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71. 发明专利

JP2014141496A Exercise function-improving agent 审中-公开
标题翻译：锻炼功能改善剂
公开(公告)号：JP2014141496A
公开(公告)日：2014-08-07
申请号：JP2014040738
申请日：2014-03-03
申请人： Kao Corp , 花王株式会社
发明人： OTA NOBUYASU , HARAMIZU SATOSHI , MURASE TAKATOSHI
IPC分类号： A61K31/688 , A23K1/16 , A23L1/30 , A61K35/20 , A61P3/02 , A61P21/00
摘要： PROBLEM TO BE SOLVED: To provide an exercise function-improving agent, an endurance-improving agent, a fatigue-resisting agent, a muscular strength-improving agent, a glycogen reserve-promoting agent and a muscular pumping ability-improving agent which are safe, easily obtained and excellent in processability.SOLUTION: Disclosed is an oral solid preparation or a nutritional support composition which contains 2-50 mass% of a fat globule membrane component, preferably 1-50 mass% of sphingomyelin in terms of dry substance. The function-improving agent is used as exercise function-improving agent, an endurance-improving agent, a fatigue-resisting agent, a muscular strength-improving agent, a glycogen reserve-promoting agent and a muscular pumping ability-improving agent.
摘要翻译：要解决的问题：提供安全的运动功能改善剂，耐久性改善剂，耐疲劳剂，肌肉强度改善剂，糖原储备促进剂和肌肉抽动能力改善剂易于获得，加工性优异。解决方案：公开了含有2-50质量％的脂肪球膜成分，优选为干物质为1〜50质量％的鞘磷脂的口服固体制剂或营养支持组合物。功能改善剂用作运动功能改善剂，耐久性改善剂，耐疲劳剂，肌肉强度改善剂，糖原储备促进剂和肌肉抽动能力改善剂。

72. 发明专利

JP2014133711A Cgi-58 expression promoter 有权
标题翻译： CGI-58表达促销者
公开(公告)号：JP2014133711A
公开(公告)日：2014-07-24
申请号：JP2013002066
申请日：2013-01-09
申请人： Kao Corp , 花王株式会社
发明人： MORI SHINOBU , KIUCHI SATOMI , MURASE TAKATOSHI , HASHIZUME KOJIRO , KUSUOKU HIROSHI
IPC分类号： A61K8/97 , A61K36/18 , A61K36/24 , A61K36/53 , A61K36/75 , A61P17/00 , A61P17/14 , A61P43/00 , A61Q7/00 , A61Q19/00 , A61Q19/10
摘要： PROBLEM TO BE SOLVED: To provide CGI-58 expression promoters that promote CGI-58 expression.SOLUTION: A CGI-58 expression promoter includes at least one selected from the group consisting of Puer tea extracts, Apocynum venetum extracts, Psidium guajava extracts, Citrus aurantium extracts, Juniperus communis extracts, and Scutellaria baicalensis extracts, as an active ingredient.
摘要翻译：要解决的问题：提供促进CGI-58表达的CGI-58表达启动子。解决方案：CGI-58表达启动子包括选自由普洱茶提取物，苹果叶提取物，爪哇草提取物，柑橘 ium提取物，桧属提取物，黄芩提取物作为活性成分。

73. 发明专利

JP2013035763A Fat accumulation suppressor 有权
标题翻译： FAT累积抑制剂
公开(公告)号：JP2013035763A
公开(公告)日：2013-02-21
申请号：JP2011171658
申请日：2011-08-05
申请人： Kao Corp , 花王株式会社
发明人： URANO SATOMI , MORI SHINOBU , MURASE TAKATOSHI
IPC分类号： A61K38/00 , A23L1/305 , A61K47/34 , A61K47/48 , A61P3/04 , A61P3/06 , A61P3/10 , A61P9/00 , A61P9/12 , A61P43/00
摘要： PROBLEM TO BE SOLVED: To provide a material capable of suppressing fat cell differentiation and maturation or fat accumulation and effective for prevention and amelioration of symptoms due to adiposity.SOLUTION: A fat cell differentiation and maturation and/or fat accumulation suppressor includes, as an effective ingredient, a C-terminus amidated polypeptide comprising an amino acid sequence wherein 0-3 amino acids are connected to the N-terminus side of an amino acid sequence represented by a sequence number 1.
摘要翻译：要解决的问题：提供能够抑制脂肪细胞分化和成熟或脂肪蓄积并有效预防和改善由于肥胖引起的症状的材料。解决方案：脂肪细胞分化和成熟和/或脂肪蓄积抑制剂包括作为有效成分的C末端酰胺化多肽，其包含氨基酸序列，其中0-3个氨基酸连接到N末端侧由序列号1表示的氨基酸序列。（C）2013，JPO＆INPIT

74. 发明专利

JP2011157330A Motor function improving agent 有权
标题翻译：电机功能改进剂
公开(公告)号：JP2011157330A
公开(公告)日：2011-08-18
申请号：JP2010022223
申请日：2010-02-03
申请人： Kao Corp , 花王株式会社
发明人： OTA NOBUYASU , HARAMIZU SATOSHI , HASHIZUME KOJIRO , MURASE TAKATOSHI
IPC分类号： A61K31/688 , A61P3/02 , A61P21/00 , A61P43/00
摘要： PROBLEM TO BE SOLVED: To provide a stamina improving agent, a muscle strength improving agent, a muscular depression inhibiting agent and an anti-fatigue agent having high safety, easy availability and excellent processability.
SOLUTION: There are provided the stamina improving agent, muscle strength improving agent, muscular depression inhibiting agent and anti-fatigue agent containing sphingomyelin as an active component.
COPYRIGHT: (C)2011,JPO&INPIT
摘要翻译：待解决的问题：提供一种耐力改善剂，肌肉力量改善剂，肌抑制抑制剂和抗疲劳剂，其安全性高，易于获得和优异的加工性。解决方案：提供耐力改善剂，肌肉力量改善剂，肌抑制抑制剂和含有鞘磷脂作为活性成分的抗疲劳剂。版权所有（C）2011，JPO＆INPIT

75. 发明专利

JP2011157329A Mitochondria function-improving agent 有权
标题翻译： MITOCHONDRIA功能改进剂
公开(公告)号：JP2011157329A
公开(公告)日：2011-08-18
申请号：JP2010022222
申请日：2010-02-03
申请人： Kao Corp , 花王株式会社
发明人： HARAMIZU SATOSHI , OTA NOBUYASU , MURASE TAKATOSHI
IPC分类号： A61K35/20 , A23K1/16 , A23L1/30 , A61P3/00 , A61P3/06 , A61P43/00
CPC分类号： A23L2/52 , A23K20/158 , A23L33/10 , A23L33/115 , A61K35/20
摘要： PROBLEM TO BE SOLVED: To provide a mitochondria function-improving agent, energy consumption-promoting agent or fat combustion-promoting agent useful as a medicine, a food or the like.
SOLUTION: There is provided the mitochondria function-improving agent, energy consumption-promoting agent or fat combustion-promoting agent containing a fat globule membrane ingredient as an active ingredient.
COPYRIGHT: (C)2011,JPO&INPIT
摘要翻译：要解决的问题：提供可用作药物的线粒体功能改善剂，能量消耗促进剂或脂肪燃烧促进剂，食品等。解决方案：提供含有脂肪球膜成分作为活性成分的线粒体功能改善剂，能量消耗促进剂或脂肪燃烧促进剂。版权所有（C）2011，JPO＆INPIT

76. 发明专利

JP2010070540A Dgat inhibitor 审中-公开
标题翻译： DGAT抑制剂
公开(公告)号：JP2010070540A
公开(公告)日：2010-04-02
申请号：JP2009183642
申请日：2009-08-06
申请人： Kao Corp , 花王株式会社
发明人： KONDO HIDEHIKO , HASHIZUME KOJIRO , MURASE TAKATOSHI
IPC分类号： A61K31/7024 , A23L1/30 , A23L2/52 , A61P3/04 , A61P3/06 , A61P3/10 , A61P5/50 , A61P43/00 , C12N9/99
摘要： PROBLEM TO BE SOLVED: To provide a DGAT inhibitor effective for prevention or amelioration of hyperlipidemia, obesity, insulin resistance and diabetes.
SOLUTION: The diacylglycerol acyltransferase (DGAT) inhibitor comprises ellagitannin or a derivative thereof as an effective ingredient.
COPYRIGHT: (C)2010,JPO&INPIT
摘要翻译：要解决的问题：提供有效预防或改善高脂血症，肥胖，胰岛素抵抗和糖尿病的DGAT抑制剂。解决方案：二酰基甘油酰基转移酶（DGAT）抑制剂包括鞣花素或其衍生物作为有效成分。版权所有（C）2010，JPO＆INPIT

77. 发明专利

JP2010037255A Agent for preventing or ameliorating visual dysfunction 审中-公开
标题翻译：防止或修复视觉障碍的代理
公开(公告)号：JP2010037255A
公开(公告)日：2010-02-18
申请号：JP2008200849
申请日：2008-08-04
申请人： Kao Corp , 花王株式会社
发明人： TAKAHASHI YOSHISHIRO , KONDO HIDEHIKO , HASHIZUME KOJIRO , MURASE TAKATOSHI
IPC分类号： A61K36/18 , A23L1/06 , A23L1/30 , A23L2/52 , A61K36/48 , A61K36/53 , A61P27/00 , A61P43/00 , C12N15/09
摘要： PROBLEM TO BE SOLVED: To provide an agent for the prevention and/or amelioration of visual dysfunction, having high safety and useful as a drug, quasi-drug, food, etc. SOLUTION: The agent for the prevention and/or amelioration of visual dysfunction contains one or more kinds of plants selected from Caesalpinia sappan, Zingiber officinale and Perilla frutescens or its extract as an active component. COPYRIGHT: (C)2010,JPO&INPIT
摘要翻译：要解决的问题：提供用于预防和/或改善视力功能障碍的药剂，具有高度安全性并且作为药物，准药物，食品等有用。解决方案：用于预防的药剂和/或视力功能障碍的改善包含选自凯撒ia an，姜黄和紫苏或其提取物作为活性成分的一种或多种植物。版权所有（C）2010，JPO＆INPIT

78. 发明专利

JP2009242382A Ppar activator 有权
标题翻译： PPAR激活剂
公开(公告)号：JP2009242382A
公开(公告)日：2009-10-22
申请号：JP2009052213
申请日：2009-03-05
申请人： Kao Corp , 花王株式会社
发明人： MISAWA KOICHI , TAKIGAWA HIROBUMI , MURASE TAKATOSHI
IPC分类号： A61K36/48 , A61K36/00 , A61P1/14 , A61P1/16 , A61P3/04 , A61P3/06 , A61P3/10 , A61P5/50 , A61P43/00
摘要： PROBLEM TO BE SOLVED: To provide a drug, a quasi-drug and a food safely takable over a long time, having excellent PPAR activation action and exhibiting effects such as activation of fatty acid metabolism, promotion of body fat burning, suppression of obesity, suppression of fatty liver, improvement in stamina, prevention-amelioration of diabetes and prevention-amelioration of insulin resistance. SOLUTION: The PPAR (peroxisome proliferator-activated receptor) activator contains soy sauce cake or its extract as an active component. COPYRIGHT: (C)2010,JPO&INPIT
摘要翻译：要解决的问题：为了提供长时间安全可食用的药物，准药物和食品，具有优异的PPAR活化作用并表现出诸如脂肪酸代谢活化，促进身体脂肪燃烧，抑制肥胖，抑制脂肪肝，改善耐力，预防糖尿病改善和预防胰岛素抵抗的改善。解决方案：PPAR（过氧化物酶体增殖物激活受体）激活剂含有酱油饼或其提取物作为活性成分。版权所有（C）2010，JPO＆INPIT

79. 发明专利

JP2009226069A METHOD OF CONTROLLING TGF β SIGNALING PATH 审中-公开
标题翻译：控制TGFβ信号途径的方法
公开(公告)号：JP2009226069A
公开(公告)日：2009-10-08
申请号：JP2008076368
申请日：2008-03-24
申请人： Kao Corp , 花王株式会社
发明人： AOKI MASAFUMI , MURASE TAKATOSHI
IPC分类号： A61F7/00
摘要： PROBLEM TO BE SOLVED: To provide a method of controlling a TGF β signal without the need of treatment and drug administration by a doctor.
SOLUTION: The method of controlling a TGF β signaling path is characterized in that thermal stimulation is given to an affected area or a whole body. The above method inhibits the expression of Smad3.
COPYRIGHT: (C)2010,JPO&INPIT

80. 发明专利

JP2008255048A Ampk-activating agent 审中-公开
标题翻译： AMPK活化剂
公开(公告)号：JP2008255048A
公开(公告)日：2008-10-23
申请号：JP2007098463
申请日：2007-04-04
申请人： Kao Corp , 花王株式会社
发明人： MURASE TAKATOSHI
IPC分类号： A61K36/18 , A61P3/04 , A61P3/06 , A61P3/10 , A61P5/50 , A61P9/10 , A61P43/00
摘要： PROBLEM TO BE SOLVED: To provide an easily available AMPK (AMP-activated protein kinase)-activating agent being highly safe because of rich eating experience, having excellent processability, and realistically utilizable to human beings. SOLUTION: The AMPK-activating agent contains a leaf of a grape or an extract thereof as an active ingredient. The agent for preventing and/or ameliorating fatness contains the leaf of the grape or the extract thereof as an active ingredient. COPYRIGHT: (C)2009,JPO&INPIT

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