI JUN , AOYAMA SHIGEYUKI
IPC分类号： C08B5/14 , A61K8/73 , A61K31/717 , A61P17/00 , A61P43/00 , A61Q19/00
摘要： PROBLEM TO BE SOLVED: To provide a compound selected from sulfated cellulose and a salt thereof which can be used as an active ingredient for a cutaneous external preparation produced intending to prevent, ameliorate, improve or cure atopic cutaneous symptoms and is excellent in hydrolysis resistance, a dermatitis therapeutic agent and a cosmetic which uses the compound.
SOLUTION: The compound is selected from sulfated cellulose obtained from crystalline cellulose and a salt thereof and has solubility in pure water at 20°C of ≥3 g/L, and the dermatitis therapeutic agent and the cosmetic use the compound.
COPYRIGHT: (C)2007,JPO&INPIT

10. 发明专利

JP2008222604A Cosmetic extender and cosmetic composition containing the same 审中-公开
标题翻译：化妆品和化妆品组合物
公开(公告)号：JP2008222604A
公开(公告)日：2008-09-25
申请号：JP2007060845
申请日：2007-03-09
申请人： Chisso Corp , チッソ株式会社
发明人： YOSHIDA NAOYUKI , ISHIDA KAZUFUMI , YODA MASAKO
IPC分类号： A61K8/73 , A61Q1/02 , A61Q1/12 , A61Q90/00 , C08B5/14
CPC分类号： A61K8/731 , A61Q1/02 , A61Q1/04 , A61Q1/10 , A61Q1/12
摘要： PROBLEM TO BE SOLVED: To provide a cosmetic extender imparting protective and restorative effects to the skin, and formulated with cosmetics in various kinds of product forms such as a skincare cosmetic, a makeup cosmetic and a skin-cleansing agent; and to provide a cosmetic composition containing the extender.
SOLUTION: The cosmetic extender is a spherical sulfated cellulose obtained by esterifying a part of the hydroxy groups of a spherical cellulose with sulfuric acid, or a salt thereof.
COPYRIGHT: (C)2008,JPO&INPIT

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