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1. 发明公开

EP1890114A1 FLOW RATE METER AND FLOW RATE CONTROL SYSTEM USING THE SAME 有权
标题翻译： STRÖMUNGSGESCHWINDIGKEITSMESSERUNDSTRÖMUNGSGESCHWINDIGKEITSSTEUERSYSTEMDAMIT
公开(公告)号：EP1890114A1
公开(公告)日：2008-02-20
申请号：EP06731008.6
申请日：2006-04-03
申请人： Surpass Industry Co., Ltd.
发明人： USHIGUSA, Yoshihiro, C/O Surpass Industry Co., Ltd , IGARASHI, Hiroki, C/O Surpass Industry Co., Ltd , HASUNUMA, Masahiro, C/O Surpass Industry Co., Ltd
IPC分类号： G01F1/42 , G01F1/34 , G01F1/48 , G05D7/06
CPC分类号： G05D7/0635 , G01F1/42 , G01F1/48 , Y10T137/7725 , Y10T137/87217
摘要： Provided are a flow meter and a flow-rate control system using the same that is capable of measuring a flow rate in a minute flow-rate region with excellent measurement accuracy by preventing or suppressing the generation of bubbles and in which accumulation of the fluid and the bubbles is less likely to occur. The flow meter is for measuring a minute flow rate of a fluid flowing through a fluid channel whose outlet environment is set to constant pressure, the flow meter including a flow-rate measurement conduit portion having a predetermined length connected to an outlet-side end of the fluid channel 1 and whose outlet environment is set to constant pressure by setting the cross-sectional area of a channel smaller than the fluid channel; a pressure sensor for detecting the pressure of the fluid at the upstream side of the flow-rate measurement conduit portion by being disposed near an outlet of the fluid channel 1; and a pressure-detection control unit 4 for calculating a flow rate from a fluid pressure detected at the pressure detection part.
摘要翻译：提供一种流量计和流量控制系统，其使用该流量计和流量控制系统，其能够通过防止或抑制气泡的产生来测量具有优异的测量精度的微小流量区域中的流量，并且其中流体和气泡不太可能发生。所述流量计用于测量流过流出通道的流体的微小流量，所述流体通道的出口环境设定为恒定压力，所述流量计包括具有预定长度的流量测量导管部分，流体通道1的出口环境通过将通道的横截面积设定为小于流体通道而设定为恒定压力; 压力传感器，用于通过设置在流体通道1的出口附近来检测流量测量导管部分的上游侧的流体的压力; 以及压力检测控制单元4，用于根据在压力检测部分检测到的流体压力来计算流量。

2. 发明授权

EP1007973B1 MICROVOLUME LIQUID HANDLING SYSTEM 失效
标题翻译：微流体液体处理系统
公开(公告)号：EP1007973B1
公开(公告)日：2004-12-01
申请号：EP98915459.6
申请日：1998-04-08
申请人： Packard Instrument Company, Inc.
发明人： PELC, Richard, E. , CHIBUCOS, Nicholas, S. , PAPEN, Roeland, F. , MAYER, Wilhelm
IPC分类号： G01N35/10 , B01L3/02
CPC分类号： G01N35/1016 , B01J2219/00378 , C40B60/14 , G01F1/48 , G01F3/00 , G01N2035/00237 , G01N2035/1018 , G01N2035/1025 , G01N2035/1039 , G01N2035/1041
摘要： A microvolume liquid handling system includes a microdispenser employing a piezoelectric transducer attached to a glass capillary, a positive displacement pump for priming and aspirating transfer liquid into the microdispenser, controlling the pressure of the liquid system, and washing the microdispenser between liquid transfers, and a pressure sensor to measure the liquid system pressure and produce a corresponding electrical signal. The pressure signal is used to verify and quantify the microvolume of transfer liquid dispensed and is used to perform automated calibration and diagnostics on the microdispenser. In another embodiment of the microvolume liquid handling system, a system reservoir is connected with tubing to a pressure control system for controlling the liquid system pressure in the system reservoir. The system reservoir is coupled to one or more microdispensers through a distribution tube having a branched section for each microdispenser. In this embodiment, each microdispenser is coupled to its own flow sensor and to enable a system controller to respectively measure and control the flow of liquid in the each microdispenser. Dispensing of a single sub-nanoliter drop can be detected in real time. As the result of dispensing the liquid in sub-nanoliter droplets, the dispensed volume can be precisely controlled. The dispenser automatically detects the liquid surface of the transfer liquid, automatically aspirate, analyze desired volume of the transfer liquid, dispense the transfer liquid without contacting the destination vessel or its contents, and automatically wash off the transfer liquid from dispensing system after each transfer. This system is capable of automatically sensing liquid surfaces, aspirating liquid to be transferred, and then dispensing small quantities of liquid with high accuracy, speed and precision. The system is pulsated at high frequency to prevent or eliminate clogging. Immiscible liquid between the transfer liquid and the system liquid reduces the required amount of transfer liquid needed for dispensing.
摘要翻译：微量液体处理系统包括使用连接至玻璃毛细管的压电换能器的微分配器，用于将转移液体灌注并吸入微量分配器中的正排量泵，控制液体系统的压力以及在液体转移之间清洗微分配器，压力传感器来测量液体系统压力并产生相应的电信号。压力信号用于验证和量化分配的转移液体的微量，并用于对微分配器进行自动校准和诊断。在微体积液体处理系统的另一个实施例中，系统容器通过管连接到用于控制系统容器中的液体系统压力的压力控制系统。系统贮存器通过具有用于每个微分配器的分支部分的分配管与一个或多个微分配器连接。在该实施例中，每个微分配器耦合到其自己的流量传感器并且使系统控制器能够分别测量和控制每个微分配器中的液体流量。可以实时检测单次亚纳升滴的分配。由于以亚纳升液滴分配液体，可以精确控制分配体积。分配器自动检测转印液体的液面，自动吸取，分析转印液体的所需体积，分配转印液体而不接触目的容器或其内容物，并在每次转印后自动从分配系统清洗转印液体。该系统能够自动检测液体表面，吸取要传送的液体，然后以高精度，高速度和精确度分配少量液体。系统以高频脉动，以防止或消除堵塞。转印液体和系统液体之间的不混溶液体减少了分配所需的转印液体量。

3. 发明公开

EP1181099A4 DISPENSING LIQUID DROPS ONTO POROUS BRITTLE SUBSTRATES 无效
标题翻译：供应液滴在多孔基材上SPRÖDBRÜCHIGE
公开(公告)号：EP1181099A4
公开(公告)日：2002-09-04
申请号：EP01942582
申请日：2001-01-11
申请人： PACKARD INSTRUMENT CO INC
发明人： PAPEN ROELAND E
IPC分类号： B01L3/02 , C40B60/14 , G01F1/48 , G01F3/00 , G01N35/00 , G01N35/10 , B01L3/00 , G01N1/10
CPC分类号： B01L3/0268 , B01J2219/00378 , B01J2219/00527 , B01J2219/00596 , B01J2219/00605 , B01J2219/0061 , B01J2219/00612 , B01J2219/0063 , B01J2219/00659 , B01J2219/00689 , B01J2219/00691 , C40B60/14 , G01F1/48 , G01F3/00 , G01N35/1016 , G01N35/1065 , G01N2035/00237 , G01N2035/1018 , G01N2035/1025 , G01N2035/1034 , G01N2035/1039 , G01N2035/1041 , Y10T436/2575
摘要： A system for aspirating and ejecting microvolume drops (26) of liquid onto porous sites of a substrate wafer includes a microdispenser (16) employing a piezoelectric transducer (60) attached to a glass capillary (62), a means for priming and aspirating transfer liquid (24) into the microdispenser (16), for controlling the pressure of the system liquid (20), and for washing the microdispenser (16) between liquid transfers, and a pressure sensor (14) to measure the system liquid pressure and produce a corresponding electrical signal. The drops are generally in the 10 to 100 micron range and the pores are generally 10 to 10,000 times smaller than the diameter of the drops deposited thereon. The resulting spots are uniform, and only slightly larger in diameter of the drops. The drops are ejected from a distance greater than the diameter of the drops, thus avoiding any contact with the dispenser that could damage the wafer. The system detects dispensing of a drop onto the reaction site.

4. 发明授权

EP2748565B1 DURCHFLUSSSENSOR 有权转让
公开(公告)号：EP2748565B1
公开(公告)日：2017-08-16
申请号：EP12756672.7
申请日：2012-08-21
申请人： Reseachem GmbH
发明人： BERGER, Stefan , ZUMBRUNNEN, Simon , MARMET, Philip , HASLEBACHER, Philipp , SCHÄR, Manfred
IPC分类号： G01F1/42 , G01F13/00
CPC分类号： G01F9/00 , G01F1/34 , G01F1/363 , G01F1/42 , G01F1/48 , G01F1/50 , G01F15/003 , G01F15/005 , G01N11/02 , G01N2011/006

5. 发明公开

EP2748565A1 DURCHFLUSSSENSOR 有权转让
公开(公告)号：EP2748565A1
公开(公告)日：2014-07-02
申请号：EP12756672.7
申请日：2012-08-21
申请人： Reseachem GmbH
发明人： BERGER, Stefan , ZUMBRUNNEN, Simon , MARMET, Philip , HASLEBACHER, Philipp , SCHÄR, Manfred
IPC分类号： G01F1/42 , G01F13/00
CPC分类号： G01F9/00 , G01F1/34 , G01F1/363 , G01F1/42 , G01F1/48 , G01F1/50 , G01F15/003 , G01F15/005 , G01N11/02 , G01N2011/006
摘要： Proposed is a flow sensor (10), in particular for single use, having at least three measurement chambers (11, 15, 19), which are arranged one behind the other and are interconnected in each case by a flow resistance. At least two of the flow resistances have a different coefficient of pressure loss. A pressure measuring means (12, 16, 20) is provided for each measurement chamber, which pressure measuring means (12, 16, 20) is suitable for measuring the pressure in the measurement chamber. An electromagnetically actuatable valve arrangement (50) can be connected downstream of the flow sensor.
摘要翻译：提出了一种流量传感器（10），特别是单次使用的流量传感器（10）具有至少三个测量室（11,15,19），这些测量室一个接一个设置，并且在每种情况下都通过流动阻力相互连接。至少两个流动阻力具有不同的压力损失系数。为每个测量室提供压力测量装置（12,16,20），该压力测量装置（12,16,20）适用于测量测量室中的压力。电磁致动阀装置（50）可以连接在流量传感器的下游。

6. 发明授权

EP0943076B1 MIKROMECHANISCH GEFERTIGTE FLUSSRESTRIKTIONSVORRICHTUNG 失效
标题翻译： MICRO机械MADE限流器件
公开(公告)号：EP0943076B1
公开(公告)日：2000-05-10
申请号：EP97951190.4
申请日：1997-11-13
申请人： FRAUNHOFER-GESELLSCHAFT ZUR FÖRDERUNG DER ANGEWANDTEN FORSCHUNG E.V.
发明人： WOIAS, Peter,Dr.
IPC分类号： G01F1/38 , F15C5/00
CPC分类号： G01F1/48 , G01F1/383 , G01F1/40
摘要： The invention concerns a micromechanically produced flow-restriction device in which a through-opening (12) is formed in a first main surface of a substrate (10). Formed in a second main surface of the substrate (10) is a duct (16) which is connected for flow purposes to the through-opening (12). A membrane (22) formed in the substrate (10) is connected for flow purposes to the through-opening (12) and comprises a membrane electrode (26) formed at least on the membrane (22). A cover device (30) is mounted on the second main surface of the substrate (10) such that the cover device (30) and the duct (16) define a flow resistance means for the flow-restriction device, the cover device (30) comprising a counter electrode (32) which lies opposite and at a spacing from the membrane electrode (26), such that the membrane electrode (26) and the counter electrode (32) define a capacitive pressure sensor.

7. 发明公开

EP0069173A1 Method and apparatus for measuring and controlling volumetric flow rate of gases in a line 失效
标题翻译：用于测量和控制气体中的管的体积流量的方法和装置。
公开(公告)号：EP0069173A1
公开(公告)日：1983-01-12
申请号：EP81302921.2
申请日：1981-06-29
申请人： BADGER METER, INC.
发明人： Kennedy, Lyn Richards
IPC分类号： G01F1/36
CPC分类号： G01F1/48 , G01F1/363
摘要： Disclosed is a method and apparatus for measuring and controlling volumetric flow rate of gases, and especially for delivering gases at a selected and measured volumetric flow rate. The apparatus includes a measurement chamber (14) of fixed volume in a flow line (11), a controllable inlet valve (15) upstream from the chamber, and flow regulator means (12, 13) for establishing constant flow output downstream from the chamber. Also provided are measuring and control equipment including a pressure sensor (16) in the chamber, means (17) for controlling operation of the inlet valve, timing means, and means for calculating volumetric flow rate. The method involves closing the inlet valve at a chosen time for a selected interval, to interrupt flow into the measurement chamber, while maintaining constancy of flow out of the chamber. During at least part of the interval in which the inlet valve is closed, the pressure decrease is measured, and the rate of pressure decrease is calculated by dividing the measured pressure drop by the time measured by the timing means. The thus calculated rate of fall of pressure is directly related to the volumetric flow rate, which is thus determined. If the nature of the gas and the flow conditions are such that the supercompressibility of the gas should be taken into account, rate of pressure fall is determined at two time intervals. If the two rates are the same, no correction is needed. If they differ, a supercompressibility correction factor is applied to the calculation of rate of pressure fall.
摘要翻译：公开的是用于测量和控制气体的体积流率，和爱尤其用于在选择和测量的体积流动速率递送气体的方法和装置。该装置包括一个流动管线（11），可控制的入口阀（15），其固定容积的测量腔（14）上游的腔室，和流量调节器装置（12，13），用于从所述腔室下游建立恒定流量输出，这样提供了用于控制操作所述入口阀的，定时装置被测量和控制设备，包括在所述腔室的装置（17）的压力传感器（16），以及用于计算体积流量。该方法包括关闭所述入口阀在一选定的时间间隔选择的时间，以中断流入测量室，同时保持流量恒定的流出腔室。在其中入口阀被关闭的时间间隔的至少一部分，所述压力减小被测量，并且压力下降率除以由定时装置测量的时间所测量的压降来计算。的压力下降的这样计算出速率直接相关的体积流动速率，在所有其因此确定性开采。如果被检查并在气体的超压缩应考虑到，速率压力降的气体和流动条件的性质确定的开采在两个时间间隔。如果这两个利率都是一样的，不需要校正。如果他们分开，一个超压缩校正因子应用到压降率的计算。

8. 发明公开

EP4399493A1 SYSTÈME DE MESURE DE DÉBIT DE LIQUIDE DANS UNE CANALISATION MICRO-FLUIDIQUE 审中-公开
公开(公告)号：EP4399493A1
公开(公告)日：2024-07-17
申请号：EP22735422.2
申请日：2022-06-27
申请人： MICROFLUIDICS INNOVATION CENTER
发明人： PLECIS, Adrien , MCMILLAN, Alexander , VELVE-CASQUILLAS, Guilhem , FARIN, Eric
IPC分类号： G01F1/36 , G01F1/48 , B01L3/00
CPC分类号： G01F1/363 , G01F1/48 , B01L3/502715 , B01L2300/066320130101 , B01L2200/14620130101 , B01L2400/08220130101

9. 发明公开

EP3227756A1 WIRELESS FLOW RESTRICTOR OF A FLOWMETER 审中-公开
标题翻译：流量计的无线流量限制器
公开(公告)号：EP3227756A1
公开(公告)日：2017-10-11
申请号：EP15798616.7
申请日：2015-11-10
申请人： Illinois Tool Works Inc.
发明人： ALTONJI, Robert W.
IPC分类号： G05D7/06 , G01F1/30 , G01F1/50 , G01F1/684 , G01F15/00 , G01F1/88 , G01F25/00 , G01F5/00
CPC分类号： G05D7/0635 , F15D1/10 , G01F1/40 , G01F1/48 , G01F1/6842 , G01F1/6847 , G01F1/88 , G01F15/005
摘要： The disclosed embodiments include a wireless restrictor that may be used as a laminar flow element in a flow meter or a mass flow controller. Embodiments of the wireless restrictor include a single machined part that contains both the features of a tapered restrictor and crushable positioning protrusions.
摘要翻译：所公开的实施例包括可用作流量计或质量流量控制器中的层流元件的无线限流器。无线限制器的实施例包括单个机加工零件，其包含锥形限制器和可破碎定位突起的特征。

10. 发明公开

EP2869761A2 DISPOSITIF DE MESURE D'UN FLUX GAZEUX POUR L'IMAGERIE MEDICALE 审中-公开
标题翻译：用于测量气体流的医学图像
公开(公告)号：EP2869761A2
公开(公告)日：2015-05-13
申请号：EP13756527.1
申请日：2013-06-26
申请人： ISP System
发明人： SAUVAGEOT, Paul , BRESCON, David , CAZALET, Jean-Marc
IPC分类号： A61B5/087 , G01F1/48 , G01F1/50
CPC分类号： A61M16/0003 , A61B5/055 , A61B5/087 , A61B5/091 , A61B6/032 , A61B6/037 , A61B6/4417 , A61B2562/0247 , A61B2562/16 , A61M16/0057 , A61M16/1075 , A61M2016/0027 , A61M2205/3673 , G01F1/40 , G01F1/48 , G01F1/50
摘要： The invention concerns a measuring device (3) for generating a differential pressure representative of the flow rate of a gas flow for medical imaging, comprising; a central body (8) provided with longitudinal channels (4) in communication with an inlet (5) and an outlet (6) of the gas stream, a casing (9) surrounding the central body, and seals (7a, 7b, 7c, 7d) delimiting a first space (10) for measuring an upstream pressure and a second space (11) for measuring a downstream pressure, each in communication with at least one of the longitudinal channels, and a third space (12) for heating up the central body. The invention also concerns a device for detecting the position of a moving area of the body of a patient, analysed by medical imaging, and a medical imaging apparatus incorporating such a detection device.

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