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31. 发明专利

JP2013079968A Sample analysis method 有权
标题翻译：样本分析方法
公开(公告)号：JP2013079968A
公开(公告)日：2013-05-02
申请号：JP2012263387
申请日：2012-11-30
申请人： Sysmex Corp , シスメックス株式会社
发明人： NARUKAWA TAKANARI , TSUJI TOMOHISA , MORIYAMA KEIKO , ITOSE YUUJI , KOKUNI SHINICHIRO , YOSHIDA AYUMI , SUZUKI SAORI , MIZUKAMI TOSHIHIRO
IPC分类号： G01N33/49 , G01N15/14
CPC分类号： G01N33/582 , G01N15/1459 , G01N21/6428 , G01N2015/1006 , G01N2015/1402
摘要： PROBLEM TO BE SOLVED: To provide a sample measuring method capable of more accurately discriminating nucleated erythrocytes and basophils from the other leucocytes in a sample to count them.SOLUTION: A sample analysis method comprises: hemolyzing erythrocytes in a sample by a first reagent containing cationic surfactant, nonionic surfactant, and aromatic carboxylic acid to do damage to the extent of allowing fluorescent dye to pass through the cell membranes of corpuscles, and dyeing the damaged corpuscles by a second reagent containing fluorescent dye capable of dyeing nucleic acids; irradiating the dyed corpuscles with light to acquire scattered light information and fluorescent information; and classifying and counting basophils and nucleated erythrocytes in the sample on the basis of the scattered light information and the fluorescent information.
摘要翻译：要解决的问题：提供一种能够更准确地区分来自样品中的其它白细胞的有核红细胞和嗜碱性粒细胞以进行计数的样品测量方法。解决方案：样品分析方法包括：通过含有阳离子表面活性剂，非离子表面活性剂和芳族羧酸的第一试剂使样品中的红细胞溶血，使荧光染料通过细胞膜的程度受损，并通过含有能够染色核酸的荧光染料的第二试剂染色损伤的小体; 用光照射染色小体以获取散射光信息和荧光信息; 并根据散射光信息和荧光信息对样品中的嗜碱性粒细胞和有核红细胞进行分类和计数。版权所有（C）2013，JPO＆INPIT

32. 发明专利

JP2013036756A Specimen analyzer 有权
标题翻译：样品分析仪
公开(公告)号：JP2013036756A
公开(公告)日：2013-02-21
申请号：JP2011170498
申请日：2011-08-03
申请人： Sysmex Corp , シスメックス株式会社
发明人： WAKAMIYA YUJI , NISHIDA TOMOYUKI
IPC分类号： G01N35/00 , G01N35/04
CPC分类号： G01N35/00584 , G01N35/00603 , G01N35/0092 , G01N35/025
摘要： PROBLEM TO BE SOLVED: To quickly start measurement of a new specimen even when measurement operation of many cuvettes is interrupted due to operation abnormality.SOLUTION: A measurement part 2 includes a rotatable reaction table 200. When receiving a measurement start instruction, a control part 4 detects residual cuvettes in the reaction table 200. When there are residual cuvettes, the control part 4 determines whether or not interference is generated among these residual cuvettes, and when no interference is generated, sets a new specimen on the reaction table 200, rotates the reaction table 200 and successively performs treatment. When the residual cuvettes are transferred up to a transfer end position C56 interlocking with the treatment, suction removal of residual liquid and disposal of the residual liquid to a disposal hole W are performed by a drain part 282.
摘要翻译：要解决的问题：即使由于操作异常而使多个比色皿的测量操作中断，也能够快速开始新试样的测定。测量部分2包括可旋转的反应台200.当接收到测量开始指令时，控制部分4检测反应台200中的残余反应杯。当存在残留的比色皿时，控制部分4确定是否在这些残留反应杯之间产生干扰，当不产生干扰时，在反应台200上设置新试样，使反应台200旋转并依次进行处理。当残留的比色皿被传送到与处理联动的传送结束位置C56时，通过排出部282执行残留液体的抽吸去除和残留液体的处理到处置孔W。版权所有（C） 2013年，JPO＆INPIT

33. 发明专利

JP2013024881A Analyzer, analysis method, and computer program 有权
标题翻译：分析仪，分析方法和计算机程序
公开(公告)号：JP2013024881A
公开(公告)日：2013-02-04
申请号：JP2012162133
申请日：2012-07-20
申请人： Sysmex Corp , シスメックス株式会社
发明人： JAMES AUSDENMOORE , PETER OSELLA , RALPH TAYLOR
IPC分类号： G01N35/00
CPC分类号： G01N35/00663 , G01N35/00603 , G01N35/00623
摘要： PROBLEM TO BE SOLVED: To provide an analysis system capable of securing that samples are analyzed through correct procedures, when analyzing the samples.SOLUTION: An analyzer 105 for analyzing samples includes measurement hardware 128 for measuring the samples, and a control part 127. The control part is configured to urge an execution of an accuracy management measurement on a first accuracy management sample stored in a first sample vial 130; receive a result of the accuracy management measurement of the first sample vial 130 that has been executed in the measurement hardware 128; and when the result of the accuracy management measurement is out of a predetermined range and the number of times when the result of the accuracy management measurement is out of the predetermined range is less than a predetermined number, urge the execution of the accuracy management measurement on the first sample vial 130 again.
摘要翻译：要解决的问题：在分析样品时，提供一种能够确保通过正确程序分析样品的分析系统。解决方案：用于分析样本的分析器105包括用于测量样本的测量硬件128和控制部分127.控制部分被配置为促使对存储在第一个中的第一精度管理样本的精度管理测量执行样品瓶130; 接收在测量硬件128中执行的第一样品瓶130的精度管理测量结果; 并且当精度管理测量的结果超出预定范围并且精度管理测量的结果超出预定范围的次数小于预定数量时，促使对精度管理测量的执行再次是第一个样品瓶130。版权所有（C）2013，JPO＆INPIT

34. 发明专利

JP2013024880A Analysis system, analyzer, and server computer 有权
标题翻译：分析系统，分析仪和服务器计算机
公开(公告)号：JP2013024880A
公开(公告)日：2013-02-04
申请号：JP2012162132
申请日：2012-07-20
申请人： Sysmex Corp , シスメックス株式会社
发明人： JAMES AUSDENMOORE , PETER OSELLA , RALPH TAYLOR
IPC分类号： G01N35/00
CPC分类号： G01N35/00613 , G06Q10/06395 , G06Q10/06398
摘要： PROBLEM TO BE SOLVED: To provide an analysis system capable of ensuring that samples are analyzed in correct procedures when the samples are analyzed.SOLUTION: An analyzer 105 comprises: a measuring hardware 128 for measuring a sample; and a first controller 127. The first controller 127 is configured to urge an operator of the analyzer to input whether or not the operator has completed operation training of the analyzer and to request a server 110 to confirm that the operator has completed the training if a fact that the training has been completed is input. The server 110 includes a second controller 129. The second controller is configured to receive the confirmation request from the analyzer, to determine whether or not the operator has completed the training, and to communicate a determination result to the analyzer. If the first controller 127 receives a determination result indicating that the operator has not completed the training from the server 110, measurement of samples by means of the hardware 128 is prohibited.
摘要翻译：要解决的问题：提供一种能够在分析样品时能够确保以正确程序分析样品的分析系统。解决方案：分析器105包括：用于测量样品的测量硬件128; 和第一控制器127.第一控制器127被配置为促使分析仪的操作者输入操作者是否已经完成了分析仪的操作训练，并且要求服务器110确认操作者已经完成了训练，如果培训已经完成的事实是输入。服务器110包括第二控制器129.第二控制器被配置为从分析器接收确认请求，以确定操作员是否已经完成了训练，并且将确定结果传送给分析器。如果第一控制器127接收到指示操作者尚未从服务器110完成训练的确定结果，则禁止通过硬件128对样本进行测量。版权所有（C）2013，JPO＆INPIT

35. 发明专利

JP2012233807A Specimen processing device 有权
标题翻译：标本加工设备
公开(公告)号：JP2012233807A
公开(公告)日：2012-11-29
申请号：JP2011103235
申请日：2011-05-02
申请人： Sysmex Corp , シスメックス株式会社
发明人： KUWANO KEISUKE , ARIYOSHI SHUNSUKE , SUGIYAMA TOMOMI
IPC分类号： G01N35/00
CPC分类号： G01N35/00663 , G01N35/00584 , G01N2035/00673 , G01N2035/00891 , G01N2035/009
摘要： PROBLEM TO BE SOLVED: To provide a specimen processing device capable of saving a user effort when the user releasing abnormality occurring in a device.SOLUTION: A menu screen A1 is displayed on a display section of a specimen processing device. When an error occurs in a measuring unit, an error button P31 is displayed. Also, a help dialog D1 is displayed above operation sections M1 and M2. The help dialog D1 includes an error message list D11 showing a detected error item and a detail procedure display button D13. When the detail procedure display button D13 is pressed, a corresponding page of an electric manual describing an operation procedure to release the error selected in the error message list D11 is displayed in a main region A20. Thus, a user can know the operation procedure to release the error without additionally referring to an instruction manual.
摘要翻译：要解决的问题：提供一种能够在用户释放在设备中发生异常的同时节省用户努力的检体处理装置。
解决方案：在样本处理装置的显示部分上显示菜单画面A1。当测量单元发生错误时，显示错误按钮P31。而且，在操作部M1和M2上方显示帮助对话D1。帮助对话框D1包括示出检测到的错误项目和详细过程显示按钮D13的错误消息列表D11。当按下详细过程显示按钮D13时，在主区域A20中显示描述用于释放在错误消息列表D11中选择的错误的操作过程的电动手册的对应页面。因此，用户可以知道操作过程来释放错误，而不另外参考使用说明书。版权所有（C）2013，JPO＆INPIT

36. 发明专利

JP2012228233A Method for assessing efficacy of combination chemotherapy, and program and device for assessing the same 有权
标题翻译：用于评估组合治疗效果的方法，以及用于评估其的程序和装置
公开(公告)号：JP2012228233A
公开(公告)日：2012-11-22
申请号：JP2011100184
申请日：2011-04-27
申请人： Sysmex Corp , シスメックス株式会社
发明人： KADONAKA CHIHIRO , HARADA SHU , OYAMA TOMOKO , TORIGOE YASUMITSU
IPC分类号： C12Q1/48 , C12M1/34 , G01N33/68
CPC分类号： C12Q1/485 , G01N33/573 , G01N33/57415 , G01N2333/91177 , G01N2800/52 , G06F19/18
摘要： PROBLEM TO BE SOLVED: To provide a method for assessing efficacy of combination of chemotherapy to a cancer patient with higher reliability.SOLUTION: The method for assessing efficacy of combination chemotherapy includes: a first obtaining process for obtaining a specific activity value of Cyclin Dependent Kinase (CDK) 1 and a specific activity value of CDK2 in a biological sample including a carcinoma cell collected from a cancer patient; a second obtaining process for obtaining a GSTπ expression level in the biological sample; and an assessment process for assessing the efficacy of the combination chemotherapy to the cancer patient based on the specific activity values of CDK1 and CDK2 obtained in the first obtaining process and the GSTπ expression level obtained in the second obtaining process.
摘要翻译：要解决的问题：提供一种评估化疗组合对具有更高可靠性的癌症患者的功效的方法。解决方案：联合化疗的疗效评估方法包括：获得细胞周期蛋白依赖性激酶（CDK）1的特异活性值的首次获得方法和生物样品中CDK2的比活性值，包括从癌症病人用于获得生物样品中GSTπ表达水平的第二获得方法; 以及基于在第一获得过程中获得的CDK1和CDK2的特异活性值和在第二获得过程中获得的GSTπ表达水平来评估组合化疗对癌症患者的功效的评估过程。版权所有（C）2013，JPO＆INPIT

37. 发明专利

JP2012217667A Biogenic substance measuring method 有权
标题翻译：生物物质测量方法
公开(公告)号：JP2012217667A
公开(公告)日：2012-11-12
申请号：JP2011086996
申请日：2011-04-11
申请人： Sysmex Corp , シスメックス株式会社
发明人： YOSHIKAWA YASUO , WATANABE TOSHIHIRO
IPC分类号： A61B5/151 , G01N21/78 , G01N27/416 , G01N27/49
CPC分类号： G01N21/31 , G01N33/66
摘要： PROBLEM TO BE SOLVED: To provide a method configured to effectively control in a simplifier manner any adverse influences from perspiration excreted from a skin currently measured when a biogenic substance from tissue fluid extracted through fine pores is measured.SOLUTION: The method for measuring a constituent of tissue fluid extracted from a test subject's skin includes steps of: forming a film having a water impermeability on the test subject's skin; forming fine pores in the skin coated with the film so as to penetrate through the film; extracting the tissue fluid from the test subject through the skin where the fine pores are formed, and storing the constituent to be measured and inorganic ions of the extracted tissue fluid; obtaining an ion information relating to a quantity of the stored inorganic ions; and obtaining a constituent information relating to a quantity of the stored constituent. an analysis value relating to the quantity of the constituent is obtained based on the ion information and the constituent information.
摘要翻译：要解决的问题：提供一种被配置为以简化方式有效地控制当通过细孔提取的来自组织流体的生物来源物质被测量时从当前测量的皮肤排出的汗液的任何不良影响。解决方案：从测试对象的皮肤中提取的组织液成分的测量方法包括以下步骤：在测试对象的皮肤上形成具有不透水性的膜; 在涂覆有薄膜的皮肤中形成细孔，以穿透膜; 通过形成细孔的皮肤从测试对象提取组织液，并将待测量的组分和提取的组织液的无机离子储存; 获得与所储存的无机离子的量有关的离子信息; 以及获得与所存储的成分的量相关的构成信息。基于离子信息和构成信息获得与成分量相关的分析值。版权所有（C）2013，JPO＆INPIT

38. 发明专利

JP2012211930A Pipette chip supply device and specimen analyzer 有权
标题翻译： PIPETTE芯片供应器件和样品分析仪
公开(公告)号：JP2012211930A
公开(公告)日：2012-11-01
申请号：JP2012178906
申请日：2012-08-10
申请人： Sysmex Corp , シスメックス株式会社
发明人： KOWARI TAKEO , IZUMI YUKIYOSHI
IPC分类号： G01N35/10
摘要： PROBLEM TO BE SOLVED: To provide a pipette chip supply device capable of conveying a pipette chip smoothly.SOLUTION: The pipette chip supply device includes: a storage part having a mounting opening at one end for storing a plurality of pipette chips for sucking specimens; a classification part for classifying one by one each pipette chip delivered from the storage part; a transfer part for transferring each pipette chip classified by the classification part by changing the attitude into a state with a mounting opening facing upward; and a detection part for detecting the pipette chip delivered from the classification part to the transfer part. When the detection part detects the pipette chip, the transfer part performs a transfer operation in the inverse direction to the transfer direction of the pipette chip and then performs a transfer operation to the transfer direction of the pipette.
摘要翻译：要解决的问题：提供能够平稳地输送移液管芯片的移液管芯片供给装置。移液管芯片供给装置包括：储存部，其一端具有用于储存多个用于吸取试样的移液管芯片的安装开口; 分类部件，用于逐个分类从存储部件传送的每个移液管芯片; 转印部件，用于通过将姿态改变成面向上的安装开口的状态来转印由分类部分分类的每个移液管芯片; 以及检测部，其检测从所述分类部向所述转印部输送的移液管芯。当检测部检测到移液管芯片时，转印部件沿与移液管芯片的传送方向相反的方向进行转印操作，然后对移液管的传送方向进行转印操作。版权所有（C）2013，JPO＆INPIT

39. 发明专利

JP2012194071A Specimen analysis apparatus 有权
标题翻译：样本分析仪
公开(公告)号：JP2012194071A
公开(公告)日：2012-10-11
申请号：JP2011058480
申请日：2011-03-16
申请人： Sysmex Corp , シスメックス株式会社
发明人： KATSUMI HIRONORI , FUKUZAKI TSUYOSHI
IPC分类号： G01N35/00
摘要： PROBLEM TO BE SOLVED: To provide a specimen analysis apparatus which is capable of suppressing bedewing water from being deposited onto a reagent container when setting the reagent container into a reagent storage.SOLUTION: A specimen analysis apparatus 1 comprises a reagent storage 10 in which a reagent container 300 is accommodated and a reagent in the accommodated reagent container 300 is cooled. The reagent storage 10 comprises: a housing 20 which is configured to open/close the upper part; reagent container tables 21 and 22 which are disposed within the housing 20 at an interval upward from the bottom of the housing 20 for placing the reagent container thereon; a first member 64 which is confronted to a side face of the reagent container 300 placed on the reagent container tables 21 and 22; and second members 78, 81 and 82 which are provided lower than the reagent container tables 21 and 22 and of which the thermal conductivity is higher than that of the first member.
摘要翻译：要解决的问题：提供一种当将试剂容器设置在试剂储存器中时能够抑制寝水被沉积在试剂容器上的样本分析装置。解决方案：样本分析装置1包括其中容纳有试剂容器300并且容纳的试剂容器300中的试剂被冷却的试剂储存器10。试剂储存器10包括：壳体20，其构造成打开/关闭上部; 试剂容器台21和22，其从壳体20的底部向上设置在壳体20内，用于将试剂容器放置在其上; 第一构件64面对设置在试剂容器台21,22上的试剂容器300的侧面。第二构件78,81和82设置在比试剂容器台21和22低的位置，其导热率高于第一构件的导热率。版权所有（C）2013，JPO＆INPIT

40. 发明专利

JP2012189552A Reagent preparation device, reagent preparation method and specimen processing device 审中-公开
标题翻译：试剂制备装置，试剂制备方法和样品处理装置
公开(公告)号：JP2012189552A
公开(公告)日：2012-10-04
申请号：JP2011055629
申请日：2011-03-14
申请人： Sysmex Corp , シスメックス株式会社
发明人： IKEDA MINORU , NAKANISHI TOSHIJI
IPC分类号： G01N35/00
CPC分类号： G01N35/00663 , G01N35/00613 , G01N35/00712 , G01N2035/00673 , Y10T436/12 , Y10T436/25
摘要： PROBLEM TO BE SOLVED: To provide a reagent preparation device, a reagent preparation method and a specimen processing device for reducing reagent disposal quantity while suppressing drop of operation efficiency of a device when both of a transient failure and a continuous failure are generated.SOLUTION: The reagent preparation device 4 includes: a reagent preparation part 4a which prepares a reagent; a conductivity sensor 402 which measures characteristics of the reagent prepared by the reagent preparation part 4a; and a control part 49 which disposes the reagent when a measurement result of the conductivity sensor 402 does not match a predetermined condition. The control part 49 stops a reagent preparation operation of the reagent preparation part 4a when number of times not to match the predetermined condition reaches a plurality of predetermined times, and makes the reagent preparation part 4a continue the reagent preparation operation when the number of times not to match the predetermined condition does not reach the plurality of predetermined times.
摘要翻译：要解决的问题：提供一种试剂制备装置，试剂制备方法和用于减少试剂处理量的试样处理装置，同时在产生瞬时故障和连续故障的同时抑制装置的操作效率的下降。试剂调制装置4包括：准备试剂的试剂调制部4a; 电导率传感器402，其测量由试剂调制部件4a制备的试剂的特性; 以及当电导率传感器402的测量结果与预定条件不匹配时配置试剂的控制部分49。当与规定条件不一致的次数达到多个规定次数时，控制部49停止试剂调制部4a的试剂调制动作，使试剂调制部4a在不进行试验的情况下继续试剂调制以匹配预定条件不达到多个预定时间。版权所有（C）2013，JPO＆INPIT

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