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61. 发明专利

JP2001237455A InAlGaN EMITTING LIGHT IN SHORT-WAVELENGTH REGION OF ULTRAVIOLET REGION, ITS MANUFACTURING METHOD AS WELL AS ULTRAVIOLET LIGHT-EMITTING ELEMENT USING THE SAME 失效
公开(公告)号：JP2001237455A
公开(公告)日：2001-08-31
申请号：JP2000045318
申请日：2000-02-23
申请人： RIKAGAKU KENKYUSHO , HIRAYAMA HIDEKI
发明人： HIRAYAMA HIDEKI , AOYANAGI KATSUNOBU
IPC分类号： C01G15/00 , C23C16/34 , H01L33/06 , H01L33/32 , H01L33/34 , H01L33/00
摘要： PROBLEM TO BE SOLVED: To emit light at room temperature and with high efficiency in a short-wavelength region as an ultraviolet region at a wavelength of 360 nm or shorter. SOLUTION: The composition ratio of In is set at 2 to 20%. The composition ratio of Al is set at 10 to 90%, and the total of the composition ratios of In, Al and Ga is set so that it becomes 100%.

62. 发明专利

JP2001209928A TEXTURING METHOD AND DEVICE 失效
公开(公告)号：JP2001209928A
公开(公告)日：2001-08-03
申请号：JP2000016622
申请日：2000-01-26
申请人： RIKAGAKU KENKYUSHO , SHOWA DENKO KK
发明人： OMORI HITOSHI , HAYASHI IMIN , ITO NOBUHIDE , MORIYA NORIO
IPC分类号： G11B5/84
摘要： PROBLEM TO BE SOLVED: To provide a texturing method and a device which can be installed in a clean room together with preceding and following process equipment with very little occurrence of the soil, and whose processing efficiency is high com pared with loose abrasive grain, and can perform the stable texturing processing. SOLUTION: The texturing is applied to a substrate surface by forcing the cylindrical surface of a tool on the substrate surface, and making the tool and the substrate move relatively along the substrate surface, rotationally driving a disk-like substrate 1 centering on the axial center, and rotationally driving the cylinder-like tool 12 centering on the axial center parallel to the substrate surface, and cleaning the cylindrical surface of the tool and the substrate surface. The cylinder-like tool 12 is used as an anode through a power feeding body 14, uses as a cathode the circular electrode 16 opposed to the cylindrical surface of the cylinder-like tool, supplies conductive working liquid 7 between the cylinder-like tool and the circular electrode, applies the electrolysis dressing, and cleans the cylindrical surface of the tool.

63. 发明专利

JP2001204499A METHOD FOR DETECTING CELL IN HISTOGENESIS STEP IN REAL TIME 失效
公开(公告)号：JP2001204499A
公开(公告)日：2001-07-31
申请号：JP2000011623
申请日：2000-01-20
申请人： RIKAGAKU KENKYUSHO
发明人： MIYATA TAKAKI
IPC分类号： G01N33/48 , C12N5/10 , C12N15/09 , C12Q1/02 , C12Q3/00 , G01N33/483
摘要： PROBLEM TO BE SOLVED: To provide a culturing method and a method for detecting a cell by which the histogenesis process can be observed in real time. SOLUTION: This method for detecting the cell in the histogenesis process is characterized in that a fluorochrome is detected while culturing a section obtained by linking fluorochrome protein gene to a tissue-specifically expressing gene, transducing the obtained gene complex to an animal to provide a transgenic animal, and forming the objective tissue section from the transgenic animal.

64. 发明专利

JP2001201597A COHERENT LIGHT SOURCE DEVICE 失效
公开(公告)号：JP2001201597A
公开(公告)日：2001-07-27
申请号：JP2000009363
申请日：2000-01-18
申请人： RIKAGAKU KENKYUSHO
发明人： KUMAGAI HIROSHI , MIDORIKAWA KATSUMI
IPC分类号： G21K1/00
摘要： PROBLEM TO BE SOLVED: To provide a coherent light source device used for the movement control of atomic beams of various atoms or the isotope control of various elements. SOLUTION: This device comprises a first coherent light source for generating a first coherent light having a prescribed wavelength λ1, a second coherent light source for generating a second coherent light having a prescribed wavelength λ2, and a resonator for receiving the first coherent light generated by the first coherent light source and the second coherent light generated by the second coherent light source and resonating the first and second coherent lights, respectively, to generate and emit a coherent light having a wavelength λx. The equation of 1/λ1+1/λ2=1/λx is established between the wavelength λ1 and the wavelength λ2, the first coherent light satisfies conditions of the wavelength λ1, single vertical mode, constant frequency, single horizontal mode and high output, and the second coherent light satisfies conditions of the wavelength λ2, single vertical mode, variable frequency, single horizontal mode, and high output.

65. 发明专利

JP2001201451A ACM SENSOR AND MANUFACTURING METHOD THEREFOR 失效
公开(公告)号：JP2001201451A
公开(公告)日：2001-07-27
申请号：JP2000011147
申请日：2000-01-20
申请人： RIKAGAKU KENKYUSHO , NEXSYS CORP
发明人： OMORI HITOSHI , YAMAGATA YUTAKA , MORIYASU KIYOSHI , UEHARA YOSHIHIRO , TSUJIKAWA SHIGEO , SHINOHARA TADASHI , ASAMI MUNEAKI
IPC分类号： G01N17/04
摘要： PROBLEM TO BE SOLVED: To provide an ACM sensor whose service life is long, which is of high sensitivity, in which an irregularity in an output is small, in which a yield in its manufacture is high and whose cost can be lowered, and to provide its manufacturing method. SOLUTION: The manufacturing method is composed of a pretreatment process 30, in which the anchor force on the surface of a substrate composed of a conductive material is enhances. The manufacturing method is composed of an insulating-film thermal spray process 32, in which an insulating material is thermally sprayed to the surface of the substrate so as to form an insulating film. The manufacturing method is composed of a conductive-film thermal spray process 34, in which the conductive material different from that of the substrate is thermally sprayed to the surface of the insulating film so as to form a conductive film. The manufacturing method is composed of a planarizing process 36, in which the surface of the conductive film is ground to be smooth. The manufacturing method is composed of a slit-working process 38 in which the conductive film, and the insulating film are ground and removed in a slit shape. In the planarizing process and/or the silt-working process, an ELID grinding method in which a grinding operation is performed, while a conductive whetstone is dressed electrolytically is used.

66. 发明专利

JP2001161366A POLYPEPTIDE COMPLEX HAVING DNA RECOMBINATIONAL ACTIVITY 失效
公开(公告)号：JP2001161366A
公开(公告)日：2001-06-19
申请号：JP34646799
申请日：1999-12-06
申请人： JAPAN SCIENCE & TECH CORP , RIKAGAKU KENKYUSHO
发明人： KURUMIZAKA HITOSHI , YOKOYAMA SHIGEYUKI , SHIBATA TAKEHIKO
IPC分类号： C12N15/09 , C12N1/15 , C12N1/19 , C12N1/21 , C12N5/10 , C12N9/00
摘要： PROBLEM TO BE SOLVED: To provide a substance having high homologous conjugation activity, to provide a method for producing the substance, to provide a vector to be used for the above method, and to provide a transformant having high homologous conjugation activity. SOLUTION: The subject complex is produced by expressing a DNA encoding Xrcc3 and Rad51C or DNA encoding Rad51B and Rad51C and then collecting the resultant complex of Xrcc3 and Rad51C or the resultant complex of Rad51B and Rad51C. The 2nd objective vector containing the DNA encoding Xrcc3 and Rad51C or DNA encoding Rad51B and Rad51C is constructed. The 3rd objective transformant is obtained by enhancing the expression of the DNA encoding Xrcc3 and Rad51C or DNA encoding Rad51B and Rad51C.

67. 发明专利

JP2001131074A MEDICAMENT CONTAINING SIALIC ACID DERIVATIVE AS ACTIVE COMPONENT 失效
公开(公告)号：JP2001131074A
公开(公告)日：2001-05-15
申请号：JP2000249232
申请日：2000-08-21
申请人： RIKAGAKU KENKYUSHO
发明人： KANIE OSAMU , CHI-WAY WONG , SUZUKI YASUO
IPC分类号： C07H15/04 , A61K31/7028 , A61K31/7034 , A61K31/7042 , A61K31/7048 , A61P31/12 , A61P31/16 , A61P43/00 , C07H15/203 , C07H17/075
摘要： PROBLEM TO BE SOLVED: To provide new medicaments comprising a sialic acid derivative, especially a low-molecular sialic acid derivative, and more concretely to provide a prophylactic and/or therapeutic agent for viral disease such as influenza virus infection disease. SOLUTION: The medicaments comprise a compound represented by formula I wherein R1 is a 1-6C alkyl group; R2 is a (substituted) phenyl group, a 1-20C alkyl group, a 1-20C alkenyl group or (CH2)k-[NH-(CH2)m-NH]n-Y (wherein Y is phoshatidyl ethanolamine residue, polyglutamic acid residue or the like; k and m are each an integer of 2 to 10); R3 is H or a (substituted) hydroxy group; R4 is H, a halogen, azido group, a (substituted) amino group or a (substituted) hydroxy group; and R5 to R8 are each a (substituted) hydroxy group} or its pharmacologically permissive salt as an active component.

68. 发明专利

JP2001097887A METHOD FOR SCREENING MEDICINE FOR CROHN'S DISEASE 失效
公开(公告)号：JP2001097887A
公开(公告)日：2001-04-10
申请号：JP27775999
申请日：1999-09-30
申请人： RIKAGAKU KENKYUSHO
发明人： NATORI SHUNJI
IPC分类号： A61K45/00 , A61P1/00 , C12Q1/02 , G01N33/15 , G01N33/50
摘要： PROBLEM TO BE SOLVED: To identify a material producing TNF-α by activating a human intestinal macrophage. SOLUTION: This method for screening a medicine for therapy and/or prophylaxis of Crohn's disease comprises culturing the human intestinal macrophage in the presence of a test medicine and Sarcophaga lectin, and monitoring the inhibition by the test medicine in the TNF production by the macrophage.

69. 发明专利

JP2001072694A FIXED COMPLEX 失效
公开(公告)号：JP2001072694A
公开(公告)日：2001-03-21
申请号：JP25385199
申请日：1999-09-08
申请人： RIKAGAKU KENKYUSHO
发明人： WAKATSUKI YASUO , SUZUKI NORIYUKI , THOMAS FUUN , ICHIKAWA MASARU , FUKUOKA ATSUSHI
IPC分类号： C07F17/00 , C07F7/00 , C07F19/00 , C08F4/656 , C08F4/659 , C08F4/6592
摘要： PROBLEM TO BE SOLVED: To obtain a new compound higher in olefin polymerization activity than impregnation-carried complexes by fixing a group 4 metallocene- methylaluminoxane-based catalyst via covalent bond on the surface of a solid carrier. SOLUTION: This new compound is represented by formula I (the three- dimensional structure is one of two kinds of optically active modifications; R1 and R2 are each H or methyl; M1 is a silicon or germanium atom; M2 is a zirconium titanium or hafnium atom; n is 1-4; m is 2-12; Y is a silicon atom covalent-bound to hydroxy group on the surface of a solid carrier), e.g. a compound of formula II. The compound of formula I is obtained, for example, by reacting a compound of formula III (the three-dimensional structure is one of two kinds of optically active modifications; R11 and R12 are each H or methyl; M11 is a silicon or germanium atom; M12 is a zirconium, titanium or hafnium; p is 1-4) with a solid carrier with the hydroxy group alkenylsilylated which is prepared by reaction of a cholorodimethylalkenylsilane with the hydroxy group on the surface of the solid carrier.

70. 发明专利

JP2001064313A CATALYST COMPOSITION 失效
公开(公告)号：JP2001064313A
公开(公告)日：2001-03-13
申请号：JP24173799
申请日：1999-08-27
申请人： RIKAGAKU KENKYUSHO
发明人： AIDA SHOJIRO , KOU SHIYOUMIN , WAKATSUKI YASUO
IPC分类号： C08F4/52 , C08F4/54 , C08F236/10
摘要： PROBLEM TO BE SOLVED: To obtain a catalyst composition for copolymerization of a conjugated diene with an aromatic vinyl compound, a co-catalyst included in the catalyst composition and a novel copolymer produced by using the catalyst composition. SOLUTION: The catalyst composition is the one for copolymerization of a conjugated diene with an aromatic vinyl compound and includes (A) a methallocene complex of a rare earth metal compound (for example, a samarium complex, or the like) and (B) an ionic compound comprising a non-coordinating anion and a cation [triphenyl carbonium tetrakis (pentafluorophenyl) borate, or the like] and/or aluminoxane.

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