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3. 发明授权

EP4125752B1 HYDROGEL COMPOSITIONS AND PREPARATION THEREOF 有权
公开(公告)号：EP4125752B1
公开(公告)日：2024-05-08
申请号：EP21715267.7
申请日：2021-03-30
IPC分类号： A61F13/00 , A61L15/60 , C08J3/075
CPC分类号： C08J3/075 , C08J2333/1420130101 , A61F13/00063 , A61L15/60 , A61L26/008 , A61L26/0014 , A61L15/24 , A61L26/0066 , A61L15/44 , A61L15/58 , A61L2300/40420130101 , A61L2300/20620130101 , A61F13/01017

4. 发明授权

EP4083115B1 PREPARATION METHOD OF SUPER ABSORBENT POLYMER 有权
公开(公告)号：EP4083115B1
公开(公告)日：2024-05-08
申请号：EP21886838.8
申请日：2021-10-28
IPC分类号： C08J3/075 , C08J3/24 , C08J3/12 , A61L15/60 , B01J20/26 , B01J20/28
CPC分类号： C08J3/12 , C08J3/075 , C08J3/245 , A61L15/60 , C08J2333/0220130101 , B01J2220/6820130101 , B01J20/267 , B01J20/28011

5. 发明授权

EP3740525B1 POROUS AFFINITY HYDROGEL PARTICLES FOR REDUCING THE BIOAVAILABILITY OF SELECTED BIOLOGICAL MOLECULES 有权转让
公开(公告)号：EP3740525B1
公开(公告)日：2024-05-01
申请号：EP19714835.6
申请日：2019-01-18
IPC分类号： C08J3/075 , A61K47/36 , A61K9/16 , A61K9/00
CPC分类号： A61K9/0019 , A61K47/36 , A61K9/1641 , A61K9/1652 , C08J3/075 , C08J2300/1220130101 , C08J2300/1420130101 , C08J2305/0220130101 , C08J2305/0820130101 , C08J2371/0220130101

6. 发明公开

EP4351671A2 HYDROLYTICALLY DEGRADABLE HYDROGELS AND USES THEREOF 审中-实审
公开(公告)号：EP4351671A2
公开(公告)日：2024-04-17
申请号：EP22812141.4
申请日：2022-05-26
申请人： Georgia Tech Research Corporation
发明人： GARCIA, Andres J. , CORONEL, Maria M.
IPC分类号： A61L27/52 , A61L27/18 , C08J3/075 , C08J3/24 , C08K5/11
CPC分类号： C08J3/075 , C08J2371/0220130101 , A61L27/52 , A61L27/18 , A61L27/54 , A61L27/38 , A61L27/56 , A61L2400/0620130101 , A61L15/60 , A61L15/44 , A61L15/46 , A61L15/425 , A61K9/0024 , A61K9/06 , A61K47/34

7. 发明授权

EP3795609B1 CATIONIC MUCIC ACID POLYMER-BASED DELIVERY SYSTEMS 有权转让
公开(公告)号：EP3795609B1
公开(公告)日：2024-04-03
申请号：EP20186381.8
申请日：2016-06-13
发明人： DAVIS, Mark E. , PAN, Dorothy
IPC分类号： C08G65/34 , C08G65/333 , C08G63/06 , C08J3/12 , C08J5/00 , C08J3/075 , C08L67/04 , C08L71/02

8. 发明公开

EP4317356A1 A TYPE OF TRIPLE NETWORK COOLING HYDROGEL WITH HIGH COMPRESSIVE AND ELASTIC 审中-实审
公开(公告)号：EP4317356A1
公开(公告)日：2024-02-07
申请号：EP23183680.0
申请日：2023-07-05
申请人： Honeywell International Inc.
发明人： WANG, Yuyan , ZHOU, Tianqi , HOU, Zhixiong , LUO, Rui , LIN, Ling , GU, Zheng , ZHOU, Peng , LIU, Le , ZHAO, Qingyi , DUDELZAK, Marc
IPC分类号： C09K5/06 , C08J3/075 , C08L29/04
摘要： The invention provides triple crosslinked cooling hydrogel compositions of high tensile strength, high compressibility, high elasticity, and long cooling period and methods of making the compositions. The compositions are useful in clothing and equipment for wear in high solar radiation environments and high temperature environments.

9. 发明公开

EP4306550A1 HYDROGELS FOR CELL THERAPY 无效
公开(公告)号：EP4306550A1
公开(公告)日：2024-01-17
申请号：EP22184569.6
申请日：2022-07-13
申请人： Adocia
发明人： GEISSLER, Alexandre , LAURENT, Nicolas , PLANCQ, Baptiste , SOULA, Gérard , ELOY, Marie-Rose
IPC分类号： C08B37/02 , A61K47/36 , A61L27/52 , C08J3/075 , C08L5/02
摘要： The invention concerns cross-linked dextran polymer Dx bearing anionic groups wherein the at least divalent radical L(-)i is covalently bound to the dextran polymer backbone with i -W- radicals, wherein,
- L(-) i is a linear or branched polyether
- i is the valence of L and the number of -W- radicals bound to the dextran polymer and is an integer comprised from 2 to 8 (2 ≤ i ≤ 8),
- -W- is a radical comprising at least a radical alkyl linear or branched and optionally comprising heteroatoms such as oxygen, nitrogen or sulfur, aromatic cycles, polyether derivatives and that does not comprise two or more alpha aminoacid residues in particular linked by peptidic bond(s).

It also concerns the dextran polymers before the crosslinking reaction and the process to synthetize a cross-linked dextran polymer according to the invention, into the form of a hydrogel.
It also concerns a hydrogel comprising the crosslinked dextran polymer of the invention and/or a hydrogel that further comprises biological cells.
It also concerns therapeutic use of the hydrogel according to the invention for treating a disorder or disease in a mammal wherein the disorder or disease is due to lack or malfunction of endocrine function of pancreas organ and an implant comprising the hydrogel according to the invention.

10. 发明公开

EP4306548A1 HYDROGELS FOR CELL THERAPY 无效
公开(公告)号：EP4306548A1
公开(公告)日：2024-01-17
申请号：EP22184567.0
申请日：2022-07-13
申请人： Adocia
发明人： GEISSLER, Alexandre , LAURENT, Nicolas , PLANCQ, Baptiste , SOULA, Gérard , ELOY, Marie-Rose
IPC分类号： C08B37/02 , A61K47/36 , A61L27/52 , C08J3/075 , C08L5/02 , C08B37/08
摘要： The invention concerns an hydrogel comprising:
- biological cells,
- a non crosslinked hyaluronic acid in the form of a solution, and
- a crosslinked dextran polymer Dx bearing anionic groups wherein the at least divalent radical L(-) i is covalently bound to the dextran polymer backbone with i W radicals, wherein,
- L(-) i is a linear or branched polyether
- i is the valence of L and the number of W radicals bound to the dextran polymer and is an integer comprised from 2 to 8 (2 ≤ i ≤ 8),
- -W- is a radical comprising at least a radical alkyl linear or branched and optionally comprising heteroatoms such as oxygen, nitrogen or sulfur, aromatic cycles, polyether derivatives and that does not comprise two or more alpha aminoacid residues in particular linked by peptidic bond(s).
It also concerns the therapeutic use of the hydrogel according to claim 1, for treating a disorder or disease in a mammal wherein the disorder or disease is due to lack or malfunction of endocrine function of pancreas organ.
It also concerns an implant comprising the hydrogel according to any one of claims 1 to 2.

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