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1. 发明专利

JPH0995407A GROWTH PROMOTING SUBSTANCE 失效
公开(公告)号：JPH0995407A
公开(公告)日：1997-04-08
申请号：JP25521195
申请日：1995-10-02
申请人： CHLORELLA IND
发明人： SUGANO TOSHIHIRO , SHINPO KUNIHIRO , TAMURA GORO , MASADA MASAHIRO
IPC分类号： A01N65/00 , C07G99/00 , C07G17/00
摘要： PROBLEM TO BE SOLVED: To obtain a growth promoting substance in the form of a simple substance from a unicellular green alga belonging to the genus Chlorella. SOLUTION: This growth promoting substance is a glycopeptide having an average molecular weight of

2. 发明专利

JPS55156584A TOBACCO FILTER 失效
公开(公告)号：JPS55156584A
公开(公告)日：1980-12-05
申请号：JP6344679
申请日：1979-05-23
申请人： CHLORELLA IND
发明人： YASUTOKU EIJI , SHINPO KUNIHIRO
IPC分类号： A24D3/08 , A24D3/06

3. 发明专利

JPH08188535A VIABLE BACTERIUM PREPARATION 失效
公开(公告)号：JPH08188535A
公开(公告)日：1996-07-23
申请号：JP58095
申请日：1995-01-06
申请人： CHLORELLA IND
发明人： MARUYAMA ISAO , ANDO YOTARO , SHINPO KUNIHIRO
IPC分类号： C12N1/20 , A61K9/20 , A61K35/74 , A61K35/745 , A61K35/747 , A61K36/05 , A61K47/06 , C12R1/01 , C12R1/46 , C12R1/89 , A61K35/80
摘要： PURPOSE: To obtain a viable bacterium preparation containing a viable bacteri um and chlorella powder as an excipient, useful for medicines, foods, etc., and capable of enhancing the survival rate of bacterial cells after prepared. CONSTITUTION: The viable bacterium preparation contains a viable bacterium, preferably lactobacillus, as a main ingredient and 60-90wt.% of chlorella powder as an excipient. The chlorella powder has following properties; a particle degree distribution: particle sizes of ; and an angle of repose: 42±5 degree. The addition of a conventional binder such as crystalline cellulose, calcium carboxymethylcellulose or α-starch to the chlorella in an amount of 3-20wt.% gives tablets high in hardness without killing the viable lactobacillus. If necessary, a lubricant, a perfume, a pigment, a pharmacodynamic ingredient, etc., may be added to prepare a formulation. The tabletting enables to prevent abrasion and defects generated on storage or carriage.

4. 发明专利

JPS6219528A CARCINOSTATIC AGENT 失效
公开(公告)号：JPS6219528A
公开(公告)日：1987-01-28
申请号：JP15651785
申请日：1985-07-16
申请人： CHLORELLA IND
发明人： SHINPO KUNIHIRO
IPC分类号： A61K36/05 , A61K36/02 , A61K38/00 , A61P35/00 , C07K14/405 , C12P1/00
摘要： NEW MATERIAL:A glycoprotein having carcinostatic activity and the following characteristics. Molecular weight, 45,000; protein constitution, composed of alpha-helix and random coil; sugar constitution, composed of beta-polysaccharide; circular dichroic spectrum, having positive peak at 275nm. USE:Carbinostatic agent. PREPARATION:Chlorella (microbial green algae) is extracted with hot water, concentrated at 50 deg.C under reduced pressure, diluted with distilled water, and passed through a semi-permeable membrane to obtain a polymeric fraction which cannot be passed through the membrane. The fraction is adjusted to 5.5pH and hydrolyzed by the addition of a liquid containing alpha-amylase. The hydrolyzed liquid is heated at 80 deg.C to deactivate alpha-amylase, the whole solution is dialyzed, the hydrolyzed sugar is discharged, and the residue is dried under reduced pressure. The dried component is subjected to gel-filtration to obtain the objective glycoprotein component.

5. 发明专利

JPS58128322A CARCINOSTATIC AGENT 失效
公开(公告)号：JPS58128322A
公开(公告)日：1983-07-30
申请号：JP1111682
申请日：1982-01-27
申请人： CHLORELLA IND
发明人： SHINPO KUNIHIRO , NISHITOI MUTSUMI
IPC分类号： A61K38/00 , A61K36/02 , A61K36/05 , A61P35/00
摘要： PURPOSE:A carcinostatic agent that contains glycoprotein separated from green microalgae as an active ingredient, thus acting on only tumor cells specifically and causing no effect on normal cells. CONSTITUTION:The objective glycoprotein is separated from green algae such as chlorella, scenedesmus or spirulina, having molecular weight of 121,000, isoelectric point of 8.6pH, glycoside/protein ratio, about 1:1, protein helix content, about 19%. Said glycoprotein shows antitumor activity both in vitro and in vivo, acts only on tumor cells, but does not on normal cells. Said carcinostatic agent is separated by extracting raw cake of chlorella which is cultivated using carbon dioxide, acetic acid, glucose or the like as a carbon source, treating the extract with a semipermeable membrane and fractionating the macromolecular fraction impermeable to the membrane by a variety of column chromatography.

6. 发明专利

JPS55144883A PREPARATION OF CHLORELLA 失效
公开(公告)号：JPS55144883A
公开(公告)日：1980-11-12
申请号：JP5389379
申请日：1979-05-01
申请人： CHLORELLA IND
发明人： SHINPO KUNIHIRO , ANTOKU EIJI , ITANAMI JIYUNZOU
IPC分类号： A23L35/00 , C12N1/12 , C12R1/89
摘要： PURPOSE:To prepare chlorella useful for preventing and treating hypoferric anemia, with a high content of effective bivalent iron in the total iron, by adding vitamin C to the chlorella culture immediately before the completion. CONSTITUTION:0.2wt% or more, preferably 0.2-0.5wt%, based on the algae of vitamin C is added to the chlorella culture immediately before the completion, i.e. 30min-2hr before the collection of the chlorella.

7. 发明专利

JPS5648854A SLIGHTLY SWEET WHEAT GLUTEN CONTAINING CHLORELLA 失效
公开(公告)号：JPS5648854A
公开(公告)日：1981-05-02
申请号：JP12506579
申请日：1979-09-28
申请人： CHLORELLA IND
发明人： SHINPO KUNIHIRO , ANTOKU EIJI
IPC分类号： A23G3/34 , A23G3/00
摘要： PURPOSE:A wheat gluten having a good taste, a low sweetness and a deodorizing action on the mouth, and comprising a raw material for the wheat gluten, a dried powder of an alga body of chlorella, a chlorella extract and soybean milk powder. CONSTITUTION:A slightly sweet wheat gluten containing chlorella prepared by mixing a raw material for the wheat gluten consisting of starch syrup and sugar essentially at a weight ratio between the wheat gluten and the starch syrup in the range of usually 5:5-7:3 with 0.2-0.5wt% a dried powder of an alga body of chlorella, 0.1-0.5wt% a chlorella extract and 2-5wt% soybean milk powder. The dried alga body powder of chlorella is preferably a fine powder of particle size 100- 150 mesh. The chlorella extract is prepared by freeze-drying or spray-drying an extract from an alga body of chlorella with hot water. The chlorella extract has taste adjusting and deodorizing actions and an action to removed the smell from the soybean milk powder. The soybean milk suppresses the increase of sweetness by the addition of the chlorella extract, and has an action to remove the grassy smell of the alga body of the chlorella.

8. 发明专利

JPS5618923A CARCINOSTATIC AND ITS PREPARATION 失效
公开(公告)号：JPS5618923A
公开(公告)日：1981-02-23
申请号：JP9435979
申请日：1979-07-25
申请人： CHLORELLA IND
发明人： KAMIYA NORIKIYO , OKUDA MASAO , SHINPO KUNIHIRO , ANTOKU EISHIKI
IPC分类号： A61K36/05 , A61K36/02 , A61P35/00
摘要： PURPOSE:The extract from chlorella with hot water is fractionated to give a carcinostatic. CONSTITUTION:Chlorella, unicellular green algae, is extracted with hot water and the extract is fractionated with column chromatograohy, e.g., using a Sephadex G-25 column, to separate a glycoprotein fraction containing a component rich in polysaccharides of more then 70,000 molecular weight and another component rich in proteins 3,000-9,000 molecular weight. Said fraction has life-prolonging effect on tumor P388 and can possibly used as a carcinostatic.

9. 发明专利

JPS55144872A CHLORELLA FOR ADDITIVE OF FOOD AND DRINK 失效
公开(公告)号：JPS55144872A
公开(公告)日：1980-11-12
申请号：JP5389479
申请日：1979-05-01
申请人： CHLORELLA IND
发明人： OCHIAI SATOSHI , MORI REIKO , SHINPO KUNIHIRO , ANTOKU EIJI
IPC分类号： A23L35/00 , A23L17/60
摘要： PURPOSE:Chlorella for additive of food and drink having improved dispersibility of chlorella alga free from its own smell, obtained by blending granular chlorella alga having given particle sizes with a fixed ratio of honey and powdered milk. CONSTITUTION:5-10wt% of a granular chlorella alga having particle sizes of 16- 60 mesh is blended with 30-50wt% of honey and 50-65wt% of powdered milk. A small amont of the essence of vanilla may be added if necessary. These ingredients are preferably blended for several minutes under heating.

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