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    • 23. 发明专利
    • Method and apparatus find the center amplitude of pulses representing the particle size produced by sizing system based on aperture
    • 空值
    • JP2009506320A
    • 2009-02-12
    • JP2008528005
    • 2006-08-18
    • ベックマン コールター, インコーポレイテッド
    • ジェフリー エル. ローズ,
    • G01N15/14
    • H04L25/062G01N15/1227G01R29/023H03K5/1532
    • 自動化された血液学的なシステムにおいて利用されるような、粒子サイズの測定システムで使用するパイプラインデジタル処理回路は、コールター原理に基づいた電子的粒子分析システムの検出アパーチャのようなフローセル測定アパーチャを通過する粒子または細胞によって生成されるパルスの「中心」振幅を測定する。 本発明の回路は、半ピーク/半分の幅の方法によって、連続するパルスのサンプルを処理し、該半ピーク/半分の幅の方法は、各パルスが連続的にサンプリングされ、メモリに一時的に格納されると、各パルスを分析する。 格納の間のメモリ内のデータの同時分析は、パルスの所定の割合のピーク振幅におけるパルスの幅を特定する。 次に、このパルスの幅のデータは処理され、パルスの上昇縁の部分と下降縁の部分とにおける中間ピークの値の間のパルスの幅の中間点におけるパルスの振幅を決定する。
    • 与用于自动血液系统中的粒度测量系统一起使用的流水线数字处理电路测量由通过流动池测量孔径的颗粒或细胞产生的脉冲的“中心”幅度,例如检测孔径 基于Coulter原理的电子粒子分析系统。 本发明的电路通过分析每个脉冲作为其连续采样并临时存储在存储器中的半峰/半角方法来处理连续脉冲样本。 在存储器期间对存储器中的数据的并行分析以脉冲的峰值幅度的规定百分比(例如,50%)来定位脉冲宽度。 然后处理该脉冲宽度数据,以确定脉冲宽度的中点处的脉冲幅度,其脉冲的上升沿和下降沿部分之间的中间峰值之间。
    • 26. 发明专利
    • Particle counter
    • 颗粒计数器
    • JPS59148849A
    • 1984-08-25
    • JP2273783
    • 1983-02-16
    • Hitachi Ltd
    • HORIUCHI HIDEYUKI
    • G01N15/12
    • G01N15/1227
    • PURPOSE:To enable decision of a split pulse and plural simultaneous pass pulses as well as the passing condition of an orifice by using a mean for measuring the change in electric resistance by the passage of a particle in the very small orifice. CONSTITUTION:The electrical pulse by the passage of a particle detects the presence of the particle in an analog comparator 21. The split of the electric pulse is accomplished by differentiating the electric pulse and passing the same through an absolute value circuit 28. Comparators 29, 30 are used to detect the split pulse from the output (B) of the circuit 28. A comparing level L3 is used for detection of the split pulse and a comparing level L2 for detection of the size of the trough. The number of pulses when a particle exists is counted with a counter circuit 25 by the output D of the comparator 29. When the Q output of an FF 26 goes from a 0 to a 1, the split pulse or the double pulses by simultaneous passage are eventually detected. If the count value of a counter circuit 14 becomes considerbly larger than the anticipated number of simultaneous passage, the extreme clogging in the orifice is detected. As a result, the passage state of the orifice is decided.
    • 目的:通过使用用于通过非常小的孔口中的颗粒通过来测量电阻变化的平均值来使分裂脉冲和多个同时通过脉冲以及孔口的通过条件成为可能。 构成:通过粒子通过的电脉冲检测模拟比较器21中颗粒的存在。电脉冲的分割通过使电脉冲微分并通过绝对值电路28来实现。比较器29, 30用于检测来自电路28的输出(B)的分离脉冲。比较电平L3用于分离脉冲的检测和用于检测波谷尺寸的比较电平L2。 通过比较器29的输出D用计数器电路25对存在粒子的脉冲数进行计数。当FF 26的Q输出从0变为1时,分流脉冲或同时通过的双脉冲 最终被检测到。 如果计数器电路14的计数值明显大于预期的同时通过次数,则检测孔中的极端堵塞。 结果,确定孔的通过状态。
    • 27. 发明专利
    • Particle size analyzer
    • 颗粒尺寸分析仪
    • JPS58221149A
    • 1983-12-22
    • JP10412482
    • 1982-06-17
    • Toa Medical Electronics Co Ltd
    • OKADA NORIHIROHAYASHI MASAYOSHI
    • G01N15/10G01N15/12G01N15/14G01N33/49
    • G01N15/1227
    • PURPOSE:To observe a particle size distribution curve of each component at the same time, by driving the particle sizes to be measured into plural ranges, measuring and synthesizing them, and regulating the number of particles to be measured to an almost same value by changing the measurement time. CONSTITUTION:The present analyzer comprises a particle volume detector 1 for detecting the particle in accordance with the electric difference, etc. between the particle and a particle suspending liquid and producing a signal proportional to the size of particle, a variable amplifier 2 for amplifying the signal of the particle sent from the detector 1, an AD converter 3, a calculation circuit 4, an input device 5, and a display printer 6. The particle sizes to be measured are divided into plural ranges, a size in each range is measured by changing over the sensitivity and synthesized, or by changing over the sensitivity as well as changing the measuring time to regulate the number of the particles to be measured to an almost same value. Hence, the particle size distribution curve of each component in each size range can be observed at the same time.
    • 目的:为了同时观察各组分的粒度分布曲线,通过将待测量的粒径驱动到多个范围内,测量和合成它们,并通过改变测量方法将待测量的颗粒数量调节到几乎相同的值 测量时间。 构成:本分析装置包括:粒子体积检测器1,用于根据粒子与粒子悬浮液之间的电差等检测粒子,并产生与粒子大小成正比的信号;可变放大器2,用于放大 从检测器1发送的粒子的信号,AD转换器3,计算电路4,输入装置5和显示打印机6.将要测量的粒子分成多个范围,测量每个范围内的尺寸 通过改变灵敏度和合成,或通过改变灵敏度以及改变测量时间来将待测量的颗粒的数量调节到几乎相同的值。 因此,可以同时观察各尺寸范围内的各成分的粒径分布曲线。
    • 28. 发明专利
    • Particle analyzing device
    • 颗粒分析装置
    • JPS5779434A
    • 1982-05-18
    • JP15499480
    • 1980-11-04
    • Toa Medical Electronics Co Ltd
    • HAYASHI MASAYOSHIMATSUMOTO HIDEAKI
    • G01N15/12
    • G01N15/1227
    • PURPOSE:To measure the expansion rate, expansion time and collapsion time of particles accurately by storing data in a read-write memory and operating the same. CONSTITUTION:Particles are detected by passing a sample 3 of blood or the like through fine pores 3 and are converted to pulse signals in a detecting circuit 11. Said signals are subjected to AD conversion in an AD conversion circuit 12 and are stored in a read-write memory 15. The operating sequence of the circuit 13 is stored in a read-only memory 14, and cumulative value and number of particles are called from the memory 15. Mean particle volume (MPV) is operated and again stored in the memory 15. The average value of the MPVs of the previous time and the time before the previous time and the average value of the MPVs of this time and the next time are compared by repeating this operation, and the expansion rate, expansion time and collapsion time of particles are measured. if the number of particles decreases, variance is produced and therefore when the preset set point is attained, the operation of a display device 16 and a recorder 17 is inhibited by a record removing command circuit 18. In this way, the examination of blood diseases or the like is accomplished accurately.
    • 目的:通过将数据存储在读写存储器中并进行操作,从而准确测量微粒的扩展速率,扩展时间和折叠时间。 构成:通过使血液等的样品3通过细孔3检测出粒子,并在检测电路11中转换为脉冲信号。所述信号在AD转换电路12中进行AD转换,并存储在读取 写存储器15.电路13的操作顺序存储在只读存储器14中,并且从存储器15调用累积值和粒子数。平均粒子体积(MPV)被操作并再次存储在存储器 通过重复该操作来比较先前时间和先前时间的MPV的平均值以及该时间和下一次的MPV的平均值,并且扩展速率,展开时间和折叠时间 的颗粒。 如果粒子的数量减少,则产生变化,因此当达到预设的设定点时,由记录去除指令电路18禁止显示装置16和记录器17的操作。这样,血液病 或类似物被精确地完成。