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3. 发明专利

JP2009162234A Method and device for determining decompressed volume in pump cylinder 审中-公开
标题翻译：用于确定泵缸中分解体积的方法和装置
公开(公告)号：JP2009162234A
公开(公告)日：2009-07-23
申请号：JP2009004068
申请日：2009-01-09
申请人： Teledyne Isco Inc , テレダインイズコ、インク.Isco, Inc.
发明人： ALLINGTON ROBERT W , BLAKLEY SCOTT L , WALTERS HENRY L
IPC分类号： F04B49/06 , F04B1/02 , F04B9/04 , F04B11/00 , G01F11/04 , G01N30/32 , G01N30/36
CPC分类号： F04B1/02 , F04B11/0058 , F04B11/0083 , F04B49/065 , F04B2203/0209 , F04B2205/05 , F04B2205/09 , G01N30/36 , G01N2030/326
摘要： PROBLEM TO BE SOLVED: To provide a new arrangement for synchronizing a gradient generator by making a recompressed volume the same as a recompressed volume of a high pressure pump.
SOLUTION: A check valve is kept closed at an initial stage of a pumping stroke of a first piston by which fluid is compressed at a finite volumetric elastic module, and a second piston provides all flows at fixed rotation speeds. When pressure in a cylinder of the first piston reaches delivery pressure once, and a delivery check valve opens, a control system is changed over to a constant pressure control mode to maintain a flow rate at a fixed value. When the delivery check valve of the second piston is closed and pump control is returned to fixed rotation speed, constant pressure control is switched off again. Angular displacement making the control mode changeover effective is determined by monitoring delivery pressure, and storing a value of angular displacement at which the first-grade time differential of pressure is remarkably changed.
COPYRIGHT: (C)2009,JPO&INPIT
摘要翻译：要解决的问题：提供一种通过使再压缩体积与高压泵的再压缩体积相同的梯度发生器同步的新装置。解决方案：止回阀在第一活塞的泵送冲程的初始阶段保持关闭，第一活塞的流体在有限的体积弹性模块处被压缩，并且第二活塞以固定的转速提供所有流。当第一活塞的气缸中的压力达到一次输送压力并且释放止回阀打开时，将控制系统切换到恒定压力控制模式以将流量维持在固定值。当第二活塞的排放止回阀关闭并且泵控制返回到固定的转速时，再次关闭恒压控制。通过监视输送压力来确定控制模式切换有效的角位移，并且存储压差的一级时间差显着改变的角位移值。版权所有（C）2009，JPO＆INPIT

4. 发明专利

JP2004218635A High pressure reciprocating pump and its control 有权
标题翻译：高压重油泵及其控制
公开(公告)号：JP2004218635A
公开(公告)日：2004-08-05
申请号：JP2003391653
申请日：2003-11-21
申请人： Isco Inc , イズコ、インク.Isco, Inc.
发明人： ALLINGTON ROBERT W , BLAKLEY SCOTT L , WALTERS HENRY L
IPC分类号： F04B1/02 , F04B9/04 , F04B11/00 , F04B49/06 , G01N30/32 , G01N30/36
CPC分类号： F04B1/02 , F04B11/0058 , F04B11/0083 , F04B49/065 , F04B2203/0209 , F04B2205/05 , F04B2205/09 , G01N30/36 , G01N2030/326
摘要： PROBLEM TO BE SOLVED: To provide a high pressure reciprocating pump having an improved arrangement for synchronizing a gradient generator by making its recompression volume equal to that of a high pressure pump.
SOLUTION: The high pressure reciprocating pump is structured so that its check valve remains closed in the initial period of the pumping stroke of the first piston in which the fluid is compressed with a finite modulus of elasticity by volume and the second piston shares all flow at a fixed rotating speed. If then the pressure in the cylinder of the first piston once reaches the pressure of exhaustion and a discharge check valve is opened, the control system is changed over into the constant pressure control mode so as to maintain the rate of flow to the fixed value. When the discharge check valve of the second piston is closed and the pump control returns to the fixed rotating speed, the constant pressure control is switched off again. Determination of the angular displacement for making valid the changing-over of the control modes is executed by monitoring the discharge pressure and accommodating the value of angular displacement in which the first-grade time differential of the pressure changes remarkably.
COPYRIGHT: (C)2004,JPO&NCIPI
摘要翻译：要解决的问题：提供一种具有改进的布置的高压往复泵，其通过使其压缩体积等于高压泵的再压缩体积来同步梯度发生器。解决方案：高压往复泵的结构使得其止回阀在第一活塞的泵送冲程的初始阶段保持关闭，其中流体以有限的弹性体积被压缩而被压缩，第二活塞分配全部以固定的转速流动。然后，如果第一活塞的气缸中的压力一旦达到排气压力并且排气止回阀打开，则将控制系统切换到恒压控制模式，以将流量的速率保持在固定值。当第二活塞的排放止回阀关闭并且泵控制返回到固定转速时，恒压控制再次被切断。通过监测排出压力并适应压力的一级时间差显着变化的角位移值，来确定用于使控制模式转换有效的角位移。版权所有（C）2004，JPO＆NCIPI

5. 发明专利

JP2009121483A Method and device for accelerating mixing of solvent and solute 审中-公开
标题翻译：用于加速溶剂和溶剂混合的方法和装置
公开(公告)号：JP2009121483A
公开(公告)日：2009-06-04
申请号：JP2009004069
申请日：2009-01-09
申请人： Teledyne Isco Inc , テレダインイズコ、インク.Isco, Inc.
发明人： ALLINGTON ROBERT W , BLAKLEY SCOTT L , WALTERS HENRY L
IPC分类号： F04B13/00 , B01F11/00 , F04B1/02 , F04B9/04 , F04B11/00 , F04B49/06 , G01N30/32 , G01N30/36
CPC分类号： F04B1/02 , F04B11/0058 , F04B11/0083 , F04B49/065 , F04B2203/0209 , F04B2205/05 , F04B2205/09 , G01N30/36 , G01N2030/326
摘要： PROBLEM TO BE SOLVED: To provide a new arrangement for synchronizing gradient generator by equalizing re-compression volume to re-compression volume of a high pressure pump. SOLUTION: During the initial portion of the pumping stroke of a first piston in which fluid is being compressed due to its finite bulk modulus of elasticity its check valve remains closed, a second piston provides all the flow required at a fixed rotational speed. Then, once the pressure inside the first piston's cylinder has reached that of the discharge and its discharge check valve opens, the control system switches to a constant-pressure control mode, thereby maintaining the flow rate at a fixed value. Constant-pressure control is again switched off when the second piston's discharge check valve closes, and pump control returns to fixed rotational speed. Determining the angular displacement at which to effect these control-mode switches is carried out by monitoring the discharge pressure and storing the values of the angular displacement at which the first temporal derivative of pressure changes rapidly. COPYRIGHT: (C)2009,JPO&INPIT
摘要翻译：要解决的问题：提供一种通过使再压缩体积与高压泵的再压缩体积相等来同步梯度发生器的新装置。解决方案：在第一活塞的泵送冲程的初始部分期间，由于其有限的体积弹性模量，流体被压缩，其止回阀保持关闭，第二活塞提供固定转速所需的所有流量。然后，一旦第一活塞气缸内的压力达到排放压力，其排气止回阀打开，则控制系统切换到恒压控制模式，从而将流量维持在固定值。当第二活塞的排放止回阀关闭时，恒压控制再次关闭，并且泵控制返回到固定的转速。确定实现这些控制模式开关的角位移通过监视排出压力并存储压力的第一时间导数快速变化的角位移的值来进行。版权所有（C）2009，JPO＆INPIT

6. 发明专利

JP2004309487A Improved method and device for enhancing ratio of signal to noise in chromatography 审中-公开
公开(公告)号：JP2004309487A
公开(公告)日：2004-11-04
申请号：JP2004115949
申请日：2004-04-09
申请人： Isco Inc , イズコ、インク.Isco, Inc.
发明人： ALLINGTON ROBERT W
IPC分类号： G01N27/447 , G01N30/02 , G01N30/26 , G01N30/30 , G01N30/32 , G01N30/62 , G01N30/74 , G01N30/78 , G01N30/86
CPC分类号： G01N30/8603 , G01N27/44717 , G01N27/44721 , G01N30/78 , G01N2030/626 , Y10T436/25 , G01N2030/324
摘要： PROBLEM TO BE SOLVED: To enhance a signal-to-noise ratio in chromatography. SOLUTION: (1) One embodiment: A flow of a solution is stopped together with a solvent spike directed to a specified photocell sensor. Then, a single continuous scan or a plurality of scans is carried out in a section of the stationary solution to be integrated, totalized or correlated statistically. (2) Another embodiment: The solvent spike is detected to be tracked. The set of photocell sensors is selected in a time increment to bring a leading photocell to a position of the solvent spike. The set of photocell sensors is scanned repeatedly. Important information contained in a signal integrated, totalized or correlated is compared with noise information to increase a chromatographic signal. An effective optical path length is increased without including a moving component, or without loosing resolution notably. COPYRIGHT: (C)2005,JPO&NCIPI

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